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Items: 1 to 50 of 869

1.

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study.

BIRTH-GENE (BIG) Study Working Group, Huang T, Wang T, Zheng Y, Ellervik C, Li X, Gao M, Fang Z, Chai JF, Ahluwalia TVS, Wang Y, Voortman T, Noordam R, Frazier-Wood A, Scholz M, Sonestedt E, Akiyama M, Dorajoo R, Zhou A, Kilpeläinen TO, Kleber ME, Crozier SR, Godfrey KM, Lemaitre R, Felix JF, Shi Y, Gupta P, Khor CC, Lehtimäki T, Wang CA, Tiesler CMT, Thiering E, Standl M, Rzehak P, Marouli E, He M, Lecoeur C, Corella D, Lai CQ, Moreno LA, Pitkänen N, Boreham CA, Zhang T, Saw SM, Ridker PM, Graff M, van Rooij FJA, Uitterlinden AG, Hofman A, van Heemst D, Rosendaal FR, de Mutsert R, Burkhardt R, Schulz CA, Ericson U, Kamatani Y, Yuan JM, Power C, Hansen T, Sørensen TIA, Tjønneland A, Overvad K, Delgado G, Cooper C, Djousse L, Rivadeneira F, Jameson K, Zhao W, Liu J, Lee NR, Raitakari O, Kähönen M, Viikari J, Grote V, Langhendries JP, Koletzko B, Escribano J, Verduci E, Dedoussis G, Yu C, Tham YC, Lim B, Lim SH, Froguel P, Balkau B, Fink NR, Vinding RK, Sevelsted A, Bisgaard H, Coltell O, Dallongeville J, Gottrand F, Pahkala K, Niinikoski H, Hyppönen E, Pedersen O, März W, Inskip H, Jaddoe VWV, Dennison E, Wong TY, Sabanayagam C, Tai ES, Mohlke KL, Mackey DA, Gruszfeld D, Deloukas P, Tucker KL, Fumeron F, Bønnelykke K, Rossing P, Estruch R, Ordovas JM, Arnett DK, Meirhaeghe A, Amouyel P, Cheng CY, Sim X, Teo YY, van Dam RM, Koh WP, Orho-Melander M, Loeffler M, Kubo M, Thiery J, Mook-Kanamori DO, Mozaffarian D, Psaty BM, Franco OH, Wu T, North KE, Davey Smith G, Chavarro JE, Chasman DI, Qi L.

JAMA Netw Open. 2019 Sep 4;2(9):e1910915. doi: 10.1001/jamanetworkopen.2019.10915.

PMID:
31539074
2.

Multivariable two-sample Mendelian randomization estimates of the effects of intelligence and education on health.

Davies NM, Hill WD, Anderson EL, Sanderson E, Deary IJ, Davey Smith G.

Elife. 2019 Sep 17;8. pii: e43990. doi: 10.7554/eLife.43990.

3.

A rare mutation in SMAD9 associated with high bone mass identifies the SMAD-dependent BMP signalling pathway as a potential anabolic target for osteoporosis.

Gregson CL, Bergen D, Leo P, Sessions RB, Wheeler L, Hartley A, Youlten S, Croucher PI, McInerney-Leo AM, Fraser W, Tang JCY, Anderson L, Marshall M, Sergot L, Paternoster L, Davey-Smith G; AOGC Consortium, Brown MA, Hammond C, Kemp JP, Tobias JH, Duncan EL.

J Bone Miner Res. 2019 Sep 16. doi: 10.1002/jbmr.3875. [Epub ahead of print]

PMID:
31525280
4.

Response to 'Does smoking or alcohol cause early vascular damage in teenage years?'

Charakida M, Georgiopoulos G, Dangardt F, Chiesa ST, Hughes AD, Rapala A, Davey Smith G, Lawlor D, Finer N, Deanfield JE.

Eur Heart J. 2019 Sep 11. pii: ehz608. doi: 10.1093/eurheartj/ehz608. [Epub ahead of print] No abstract available.

PMID:
31511879
5.

Identifying and Validating New Drug Targets for Stroke and Beyond.

Plump A, Davey Smith G.

