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Items: 1 to 50 of 144

1.

Bisphenol exposure, hazard and regulation.

Willhite CC, Daston GP.

Toxicology. 2019 Sep 1;425:152243. doi: 10.1016/j.tox.2019.152243. Epub 2019 Jul 10. No abstract available.

PMID:
31301317
2.

Use of connectivity mapping to support read across: A deeper dive using data from 186 chemicals, 19 cell lines and 2 case studies.

De Abrew KN, Shan YK, Wang X, Krailler JM, Kainkaryam RM, Lester CC, Settivari RS, LeBaron MJ, Naciff JM, Daston GP.

Toxicology. 2019 Jul 1;423:84-94. doi: 10.1016/j.tox.2019.05.008. Epub 2019 May 21.

PMID:
31125584
3.

A mode-of-action ontology model for safety evaluation of chemicals: Outcome of a series of workshops on repeated dose toxicity.

Desprez B, Birk B, Blaauboer B, Boobis A, Carmichael P, Cronin MTD, Curie R, Daston G, Hubesch B, Jennings P, Klaric M, Kroese D, Mahony C, Ouédraogo G, Piersma A, Richarz AN, Schwarz M, van Benthem J, van de Water B, Vinken M.

Toxicol In Vitro. 2019 Sep;59:44-50. doi: 10.1016/j.tiv.2019.04.005. Epub 2019 Apr 4.

PMID:
30954655
4.

Best practices for developmental toxicity assessment for classification and labeling.

Daston G, Piersma A, Attias L, Beekhuijzen M, Chen C, Foreman J, Hallmark N, Leconte I.

Reprod Toxicol. 2018 Sep;80:44-48. doi: 10.1016/j.reprotox.2018.05.001. Epub 2018 May 16.

PMID:
29753929
5.

Is omphalocele a non-specific malformation in New Zealand White rabbits?

Daston GP, Beekhuijzen M.

Reprod Toxicol. 2018 Jun;78:29-39. doi: 10.1016/j.reprotox.2018.03.006. Epub 2018 Mar 14.

PMID:
29550350
6.

Rethinking developmental toxicity testing: Evolution or revolution?

Scialli AR, Daston G, Chen C, Coder PS, Euling SY, Foreman J, Hoberman AM, Hui J, Knudsen T, Makris SL, Morford L, Piersma AH, Stanislaus D, Thompson KE.

Birth Defects Res. 2018 Jun 1;110(10):840-850. doi: 10.1002/bdr2.1212. Epub 2018 Feb 12.

7.

Building a developmental toxicity ontology.

Baker N, Boobis A, Burgoon L, Carney E, Currie R, Fritsche E, Knudsen T, Laffont M, Piersma AH, Poole A, Schneider S, Daston G.

Birth Defects Res. 2018 Apr 3;110(6):502-518. doi: 10.1002/bdr2.1189. Epub 2018 Jan 31. Review.

PMID:
29383852
8.

Highlight report: 'Big data in the 3R's: outlook and recommendations', a roundtable summary.

Mahony C, Currie R, Daston G, Kleinstreuer N, van de Water B.

Arch Toxicol. 2018 Feb;92(2):1015-1020. doi: 10.1007/s00204-017-2145-0. Epub 2018 Jan 16. No abstract available.

PMID:
29340744
9.

Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop.

Buesen R, Chorley BN, da Silva Lima B, Daston G, Deferme L, Ebbels T, Gant TW, Goetz A, Greally J, Gribaldo L, Hackermüller J, Hubesch B, Jennen D, Johnson K, Kanno J, Kauffmann HM, Laffont M, McMullen P, Meehan R, Pemberton M, Perdichizzi S, Piersma AH, Sauer UG, Schmidt K, Seitz H, Sumida K, Tollefsen KE, Tong W, Tralau T, van Ravenzwaay B, Weber RJM, Worth A, Yauk C, Poole A.

Regul Toxicol Pharmacol. 2017 Dec;91 Suppl 1:S3-S13. doi: 10.1016/j.yrtph.2017.09.002. Epub 2017 Sep 25. Review.

10.

