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Links lipoproteins to chronic kidney disease and atherosclerosis.

Lu HS, Kukida M, Daugherty A.

Curr Opin Lipidol. 2019 Oct;30(5):410-411. doi: 10.1097/MOL.0000000000000625. No abstract available.


Measurements of the radiographic cardiac silhouette of ospreys (Pandion haliaetus).

Woo KMT, Barron GH, Daugherty AL, Woo JMP, Kehoe SP, Aguilar LAB, Cavanaugh SM.

Am J Vet Res. 2019 Sep;80(9):840-845. doi: 10.2460/ajvr.80.9.840.


Enhanced decision-making through multimodal training.

Zwilling CE, Daugherty AM, Hillman CH, Kramer AF, Cohen NJ, Barbey AK.

NPJ Sci Learn. 2019 Aug 5;4:11. doi: 10.1038/s41539-019-0049-x. eCollection 2019.


Ocular drugs and drug delivery systems - Current trends and future perspectives.

Rupenthal ID, Daugherty AL.

Drug Discov Today. 2019 Aug;24(8):1425-1426. doi: 10.1016/j.drudis.2019.07.005. Epub 2019 Jul 19. No abstract available.


Progress update from the hippocampal subfields group.

Olsen RK, Carr VA, Daugherty AM, La Joie R, Amaral RSC, Amunts K, Augustinack JC, Bakker A, Bender AR, Berron D, Boccardi M, Bocchetta M, Burggren AC, Chakravarty MM, Chételat G, de Flores R, DeKraker J, Ding SL, Geerlings MI, Huang Y, Insausti R, Johnson EG, Kanel P, Kedo O, Kennedy KM, Keresztes A, Lee JK, Lindenberger U, Mueller SG, Mulligan EM, Ofen N, Palombo DJ, Pasquini L, Pluta J, Raz N, Rodrigue KM, Schlichting ML, Lee Shing Y, Stark CEL, Steve TA, Suthana NA, Wang L, Werkle-Bergner M, Yushkevich PA, Yu Q, Wisse LEM; Hippocampal Subfields Group.

Alzheimers Dement (Amst). 2019 Jun 13;11:439-449. doi: 10.1016/j.dadm.2019.04.001. eCollection 2019 Dec.


Aortic Strain Correlates with Elastin Fragmentation in Fibrillin-1 Hypomorphic Mice.

Chen JZ, Sawada H, Moorleghen JJ, Weiland M, Daugherty A, Sheppard MB.

Circ Rep. 2019 May 10;1(5):199-205. doi: 10.1253/circrep.CR-18-0012. Epub 2019 Apr 27.


Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis.

Wu C, Lu W, Zhang Y, Zhang G, Shi X, Hisada Y, Grover SP, Zhang X, Li L, Xiang B, Shi J, Li XA, Daugherty A, Smyth SS, Kirchhofer D, Shiroishi T, Shao F, Mackman N, Wei Y, Li Z.

Immunity. 2019 Jun 18;50(6):1401-1411.e4. doi: 10.1016/j.immuni.2019.04.003. Epub 2019 May 7.


Differential Effects of Physiological Arousal Following Acute Stress on Police Officer Performance in a Simulated Critical Incident.

Arble E, Daugherty AM, Arnetz B.

Front Psychol. 2019 Apr 9;10:759. doi: 10.3389/fpsyg.2019.00759. eCollection 2019.


One amino acid change of Angiotensin II diminishes its effects on abdominal aortic aneurysm.

Wang Y, Xu Y, Wu C, Xia H, Wang Y, Nan J, Chen J, Yu H, Zhu W, Shi P, Daugherty A, Lu HS, Wang J.

Biosci Rep. 2019 May 3;39(5). pii: BSR20182055. doi: 10.1042/BSR20182055. Print 2019 May 31.


Updates on Approaches for Studying Atherosclerosis.

Wu C, Daugherty A, Lu HS.

Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):e108-e117. doi: 10.1161/ATVBAHA.119.312001. No abstract available.


Ultrasound Imaging of the Thoracic and Abdominal Aorta in Mice to Determine Aneurysm Dimensions.

Sawada H, Chen JZ, Wright BC, Moorleghen JJ, Lu HS, Daugherty A.

J Vis Exp. 2019 Mar 8;(145). doi: 10.3791/59013.


Mas receptor deficiency augments angiotensin II-induced atherosclerosis and aortic aneurysm ruptures in hypercholesterolemic male mice.

Stegbauer J, Thatcher SE, Yang G, Bottermann K, Rump LC, Daugherty A, Cassis LA.

