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Items: 1 to 50 of 83

1.
2.

Characterization of Aptamer BC 007 Substance and Product Using Circular Dichroism and Nuclear Magnetic Resonance Spectroscopy.

Weisshoff H, Wenzel K, Schulze-Rothe S, Nikolenko H, Davideit H, Becker NP, Göttel P, Srivatsa GS, Dathe M, Müller J, Haberland A.

J Pharm Sci. 2018 Aug;107(8):2033-2041. doi: 10.1016/j.xphs.2018.04.003. Epub 2018 Apr 18.

PMID:
29678593
3.

Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology.

Mechanic LE, Lindström S, Daily KM, Sieberts SK, Amos CI, Chen HS, Cox NJ, Dathe M, Feuer EJ, Guertin MJ, Hoffman J, Liu Y, Moore JH, Myers CL, Ritchie MD, Schildkraut J, Schumacher F, Witte JS, Wang W, Williams SM; U4C Challenge Participants; U4C Challenge Data Contributors, Gillanders EM.

PLoS Genet. 2017 Sep 28;13(9):e1006945. doi: 10.1371/journal.pgen.1006945. eCollection 2017 Sep. No abstract available.

4.

Antimicrobial peptide cWFW kills by combining lipid phase separation with autolysis.

Scheinpflug K, Wenzel M, Krylova O, Bandow JE, Dathe M, Strahl H.

Sci Rep. 2017 Mar 9;7:44332. doi: 10.1038/srep44332.

5.

Antifungal membranolytic activity of the tyrocidines against filamentous plant fungi.

Rautenbach M, Troskie AM, Vosloo JA, Dathe ME.

Biochimie. 2016 Nov;130:122-131. doi: 10.1016/j.biochi.2016.06.008. Epub 2016 Jun 18.

PMID:
27328781
6.

Lipopeptide-based micellar and liposomal carriers: Influence of surface charge and particle size on cellular uptake into blood brain barrier cells.

Sydow K, Nikolenko H, Lorenz D, Müller RH, Dathe M.

Eur J Pharm Biopharm. 2016 Dec;109:130-139. doi: 10.1016/j.ejpb.2016.09.019. Epub 2016 Oct 1.

PMID:
27702684
7.

The efficacy of trivalent cyclic hexapeptides to induce lipid clustering in PG/PE membranes correlates with their antimicrobial activity.

Finger S, Kerth A, Dathe M, Blume A.

Biochim Biophys Acta. 2015 Nov;1848(11 Pt A):2998-3006. doi: 10.1016/j.bbamem.2015.09.012. Epub 2015 Sep 12.

8.

Liquid storage of boar semen: Current and future perspectives on the use of cationic antimicrobial peptides to replace antibiotics in semen extenders.

Schulze M, Dathe M, Waberski D, Müller K.

Theriogenology. 2016 Jan 1;85(1):39-46. doi: 10.1016/j.theriogenology.2015.07.016. Epub 2015 Jul 18.

PMID:
26264695
9.

Challenges and Limits Using Antimicrobial Peptides in Boar Semen Preservation.

Schulze M, Grobbel M, Müller K, Junkes C, Dathe M, Rüdiger K, Jung M.

Reprod Domest Anim. 2015 Jul;50 Suppl 2:5-10. doi: 10.1111/rda.12553. Review.

PMID:
26174913
10.

Evidence for a novel mechanism of antimicrobial action of a cyclic R-,W-rich hexapeptide.

Scheinpflug K, Krylova O, Nikolenko H, Thurm C, Dathe M.

PLoS One. 2015 Apr 15;10(4):e0125056. doi: 10.1371/journal.pone.0125056. eCollection 2015.

11.

Anchoring dipalmitoyl phosphoethanolamine to nanoparticles boosts cellular uptake and fluorine-19 magnetic resonance signal.

Waiczies S, Lepore S, Sydow K, Drechsler S, Ku MC, Martin C, Lorenz D, Schütz I, Reimann HM, Purfürst B, Dieringer MA, Waiczies H, Dathe M, Pohlmann A, Niendorf T.

Sci Rep. 2015 Feb 12;5:8427. doi: 10.1038/srep08427.

12.

Cationic synthetic peptides: assessment of their antimicrobial potency in liquid preserved boar semen.

Speck S, Courtiol A, Junkes C, Dathe M, Müller K, Schulze M.

PLoS One. 2014 Aug 22;9(8):e105949. doi: 10.1371/journal.pone.0105949. eCollection 2014.