A unified birth defects research.

Daston GP, Tuan RS, Vekemans M.

Birth Defects Res. 2017 Jan 20;109(1):7. doi: 10.1002/bdra.23595. No abstract available.

PMID:
27905204
11.

FutureTox III: Bridges for Translation.

Juberg DR, Knudsen TB, Sander M, Beck NB, Faustman EM, Mendrick DL, Fowle JR 3rd, Hartung T, Tice RR, Lemazurier E, Becker RA, Fitzpatrick SC, Daston GP, Harrill A, Hines RN, Keller DA, Lipscomb JC, Watson D, Bahadori T, Crofton KM.

Toxicol Sci. 2017 Jan;155(1):22-31. doi: 10.1093/toxsci/kfw194. Epub 2016 Oct 25.

12.

Grouping 34 Chemicals Based on Mode of Action Using Connectivity Mapping.

De Abrew KN, Kainkaryam RM, Shan YK, Overmann GJ, Settivari RS, Wang X, Xu J, Adams RL, Tiesman JP, Carney EW, Naciff JM, Daston GP.

Toxicol Sci. 2016 Jun;151(2):447-61. doi: 10.1093/toxsci/kfw058. Epub 2016 Mar 29.

PMID:
27026708
13.

Dose- and Time-Dependent Transcriptional Response of Ishikawa Cells Exposed to Genistein.

Naciff JM, Khambatta ZS, Carr GJ, Tiesman JP, Singleton DW, Khan SA, Daston GP.

Toxicol Sci. 2016 May;151(1):71-87. doi: 10.1093/toxsci/kfw024. Epub 2016 Feb 10.

14.

Obituary. Edward W. Carney, 1959-2015.

Daston GP, Rogers JM.

Birth Defects Res B Dev Reprod Toxicol. 2015 Apr;104(2):53-4. doi: 10.1002/bdrb.21141. Epub 2015 Jun 11. No abstract available.

PMID:
26097067
15.

A strategy for safety assessment of chemicals with data gaps for developmental and/or reproductive toxicity.

Blackburn K, Daston G, Fisher J, Lester C, Naciff JM, Rufer ES, Stuard SB, Woeller K.

Regul Toxicol Pharmacol. 2015 Jul;72(2):202-15. doi: 10.1016/j.yrtph.2015.04.006. Epub 2015 Apr 21.

PMID:
25910676
16.

Assessment of health risks resulting from early-life exposures: Are current chemical toxicity testing protocols and risk assessment methods adequate?

Felter SP, Daston GP, Euling SY, Piersma AH, Tassinari MS.

Crit Rev Toxicol. 2015 Mar;45(3):219-44. doi: 10.3109/10408444.2014.993919. Epub 2015 Feb 17. Review.

PMID:
25687245
17.

A novel transcriptomics based in vitro method to compare and predict hepatotoxicity based on mode of action.

De Abrew KN, Overmann GJ, Adams RL, Tiesman JP, Dunavent J, Shan YK, Carr GJ, Daston GP, Naciff JM.

Toxicology. 2015 Feb 3;328:29-39. doi: 10.1016/j.tox.2014.11.008. Epub 2014 Dec 2.

PMID:
25475144
18.

Exposure-based validation list for developmental toxicity screening assays.

Daston GP, Beyer BK, Carney EW, Chapin RE, Friedman JM, Piersma AH, Rogers JM, Scialli AR.

Birth Defects Res B Dev Reprod Toxicol. 2014 Dec;101(6):423-8. doi: 10.1002/bdrb.21132. Epub 2014 Dec 4.

PMID:
25475026
19.

SEURAT: Safety Evaluation Ultimately Replacing Animal Testing--recommendations for future research in the field of predictive toxicology.

Daston G, Knight DJ, Schwarz M, Gocht T, Thomas RS, Mahony C, Whelan M.

Arch Toxicol. 2015 Jan;89(1):15-23. doi: 10.1007/s00204-014-1421-5. Epub 2014 Nov 30.

PMID:
25433540
20.

The SEURAT-1 approach towards animal free human safety assessment.

