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Items: 40

1.

MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson's Disease Phenotype.

Geldenhuys WJ, Benkovic SA, Lin L, Yonutas HM, Crish SD, Sullivan PG, Darvesh AS, Brown CM, Richardson JR.

ACS Chem Neurosci. 2017 Dec 20;8(12):2759-2765. doi: 10.1021/acschemneuro.7b00287. Epub 2017 Sep 27.

2.

Structure-activity and in vivo evaluation of a novel lipoprotein lipase (LPL) activator.

Geldenhuys WJ, Caporoso J, Leeper TC, Lee YK, Lin L, Darvesh AS, Sadana P.

Bioorg Med Chem Lett. 2017 Jan 15;27(2):303-308. doi: 10.1016/j.bmcl.2016.11.053. Epub 2016 Nov 21.

3.

Emerging strategies of targeting lipoprotein lipase for metabolic and cardiovascular diseases.

Geldenhuys WJ, Lin L, Darvesh AS, Sadana P.

Drug Discov Today. 2017 Feb;22(2):352-365. doi: 10.1016/j.drudis.2016.10.007. Epub 2016 Oct 19. Review.

4.

Identification of small molecules that bind to the mitochondrial protein mitoNEET.

Geldenhuys WJ, Yonutas HM, Morris DL, Sullivan PG, Darvesh AS, Leeper TC.

Bioorg Med Chem Lett. 2016 Nov 1;26(21):5350-5353. doi: 10.1016/j.bmcl.2016.09.009. Epub 2016 Sep 6.

5.

Inducible Nitric Oxide Inhibitors Block NMDA Antagonist-Stimulated Motoric Behaviors and Medial Prefrontal Cortical Glutamate Efflux.

Bergstrom HC, Darvesh AS, Berger SP.

Front Pharmacol. 2015 Dec 15;6:292. doi: 10.3389/fphar.2015.00292. eCollection 2015.

6.

Evolution of a Natural Products and Nutraceuticals Course in the Pharmacy Curriculum.

Geldenhuys WJ, Cudnik ML, Krinsky DL, Darvesh AS.

Am J Pharm Educ. 2015 Aug 25;79(6):82. doi: 10.5688/ajpe79682.

7.

Pharmacotherapy of Alzheimer's disease: current and future trends.

Geldenhuys WJ, Darvesh AS.

Expert Rev Neurother. 2015 Jan;15(1):3-5. doi: 10.1586/14737175.2015.990884. Epub 2014 Dec 8. Review.

PMID:
25481975
8.

Pomegranate Bioactive Constituents Suppress Cell Proliferation and Induce Apoptosis in an Experimental Model of Hepatocellular Carcinoma: Role of Wnt/ β -Catenin Signaling Pathway.

Bhatia D, Thoppil RJ, Mandal A, Samtani KA, Darvesh AS, Bishayee A.

Evid Based Complement Alternat Med. 2013;2013:371813. doi: 10.1155/2013/371813. Epub 2013 Mar 28.

9.

Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer.

Darvesh AS, Bishayee A.

Nutr Cancer. 2013;65(3):329-44. doi: 10.1080/01635581.2013.767367. Review.

PMID:
23530632
10.

Chemopreventive effect of a novel oleanane triterpenoid in a chemically induced rodent model of breast cancer.

Bishayee A, Mandal A, Thoppil RJ, Darvesh AS, Bhatia D.

Int J Cancer. 2013 Sep 1;133(5):1054-63. doi: 10.1002/ijc.28108. Epub 2013 Mar 29.

11.

Dietary phytochemicals in the chemoprevention and treatment of hepatocellular carcinoma: in vivo evidence, molecular targets, and clinical relevance.

Bishayee A, Thoppil RJ, Waghray A, Kruse JA, Novotny NA, Darvesh AS.

Curr Cancer Drug Targets. 2012 Nov 1;12(9):1191-232. Review.

PMID:
22873222
12.

Angiogenesis in hepatocellular carcinoma: a potential target for chemoprevention and therapy.

Bishayee A, Darvesh AS.

Curr Cancer Drug Targets. 2012 Nov 1;12(9):1095-118. Review.

PMID:
22873221
13.

Black currant anthocyanins abrogate oxidative stress through Nrf2- mediated antioxidant mechanisms in a rat model of hepatocellular carcinoma.