Circulation. 2019 Sep 9;140(10):831-835. doi: 10.1161/CIRCULATIONAHA.119.042005. Epub 2019 Sep 3. No abstract available.

PMID:
31479321
6.

Using the MR-Base platform to investigate risk factors and drug targets for thousands of phenotypes.

Walker VM, Davies NM, Hemani G, Zheng J, Haycock PC, Gaunt TR, Davey Smith G, Martin RM.

Wellcome Open Res. 2019 Jul 29;4:113. doi: 10.12688/wellcomeopenres.15334.1. eCollection 2019.

7.

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals.

Deelen J, Kettunen J, Fischer K, van der Spek A, Trompet S, Kastenmüller G, Boyd A, Zierer J, van den Akker EB, Ala-Korpela M, Amin N, Demirkan A, Ghanbari M, van Heemst D, Ikram MA, van Klinken JB, Mooijaart SP, Peters A, Salomaa V, Sattar N, Spector TD, Tiemeier H, Verhoeven A, Waldenberger M, Würtz P, Davey Smith G, Metspalu A, Perola M, Menni C, Geleijnse JM, Drenos F, Beekman M, Jukema JW, van Duijn CM, Slagboom PE.

Nat Commun. 2019 Aug 20;10(1):3346. doi: 10.1038/s41467-019-11311-9.

8.

Variation of all-cause and cause-specific mortality with body mass index in one million Swedish parent-son pairs: An instrumental variable analysis.

Wade KH, Carslake D, Tynelius P, Davey Smith G, Martin RM.

PLoS Med. 2019 Aug 9;16(8):e1002868. doi: 10.1371/journal.pmed.1002868. eCollection 2019 Aug.

9.

Appraising the role of previously reported risk factors in epithelial ovarian cancer risk: A Mendelian randomization analysis.

Yarmolinsky J, Relton CL, Lophatananon A, Muir K, Menon U, Gentry-Maharaj A, Walther A, Zheng J, Fasching P, Zheng W, Yin Ling W, Park SK, Kim BG, Choi JY, Park B, Davey Smith G, Martin RM, Lewis SJ.

PLoS Med. 2019 Aug 7;16(8):e1002893. doi: 10.1371/journal.pmed.1002893. eCollection 2019 Aug.

10.

Correction to: Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?

Lawson DJ, Davies NM, Haworth S, Ashraf B, Howe L, Crawford A, Hemani G, Davey Smith G, Timpson NJ.

Hum Genet. 2019 Jul 30. doi: 10.1007/s00439-019-02051-3. [Epub ahead of print]

PMID:
31363835
11.

Masked hypertension and submaximal exercise blood pressure among adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC).

Huang Z, Sharman JE, Fonseca R, Park C, Chaturvedi N, Davey Smith G, Howe LD, Lawlor DA, Hughes AD, Schultz MG.

Scand J Med Sci Sports. 2019 Jul 28. doi: 10.1111/sms.13525. [Epub ahead of print]

PMID:
31353626
12.

How humans can contribute to Mendelian randomization analyses.

Burgess S, Davey Smith G.

Int J Epidemiol. 2019 Jun 1;48(3):661-664. doi: 10.1093/ije/dyz152. No abstract available.

PMID:
31326987
13.

Morning plasma cortisol as a cardiovascular risk factor: findings from prospective cohort and Mendelian randomization studies.

Crawford AA, Söderberg S, Kirschbaum C, Murphy L, Eliasson M, Ebrahim S, Davey Smith G, Olsson T, Sattar N, Lawlor DA, Timpson NJ, Reynolds RM, Walker BR.

Eur J Endocrinol. 2019 Jul 1. pii: EJE-19-0161.R1. doi: 10.1530/EJE-19-0161. [Epub ahead of print]

14.

Birthweight in offspring and cardiovascular mortality in their parents, aunts and uncles: a family-based cohort study of 1.35 million births.

Shaikh F, Kjølllesdal MK, Carslake D, Stoltenberg C, Davey Smith G, Næss Ø.

Int J Epidemiol. 2019 Jul 20. pii: dyz156. doi: 10.1093/ije/dyz156. [Epub ahead of print]

PMID:
31325357
15.

A phenome-wide Mendelian randomization study of pancreatic cancer using summary genetic data.