J Vasc Surg. 2019 Mar 5. pii: S0741-5214(19)30127-2. doi: 10.1016/j.jvs.2018.11.045. [Epub ahead of print]


Targeting proprotein convertase subtilisin/kexin type 9 in mice and monkeys.

Wang Y, Ma M, Wang JA, Daugherty A, Lu HS.

Curr Opin Lipidol. 2019 Apr;30(2):154-155. doi: 10.1097/MOL.0000000000000583. No abstract available.


Updates of Recent Aortic Aneurysm Research.

Davis FM, Daugherty A, Lu HS.

Arterioscler Thromb Vasc Biol. 2019 Mar;39(3):e83-e90. doi: 10.1161/ATVBAHA.119.312000. No abstract available.


Recipients of the 2019 Early Career Investigator Awards.

Daugherty A.

Arterioscler Thromb Vasc Biol. 2019 May;39(5):835. doi: 10.1161/ATVBAHA.119.312479. No abstract available.


Angiotensinogen and Megalin Interactions Contribute to Atherosclerosis-Brief Report.

Ye F, Wang Y, Wu C, Howatt DA, Wu CH, Balakrishnan A, Mullick AE, Graham MJ, Danser AHJ, Wang J, Daugherty A, Lu HS.

Arterioscler Thromb Vasc Biol. 2019 Feb;39(2):150-155. doi: 10.1161/ATVBAHA.118.311817.


Antisense oligonucleotides targeting angiotensinogen: insights from animal studies.

Wu CH, Wang Y, Ma M, Mullick AE, Crooke RM, Graham MJ, Daugherty A, Lu HS.

Biosci Rep. 2019 Jan 11;39(1). pii: BSR20180201. doi: 10.1042/BSR20180201. Print 2019 Jan 31. Review.


Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells.

Hadi T, Boytard L, Silvestro M, Alebrahim D, Jacob S, Feinstein J, Barone K, Spiro W, Hutchison S, Simon R, Rateri D, Pinet F, Fenyo D, Adelman M, Moore KJ, Eltzschig HK, Daugherty A, Ramkhelawon B.

Nat Commun. 2018 Nov 27;9(1):5022. doi: 10.1038/s41467-018-07495-1.


Dysregulated NK cell PLCγ2 signaling and activity in juvenile dermatomyositis.

Throm AA, Alinger JB, Pingel JT, Daugherty AL, Pachman LM, French AR.

JCI Insight. 2018 Nov 15;3(22). pii: 123236. doi: 10.1172/jci.insight.123236.


Heterogeneity of Aortic Smooth Muscle Cells: A Determinant for Regional Characteristics of Thoracic Aortic Aneurysms?

Sawada H, Chen JZ, Wright BC, Sheppard MB, Lu HS, Daugherty A.

J Transl Int Med. 2018 Oct 9;6(3):93-96. doi: 10.2478/jtim-2018-0023. eCollection 2018 Sep. No abstract available.


Genetic predisposition for inflammation exacerbates effects of striatal iron content on cognitive switching ability in healthy aging.

Daugherty AM, Hoagey DA, Kennedy KM, Rodrigue KM.

Neuroimage. 2019 Jan 15;185:471-478. doi: 10.1016/j.neuroimage.2018.10.064. Epub 2018 Oct 25.


Agminated papules on the neck.

Daugherty A, Glass JS, Sorrells T.

Cutis. 2018 Sep;102(3):E5-E7. No abstract available.


LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Regulates Smooth Muscle Contractility by Modulating Ca2+ Signaling and Expression of Cytoskeleton-Related Proteins.

Au DT, Ying Z, Hernández-Ochoa EO, Fondrie WE, Hampton B, Migliorini M, Galisteo R, Schneider MF, Daugherty A, Rateri DL, Strickland DK, Muratoglu SC.

Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2651-2664. doi: 10.1161/ATVBAHA.118.311197.


SR-BI (Scavenger Receptor Class B Type 1) Is Critical in Maintaining Normal T-Cell Development and Enhancing Thymic Regeneration.

Zheng Z, Ai J, Guo L, Ye X, Bondada S, Howatt D, Daugherty A, Li XA.

Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2706-2717. doi: 10.1161/ATVBAHA.118.311728.


Reporting Sex and Sex Differences in Preclinical Studies.

Lu HS, Schmidt AM, Hegele RA, Mackman N, Rader DJ, Weber C, Daugherty A.

Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):e171-e184. doi: 10.1161/ATVBAHA.118.311717. No abstract available.