Gocht T, Berggren E, Ahr HJ, Cotgreave I, Cronin MT, Daston G, Hardy B, Heinzle E, Hescheler J, Knight DJ, Mahony C, Peschanski M, Schwarz M, Thomas RS, Verfaillie C, White A, Whelan M.

ALTEX. 2015;32(1):9-24. doi: 10.14573/altex.1408041. Epub 2014 Nov 5.

21.

Framework for identifying chemicals with structural features associated with the potential to act as developmental or reproductive toxicants.

Wu S, Fisher J, Naciff J, Laufersweiler M, Lester C, Daston G, Blackburn K.

Chem Res Toxicol. 2013 Dec 16;26(12):1840-61. doi: 10.1021/tx400226u. Epub 2013 Nov 22.

PMID:
24206190
22.

Perspectives on validation of high-throughput assays supporting 21st century toxicity testing.

Judson R, Kavlock R, Martin M, Reif D, Houck K, Knudsen T, Richard A, Tice RR, Whelan M, Xia M, Huang R, Austin C, Daston G, Hartung T, Fowle JR 3rd, Wooge W, Tong W, Dix D.

ALTEX. 2013;30(1):51-6. doi: 10.14573/altex.2013.1.051.

23.

Reprint of: Characterising hepatic mitochondrial function as a model for systemic toxicity: a commentary.

Leach AR, Wallace K, Alepee N, Daston G, Humphris C, Manou I, Modi S, Ringeissen S, Whelan M, Kimber I.

Toxicology. 2012 Dec 16;302(2-3):e1-4. doi: 10.1016/j.tox.2012.10.007. Epub 2012 Nov 8.

PMID:
23142426
24.

Characterising hepatic mitochondrial function as a model for systemic toxicity: a commentary.

Leach AR, Wallace K, Alepee N, Daston G, Humphris C, Manou I, Modi S, Ringeissen S, Whelan M, Kimber I.

Toxicology. 2012 Dec 8;302(1):96-9. No abstract available.

PMID:
23126011
25.

Effects of transplacental 17-α-ethynyl estradiol or bisphenol A on the developmental profile of steroidogenic acute regulatory protein in the rat testis.

Horstman KA, Naciff JM, Overmann GJ, Foertsch LM, Richardson BD, Daston GP.

Birth Defects Res B Dev Reprod Toxicol. 2012 Aug;95(4):318-25. doi: 10.1002/bdrb.21020. Epub 2012 Jul 2.

PMID:
22752971
26.

Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern.

Laufersweiler MC, Gadagbui B, Baskerville-Abraham IM, Maier A, Willis A, Scialli AR, Carr GJ, Felter SP, Blackburn K, Daston G.

Regul Toxicol Pharmacol. 2012 Feb;62(1):160-82. doi: 10.1016/j.yrtph.2011.09.004. Epub 2011 Oct 10.

PMID:
22019814
27.

Developmental toxicity testing for safety assessment: new approaches and technologies.

Knudsen TB, Kavlock RJ, Daston GP, Stedman D, Hixon M, Kim JH.

Birth Defects Res B Dev Reprod Toxicol. 2011 Oct;92(5):413-20. doi: 10.1002/bdrb.20315. Epub 2011 Jul 18. Review.

PMID:
21770025
28.

Laboratory models and their role in assessing teratogenesis.

Daston GP.

Am J Med Genet C Semin Med Genet. 2011 Aug 15;157C(3):183-7. doi: 10.1002/ajmg.c.30312. Epub 2011 Jul 15. Review.

PMID:
21766439
29.

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

Adler S, Basketter D, Creton S, Pelkonen O, van Benthem J, Zuang V, Andersen KE, Angers-Loustau A, Aptula A, Bal-Price A, Benfenati E, Bernauer U, Bessems J, Bois FY, Boobis A, Brandon E, Bremer S, Broschard T, Casati S, Coecke S, Corvi R, Cronin M, Daston G, Dekant W, Felter S, Grignard E, Gundert-Remy U, Heinonen T, Kimber I, Kleinjans J, Komulainen H, Kreiling R, Kreysa J, Leite SB, Loizou G, Maxwell G, Mazzatorta P, Munn S, Pfuhler S, Phrakonkham P, Piersma A, Poth A, Prieto P, Repetto G, Rogiers V, Schoeters G, Schwarz M, Serafimova R, Tähti H, Testai E, van Delft J, van Loveren H, Vinken M, Worth A, Zaldivar JM.