Langdon RJ, Richmond RC, Hemani G, Zheng J, Wade KH, Carreras-Torres R, Johannson M, Brennan P, Wootton RE, Munafo MR, Davey Smith G, Relton CL, Vincent EE, Martin RM, Haycock P.

Cancer Epidemiol Biomarkers Prev. 2019 Jul 17. pii: cebp.0036.2019. doi: 10.1158/1055-9965.EPI-19-0036. [Epub ahead of print]

PMID:
31315910
16.

Commentary: Orienting causal relationships between two phenotypes using bidirectional Mendelian randomization.

Richmond RC, Davey Smith G.

Int J Epidemiol. 2019 Jun 1;48(3):907-911. doi: 10.1093/ije/dyz149. No abstract available.

PMID:
31298278
17.

Mendelian randomisation analysis of the effect of educational attainment and cognitive ability on smoking behaviour.

Sanderson E, Davey Smith G, Bowden J, Munafò MR.

Nat Commun. 2019 Jul 3;10(1):2949. doi: 10.1038/s41467-019-10679-y.

18.

An integrative approach to detect epigenetic mechanisms that putatively mediate the influence of lifestyle exposures on disease susceptibility.

Richardson TG, Richmond RC, North TL, Hemani G, Davey Smith G, Sharp GC, Relton CL.

Int J Epidemiol. 2019 Jun 1;48(3):887-898. doi: 10.1093/ije/dyz119.

19.

Comment on the Relationship Between Common Variant Schizophrenia Liability and Number of Offspring in the UK Biobank.

Lawn RB, Sallis HM, Taylor AE, Wootton RE, Davey Smith G, Davies NM, Hemani G, Fraser A, Penton-Voak IS, Munafò MR.

Am J Psychiatry. 2019 Jul 1;176(7):573-574. doi: 10.1176/appi.ajp.2019.19010071. No abstract available.

PMID:
31256616
20.

Identifying Novel Types of Irritability Using a Developmental Genetic Approach.

Riglin L, Eyre O, Thapar AK, Stringaris A, Leibenluft E, Pine DS, Tilling K, Davey Smith G, O'Donovan MC, Thapar A.

Am J Psychiatry. 2019 Aug 1;176(8):635-642. doi: 10.1176/appi.ajp.2019.18101134. Epub 2019 Jul 1.

PMID:
31256611
21.

Interleukin-18 as a drug repositioning opportunity for inflammatory bowel disease: A Mendelian randomization study.

Mokry LE, Zhou S, Guo C, Scott RA, Devey L, Langenberg C, Wareham N, Waterworth D, Cardon L, Sanseau P, Davey Smith G, Richards JB.

Sci Rep. 2019 Jun 28;9(1):9386. doi: 10.1038/s41598-019-45747-2.

22.

Associations of mortality with own blood pressure using son's blood pressure as an instrumental variable.

Carslake D, Fraser A, May MT, Palmer T, Silventoinen K, Tynelius P, Lawlor DA, Davey Smith G.

Sci Rep. 2019 Jun 20;9(1):8986. doi: 10.1038/s41598-019-45391-w.

23.

Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures.

Zheng J, Maerz W, Gergei I, Kleber M, Drechsler C, Wanner C, Brandenburg V, Reppe S, Gautvik KM, Medina-Gomez C, Shevroja E, Gilly A, Park YC, Dedoussis G, Zeggini E, Lorentzon M, Henning P, Lerner UH, Nilsson KH, Movérare-Skrtic S, Baird D, Elsworth B, Falk L, Groom A, Capellini TD, Grundberg E, Nethander M, Ohlsson C, Davey Smith G, Tobias JH.

J Bone Miner Res. 2019 Jun 6. doi: 10.1002/jbmr.3803. [Epub ahead of print]

PMID:
31170332
24.

Association between fat mass through adolescence and arterial stiffness: a population-based study from The Avon Longitudinal Study of Parents and Children.

Dangardt F, Charakida M, Georgiopoulos G, Chiesa ST, Rapala A, Wade KH, Hughes AD, Timpson NJ, Pateras K, Finer N, Sattar N, Davey Smith G, Lawlor DA, Deanfield JE.

