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Items: 1 to 50 of 98

1.

Regionalized nervous system in Hydra and the mechanism of its development.

Noro Y, Yum S, Nishimiya-Fujisawa C, Busse C, Shimizu H, Mineta K, Zhang X, Holstein TW, David CN, Gojobori T, Fujisawa T.

Gene Expr Patterns. 2019 Jan;31:42-59. doi: 10.1016/j.gep.2019.01.003. Epub 2019 Jan 21.

PMID:
30677493
2.

A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1-insensitive models of triple-negative breast cancer.

Cheng N, Watkins-Schulz R, Junkins RD, David CN, Johnson BM, Montgomery SA, Peine KJ, Darr DB, Yuan H, McKinnon KP, Liu Q, Miao L, Huang L, Bachelder EM, Ainslie KM, Ting JP.

JCI Insight. 2018 Nov 15;3(22). pii: 120638. doi: 10.1172/jci.insight.120638.

3.

Technologies for Innovative Monitoring to Reduce Blood Pressure and Change Lifestyle Using Mobile Phones in Adult and Elderly Populations (TIM Study): Protocol for a Randomized Controlled Trial.

Fuchs SC, Harzheim E, Iochpe C, David CN, Gonçalves MR, Sesin GP, Costa CM, Moreira LB, Fuchs FD.

JMIR Res Protoc. 2018 Aug 7;7(8):e169. doi: 10.2196/resprot.9619.

4.

Effectiveness of low-dose diuretics for blood pressure reduction to optimal values in prehypertension: a randomized clinical trial.

Fuchs FD, Fuchs SC, Poli-de-Figueiredo CE, Figueiredo Neto JA, Scala LCN, Vilela-Martin JF, Moreira LB, Chaves H, Mota Gomes M, de Sousa MR, Silva RPE, Castro I, Cesarino EJ, Sousa ALL, Alves JG, Steffens AA, Brandão AA, Bortolotto LA, Afiune Neto A, Nóbrega AC, Franco RS, Sobral Filho DC, Nobre F, Schlatter R, Gus M, De David CN, Rafaelli L, Sesin GP, Berwanger O, Whelton PK.

J Hypertens. 2018 Apr;36(4):933-938. doi: 10.1097/HJH.0000000000001624.

PMID:
29227377
5.

A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination.

Junkins RD, Gallovic MD, Johnson BM, Collier MA, Watkins-Schulz R, Cheng N, David CN, McGee CE, Sempowski GD, Shterev I, McKinnon K, Bachelder EM, Ainslie KM, Ting JP.

J Control Release. 2018 Jan 28;270:1-13. doi: 10.1016/j.jconrel.2017.11.030. Epub 2017 Nov 21.

6.

Overweight and Abdominal Obesity Association with All-Cause and Cardiovascular Mortality in the Elderly Aged 80 and Over: A Cohort Study.

David CN, Mello RB, Bruscato NM, Moriguchi EH.

J Nutr Health Aging. 2017;21(5):597-603. doi: 10.1007/s12603-016-0812-0.

PMID:
28448093
7.

NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes.

Freeman L, Guo H, David CN, Brickey WJ, Jha S, Ting JP.

J Exp Med. 2017 May 1;214(5):1351-1370. doi: 10.1084/jem.20150237. Epub 2017 Apr 12.

8.

Live imaging of mitochondrial dynamics in CNS dopaminergic neurons in vivo demonstrates early reversal of mitochondrial transport following MPP(+) exposure.

Dukes AA, Bai Q, Van Laar VS, Zhou Y, Ilin V, David CN, Agim ZS, Bonkowsky JL, Cannon JR, Watkins SC, Croix CM, Burton EA, Berman SB.

Neurobiol Dis. 2016 Nov;95:238-49. doi: 10.1016/j.nbd.2016.07.020. Epub 2016 Jul 22.

9.

GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii.

David CN, Frias ES, Szu JI, Vieira PA, Hubbard JA, Lovelace J, Michael M, Worth D, McGovern KE, Ethell IM, Stanley BG, Korzus E, Fiacco TA, Binder DK, Wilson EH.

PLoS Pathog. 2016 Jun 9;12(6):e1005643. doi: 10.1371/journal.ppat.1005643. eCollection 2016 Jun.

10.

Antitumor activity of a polypyridyl chelating ligand: in vitro and in vivo inhibition of glioma.

David CN, Frias ES, Elix CC, McGovern KE, Walker AM, Eichler JF, Wilson EH.

ASN Neuro. 2015 Jan-Feb;7(1). doi: 10.1177/1759091415572365.

11.

From phenomenology to neurophysiological understanding of hallucinations in children and adolescents.

