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Items: 35


Erratum to "Altered cytokine profile under control of the serotonergic system determines the regulation of CYP2C11 and CYP3A isoforms" [Food Chem. Toxicol. 116 Part B (2018) 369-378].

Kot M, Daujat-Chavanieu M.

Food Chem Toxicol. 2018 Aug;118:471-472. doi: 10.1016/j.fct.2018.05.028. Epub 2018 May 30. No abstract available.


Mitochondrial Complex I activity signals antioxidant response through ERK5.

Khan AUH, Allende-Vega N, Gitenay D, Garaude J, Vo DN, Belkhala S, Gerbal-Chaloin S, Gondeau C, Daujat-Chavanieu M, Delettre C, Orecchioni S, Talarico G, Bertolini F, Anel A, Cuezva JM, Enriquez JA, Cartron G, Lecellier CH, Hernandez J, Villalba M.

Sci Rep. 2018 May 9;8(1):7420. doi: 10.1038/s41598-018-23884-4.


Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes.

Abderrahmani A, Yengo L, Caiazzo R, Canouil M, Cauchi S, Raverdy V, Plaisance V, Pawlowski V, Lobbens S, Maillet J, Rolland L, Boutry R, Queniat G, Kwapich M, Tenenbaum M, Bricambert J, Saussenthaler S, Anthony E, Jha P, Derop J, Sand O, Rabearivelo I, Leloire A, Pigeyre M, Daujat-Chavanieu M, Gerbal-Chaloin S, Dayeh T, Lassailly G, Mathurin P, Staels B, Auwerx J, Schürmann A, Postic C, Schafmayer C, Hampe J, Bonnefond A, Pattou F, Froguel P.

Diabetes. 2018 Jul;67(7):1310-1321. doi: 10.2337/db17-1539. Epub 2018 May 4.


Altered cytokine profile under control of the serotonergic system determines the regulation of CYP2C11 and CYP3A isoforms.

Kot M, Daujat-Chavanieu M.

Food Chem Toxicol. 2018 Jun;116(Pt B):369-378. doi: 10.1016/j.fct.2018.04.051. Epub 2018 Apr 23. Erratum in: Food Chem Toxicol. 2018 Aug;118:471-472.


Improving Prediction of Metabolic Clearance Using Quantitative Extrapolation of Results Obtained From Human Hepatic Micropatterned Cocultures Model and by Considering the Impact of Albumin Binding.

Da-Silva F, Boulenc X, Vermet H, Compigne P, Gerbal-Chaloin S, Daujat-Chavanieu M, Klieber S, Poulin P.

J Pharm Sci. 2018 Jul;107(7):1957-1972. doi: 10.1016/j.xphs.2018.03.001. Epub 2018 Mar 7.


Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status.

Belkahla S, Haq Khan AU, Gitenay D, Alexia C, Gondeau C, Vo DN, Orecchioni S, Talarico G, Bertolini F, Cartron G, Hernandez J, Daujat-Chavanieu M, Allende-Vega N, Gonzalez MV.

Oncotarget. 2017 Dec 14;9(1):1114-1129. doi: 10.18632/oncotarget.23305. eCollection 2018 Jan 2.


Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor.

de Boussac H, Gondeau C, Briolotti P, Duret C, Treindl F, Römer M, Fabre JM, Herrero A, Ramos J, Maurel P, Templin M, Gerbal-Chaloin S, Daujat-Chavanieu M.

Drug Metab Dispos. 2018 Mar;46(3):223-236. doi: 10.1124/dmd.117.078683. Epub 2017 Dec 21.


Mesenchymal stem cells seeded on a human amniotic membrane improve liver regeneration and mouse survival after extended hepatectomy.

Despeyroux A, Duret C, Gondeau C, Perez-Gracia E, Chuttoo L, de Boussac H, Briolotti P, Bony C, Noël D, Jorgensen C, Larrey D, Daujat-Chavanieu M, Herrero A.