Lancet Child Adolesc Health. 2019 Jul;3(7):474-481. doi: 10.1016/S2352-4642(19)30105-1. Epub 2019 May 21.

25.

Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study.

Carter AR, Gill D, Davies NM, Taylor AE, Tillmann T, Vaucher J, Wootton RE, Munafò MR, Hemani G, Malik R, Seshadri S, Woo D, Burgess S, Davey Smith G, Holmes MV, Tzoulaki I, Howe LD, Dehghan A.

BMJ. 2019 May 22;365:l1855. doi: 10.1136/bmj.l1855.

26.

A third of nonfasting plasma cholesterol is in remnant lipoproteins: Lipoprotein subclass profiling in 9293 individuals.

Balling M, Langsted A, Afzal S, Varbo A, Davey Smith G, Nordestgaard BG.

Atherosclerosis. 2019 Jul;286:97-104. doi: 10.1016/j.atherosclerosis.2019.05.011. Epub 2019 May 9.

PMID:
31108411
27.

Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle.

Taylor DL, Jackson AU, Narisu N, Hemani G, Erdos MR, Chines PS, Swift A, Idol J, Didion JP, Welch RP, Kinnunen L, Saramies J, Lakka TA, Laakso M, Tuomilehto J, Parker SCJ, Koistinen HA, Davey Smith G, Boehnke M, Scott LJ, Birney E, Collins FS.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):10883-10888. doi: 10.1073/pnas.1814263116. Epub 2019 May 10.

28.

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease.

Ward-Caviness CK, de Vries PS, Wiggins KL, Huffman JE, Yanek LR, Bielak LF, Giulianini F, Guo X, Kleber ME, Kacprowski T, Groß S, Petersman A, Davey Smith G, Hartwig FP, Bowden J, Hemani G, Müller-Nuraysid M, Strauch K, Koenig W, Waldenberger M, Meitinger T, Pankratz N, Boerwinkle E, Tang W, Fu YP, Johnson AD, Song C, de Maat MPM, Uitterlinden AG, Franco OH, Brody JA, McKnight B, Chen YI, Psaty BM, Mathias RA, Becker DM, Peyser PA, Smith JA, Bielinski SJ, Ridker PM, Taylor KD, Yao J, Tracy R, Delgado G, Trompet S, Sattar N, Jukema JW, Becker LC, Kardia SLR, Rotter JI, März W, Dörr M, Chasman DI, Dehghan A, O'Donnell CJ, Smith NL, Peters A, Morrison AC.

PLoS One. 2019 May 10;14(5):e0216222. doi: 10.1371/journal.pone.0216222. eCollection 2019.

29.

The effect of smoking intensity on all-cause and cause-specific mortality-a Mendelian randomization analysis.

Vie GÅ, Wootton RE, Bjørngaard JH, Åsvold BO, Taylor AE, Gabrielsen ME, Davey Smith G, Romundstad PR, Munafò MR.

Int J Epidemiol. 2019 May 10. pii: dyz081. doi: 10.1093/ije/dyz081. [Epub ahead of print]

PMID:
31074779
30.

Urbanization and Altitude Are Associated with Low Kidney Function in Peru.

Carrillo-Larco RM, Miranda JJ, Gilman RH, Narvaez-Guerra O, Herrera-Enriquez K, Medina-Lezama J, Smeeth L, Checkley W, Bernabe-Ortiz A; CRONICAS Cohort Study Group.

High Alt Med Biol. 2019 Jun;20(2):133-140. doi: 10.1089/ham.2018.0106. Epub 2019 May 7.

31.

Polygenic risk scores for Alzheimer's disease, and academic achievement, cognitive and behavioural measures in children from the general population.

Korologou-Linden R, Anderson EL, Jones HJ, Davey Smith G, Howe LD, Stergiakouli E.

Int J Epidemiol. 2019 May 5. pii: dyz080. doi: 10.1093/ije/dyz080. [Epub ahead of print]

PMID:
31056667
32.

Gestational route to healthy birth (GaRBH): protocol for an Indian prospective cohort study.

