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Items: 32

1.

Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response.

Lucas-Hourani M, Dauzonne D, Munier-Lehmann H, Khiar S, Nisole S, Dairou J, Helynck O, Afonso PV, Tangy F, Vidalain PO.

Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00383-17. doi: 10.1128/AAC.00383-17. Print 2017 Oct.

2.

Exploring the mechanism of inhibition of human telomerase by cysteine-reactive compounds.

Kellermann G, Dingli F, Masson V, Dauzonne D, Ségal-Bendirdjian E, Teulade-Fichou MP, Loew D, Bombard S.

FEBS Lett. 2017 Mar;591(6):863-874. doi: 10.1002/1873-3468.12589. Epub 2017 Mar 1.

3.

Metabolism of Flavone-8-acetic Acid in Mice.

Pham MH, Auzeil N, Regazzetti A, Scherman D, Seguin J, Mignet N, Dauzonne D, Chabot GG.

Anticancer Res. 2016 Aug;36(8):3889-98.

PMID:
27466491
4.

Not flavone-8-acetic acid (FAA) but its murine metabolite 6-OH-FAA exhibits remarkable antivascular activities in vitro.

Pham MH, Dauzonne D, Chabot GG.

Anticancer Drugs. 2016 Jun;27(5):398-406. doi: 10.1097/CAD.0000000000000341.

PMID:
26901071
5.

Respiratory syncytial virus infection in macaques is not suppressed by intranasal sprays of pyrimidine biosynthesis inhibitors.

Grandin C, Hourani ML, Janin YL, Dauzonne D, Munier-Lehmann H, Paturet A, Taborik F, Vabret A, Contamin H, Tangy F, Vidalain PO.

Antiviral Res. 2016 Jan;125:58-62. doi: 10.1016/j.antiviral.2015.11.006. Epub 2015 Nov 22.

PMID:
26593978
6.

Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity.

Lucas-Hourani M, Dauzonne D, Jorda P, Cousin G, Lupan A, Helynck O, Caignard G, Janvier G, André-Leroux G, Khiar S, Escriou N, Desprès P, Jacob Y, Munier-Lehmann H, Tangy F, Vidalain PO.

PLoS Pathog. 2013;9(10):e1003678. doi: 10.1371/journal.ppat.1003678. Epub 2013 Oct 3.

7.

p70S6 kinase is a target of the novel proteasome inhibitor 3,3'-diamino-4'-methoxyflavone during apoptosis in human myeloid tumor cells.

Piedfer M, Bouchet S, Tang R, Billard C, Dauzonne D, Bauvois B.

Biochim Biophys Acta. 2013 Jun;1833(6):1316-28. doi: 10.1016/j.bbamcr.2013.02.016. Epub 2013 Feb 26.

8.

In vitro and in vivo biological evaluation of new 4,5-disubstituted 1,2,3-triazoles as cis-constrained analogs of combretastatin A4.

Mur Blanch N, Chabot GG, Quentin L, Scherman D, Bourg S, Dauzonne D.

Eur J Med Chem. 2012 Aug;54:22-32. doi: 10.1016/j.ejmech.2012.04.017. Epub 2012 May 9.

9.

C5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development.

Ceccaldi A, Rajavelu A, Champion C, Rampon C, Jurkowska R, Jankevicius G, Sénamaud-Beaufort C, Ponger L, Gagey N, Ali HD, Tost J, Vriz S, Ros S, Dauzonne D, Jeltsch A, Guianvarc'h D, Arimondo PB.

Chembiochem. 2011 Jun 14;12(9):1337-45. doi: 10.1002/cbic.201100130. Epub 2011 Jun 1.

PMID:
21633996
10.

Aminopeptidase-N/CD13 is a potential proapoptotic target in human myeloid tumor cells.

Piedfer M, Dauzonne D, Tang R, N'Guyen J, Billard C, Bauvois B.

FASEB J. 2011 Aug;25(8):2831-42. doi: 10.1096/fj.11-181396. Epub 2011 May 12.

PMID:
21566207
11.

Contributions of the D-Ring to the activity of etoposide against human topoisomerase IIα: potential interactions with DNA in the ternary enzyme--drug--DNA complex.

Pitts SL, Jablonksy MJ, Duca M, Dauzonne D, Monneret C, Arimondo PB, Anklin C, Graves DE, Osheroff N.

Biochemistry. 2011 Jun 7;50(22):5058-66. doi: 10.1021/bi200531q. Epub 2011 May 13.

12.

Electrospray tandem mass spectrometry of beta-nitroalkenyl meso-tetraphenylporphyrins.

Silva EM, Domingues P, Tomé JP, Faustino MA, Neves MG, Tomé AC, Dauzonne D, Silva AM, Cavaleiro JA, Ferrer-Correia AJ, Domingues MR.

Eur J Mass Spectrom (Chichester). 2008;14(1):49-59. doi: 10.1255/ejms.908.

PMID:
18401045
13.

Characterization of monohydroxylated derivatives of the anticancer agent flavone-8-acetic acid by liquid chromatography with on-line UV and mass spectrometry.

Pham MH, Menet MC, Dugay A, Regazzetti A, Dauzonne D, Auzeil N, Scherman D, Chabot GG.

Rapid Commun Mass Spectrom. 2007;21(20):3373-86.

PMID:
17891752
14.

Identification of new flavone-8-acetic acid metabolites using mouse microsomes and comparison with human microsomes.

Pham MH, Auzeil N, Regazzetti A, Dauzonne D, Dugay A, Menet MC, Scherman D, Chabot GG.