13.

Brain endothelial cell targeting via a peptide-functionalized liposomal carrier for xenon hyper-CEST MRI.

Schnurr M, Sydow K, Rose HM, Dathe M, Schröder L.

Adv Healthc Mater. 2015 Jan 7;4(1):40-5. doi: 10.1002/adhm.201400224. Epub 2014 Jul 1.

PMID:
24985966
14.

Effects of cationic antimicrobial peptides on liquid-preserved boar spermatozoa.

Schulze M, Junkes C, Mueller P, Speck S, Ruediger K, Dathe M, Mueller K.

PLoS One. 2014 Jun 18;9(6):e100490. doi: 10.1371/journal.pone.0100490. eCollection 2014.

15.

Kinetics and efficiency of a methyl-carboxylated 5-Fluorouracil-bovine serum albumin adduct for targeted delivery.

Koziol MJ, Sievers TK, Smuda K, Xiong Y, Müller A, Wojcik F, Steffen A, Dathe M, Georgieva R, Bäumler H.

Macromol Biosci. 2014 Mar;14(3):428-39. doi: 10.1002/mabi.201300363. Epub 2013 Nov 8.

PMID:
24821671
16.

Synergistic activity of the tyrocidines, antimicrobial cyclodecapeptides from Bacillus aneurinolyticus, with amphotericin B and caspofungin against Candida albicans biofilms.

Troskie AM, Rautenbach M, Delattin N, Vosloo JA, Dathe M, Cammue BP, Thevissen K.

Antimicrob Agents Chemother. 2014 Jul;58(7):3697-707. doi: 10.1128/AAC.02381-14. Epub 2014 Apr 21.

17.

What Goes around Comes around-A Comparative Study of the Influence of Chemical Modifications on the Antimicrobial Properties of Small Cyclic Peptides.

Scheinpflug K, Nikolenko H, Komarov IV, Rautenbach M, Dathe M.

Pharmaceuticals (Basel). 2013 Sep 6;6(9):1130-44. doi: 10.3390/ph6091130.

18.

Characterization of cell-penetrating lipopeptide micelles by spectroscopic methods.

Gehne S, Sydow K, Dathe M, Kumke MU.

J Phys Chem B. 2013 Nov 21;117(46):14215-25. doi: 10.1021/jp406053g. Epub 2013 Nov 12.

PMID:
24188016
19.

Effects of charge and charge distribution on the cellular uptake of multivalent arginine-containing peptide-polymer conjugates.

Koschek K, Dathe M, Rademann J.

Chembiochem. 2013 Oct 11;14(15):1982-90. doi: 10.1002/cbic.201300365. Epub 2013 Sep 24.

PMID:
24115335
20.

Topical enzyme-replacement therapy restores transglutaminase 1 activity and corrects architecture of transglutaminase-1-deficient skin grafts.

Aufenvenne K, Larcher F, Hausser I, Duarte B, Oji V, Nikolenko H, Del Rio M, Dathe M, Traupe H.

Am J Hum Genet. 2013 Oct 3;93(4):620-30. doi: 10.1016/j.ajhg.2013.08.003. Epub 2013 Sep 19.

21.

The helical propensity of KLA amphipathic peptides enhances their binding to gel-state lipid membranes.

Arouri A, Dathe M, Blume A.

Biophys Chem. 2013 Oct-Nov;180-181:10-21. doi: 10.1016/j.bpc.2013.05.003. Epub 2013 May 24.

PMID:
23792704
22.

Visualizing brain inflammation with a shingled-leg radio-frequency head probe for 19F/1H MRI.

Waiczies H, Lepore S, Drechsler S, Qadri F, Purfürst B, Sydow K, Dathe M, Kühne A, Lindel T, Hoffmann W, Pohlmann A, Niendorf T, Waiczies S.

Sci Rep. 2013;3:1280. doi: 10.1038/srep01280.

23.

Mode of action of cationic antimicrobial peptides defines the tethering position and the efficacy of biocidal surfaces.

Bagheri M, Beyermann M, Dathe M.

Bioconjug Chem. 2012 Jan 18;23(1):66-74. doi: 10.1021/bc200367f. Epub 2011 Dec 22.

PMID:
22148269
24.

The binding of an amphipathic peptide to lipid monolayers at the air/water interface is modulated by the lipid headgroup structure.

Arouri A, Kerth A, Dathe M, Blume A.