Gupta V, Saxena R, Walia GK, Agarwal T, Vats H, Dunn W, Relton C, Sovio U, Papageorghiou A, Davey Smith G, Khadgawat R, Sachdeva MP.

BMJ Open. 2019 May 1;9(4):e025395. doi: 10.1136/bmjopen-2018-025395.

33.

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner NW, Qiao Z, Moen GH, Vaudel M, Marsit CJ, Chen J, Nodzenski M, Schnurr TM, Zafarmand MH, Bradfield JP, Grarup N, Kooijman MN, Li-Gao R, Geller F, Ahluwalia TS, Paternoster L, Rueedi R, Huikari V, Hottenga JJ, Lyytikäinen LP, Cavadino A, Metrustry S, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Vilor-Tejedor N, Joshi PK, Painter JN, Ntalla I, Myhre R, Pitkänen N, van Leeuwen EM, Joro R, Lagou V, Richmond RC, Espinosa A, Barton SJ, Inskip HM, Holloway JW, Santa-Marina L, Estivill X, Ang W, Marsh JA, Reichetzeder C, Marullo L, Hocher B, Lunetta KL, Murabito JM, Relton CL, Kogevinas M, Chatzi L, Allard C, Bouchard L, Hivert MF, Zhang G, Muglia LJ, Heikkinen J; EGG Consortium, Morgen CS, van Kampen AHC, van Schaik BDC, Mentch FD, Langenberg C, Luan J, Scott RA, Zhao JH, Hemani G, Ring SM, Bennett AJ, Gaulton KJ, Fernandez-Tajes J, van Zuydam NR, Medina-Gomez C, de Haan HG, Rosendaal FR, Kutalik Z, Marques-Vidal P, Das S, Willemsen G, Mbarek H, Müller-Nurasyid M, Standl M, Appel EVR, Fonvig CE, Trier C, van Beijsterveldt CEM, Murcia M, Bustamante M, Bonas-Guarch S, Hougaard DM, Mercader JM, Linneberg A, Schraut KE, Lind PA, Medland SE, Shields BM, Knight BA, Chai JF, Panoutsopoulou K, Bartels M, Sánchez F, Stokholm J, Torrents D, Vinding RK, Willems SM, Atalay M, Chawes BL, Kovacs P, Prokopenko I, Tuke MA, Yaghootkar H, Ruth KS, Jones SE, Loh PR, Murray A, Weedon MN, Tönjes A, Stumvoll M, Michaelsen KF, Eloranta AM, Lakka TA, van Duijn CM, Kiess W, Körner A, Niinikoski H, Pahkala K, Raitakari OT, Jacobsson B, Zeggini E, Dedoussis GV, Teo YY, Saw SM, Montgomery GW, Campbell H, Wilson JF, Vrijkotte TGM, Vrijheid M, de Geus EJCN, Hayes MG, Kadarmideen HN, Holm JC, Beilin LJ, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widén EE, Hattersley AT, Spector TD, Kähönen M, Viikari JS, Lehtimäki T, Boomsma DI, Sebert S, Vollenweider P, Sørensen TIA, Bisgaard H, Bønnelykke K, Murray JC, Melbye M, Nohr EA, Mook-Kanamori DO, Rivadeneira F, Hofman A, Felix JF, Jaddoe VWV, Hansen T, Pisinger C, Vaag AA, Pedersen O, Uitterlinden AG, Järvelin MR, Power C, Hyppönen E, Scholtens DM, Lowe WL Jr, Davey Smith G, Timpson NJ, Morris AP, Wareham NJ, Hakonarson H, Grant SFA, Frayling TM, Lawlor DA, Njølstad PR, Johansson S, Ong KK, McCarthy MI, Perry JRB, Evans DM, Freathy RM.

Nat Genet. 2019 May;51(5):804-814. doi: 10.1038/s41588-019-0403-1. Epub 2019 May 1.

PMID:
31043758
34.

Association of Maternal Neurodevelopmental Risk Alleles With Early-Life Exposures.

Leppert B, Havdahl A, Riglin L, Jones HJ, Zheng J, Davey Smith G, Tilling K, Thapar A, Reichborn-Kjennerud T, Stergiakouli E.