Proximal nail fold swelling, pain, and granulation tissue.

Daugherty A, Susong J.

JAAD Case Rep. 2018 Oct 5;4(9):905-906. doi: 10.1016/j.jdcr.2018.08.022. eCollection 2018 Oct. No abstract available.


Correction: Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis (doi: 10.1242/dmm.030130).

Olson PD, McLellan LK, Liu A, Briden KE, Tiemann KM, Daugherty AL, Hruska KA, Hunstad DA.

Dis Model Mech. 2018 Sep 13;11(9). pii: dmm036798. doi: 10.1242/dmm.036798. No abstract available.


Drebrin: a new player in angiotensin II-induced aortopathies.

Sawada H, Wright BC, Chen JZ, Lu HS, Daugherty A.

Cardiovasc Res. 2018 Nov 1;114(13):1699-1701. doi: 10.1093/cvr/cvy205. No abstract available.


Identification of enhanced IFN-γ signaling in polyarticular juvenile idiopathic arthritis with mass cytometry.

Throm AA, Moncrieffe H, Orandi AB, Pingel JT, Geurs TL, Miller HL, Daugherty AL, Malkova ON, Lovell DJ, Thompson SD, Grom AA, Cooper MA, Oh ST, French AR.

JCI Insight. 2018 Aug 9;3(15). pii: 121544. doi: 10.1172/jci.insight.121544. eCollection 2018 Aug 9.


Renin-Angiotensin System and Cardiovascular Functions.

Wu CH, Mohammadmoradi S, Chen JZ, Sawada H, Daugherty A, Lu HS.

Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):e108-e116. doi: 10.1161/ATVBAHA.118.311282. Review. No abstract available.


Developmental variation in regional brain iron and its relation to cognitive functions in childhood.

Hect JL, Daugherty AM, Hermez KM, Thomason ME.

Dev Cogn Neurosci. 2018 Nov;34:18-26. doi: 10.1016/j.dcn.2018.05.004. Epub 2018 May 22.


Models of first responder coping: Police officers as a unique population.

Arble E, Daugherty AM, Arnetz BB.

Stress Health. 2018 Dec;34(5):612-621. doi: 10.1002/smi.2821. Epub 2018 Jun 8.


Response by Daugherty et al to Letter Regarding Article, "Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies: A Statement From the Arteriosclerosis, Thrombosis, and Vascular Biology Council".

Daugherty A, Lu HS, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C.

Arterioscler Thromb Vasc Biol. 2018 Jun;38(6):e101-e102. doi: 10.1161/ATVBAHA.118.310988. No abstract available.


Ginkgo biloba extracts prevent aortic rupture in angiotensin II-infused hypercholesterolemic mice.

Huang XF, Zhang SZ, You YY, Zhang N, Lu H, Daugherty A, Xie XJ.

Acta Pharmacol Sin. 2019 Feb;40(2):192-198. doi: 10.1038/s41401-018-0017-7. Epub 2018 May 18.


Multifaceted functions of macrophages in atherosclerosis.

Wu CH, Daugherty A, Lu H.

Curr Opin Lipidol. 2018 Jun;29(3):275-276. doi: 10.1097/MOL.0000000000000513. No abstract available.


CD40L Deficiency Protects Against Aneurysm Formation.

Kusters PJH, Seijkens TTP, Beckers L, Lievens D, Winkels H, de Waard V, Duijvestijn A, Lindquist Liljeqvist M, Roy J, Daugherty A, Newby A, Gerdes N, Lutgens E.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):1076-1085. doi: 10.1161/ATVBAHA.117.310640. Epub 2018 Mar 8.


Deletion of BMAL1 in Smooth Muscle Cells Protects Mice From Abdominal Aortic Aneurysms.

Lutshumba J, Liu S, Zhong Y, Hou T, Daugherty A, Lu H, Guo Z, Gong MC.

Arterioscler Thromb Vasc Biol. 2018 May;38(5):1063-1075. doi: 10.1161/ATVBAHA.117.310153. Epub 2018 Feb 8.


Cilostazol Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysms but Not Atherosclerosis in Apolipoprotein E-Deficient Mice.

Umebayashi R, Uchida HA, Kakio Y, Subramanian V, Daugherty A, Wada J.

Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):903-912. doi: 10.1161/ATVBAHA.117.309707. Epub 2018 Feb 8.


In vitro model for predicting bioavailability of subcutaneously injected monoclonal antibodies.

Bown HK, Bonn C, Yohe S, Yadav DB, Patapoff TW, Daugherty A, Mrsny RJ.