J Tissue Eng Regen Med. 2018 Apr;12(4):1062-1073. doi: 10.1002/term.2607. Epub 2017 Dec 5.


A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response.

Iroz A, Montagner A, Benhamed F, Levavasseur F, Polizzi A, Anthony E, Régnier M, Fouché E, Lukowicz C, Cauzac M, Tournier E, Do-Cruzeiro M, Daujat-Chavanieu M, Gerbal-Chalouin S, Fauveau V, Marmier S, Burnol AF, Guilmeau S, Lippi Y, Girard J, Wahli W, Dentin R, Guillou H, Postic C.

Cell Rep. 2017 Oct 10;21(2):403-416. doi: 10.1016/j.celrep.2017.09.065.


Evidence for an important role of host microRNAs in regulating hepatic fibrosis in humans infected with Schistosoma japonicum.

Cabantous S, Hou X, Louis L, He H, Mariani O, Sastre X, Daujat-Chavanieu M, Li Y, Dessein A.

Int J Parasitol. 2017 Nov;47(13):823-830. doi: 10.1016/j.ijpara.2017.05.007. Epub 2017 Jul 21.


Activation of the aryl hydrocarbon receptor decreases rifampicin-induced CYP3A4 expression in primary human hepatocytes and HepaRG.

Rasmussen MK, Daujat-Chavanieu M, Gerbal-Chaloin S.

Toxicol Lett. 2017 Aug 5;277:1-8. doi: 10.1016/j.toxlet.2017.05.029. Epub 2017 May 29.


MitoCeption: Transferring Isolated Human MSC Mitochondria to Glioblastoma Stem Cells.

Nzigou Mombo B, Gerbal-Chaloin S, Bokus A, Daujat-Chavanieu M, Jorgensen C, Hugnot JP, Vignais ML.

J Vis Exp. 2017 Feb 22;(120). doi: 10.3791/55245.


The impact of serotonergic system dysfunction on the regulation of P4501A isoforms during liver insufficiency and consequences for thyroid hormone homeostasis.

Kot M, Daujat-Chavanieu M.

Food Chem Toxicol. 2016 Nov;97:70-81. doi: 10.1016/j.fct.2016.08.027. Epub 2016 Aug 24.


Adult-Derived Human Liver Stem/Progenitor Cells Infused 3 Days Postsurgery Improve Liver Regeneration in a Mouse Model of Extended Hepatectomy.

Herrero A, Prigent J, Lombard C, Rosseels V, Daujat-Chavanieu M, Breckpot K, Najimi M, Deblandre G, Sokal EM.

Cell Transplant. 2017 Feb 16;26(2):351-364. doi: 10.3727/096368916X692960. Epub 2016 Sep 21.


Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes.

Rasmussen MK, Balaguer P, Ekstrand B, Daujat-Chavanieu M, Gerbal-Chaloin S.

PLoS One. 2016 May 3;11(5):e0154629. doi: 10.1371/journal.pone.0154629. eCollection 2016.


Correction: FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly.

Romano A, Hou X, Sertorio M, Dessein H, Cabantous S, Oliveira P, Li J, Oyegue S, Arnaud V, Luo X, Daujat-Chavanieu M, Mariani O, Sastre X, Dombey AM, He H, Li Y, Dessein A.

PLoS Negl Trop Dis. 2016 Feb 5;10(2):e0004454. doi: 10.1371/journal.pntd.0004454. eCollection 2016 Feb. No abstract available.


FOXP3+ Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly.

Romano A, Hou X, Sertorio M, Dessein H, Cabantous S, Oliveira P, Li J, Oyegue S, Arnaud V, Luo X, Daujat-Chavanieu M, Mariani O, Sastre X, Dombey AM, He H, Li Y, Dessein A.