JAMA Psychiatry. 2019 May 1. doi: 10.1001/jamapsychiatry.2019.0774. [Epub ahead of print]

35.

Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?

Lawson DJ, Davies NM, Haworth S, Ashraf B, Howe L, Crawford A, Hemani G, Davey Smith G, Timpson NJ.

Hum Genet. 2019 Apr 27. doi: 10.1007/s00439-019-02014-8. [Epub ahead of print] Erratum in: Hum Genet. 2019 Jul 30;:.

PMID:
31030318
36.

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, Breton CV, Allard C, Just AC, Bakulski KM, Holloway JW, Everson TM, Xu CJ, Huang RC, van der Plaat DA, Wielscher M, Merid SK, Ullemar V, Rezwan FI, Lahti J, van Dongen J, Langie SAS, Richardson TG, Magnus MC, Nohr EA, Xu Z, Duijts L, Zhao S, Zhang W, Plusquin M, DeMeo DL, Solomon O, Heimovaara JH, Jima DD, Gao L, Bustamante M, Perron P, Wright RO, Hertz-Picciotto I, Zhang H, Karagas MR, Gehring U, Marsit CJ, Beilin LJ, Vonk JM, Jarvelin MR, Bergström A, Örtqvist AK, Ewart S, Villa PM, Moore SE, Willemsen G, Standaert ARL, Håberg SE, Sørensen TIA, Taylor JA, Räikkönen K, Yang IV, Kechris K, Nawrot TS, Silver MJ, Gong YY, Richiardi L, Kogevinas M, Litonjua AA, Eskenazi B, Huen K, Mbarek H, Maguire RL, Dwyer T, Vrijheid M, Bouchard L, Baccarelli AA, Croen LA, Karmaus W, Anderson D, de Vries M, Sebert S, Kere J, Karlsson R, Arshad SH, Hämäläinen E, Routledge MN, Boomsma DI, Feinberg AP, Newschaffer CJ, Govarts E, Moisse M, Fallin MD, Melén E, Prentice AM, Kajantie E, Almqvist C, Oken E, Dabelea D, Boezen HM, Melton PE, Wright RJ, Koppelman GH, Trevisi L, Hivert MF, Sunyer J, Munthe-Kaas MC, Murphy SK, Corpeleijn E, Wiemels J, Holland N, Herceg Z, Binder EB, Davey Smith G, Jaddoe VWV, Lie RT, Nystad W, London SJ, Lawlor DA, Relton CL, Snieder H, Felix JF.

Nat Commun. 2019 Apr 23;10(1):1893. doi: 10.1038/s41467-019-09671-3.

37.

Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China.

Millwood IY, Walters RG, Mei XW, Guo Y, Yang L, Bian Z, Bennett DA, Chen Y, Dong C, Hu R, Zhou G, Yu B, Jia W, Parish S, Clarke R, Davey Smith G, Collins R, Holmes MV, Li L, Peto R, Chen Z; China Kadoorie Biobank Collaborative Group.

Lancet. 2019 May 4;393(10183):1831-1842. doi: 10.1016/S0140-6736(18)31772-0. Epub 2019 Apr 4.

38.

Childhood neurodevelopmental difficulties and risk of adolescent depression: the role of irritability.

Eyre O, Hughes RA, Thapar AK, Leibenluft E, Stringaris A, Davey Smith G, Stergiakouli E, Collishaw S, Thapar A.

J Child Psychol Psychiatry. 2019 Aug;60(8):866-874. doi: 10.1111/jcpp.13053. Epub 2019 Mar 25.

PMID:
30908655
39.

RE: Prenatal smoke exposure, DNA methylation and a link between DRD1 and lung cancer.

Richmond RC, Suderman M, Langdon R, Relton CL, Davey Smith G.

Int J Epidemiol. 2019 Mar 21. pii: dyz036. doi: 10.1093/ije/dyz036. [Epub ahead of print] No abstract available.

PMID:
30903164
40.

Selection Bias When Estimating Average Treatment Effects Using One-sample Instrumental Variable Analysis.

Hughes RA, Davies NM, Davey Smith G, Tilling K.

Epidemiology. 2019 May;30(3):350-357. doi: 10.1097/EDE.0000000000000972.

PMID:
30896457
41.