Arch Toxicol. 2011 May;85(5):367-485. doi: 10.1007/s00204-011-0693-2. Epub 2011 May 1. Review.

PMID:
21533817
30.

Case studies to test: A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments.

Blackburn K, Bjerke D, Daston G, Felter S, Mahony C, Naciff J, Robison S, Wu S.

Regul Toxicol Pharmacol. 2011 Jun;60(1):120-35. doi: 10.1016/j.yrtph.2011.03.002. Epub 2011 Mar 21.

PMID:
21420459
31.

A different approach to validating screening assays for developmental toxicity.

Daston GP, Chapin RE, Scialli AR, Piersma AH, Carney EW, Rogers JM, Friedman JM.

Birth Defects Res B Dev Reprod Toxicol. 2010 Dec;89(6):526-30. doi: 10.1002/bdrb.20276.

PMID:
21086491
32.

Predicting developmental toxicity through toxicogenomics.

Daston GP, Naciff JM.

Birth Defects Res C Embryo Today. 2010 Jun;90(2):110-7. doi: 10.1002/bdrc.20178. Review.

PMID:
20544695
33.

Computational toxicology: realizing the promise of the toxicity testing in the 21st century.

Rusyn I, Daston GP.

Environ Health Perspect. 2010 Aug;118(8):1047-50. doi: 10.1289/ehp.1001925. Epub 2010 May 18.

34.

The genomic response of Ishikawa cells to bisphenol A exposure is dose- and time-dependent.

Naciff JM, Khambatta ZS, Reichling TD, Carr GJ, Tiesman JP, Singleton DW, Khan SA, Daston GP.

Toxicology. 2010 Apr 11;270(2-3):137-49. doi: 10.1016/j.tox.2010.02.008. Epub 2010 Feb 17.

PMID:
20170705
35.

Introduction to special issue on developmental and reproductive toxicology in China.

Daston GP.

Birth Defects Res B Dev Reprod Toxicol. 2010 Feb;89(1):1. doi: 10.1002/bdrb.20239. No abstract available.

PMID:
20166228
36.

Inter-laboratory control data for reproductive endpoints required in the OPPTS 870.3800/OECD 416 reproduction and fertility test.

Marty MS, Allen B, Chapin RE, Cooper R, Daston GP, Flaws JA, Foster PM, Makris SL, Mylchreest E, Sandler D, Tyl RW.

Birth Defects Res B Dev Reprod Toxicol. 2009 Dec;86(6):470-89. doi: 10.1002/bdrb.20208.

PMID:
19918951
37.

Application of key events analysis to chemical carcinogens and noncarcinogens.

Boobis AR, Daston GP, Preston RJ, Olin SS.

Crit Rev Food Sci Nutr. 2009 Sep;49(8):690-707. doi: 10.1080/10408390903098673.

38.

Are in vitro tests suitable for regulatory use?

Hartung T, Daston G.

Toxicol Sci. 2009 Oct;111(2):233-7. doi: 10.1093/toxsci/kfp149. Epub 2009 Jul 17.

PMID:
19617452
39.

A modular approach to the extended one-generation reproduction toxicity study. The outcome of an ECETOC Task Force and International ECETOC/ECVAM Workshop.

Moore N, Bremer S, Carmichael N, Daston G, Dent M, Gaoua-Chapelle W, Hallmark N, Hartung T, Holzum B, Hübel U, Meisters ML, Schneider S, van Ravenzwaay B, Hennes C.

Altern Lab Anim. 2009 Apr;37(2):219-25. No abstract available.

PMID:
19453218
40.

The genomic response of a human uterine endometrial adenocarcinoma cell line to 17alpha-ethynyl estradiol.

Naciff JM, Khambatta ZS, Thomason RG, Carr GJ, Tiesman JP, Singleton DW, Khan SA, Daston GP.