PLoS Negl Trop Dis. 2016 Jan 5;10(1):e0004306. doi: 10.1371/journal.pntd.0004306. eCollection 2016 Jan. Erratum in: PLoS Negl Trop Dis. 2016 Feb;10(2):e0004454. Chavanieu, Martine [corrected to Daujat-Chavanieu, Martine].


Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds.

Delfosse V, Dendele B, Huet T, Grimaldi M, Boulahtouf A, Gerbal-Chaloin S, Beucher B, Roecklin D, Muller C, Rahmani R, Cavaillès V, Daujat-Chavanieu M, Vivat V, Pascussi JM, Balaguer P, Bourguet W.

Nat Commun. 2015 Sep 3;6:8089. doi: 10.1038/ncomms9089.


Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling.

Briolotti P, Chaloin L, Balaguer P, Da Silva F, Tománková V, Pascussi JM, Duret C, Fabre JM, Ramos J, Klieber S, Maurel P, Daujat-Chavanieu M, Gerbal-Chaloin S.

Toxicol Sci. 2015 Nov;148(1):261-75. doi: 10.1093/toxsci/kfv177. Epub 2015 Aug 10.


The non-proliferative nature of ascidian folliculogenesis as a model of highly ordered cellular topology distinct from proliferative epithelia.

Azzag K, Chelin Y, Rousset F, Le Goff E, Martinand-Mari C, Martinez AM, Maurin B, Daujat-Chavanieu M, Godefroy N, Averseng J, Mangeat P, Baghdiguian S.

PLoS One. 2015 May 22;10(5):e0126341. doi: 10.1371/journal.pone.0126341. eCollection 2015.


Novel role for carbohydrate responsive element binding protein in the control of ethanol metabolism and susceptibility to binge drinking.

Marmier S, Dentin R, Daujat-Chavanieu M, Guillou H, Bertrand-Michel J, Gerbal-Chaloin S, Girard J, Lotersztajn S, Postic C.

Hepatology. 2015 Oct;62(4):1086-100. doi: 10.1002/hep.27778. Epub 2015 May 6.


Cold Preservation of Human Adult Hepatocytes for Liver Cell Therapy.

Duret C, Moreno D, Balasiddaiah A, Roux S, Briolotti P, Raulet E, Herrero A, Ramet H, Biron-Andreani C, Gerbal-Chaloin S, Ramos J, Navarro F, Hardwigsen J, Maurel P, Aldabe R, Daujat-Chavanieu M.

Cell Transplant. 2015;24(12):2541-55. doi: 10.3727/096368915X687020. Epub 2015 Jan 23.


The WNT/β-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes.

Gerbal-Chaloin S, Dumé AS, Briolotti P, Klieber S, Raulet E, Duret C, Fabre JM, Ramos J, Maurel P, Daujat-Chavanieu M.

Mol Pharmacol. 2014 Dec;86(6):624-34. doi: 10.1124/mol.114.094797. Epub 2014 Sep 16.


In vitro infection of primary human hepatocytes by HCV-positive sera: insights on a highly relevant model.

Gondeau C, Briolotti P, Razafy F, Duret C, Rubbo PA, Helle F, Rème T, Ripault MP, Ducos J, Fabre JM, Ramos J, Pécheur EI, Larrey D, Maurel P, Daujat-Chavanieu M.

Gut. 2014 Sep;63(9):1490-500. doi: 10.1136/gutjnl-2013-304623. Epub 2013 Oct 23.


Usage of adenovirus expressing thymidine kinase mediated hepatocellular damage for enabling mouse liver repopulation with allogenic or xenogenic hepatocytes.

Moreno D, Balasiddaiah A, Lamas O, Duret C, Neri L, Guembe L, Galarraga M, Larrea E, Daujat-Chavanieu M, Muntane J, Maurel P, Riezu JI, Prieto J, Aldabe R.

PLoS One. 2013 Sep 24;8(9):e74948. doi: 10.1371/journal.pone.0074948. eCollection 2013.


