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Items: 16


A protein nanocontainer targeting epithelial cancers: rational engineering, biochemical characterization, drug loading and cell delivery.

Ladurantie C, Coustets M, Czaplicki G, Demange P, Mazères S, Dauvillier S, Teissié J, Rols MP, Milon A, Ecochard V, Gross G, Paquereau L.

Nanoscale. 2019 Feb 14;11(7):3248-3260. doi: 10.1039/c8nr10249j.


Adipocytes promote breast cancer resistance to chemotherapy, a process amplified by obesity: role of the major vault protein (MVP).

Lehuédé C, Li X, Dauvillier S, Vaysse C, Franchet C, Clement E, Esteve D, Longué M, Chaltiel L, Le Gonidec S, Lazar I, Geneste A, Dumontet C, Valet P, Nieto L, Fallone F, Muller C.

Breast Cancer Res. 2019 Jan 17;21(1):7. doi: 10.1186/s13058-018-1088-6.


Periprostatic Adipose Tissue Favors Prostate Cancer Cell Invasion in an Obesity-Dependent Manner: Role of Oxidative Stress.

Laurent V, Toulet A, Attané C, Milhas D, Dauvillier S, Zaidi F, Clement E, Cinato M, Le Gonidec S, Guérard A, Lehuédé C, Garandeau D, Nieto L, Renaud-Gabardos E, Prats AC, Valet P, Malavaud B, Muller C.

Mol Cancer Res. 2019 Mar;17(3):821-835. doi: 10.1158/1541-7786.MCR-18-0748. Epub 2019 Jan 3.


Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells.

Wang YY, Attané C, Milhas D, Dirat B, Dauvillier S, Guerard A, Gilhodes J, Lazar I, Alet N, Laurent V, Le Gonidec S, Biard D, Hervé C, Bost F, Ren GS, Bono F, Escourrou G, Prentki M, Nieto L, Valet P, Muller C.

JCI Insight. 2017 Feb 23;2(4):e87489. doi: 10.1172/jci.insight.87489.


Adipocyte Exosomes Promote Melanoma Aggressiveness through Fatty Acid Oxidation: A Novel Mechanism Linking Obesity and Cancer.

Lazar I, Clement E, Dauvillier S, Milhas D, Ducoux-Petit M, LeGonidec S, Moro C, Soldan V, Dalle S, Balor S, Golzio M, Burlet-Schiltz O, Valet P, Muller C, Nieto L.

Cancer Res. 2016 Jul 15;76(14):4051-7. doi: 10.1158/0008-5472.CAN-16-0651. Epub 2016 May 23.


Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines.

Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S, Burlet-Schiltz O, Larue L, Muller C, Nieto L.

Pigment Cell Melanoma Res. 2015 Jul;28(4):464-75. doi: 10.1111/pcmr.12380. Epub 2015 May 30.


Adipocyte-derived fibroblasts promote tumor progression and contribute to the desmoplastic reaction in breast cancer.

Bochet L, Lehuédé C, Dauvillier S, Wang YY, Dirat B, Laurent V, Dray C, Guiet R, Maridonneau-Parini I, Le Gonidec S, Couderc B, Escourrou G, Valet P, Muller C.

Cancer Res. 2013 Sep 15;73(18):5657-68. doi: 10.1158/0008-5472.CAN-13-0530. Epub 2013 Jul 31.


Adipose tissue and breast epithelial cells: a dangerous dynamic duo in breast cancer.

Wang YY, Lehuédé C, Laurent V, Dirat B, Dauvillier S, Bochet L, Le Gonidec S, Escourrou G, Valet P, Muller C.

Cancer Lett. 2012 Nov 28;324(2):142-51. doi: 10.1016/j.canlet.2012.05.019. Epub 2012 May 27. Review.


GRK2 protein-mediated transphosphorylation contributes to loss of function of μ-opioid receptors induced by neuropeptide FF (NPFF2) receptors.

Moulédous L, Froment C, Dauvillier S, Burlet-Schiltz O, Zajac JM, Mollereau C.

J Biol Chem. 2012 Apr 13;287(16):12736-49. doi: 10.1074/jbc.M111.314617. Epub 2012 Feb 28.


A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia.

Bouquet F, Ousset M, Biard D, Fallone F, Dauvillier S, Frit P, Salles B, Muller C.

J Cell Sci. 2011 Jun 1;124(Pt 11):1943-51. doi: 10.1242/jcs.078030.


Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion.

Dirat B, Bochet L, Dabek M, Daviaud D, Dauvillier S, Majed B, Wang YY, Meulle A, Salles B, Le Gonidec S, Garrido I, Escourrou G, Valet P, Muller C.

Cancer Res. 2011 Apr 1;71(7):2455-65. doi: 10.1158/0008-5472.CAN-10-3323.


Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4.

Wu PY, Frit P, Meesala S, Dauvillier S, Modesti M, Andres SN, Huang Y, Sekiguchi J, Calsou P, Salles B, Junop MS.

Mol Cell Biol. 2009 Jun;29(11):3163-72. doi: 10.1128/MCB.01895-08. Epub 2009 Mar 30.


Transport of the leaderless protein Ku on the cell surface of activated monocytes regulates their migratory abilities.

Paupert J, Dauvillier S, Salles B, Muller C.

EMBO Rep. 2007 Jun;8(6):583-8. Epub 2007 May 11.


The membrane form of the DNA repair protein Ku interacts at the cell surface with metalloproteinase 9.

Monferran S, Paupert J, Dauvillier S, Salles B, Muller C.

EMBO J. 2004 Oct 1;23(19):3758-68. Epub 2004 Sep 23.


Intracellular single-chain variable fragments directed to the Src homology 2 domains of Syk partially inhibit Fc epsilon RI signaling in the RBL-2H3 cell line.

Dauvillier S, Mérida P, Visintin M, Cattaneo A, Bonnerot C, Dariavach P.

J Immunol. 2002 Sep 1;169(5):2274-83.


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