Toxicol Sci. 2009 Jan;107(1):40-55. doi: 10.1093/toxsci/kfn219. Epub 2008 Oct 20.

PMID:
18936297
41.

State of the art in developmental toxicity screening methods and a way forward: a meeting report addressing embryonic stem cells, whole embryo culture, and zebrafish.

Chapin R, Augustine-Rauch K, Beyer B, Daston G, Finnell R, Flynn T, Hunter S, Mirkes P, O'Shea KS, Piersma A, Sandler D, Vanparys P, Van Maele-Fabry G.

Birth Defects Res B Dev Reprod Toxicol. 2008 Aug;83(4):446-56. doi: 10.1002/bdrb.20158.

42.

Identification and characterization of toxicity of contaminants in pet food leading to an outbreak of renal toxicity in cats and dogs.

Dobson RL, Motlagh S, Quijano M, Cambron RT, Baker TR, Pullen AM, Regg BT, Bigalow-Kern AS, Vennard T, Fix A, Reimschuessel R, Overmann G, Shan Y, Daston GP.

Toxicol Sci. 2008 Nov;106(1):251-62. doi: 10.1093/toxsci/kfn160. Epub 2008 Aug 9.

PMID:
18689873
43.

Gene expression, dose-response, and phenotypic anchoring: applications for toxicogenomics in risk assessment.

Daston GP.

Toxicol Sci. 2008 Oct;105(2):233-4. doi: 10.1093/toxsci/kfn138. Epub 2008 Aug 6. No abstract available.

PMID:
18684776
44.

CERHR bisphenol A: review and commentaries.

Daston GP.

Birth Defects Res B Dev Reprod Toxicol. 2008 Jun;83(3):151. doi: 10.1002/bdrb.20159. No abstract available.

PMID:
18570259
45.

Lack of effect of butylparaben and methylparaben on the reproductive system in male rats.

Hoberman AM, Schreur DK, Leazer T, Daston GP, Carthew P, Re T, Loretz L, Mann P.

Birth Defects Res B Dev Reprod Toxicol. 2008 Apr;83(2):123-33. doi: 10.1002/bdrb.20153.

PMID:
18393383
46.

Casimer T. Grabowski: 1927-2007.

Daston GP, Rogers JM.

Birth Defects Res B Dev Reprod Toxicol. 2008 Apr;83(2):149-50. doi: 10.1002/bdrb.20151. No abstract available.

PMID:
18383314
47.

Skeletal malformations and variations in developmental toxicity studies: interpretation issues for human risk assessment.

Daston GP, Seed J.

Birth Defects Res B Dev Reprod Toxicol. 2007 Dec;80(6):421-4. No abstract available.

PMID:
18157902
48.

Meeting report: hazard assessment for nanoparticles--report from an interdisciplinary workshop.

Balbus JM, Maynard AD, Colvin VL, Castranova V, Daston GP, Denison RA, Dreher KL, Goering PL, Goldberg AM, Kulinowski KM, Monteiro-Riviere NA, Oberdörster G, Omenn GS, Pinkerton KE, Ramos KS, Rest KM, Sass JB, Silbergeld EK, Wong BA.

Environ Health Perspect. 2007 Nov;115(11):1654-9.

49.

Uterine temporal response to acute exposure to 17alpha-ethinyl estradiol in the immature rat.

Naciff JM, Overmann GJ, Torontali SM, Carr GJ, Khambatta ZS, Tiesman JP, Richardson BD, Daston GP.

Toxicol Sci. 2007 Jun;97(2):467-90. Epub 2007 Mar 9.

PMID:
17351261
50.

Framework for use of toxicity screening tools in context-based decision-making.

Doull J, Borzelleca JF, Becker R, Daston G, DeSesso J, Fan A, Fenner-Crisp P, Holsapple M, Holson J, Craig Llewellyn G, MacGregor J, Seed J, Walls I, Woo YT, Olin S.

Food Chem Toxicol. 2007 May;45(5):759-96. Epub 2006 Nov 2.

PMID:
17215066

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