Drug Metab Dispos. 2007 Nov;35(11):2023-34. Epub 2007 Jul 30.

PMID:
17664249
15.

Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides.

Duca M, Guianvarc'h D, Oussedik K, Halby L, Garbesi A, Dauzonne D, Monneret C, Osheroff N, Giovannangeli C, Arimondo PB.

Nucleic Acids Res. 2006 Apr 5;34(6):1900-11. Print 2006.

16.
17.

Triple helix-forming oligonucleotides conjugated to new inhibitors of topoisomerase II: synthesis and binding properties.

Duca M, Oussedik K, Ceccaldi A, Halby L, Guianvarc'h D, Dauzonne D, Monneret C, Sun JS, Arimondo PB.

Bioconjug Chem. 2005 Jul-Aug;16(4):873-84.

PMID:
16029029
18.

Selective modification of alternative splicing by indole derivatives that target serine-arginine-rich protein splicing factors.

Soret J, Bakkour N, Maire S, Durand S, Zekri L, Gabut M, Fic W, Divita G, Rivalle C, Dauzonne D, Nguyen CH, Jeanteur P, Tazi J.

Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8764-9. Epub 2005 Jun 6.

19.

Novel carbamate derivatives of 4-beta-amino-4'-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation.

Duca M, Arimondo PB, Léonce S, Pierré A, Pfeiffer B, Monneret C, Dauzonne D.

Org Biomol Chem. 2005 Mar 21;3(6):1074-80. Epub 2005 Feb 18.

PMID:
15750651
20.

Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives.

Duca M, Guianvarc'h D, Meresse P, Bertounesque E, Dauzonne D, Kraus-Berthier L, Thirot S, Léonce S, Pierré A, Pfeiffer B, Renard P, Arimondo PB, Monneret C.

J Med Chem. 2005 Jan 27;48(2):593-603.

PMID:
15658872
21.

Flavones and polyphenols inhibit the NO pathway during apoptosis of leukemia B-cells.

Quiney C, Dauzonne D, Kern C, Fourneron JD, Izard JC, Mohammad RM, Kolb JP, Billard C.

Leuk Res. 2004 Aug;28(8):851-61.

PMID:
15203283
22.

Synthesis and biological activity of sulfonamide derivatives of epipodophyllotoxin.

Guianvarc'h D, Duca M, Boukarim C, Kraus-Berthier L, Léonce S, Pierré A, Pfeiffer B, Renard P, Arimondo PB, Monneret C, Dauzonne D.

J Med Chem. 2004 Apr 22;47(9):2365-74.

PMID:
15084135
23.

The inducible NO synthase is downregulated during apoptosis of malignant cells from B-cell chronic lymphocytic leukemia induced by flavopiridol and polyphenols.

Billard C, Quiney C, Tang R, Kern C, Ajchenbaum-Cymbalista F, Dauzonne D, Kolb JP.

Ann N Y Acad Sci. 2003 Dec;1010:381-3.

PMID:
15033756
24.

Synthesis and biological evaluation of novel flavone-8-acetic acid derivatives as reversible inhibitors of aminopeptidase N/CD13.

Bauvois B, Puiffe ML, Bongui JB, Paillat S, Monneret C, Dauzonne D.

J Med Chem. 2003 Aug 28;46(18):3900-13.

PMID:
12930151
26.

The small GTPase Rab13 regulates assembly of functional tight junctions in epithelial cells.

Marzesco AM, Dunia I, Pandjaitan R, Recouvreur M, Dauzonne D, Benedetti EL, Louvard D, Zahraoui A.

Mol Biol Cell. 2002 Jun;13(6):1819-31.

27.

Actin filaments and myosin I alpha cooperate with microtubules for the movement of lysosomes.

Cordonnier MN, Dauzonne D, Louvard D, Coudrier E.

Mol Biol Cell. 2001 Dec;12(12):4013-29.

28.

Design of two etoposide-amsacrine conjugates: topoisomerase II and tubuline polymerization inhibition and relation to cytotoxicity.

Arimondo P, Boukarim C, Bailly C, Dauzonne D, Monneret C.

Anticancer Drug Des. 2000 Dec;15(6):413-21. Erratum in: Anticancer Drug Des 2001 Feb;16(1):71.

PMID:
11716434
29.

Synthesis and biological evaluation of 5-arylfuro[2,3-d]pyrimidines as novel dihydrofolate reductase inhibitors.

Wahid F, Monneret C, Dauzonne D.

Chem Pharm Bull (Tokyo). 1999 Feb;47(2):156-64.

PMID:
10071850
30.

Evaluation of the mutagenicity and antimutagenicity of forty-two 3-substituted flavones in the Ames test.

Beudot C, De Méo MP, Dauzonne D, Elias R, Laget M, Guiraud H, Balansard G, Duménil G.

Mutat Res. 1998 Sep 11;417(2-3):141-53.

PMID:
9733954
31.

Synthesis and biological evaluation of flavanones and flavones related to podophyllotoxin.

Gonzalez De Peredo A, Léonce S, Monneret C, Dauzonne D.

Chem Pharm Bull (Tokyo). 1998 Jan;46(1):79-83.

PMID:
9468639
32.

Main excretion metabolites of 7-methoxy-2-nitronaphtho[2,1-b]furan (R 7000) in rats.

Maurizis JC, Madelmont JC, Parry D, Dauzonne D, Royer R, Chabard JL.

Xenobiotica. 1986 Jul;16(7):635-43.

PMID:
3751118

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