Jardri R, Bartels-Velthuis AA, Debbané M, Jenner JA, Kelleher I, Dauvilliers Y, Plazzi G, Demeulemeester M, David CN, Rapoport J, Dobbelaere D, Escher S, Fernyhough C.

Schizophr Bull. 2014 Jul;40 Suppl 4:S221-32. doi: 10.1093/schbul/sbu029. Review.

12.

Innexin gap junctions in nerve cells coordinate spontaneous contractile behavior in Hydra polyps.

Takaku Y, Hwang JS, Wolf A, Böttger A, Shimizu H, David CN, Gojobori T.

Sci Rep. 2014 Jan 7;4:3573. doi: 10.1038/srep03573. Erratum in: Sci Rep. 2014;4:4009.

13.

Selective cavitand-mediated endocytosis of targeted imaging agents into live cells.

Ghang YJ, Schramm MP, Zhang F, Acey RA, David CN, Wilson EH, Wang Y, Cheng Q, Hooley RJ.

J Am Chem Soc. 2013 May 15;135(19):7090-3. doi: 10.1021/ja401273g. Epub 2013 Apr 30.

14.

Treatments in context: transcranial direct current brain stimulation as a potential treatment in pediatric psychosis.

David CN, Rapoport JL, Gogtay N.

Expert Rev Neurother. 2013 Apr;13(4):447-58. doi: 10.1586/ern.13.29. Review.

15.

The medial prefrontal cortex is critical for memory retrieval and resolving interference.

Peters GJ, David CN, Marcus MD, Smith DM.

Learn Mem. 2013 Mar 19;20(4):201-9. doi: 10.1101/lm.029249.112.

16.

Horizontal gene transfer contributed to the evolution of extracellular surface structures: the freshwater polyp Hydra is covered by a complex fibrous cuticle containing glycosaminoglycans and proteins of the PPOD and SWT (sweet tooth) families.

Böttger A, Doxey AC, Hess MW, Pfaller K, Salvenmoser W, Deutzmann R, Geissner A, Pauly B, Altstätter J, Münder S, Heim A, Gabius HJ, McConkey BJ, David CN.

PLoS One. 2012;7(12):e52278. doi: 10.1371/journal.pone.0052278. Epub 2012 Dec 27.

17.

Interstitial stem cells in Hydra: multipotency and decision-making.

David CN.

Int J Dev Biol. 2012;56(6-8):489-97. Review.

18.

In vivo imaging of basement membrane movement: ECM patterning shapes Hydra polyps.

Aufschnaiter R, Zamir EA, Little CD, Özbek S, Münder S, David CN, Li L, Sarras MP Jr, Zhang X.

J Cell Sci. 2011 Dec 1;124(Pt 23):4027-38. doi: 10.1242/jcs.087239.

19.

Childhood onset schizophrenia: high rate of visual hallucinations.

David CN, Greenstein D, Clasen L, Gochman P, Miller R, Tossell JW, Mattai AA, Gogtay N, Rapoport JL.

J Am Acad Child Adolesc Psychiatry. 2011 Jul;50(7):681-686.e3. doi: 10.1016/j.jaac.2011.03.020. Epub 2011 Jun 11.

20.

A genomic view of 500 million years of cnidarian evolution.

Steele RE, David CN, Technau U.

Trends Genet. 2011 Jan;27(1):7-13. doi: 10.1016/j.tig.2010.10.002. Epub 2010 Nov 1. Review.

21.

Nematogalectin, a nematocyst protein with GlyXY and galectin domains, demonstrates nematocyte-specific alternative splicing in Hydra.

Hwang JS, Takaku Y, Momose T, Adamczyk P, Özbek S, Ikeo K, Khalturin K, Hemmrich G, Bosch TC, Holstein TW, David CN, Gojobori T.

Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18539-44. doi: 10.1073/pnas.1003256107. Epub 2010 Oct 11.

22.

The molecular cell death machinery in the simple cnidarian Hydra includes an expanded caspase family and pro- and anti-apoptotic Bcl-2 proteins.

Lasi M, Pauly B, Schmidt N, Cikala M, Stiening B, Käsbauer T, Zenner G, Popp T, Wagner A, Knapp RT, Huber AH, Grunert M, Söding J, David CN, Böttger A.

Cell Res. 2010 Jul;20(7):812-25. doi: 10.1038/cr.2010.66. Epub 2010 May 18.

PMID:
20479784
23.

The dynamic genome of Hydra.