A Metabolic Screen in Adolescents Reveals an Association Between Circulating Citrate and Cortical Bone Mineral Density.

Kemp JP, Sayers A, Fraser WD, Davey Smith G, Ala-Korpela M, Evans DM, Tobias JH.

J Bone Miner Res. 2019 Jul;34(7):1306-1313. doi: 10.1002/jbmr.3697. Epub 2019 Mar 18.

PMID:
30882941
42.

Combined Association of Body Mass Index and Alcohol Consumption With Biomarkers for Liver Injury and Incidence of Liver Disease: A Mendelian Randomization Study.

Carter AR, Borges MC, Benn M, Tybjærg-Hansen A, Davey Smith G, Nordestgaard BG, Lawlor DA.

JAMA Netw Open. 2019 Mar 1;2(3):e190305. doi: 10.1001/jamanetworkopen.2019.0305.

43.

An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome.

Richardson TG, Harrison S, Hemani G, Davey Smith G.

Elife. 2019 Mar 5;8. pii: e43657. doi: 10.7554/eLife.43657.

44.

Investigating causality in the association between vitamin D status and self-reported tiredness.

Havdahl A, Mitchell R, Paternoster L, Davey Smith G.

Sci Rep. 2019 Feb 27;9(1):2880. doi: 10.1038/s41598-019-39359-z.

45.

Identification of common genetic risk variants for autism spectrum disorder.

Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont AL, Goldstein JI, Hansen CS, Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman CM, Klei L, Maller J, Martin J, Martin AR, Moran JL, Nyegaard M, Nærland T, Palmer DS, Palotie A, Pedersen CB, Pedersen MG, dPoterba T, Poulsen JB, Pourcain BS, Qvist P, Rehnström K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos P, Saemundsen E, Sandin S, Satterstrom FK, Davey Smith G, Stefansson H, Steinberg S, Stevens CR, Sullivan PF, Turley P, Walters GB, Xu X; Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium; BUPGEN; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; 23andMe Research Team, Stefansson K, Geschwind DH, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, Børglum AD.

Nat Genet. 2019 Mar;51(3):431-444. doi: 10.1038/s41588-019-0344-8. Epub 2019 Feb 25.

46.

Conditioning on a Collider May Induce Spurious Associations: Do the Results of Gale et al. (2017) Support a Health-Protective Effect of Neuroticism in Population Subgroups?

Richardson TG, Davey Smith G, Munafò MR.

Psychol Sci. 2019 Apr;30(4):629-632. doi: 10.1177/0956797618774532. Epub 2019 Feb 22. No abstract available.

PMID:
30794476
47.

Searching for the causal effects of body mass index in over 300 000 participants in UK Biobank, using Mendelian randomization.

Millard LAC, Davies NM, Tilling K, Gaunt TR, Davey Smith G.

PLoS Genet. 2019 Feb 1;15(2):e1007951. doi: 10.1371/journal.pgen.1007951. eCollection 2019 Feb.

48.

Prioritizing putative influential genes in cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization.

Taylor K, Davey Smith G, Relton CL, Gaunt TR, Richardson TG.

Genome Med. 2019 Jan 31;11(1):6. doi: 10.1186/s13073-019-0613-2.

49.

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study.

Budu-Aggrey A, Brumpton B, Tyrrell J, Watkins S, Modalsli EH, Celis-Morales C, Ferguson LD, Vie GÅ, Palmer T, Fritsche LG, Løset M, Nielsen JB, Zhou W, Tsoi LC, Wood AR, Jones SE, Beaumont R, Saunes M, Romundstad PR, Siebert S, McInnes IB, Elder JT, Davey Smith G, Frayling TM, Åsvold BO, Brown SJ, Sattar N, Paternoster L.

PLoS Med. 2019 Jan 31;16(1):e1002739. doi: 10.1371/journal.pmed.1002739. eCollection 2019 Jan.

50.

Can Mendelian Randomization Shift into Reverse Gear?

Holmes MV, Davey Smith G.

Clin Chem. 2019 Mar;65(3):363-366. doi: 10.1373/clinchem.2018.296806. Epub 2019 Jan 28. No abstract available.

PMID:
30692117

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