Thoppil RJ, Bhatia D, Barnes KF, Haznagy-Radnai E, Hohmann J, Darvesh AS, Bishayee A.

Curr Cancer Drug Targets. 2012 Nov 1;12(9):1244-57.

PMID:
22873220
14.

Pomegranate phytoconstituents blunt the inflammatory cascade in a chemically induced rodent model of hepatocellular carcinogenesis.

Bishayee A, Thoppil RJ, Darvesh AS, Ohanyan V, Meszaros JG, Bhatia D.

J Nutr Biochem. 2013 Jan;24(1):178-87. doi: 10.1016/j.jnutbio.2012.04.009. Epub 2012 Jul 25.

PMID:
22841394
15.

Dimebon attenuates methamphetamine, but not MPTP, striatal dopamine depletion.

Geldenhuys WJ, Darvesh AS, Dluzen DE.

Neurochem Int. 2012 Jun;60(8):806-8. doi: 10.1016/j.neuint.2012.03.013. Epub 2012 Mar 28.

PMID:
22710395
16.

The health benefits of blackcurrants.

Gopalan A, Reuben SC, Ahmed S, Darvesh AS, Hohmann J, Bishayee A.

Food Funct. 2012 Aug;3(8):795-809. doi: 10.1039/c2fo30058c. Epub 2012 Jun 6. Review.

PMID:
22673662
17.

Curcumin and neurodegenerative diseases: a perspective.

Darvesh AS, Carroll RT, Bishayee A, Novotny NA, Geldenhuys WJ, Van der Schyf CJ.

Expert Opin Investig Drugs. 2012 Aug;21(8):1123-40. doi: 10.1517/13543784.2012.693479. Epub 2012 Jun 6. Review.

PMID:
22668065
18.

Markers associated with testosterone enhancement of methamphetamine-induced striatal dopaminergic neurotoxicity.

Buletko AB, Dluzen DE, McDermott JL, Darvesh AS, Geldenhuys WJ.

Neurotoxicol Teratol. 2012 May-Jun;34(3):338-43. doi: 10.1016/j.ntt.2012.03.003. Epub 2012 Apr 1.

PMID:
22521941
19.

Black currant phytoconstituents exert chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis by suppression of the inflammatory response.

Bishayee A, Thoppil RJ, Mandal A, Darvesh AS, Ohanyan V, Meszaros JG, Háznagy-Radnai E, Hohmann J, Bhatia D.

Mol Carcinog. 2013 Apr;52(4):304-17. doi: 10.1002/mc.21860. Epub 2011 Dec 27.

PMID:
22213170
20.

Markers associated with sex differences in methamphetamine-induced striatal dopamine neurotoxicity.

Dluzen DE, McDermott JL, Bourque M, Di Paolo T, Darvesh AS, Buletko AB, Laping NJ.

Curr Neuropharmacol. 2011 Mar;9(1):40-4. doi: 10.2174/157015911795017399.

21.

In vivo brain microdialysis: advances in neuropsychopharmacology and drug discovery.

Darvesh AS, Carroll RT, Geldenhuys WJ, Gudelsky GA, Klein J, Meshul CK, Van der Schyf CJ.

Expert Opin Drug Discov. 2011 Feb;6(2):109-127.

22.

Alteration of hepatic proinflammatory cytokines is involved in the resveratrol-mediated chemoprevention of chemically-induced hepatocarcinogenesis.

Mbimba T, Awale P, Bhatia D, Geldenhuys WJ, Darvesh AS, Carroll RT, Bishayee A.

Curr Pharm Biotechnol. 2012 Jan;13(1):229-34.

PMID:
21466437
23.

Natural products of dietary origin as lead compounds in virtual screening and drug design.

Geldenhuys WJ, Bishayee A, Darvesh AS, Carroll RT.

Curr Pharm Biotechnol. 2012 Jan;13(1):117-24. Review.

PMID:
21466431
24.

Curcumin and liver cancer: a review.

Darvesh AS, Aggarwal BB, Bishayee A.

Curr Pharm Biotechnol. 2012 Jan;13(1):218-28. Review.

PMID:
21466422
25.

Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms.

Bishayee A, Bhatia D, Thoppil RJ, Darvesh AS, Nevo E, Lansky EP.

Carcinogenesis. 2011 Jun;32(6):888-96. doi: 10.1093/carcin/bgr045. Epub 2011 Mar 9.

26.