Chapman JA, Kirkness EF, Simakov O, Hampson SE, Mitros T, Weinmaier T, Rattei T, Balasubramanian PG, Borman J, Busam D, Disbennett K, Pfannkoch C, Sumin N, Sutton GG, Viswanathan LD, Walenz B, Goodstein DM, Hellsten U, Kawashima T, Prochnik SE, Putnam NH, Shu S, Blumberg B, Dana CE, Gee L, Kibler DF, Law L, Lindgens D, Martinez DE, Peng J, Wigge PA, Bertulat B, Guder C, Nakamura Y, Ozbek S, Watanabe H, Khalturin K, Hemmrich G, Franke A, Augustin R, Fraune S, Hayakawa E, Hayakawa S, Hirose M, Hwang JS, Ikeo K, Nishimiya-Fujisawa C, Ogura A, Takahashi T, Steinmetz PR, Zhang X, Aufschnaiter R, Eder MK, Gorny AK, Salvenmoser W, Heimberg AM, Wheeler BM, Peterson KJ, Böttger A, Tischler P, Wolf A, Gojobori T, Remington KA, Strausberg RL, Venter JC, Technau U, Hobmayer B, Bosch TC, Holstein TW, Fujisawa T, Bode HR, David CN, Rokhsar DS, Steele RE.

Nature. 2010 Mar 25;464(7288):592-6. doi: 10.1038/nature08830. Epub 2010 Mar 14.

24.

Apoptosis in pre-Bilaterians: Hydra as a model.

Lasi M, David CN, Böttger A.

Apoptosis. 2010 Mar;15(3):269-78. doi: 10.1007/s10495-009-0442-7. Review.

PMID:
20041301
25.

The BCL-2-like protein CED-9 of C. elegans promotes FZO-1/Mfn1,2- and EAT-3/Opa1-dependent mitochondrial fusion.

Rolland SG, Lu Y, David CN, Conradt B.

J Cell Biol. 2009 Aug 24;186(4):525-40. doi: 10.1083/jcb.200905070.

26.

Further characterization of the PW peptide family that inhibits neuron differentiation in Hydra.

Takahashi T, Koizumi O, Hayakawa E, Minobe S, Suetsugu R, Kobayakawa Y, Bosch TC, David CN, Fujisawa T.

Dev Genes Evol. 2009 Mar;219(3):119-29. doi: 10.1007/s00427-009-0272-1. Epub 2009 Jan 30.

PMID:
19184097
27.

Evolution of complex structures: minicollagens shape the cnidarian nematocyst.

David CN, Ozbek S, Adamczyk P, Meier S, Pauly B, Chapman J, Hwang JS, Gojobori T, Holstein TW.

Trends Genet. 2008 Sep;24(9):431-8. doi: 10.1016/j.tig.2008.07.001. Epub 2008 Aug 3.

PMID:
18676050
28.

Cilium evolution: identification of a novel protein, nematocilin, in the mechanosensory cilium of Hydra nematocytes.

Hwang JS, Takaku Y, Chapman J, Ikeo K, David CN, Gojobori T.

Mol Biol Evol. 2008 Sep;25(9):2009-17. doi: 10.1093/molbev/msn154. Epub 2008 Jul 17.

PMID:
18635678
29.

The evolutionary emergence of cell type-specific genes inferred from the gene expression analysis of Hydra.

Hwang JS, Ohyanagi H, Hayakawa S, Osato N, Nishimiya-Fujisawa C, Ikeo K, David CN, Fujisawa T, Gojobori T.

Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14735-40. Epub 2007 Aug 31.

30.

Proteomic screen in the simple metazoan Hydra identifies 14-3-3 binding proteins implicated in cellular metabolism, cytoskeletal organisation and Ca2+ signalling.

Pauly B, Lasi M, MacKintosh C, Morrice N, Imhof A, Regula J, Rudd S, David CN, Böttger A.

BMC Cell Biol. 2007 Jul 25;8:31.

31.

Continuous molecular evolution of protein-domain structures by single amino acid changes.

Meier S, Jensen PR, David CN, Chapman J, Holstein TW, Grzesiek S, Ozbek S.

Curr Biol. 2007 Jan 23;17(2):173-8.

32.

The Notch signaling pathway in the cnidarian Hydra.

Käsbauer T, Towb P, Alexandrova O, David CN, Dall'armi E, Staudigl A, Stiening B, Böttger A.

Dev Biol. 2007 Mar 1;303(1):376-90. Epub 2006 Nov 17.

33.

Genetic screen for signal peptides in Hydra reveals novel secreted proteins and evidence for non-classical protein secretion.

Böttger A, Strasser D, Alexandrova O, Levin A, Fischer S, Lasi M, Rudd S, David CN.