Langmuir. 2011 Mar 15;27(6):2811-8. doi: 10.1021/la104887s. Epub 2011 Feb 14.

PMID:
21319763
25.

Cyclic antimicrobial R-, W-rich peptides: the role of peptide structure and E. coli outer and inner membranes in activity and the mode of action.

Junkes C, Harvey RD, Bruce KD, Dölling R, Bagheri M, Dathe M.

Eur Biophys J. 2011 Apr;40(4):515-28. doi: 10.1007/s00249-011-0671-x. Epub 2011 Feb 1.

PMID:
21286704
26.

Morphological changes induced by the action of antimicrobial peptides on supported lipid bilayers.

Arouri A, Kiessling V, Tamm L, Dathe M, Blume A.

J Phys Chem B. 2011 Jan 13;115(1):158-67. doi: 10.1021/jp107577k. Epub 2010 Dec 15.

27.

Interaction of W-substituted analogs of cyclo-RRRWFW with bacterial lipopolysaccharides: the role of the aromatic cluster in antimicrobial activity.

Bagheri M, Keller S, Dathe M.

Antimicrob Agents Chemother. 2011 Feb;55(2):788-97. doi: 10.1128/AAC.01098-10. Epub 2010 Nov 22.

28.

Interaction of drug-carrier systems with targets--a study using atomic force microscopy.

Blaschke T, Spangenberg T, Schlupp P, Dathe M, Szcymczak W, Mehnert W, Korting HC, Thalhammer S, Niehus H, Schäfer-Korting M, Kramer KD.

Pharmazie. 2010 Sep;65(9):657-64.

PMID:
21038842
29.

Interactions of KLA amphipathic model peptides with lipid monolayers.

Erbe A, Kerth A, Dathe M, Blume A.

Chembiochem. 2009 Dec 14;10(18):2884-92. doi: 10.1002/cbic.200900444.

PMID:
19877001
30.

The role of apolipoprotein E in uptake of atovaquone into the brain in murine acute and reactivated toxoplasmosis.

Shubar HM, Dunay IR, Lachenmaier S, Dathe M, Bushrab FN, Mauludin R, Müller RH, Fitzner R, Borner K, Liesenfeld O.

J Drug Target. 2009 May;17(4):257-67. doi: 10.1080/10611860902718680.

PMID:
19255896
31.

Apolipoprotein E peptide-modified colloidal carriers: the design determines the mechanism of uptake in vascular endothelial cells.

Leupold E, Nikolenko H, Dathe M.

Biochim Biophys Acta. 2009 Feb;1788(2):442-9. doi: 10.1016/j.bbamem.2008.11.025. Epub 2008 Dec 14.

32.

Peptide induced demixing in PG/PE lipid mixtures: a mechanism for the specificity of antimicrobial peptides towards bacterial membranes?

Arouri A, Dathe M, Blume A.

Biochim Biophys Acta. 2009 Mar;1788(3):650-9. doi: 10.1016/j.bbamem.2008.11.022. Epub 2008 Dec 11.

33.

Well-defined, multifunctional nanostructures of a paramagnetic lipid and a lipopeptide for macrophage imaging.

Vucic E, Sanders HM, Arena F, Terreno E, Aime S, Nicolay K, Leupold E, Dathe M, Sommerdijk NA, Fayad ZA, Mulder WJ.

J Am Chem Soc. 2009 Jan 21;131(2):406-7. doi: 10.1021/ja808310u.

34.

Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence upon the activity spectrum.

Bagheri M, Beyermann M, Dathe M.

Antimicrob Agents Chemother. 2009 Mar;53(3):1132-41. doi: 10.1128/AAC.01254-08. Epub 2008 Dec 22.

35.

Incorporation of an apoE-derived lipopeptide in high-density lipoprotein MRI contrast agents for enhanced imaging of macrophages in atherosclerosis.

Chen W, Vucic E, Leupold E, Mulder WJ, Cormode DP, Briley-Saebo KC, Barazza A, Fisher EA, Dathe M, Fayad ZA.

Contrast Media Mol Imaging. 2008 Nov-Dec;3(6):233-42. doi: 10.1002/cmmi.257.

PMID:
19072768
36.

Insight into the role of HSPG in the cellular uptake of apolipoprotein E-derived peptide micelles and liposomes.

Leupold E, Nikolenko H, Beyermann M, Dathe M.