Impact of alginate composition: from bead mechanical properties to encapsulated HepG2/C3A cell activities for in vivo implantation.

Capone SH, Dufresne M, Rechel M, Fleury MJ, Salsac AV, Paullier P, Daujat-Chavanieu M, Legallais C.

PLoS One. 2013 Apr 25;8(4):e62032. doi: 10.1371/journal.pone.0062032. Print 2013.


Nuclear receptors in the cross-talk of drug metabolism and inflammation.

Gerbal-Chaloin S, Iankova I, Maurel P, Daujat-Chavanieu M.

Drug Metab Rev. 2013 Feb;45(1):122-44. doi: 10.3109/03602532.2012.756011. Review.


Modular bioreactor for primary human hepatocyte culture: medium flow stimulates expression and activity of detoxification genes.

Vinci B, Duret C, Klieber S, Gerbal-Chaloin S, Sa-Cunha A, Laporte S, Suc B, Maurel P, Ahluwalia A, Daujat-Chavanieu M.

Biotechnol J. 2011 May;6(5):554-64. doi: 10.1002/biot.201000326. Epub 2011 Jan 21.


Comparison of hepatic-like cell production from human embryonic stem cells and adult liver progenitor cells: CAR transduction activates a battery of detoxification genes.

Funakoshi N, Duret C, Pascussi JM, Blanc P, Maurel P, Daujat-Chavanieu M, Gerbal-Chaloin S.

Stem Cell Rev Rep. 2011 Sep;7(3):518-31. doi: 10.1007/s12015-010-9225-3.


Isolation and culture of adult human liver progenitor cells: in vitro differentiation to hepatocyte-like cells.

Gerbal-Chaloin S, Duret C, Raulet E, Navarro F, Blanc P, Ramos J, Maurel P, Daujat-Chavanieu M.

Methods Mol Biol. 2010;640:247-60. doi: 10.1007/978-1-60761-688-7_12.


Microtubules-interfering agents restrict aryl hydrocarbon receptor-mediated CYP1A2 induction in primary cultures of human hepatocytes via c-jun-N-terminal kinase and glucocorticoid receptor.

Vrzal R, Daujat-Chavanieu M, Pascussi JM, Ulrichova J, Maurel P, Dvorak Z.

Eur J Pharmacol. 2008 Mar 10;581(3):244-54. doi: 10.1016/j.ejphar.2007.11.059. Epub 2007 Dec 3.


The tangle of nuclear receptors that controls xenobiotic metabolism and transport: crosstalk and consequences.

Pascussi JM, Gerbal-Chaloin S, Duret C, Daujat-Chavanieu M, Vilarem MJ, Maurel P.

Annu Rev Pharmacol Toxicol. 2008;48:1-32. Review.


Isolation, characterization, and differentiation to hepatocyte-like cells of nonparenchymal epithelial cells from adult human liver.

Duret C, Gerbal-Chaloin S, Ramos J, Fabre JM, Jacquet E, Navarro F, Blanc P, Sa-Cunha A, Maurel P, Daujat-Chavanieu M.

Stem Cells. 2007 Jul;25(7):1779-90. Epub 2007 Apr 5.


Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.

Duret C, Daujat-Chavanieu M, Pascussi JM, Pichard-Garcia L, Balaguer P, Fabre JM, Vilarem MJ, Maurel P, Gerbal-Chaloin S.

Mol Pharmacol. 2006 Jul;70(1):329-39. Epub 2006 Apr 11.


Role of CYP3A4 in the regulation of the aryl hydrocarbon receptor by omeprazole sulphide.

Gerbal-Chaloin S, Pichard-Garcia L, Fabre JM, Sa-Cunha A, Poellinger L, Maurel P, Daujat-Chavanieu M.

Cell Signal. 2006 May;18(5):740-50. Epub 2005 Aug 16.


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