Eur J Cell Biol. 2006 Sep;85(9-10):1107-17. Epub 2006 Jun 30.

PMID:
16814424
34.

Hydra and the evolution of apoptosis.

David CN, Schmidt N, Schade M, Pauly B, Alexandrova O, Böttger A.

Integr Comp Biol. 2005 Aug;45(4):631-8. doi: 10.1093/icb/45.4.631.

PMID:
21676810
35.

Oogenesis in Hydra: nurse cells transfer cytoplasm directly to the growing oocyte.

Alexandrova O, Schade M, Böttger A, David CN.

Dev Biol. 2005 May 1;281(1):91-101.

36.

Role of real-time myocardial contrast echocardiography in the assessment of viability after acute myocardial infarction and angioplasty.

Almeida AG, David CN, Gabriel HM, da Costa JM, Pacheco M, Sargento L, Rodrigues S, Ribeiro M, da Cunha JC, Vagueiro MC.

Rev Port Cardiol. 2004 Oct;23(10):1277-87. English, Portuguese.

PMID:
15641293
37.

Evolution of gap junctions: the missing link?

Alexopoulos H, Böttger A, Fischer S, Levin A, Wolf A, Fujisawa T, Hayakawa S, Gojobori T, Davies JA, David CN, Bacon JP.

Curr Biol. 2004 Oct 26;14(20):R879-80. No abstract available.

38.

The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity.

Cikala M, Alexandrova O, David CN, Pröschel M, Stiening B, Cramer P, Böttger A.

BMC Cell Biol. 2004 Jun 11;5:26.

39.

Control of planula migration by LWamide and RFamide neuropeptides in Hydractinia echinata.

Katsukura Y, Ando H, David CN, Grimmelikhuijzen CJ, Sugiyama T.

J Exp Biol. 2004 May;207(Pt 11):1803-10.

40.

Replication labeling patterns and chromosome territories typical of mammalian nuclei are conserved in the early metazoan Hydra.

Alexandrova O, Solovei I, Cremer T, David CN.

Chromosoma. 2003 Dec;112(4):190-200. Epub 2003 Nov 13.

PMID:
14615892
41.

Inhibition of metamorphosis by RFamide neuropeptides in planula larvae of Hydractinia echinata.

Katsukura Y, David CN, Grimmelikhuijzen CJ, Sugiyama T.

Dev Genes Evol. 2003 Dec;213(12):579-86. Epub 2003 Oct 30.

PMID:
14586653
42.

Molecular cloning and cellular distribution of two 14-3-3 isoforms from Hydra: 14-3-3 proteins respond to starvation and bind to phosphorylated targets.

Pauly B, Stiening B, Schade M, Alexandrova O, Zoubek R, David CN, Böttger A.

Exp Cell Res. 2003 Apr 15;285(1):15-26.

PMID:
12681283
43.

Cloning and characterisation of PKB and PRK homologs from Hydra and the evolution of the protein kinase family.

Herold M, Cikala M, MacWilliams H, David CN, Böttger A.

Dev Genes Evol. 2002 Dec;212(11):513-9. Epub 2002 Sep 18.

PMID:
12459919
44.

GFP expression in Hydra: lessons from the particle gun.

Böttger A, Alexandrova O, Cikala M, Schade M, Herold M, David CN.

Dev Genes Evol. 2002 Jul;212(6):302-5.

PMID:
12211170
45.

Poly-gamma-glutamate synthesis during formation of nematocyst capsules in Hydra.

Szczepanek S, Cikala M, David CN.

J Cell Sci. 2002 Feb 15;115(Pt 4):745-51.

46.

A switch in disulfide linkage during minicollagen assembly in Hydra nematocysts.

Engel U, Pertz O, Fauser C, Engel J, David CN, Holstein TW.

EMBO J. 2001 Jun 15;20(12):3063-73.

47.

Identification of caspases and apoptosis in the simple metazoan Hydra.

Cikala M, Wilm B, Hobmayer E, Böttger A, David CN.

Curr Biol. 1999 Sep 9;9(17):959-62.

48.

Spinalin, a new glycine- and histidine-rich protein in spines of Hydra nematocysts.

Koch AW, Holstein TW, Mala C, Kurz E, Engel J, David CN.

J Cell Sci. 1998 Jun;111 ( Pt 11):1545-54.

49.
50.

Systematic isolation of peptide signal molecules regulating development in hydra: LWamide and PW families.

Takahashi T, Muneoka Y, Lohmann J, Lopez de Haro MS, Solleder G, Bosch TC, David CN, Bode HR, Koizumi O, Shimizu H, Hatta M, Fujisawa T, Sugiyama T.

Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1241-6.

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