Biochim Biophys Acta. 2008 Dec;1778(12):2781-9. doi: 10.1016/j.bbamem.2008.09.008. Epub 2008 Sep 27.

37.

Nanoparticles for skin penetration enhancement--a comparison of a dendritic core-multishell-nanotransporter and solid lipid nanoparticles.

Küchler S, Radowski MR, Blaschke T, Dathe M, Plendl J, Haag R, Schäfer-Korting M, Kramer KD.

Eur J Pharm Biopharm. 2009 Feb;71(2):243-50. doi: 10.1016/j.ejpb.2008.08.019. Epub 2008 Aug 30.

PMID:
18796329
38.

Biophysics meets membrane-active peptides.

Castanho MA, Dathe M.

J Pept Sci. 2008 Apr;14(4):365-7. doi: 10.1002/psc.1013. No abstract available.

PMID:
18350572
39.

The interaction of arginine- and tryptophan-rich cyclic hexapeptides with Escherichia coli membranes.

Junkes C, Wessolowski A, Farnaud S, Evans RW, Good L, Bienert M, Dathe M.

J Pept Sci. 2008 Apr;14(4):535-43.

PMID:
17985396
40.

Structures of cyclic, antimicrobial peptides in a membrane-mimicking environment define requirements for activity.

Appelt C, Wessolowski A, Dathe M, Schmieder P.

J Pept Sci. 2008 Apr;14(4):524-7.

PMID:
17985394
41.

Synthesis of a chiral amino acid with bicyclo[1.1.1]pentane moiety and its incorporation into linear and cyclic antimicrobial peptides.

Pritz S, Pätzel M, Szeimies G, Dathe M, Bienert M.

Org Biomol Chem. 2007 Jun 7;5(11):1789-94. Epub 2007 May 4.

PMID:
17520148
42.

A simple fluorescence-spectroscopic membrane translocation assay.

Keller S, Böthe M, Bienert M, Dathe M, Blume A.

Chembiochem. 2007 Mar 26;8(5):546-52.

PMID:
17330902
43.

20S proteasome-dependent generation of an IEpp89 murine cytomegalovirus-derived H-2L(d) epitope from a recombinant protein.

Voigt A, Salzmann U, Seifert U, Dathe M, Soza A, Kloetzel PM, Kuckelkorn U.

Biochem Biophys Res Commun. 2007 Apr 6;355(2):549-54. Epub 2007 Feb 8.

PMID:
17303071
44.

Dipalmitoylation of a cellular uptake-mediating apolipoprotein E-derived peptide as a promising modification for stable anchorage in liposomal drug carriers.

Sauer I, Nikolenko H, Keller S, Abu Ajaj K, Bienert M, Dathe M.

Biochim Biophys Acta. 2006 Apr;1758(4):552-61. Epub 2006 Apr 7.

45.

High-affinity AKAP7delta-protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides.

Hundsrucker C, Krause G, Beyermann M, Prinz A, Zimmermann B, Diekmann O, Lorenz D, Stefan E, Nedvetsky P, Dathe M, Christian F, McSorley T, Krause E, McConnachie G, Herberg FW, Scott JD, Rosenthal W, Klussmann E.

Biochem J. 2006 Jun 1;396(2):297-306.

46.

Structure of the antimicrobial, cationic hexapeptide cyclo(RRWWRF) and its analogues in solution and bound to detergent micelles.

Appelt C, Wessolowski A, Söderhäll JA, Dathe M, Schmieder P.

Chembiochem. 2005 Sep;6(9):1654-62.

PMID:
16075425
47.

A critical reassessment of penetratin translocation across lipid membranes.

Bárány-Wallje E, Keller S, Serowy S, Geibel S, Pohl P, Bienert M, Dathe M.

Biophys J. 2005 Oct;89(4):2513-21. Epub 2005 Jul 22.

48.

Membrane-mimetic nanocarriers formed by a dipalmitoylated cell-penetrating peptide.

Keller S, Sauer I, Strauss H, Gast K, Dathe M, Bienert M.

Angew Chem Int Ed Engl. 2005 Aug 19;44(33):5252-5. No abstract available.

PMID:
16035010
49.

An apolipoprotein E-derived peptide mediates uptake of sterically stabilized liposomes into brain capillary endothelial cells.

Sauer I, Dunay IR, Weisgraber K, Bienert M, Dathe M.

Biochemistry. 2005 Feb 15;44(6):2021-9.

PMID:
15697227

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