Anthocyanin-rich black currant (Ribes nigrum L.) extract affords chemoprevention against diethylnitrosamine-induced hepatocellular carcinogenesis in rats.

Bishayee A, Mbimba T, Thoppil RJ, Háznagy-Radnai E, Sipos P, Darvesh AS, Folkesson HG, Hohmann J.

J Nutr Biochem. 2011 Nov;22(11):1035-46. doi: 10.1016/j.jnutbio.2010.09.001. Epub 2011 Jan 8.

PMID:
21216582
27.

Anthocyanin-rich black currant extract suppresses the growth of human hepatocellular carcinoma cells.

Bishayee A, Háznagy-Radnai E, Mbimba T, Sipos P, Morazzoni P, Darvesh AS, Bhatia D, Hohmann J.

Nat Prod Commun. 2010 Oct;5(10):1613-8.

PMID:
21121259
28.

Identification of novel monoamine oxidase B inhibitors by structure-based virtual screening.

Geldenhuys WJ, Darvesh AS, Funk MO, Van der Schyf CJ, Carroll RT.

Bioorg Med Chem Lett. 2010 Sep 1;20(17):5295-8. doi: 10.1016/j.bmcl.2010.06.128. Epub 2010 Jul 1.

PMID:
20650633
29.

Resveratrol and liver disease: from bench to bedside and community.

Bishayee A, Darvesh AS, Politis T, McGory R.

Liver Int. 2010 Sep;30(8):1103-14. doi: 10.1111/j.1478-3231.2010.02295.x. Epub 2010 Jun 14.

PMID:
20557453
30.

Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.

Bishayee A, Barnes KF, Bhatia D, Darvesh AS, Carroll RT.

Cancer Prev Res (Phila). 2010 Jun;3(6):753-63. doi: 10.1158/1940-6207.CAPR-09-0171. Epub 2010 May 25.

31.

Oxidative stress and Alzheimer's disease: dietary polyphenols as potential therapeutic agents.

Darvesh AS, Carroll RT, Bishayee A, Geldenhuys WJ, Van der Schyf CJ.

Expert Rev Neurother. 2010 May;10(5):729-45. doi: 10.1586/ern.10.42. Review.

PMID:
20420493
32.

Suppression of the inflammatory cascade is implicated in resveratrol chemoprevention of experimental hepatocarcinogenesis.

Bishayee A, Waghray A, Barnes KF, Mbimba T, Bhatia D, Chatterjee M, Darvesh AS.

Pharm Res. 2010 Jun;27(6):1080-91. doi: 10.1007/s11095-010-0144-4. Epub 2010 Apr 20.

PMID:
20405173
33.

Selenium in the prevention and treatment of hepatocellular carcinoma.

Darvesh AS, Bishayee A.

Anticancer Agents Med Chem. 2010 May;10(4):338-45. Review.

PMID:
20380634
34.

Relationships among gender, age, time, and temperature in methamphetamine-induced striatal dopaminergic neurotoxicity.

Dluzen DE, McDermott JL, Darvesh AS.

Neuroscience. 2010 Jun 2;167(4):985-93. doi: 10.1016/j.neuroscience.2010.02.076. Epub 2010 Mar 6.

PMID:
20211701
35.

Resveratrol in the chemoprevention and treatment of hepatocellular carcinoma.

Bishayee A, Politis T, Darvesh AS.

Cancer Treat Rev. 2010 Feb;36(1):43-53. doi: 10.1016/j.ctrv.2009.10.002. Epub 2009 Nov 11. Review.

PMID:
19910122
36.

Evidence for a role of energy dysregulation in the MDMA-induced depletion of brain 5-HT.

Darvesh AS, Gudelsky GA.

Brain Res. 2005 Sep 21;1056(2):168-75.

PMID:
16098955
37.

Evidence for the involvement of nitric oxide in 3,4-methylenedioxymethamphetamine-induced serotonin depletion in the rat brain.

Darvesh AS, Yamamoto BK, Gudelsky GA.

J Pharmacol Exp Ther. 2005 Feb;312(2):694-701. Epub 2004 Sep 29.

PMID:
15456837
38.
39.

Activation of 5-HT2 receptors induces glycogenolysis in the rat brain.

Darvesh AS, Gudelsky GA.

Eur J Pharmacol. 2003 Mar 19;464(2-3):135-40.

PMID:
12620505
40.

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