J Control Release. 2018 Mar 10;273:13-20. doi: 10.1016/j.jconrel.2018.01.015. Epub 2018 Feb 6.


Adropin: An endocrine link between the biological clock and cholesterol homeostasis.

Ghoshal S, Stevens JR, Billon C, Girardet C, Sitaula S, Leon AS, Rao DC, Skinner JS, Rankinen T, Bouchard C, Nuñez MV, Stanhope KL, Howatt DA, Daugherty A, Zhang J, Schuelke M, Weiss EP, Coffey AR, Bennett BJ, Sethupathy P, Burris TP, Havel PJ, Butler AA.

Mol Metab. 2018 Feb;8:51-64. doi: 10.1016/j.molmet.2017.12.002. Epub 2017 Dec 30.


(Pro)renin Receptor Inhibition Reprograms Hepatic Lipid Metabolism and Protects Mice From Diet-Induced Obesity and Hepatosteatosis.

Ren L, Sun Y, Lu H, Ye D, Han L, Wang N, Daugherty A, Li F, Wang M, Su F, Tao W, Sun J, Zelcer N, Mullick AE, Danser AHJ, Jiang Y, He Y, Ruan X, Lu X.

Circ Res. 2018 Mar 2;122(5):730-741. doi: 10.1161/CIRCRESAHA.117.312422. Epub 2018 Jan 4.


Achondroplasia: Etiology, Clinical Presentation, and Management.

Daugherty A.

Neonatal Netw. 2017 Nov 1;36(6):337-342. doi: 10.1891/0730-0832.36.6.337. Review.


Optimization and validation of automated hippocampal subfield segmentation across the lifespan.

Bender AR, Keresztes A, Bodammer NC, Shing YL, Werkle-Bergner M, Daugherty AM, Yu Q, Kühn S, Lindenberger U, Raz N.

Hum Brain Mapp. 2018 Feb;39(2):916-931. doi: 10.1002/hbm.23891. Epub 2017 Nov 23.


Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans.

Daugherty AC, Yeo RW, Buenrostro JD, Greenleaf WJ, Kundaje A, Brunet A.

Genome Res. 2017 Dec;27(12):2096-2107. doi: 10.1101/gr.226233.117. Epub 2017 Nov 15.


Sex Chromosome Complement Defines Diffuse Versus Focal Angiotensin II-Induced Aortic Pathology.

Alsiraj Y, Thatcher SE, Blalock E, Fleenor B, Daugherty A, Cassis LA.

Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):143-153. doi: 10.1161/ATVBAHA.117.310035. Epub 2017 Nov 2.


Deletion of the NR4A nuclear receptor NOR1 in hematopoietic stem cells reduces inflammation but not abdominal aortic aneurysm formation.

Qing H, Jones KL, Heywood EB, Lu H, Daugherty A, Bruemmer D.

BMC Cardiovasc Disord. 2017 Oct 18;17(1):271. doi: 10.1186/s12872-017-0701-4.


Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine.

Kim HW, Blomkalns AL, Ogbi M, Thomas M, Gavrila D, Neltner BS, Cassis LA, Thompson RW, Weiss RM, Lindower PD, Blanco VM, McCormick ML, Daugherty A, Fu X, Hazen SL, Stansfield BK, Huo Y, Fulton DJ, Chatterjee T, Weintraub NL.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1168-H1179. doi: 10.1152/ajpheart.00296.2017. Epub 2017 Sep 29.


Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis.

Olson PD, McLellan LK, Liu A, Briden KE, Tiemann KM, Daugherty AL, Hruska KA, Hunstad DA.

Dis Model Mech. 2017 Nov 1;10(11):1371-1379. doi: 10.1242/dmm.030130. Epub 2017 Sep 7. Erratum in: Dis Model Mech. 2018 Sep 13;11(9):.


Widespread brain distribution and activity following i.c.v. infusion of anti-β-secretase (BACE1) in nonhuman primates.

Yadav DB, Maloney JA, Wildsmith KR, Fuji RN, Meilandt WJ, Solanoy H, Lu Y, Peng K, Wilson B, Chan P, Gadkar K, Kosky A, Goo M, Daugherty A, Couch JA, Keene T, Hayes K, Nikolas LJ, Lane D, Switzer R, Adams E, Watts RJ, Scearce-Levie K, Prabhu S, Shafer L, Thakker DR, Hildebrand K, Atwal JK.

Br J Pharmacol. 2017 Nov;174(22):4173-4185. doi: 10.1111/bph.14021. Epub 2017 Oct 6.


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