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Items: 1 to 50 of 200

1.

Nonenzymatically oxidized arachidonic acid regulates T-type Ca2+ currents in mouse spermatogenic cells.

Bondarenko O, Corzo G, Santana FL, Del Río-Portilla F, Darszon A, López-González I.

FEBS Lett. 2019 Jul;593(14):1735-1750. doi: 10.1002/1873-3468.13448. Epub 2019 Jun 6.

PMID:
31115913
2.

Analysis of sperm chemotaxis.

Ramírez-Gómez HV, Tuval I, Guerrero A, Darszon A.

Methods Cell Biol. 2019;151:473-486. doi: 10.1016/bs.mcb.2018.12.002. Epub 2019 Jan 28. Review.

PMID:
30948027
3.

Heterologous calcium-dependent inactivation of Orai1 by neighboring TRPV1 channels modulates cell migration and wound healing.

Bastián-Eugenio CE, Bohórquez-Hernández A, Pacheco J, Sampieri A, Asanov A, Ocelotl-Oviedo JP, Guerrero A, Darszon A, Vaca L.

Commun Biol. 2019 Mar 4;2:88. doi: 10.1038/s42003-019-0338-1. eCollection 2019.

4.

Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitor.

Zhao R, Kennedy K, De Blas GA, Orta G, Pavarotti MA, Arias RJ, de la Vega-Beltrán JL, Li Q, Dai H, Perozo E, Mayorga LS, Darszon A, Goldstein SAN.

Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11847-E11856. doi: 10.1073/pnas.1816189115. Epub 2018 Nov 26.

5.

Super-resolution imaging of live sperm reveals dynamic changes of the actin cytoskeleton during acrosomal exocytosis.

Romarowski A, Velasco Félix ÁG, Torres Rodríguez P, Gervasi MG, Xu X, Luque GM, Contreras-Jiménez G, Sánchez-Cárdenas C, Ramírez-Gómez HV, Krapf D, Visconti PE, Krapf D, Guerrero A, Darszon A, Buffone MG.

J Cell Sci. 2018 Nov 8;131(21). pii: jcs218958. doi: 10.1242/jcs.218958.

6.

CatSper channels are regulated by protein kinase A.

Orta G, de la Vega-Beltran JL, Martín-Hidalgo D, Santi CM, Visconti PE, Darszon A.

J Biol Chem. 2018 Oct 26;293(43):16830-16841. doi: 10.1074/jbc.RA117.001566. Epub 2018 Sep 13.

PMID:
30213858
7.

Tyrosine phosphorylation signaling regulates Ca2+ entry by affecting intracellular pH during human sperm capacitation.

Brukman NG, Nuñez SY, Puga Molina LDC, Buffone MG, Darszon A, Cuasnicu PS, Da Ros VG.

J Cell Physiol. 2019 Apr;234(4):5276-5288. doi: 10.1002/jcp.27337. Epub 2018 Sep 10.

PMID:
30203545
8.

3-D Human Sperm Flagellum Tracing in Low SNR Fluorescence Images.

Hernandez-Herrera P, Montoya F, Rendon-Mancha JM, Darszon A, Corkidi G.

IEEE Trans Med Imaging. 2018 Oct;37(10):2236-2247. doi: 10.1109/TMI.2018.2840047. Epub 2018 May 23.

PMID:
29993713
9.

Intracellular Ca2+ threshold reversibly switches flagellar beat off and on.

Sánchez-Cárdenas C, Montoya F, Navarrete FA, Hernández-Cruz A, Corkidi G, Visconti PE, Darszon A.

Biol Reprod. 2018 Nov 1;99(5):1010-1021. doi: 10.1093/biolre/ioy132.

PMID:
29893793
10.

CFTR/ENaC-dependent regulation of membrane potential during human sperm capacitation is initiated by bicarbonate uptake through NBC.

Puga Molina LC, Pinto NA, Torres NI, González-Cota AL, Luque GM, Balestrini PA, Romarowski A, Krapf D, Santi CM, Treviño CL, Darszon A, Buffone MG.

J Biol Chem. 2018 Jun 22;293(25):9924-9936. doi: 10.1074/jbc.RA118.003166. Epub 2018 May 9.

11.

Disruption of protein kinase A localization induces acrosomal exocytosis in capacitated mouse sperm.

Stival C, Ritagliati C, Xu X, Gervasi MG, Luque GM, Baró Graf C, De la Vega-Beltrán JL, Torres N, Darszon A, Krapf D, Buffone MG, Visconti PE, Krapf D.

J Biol Chem. 2018 Jun 15;293(24):9435-9447. doi: 10.1074/jbc.RA118.002286. Epub 2018 Apr 26.

12.

pH-dependent Ca+2 oscillations prevent untimely acrosome reaction in human sperm.

Mata-Martínez E, Darszon A, Treviño CL.

Biochem Biophys Res Commun. 2018 Feb 26;497(1):146-152. doi: 10.1016/j.bbrc.2018.02.042. Epub 2018 Feb 8.

PMID:
29427664
13.

Acrosomal alkalization triggers Ca2+ release and acrosome reaction in mammalian spermatozoa.

Chávez JC, De la Vega-Beltrán JL, José O, Torres P, Nishigaki T, Treviño CL, Darszon A.

J Cell Physiol. 2018 Jun;233(6):4735-4747. doi: 10.1002/jcp.26262. Epub 2018 Jan 4.

PMID:
29135027
14.

Are there intracellular Ca2+ oscillations correlated with flagellar beating in human sperm? A three vs. two-dimensional analysis.

Corkidi G, Montoya F, Hernández-Herrera P, Ríos-Herrera WA, Müller MF, Treviño CL, Darszon A.

Mol Hum Reprod. 2017 Sep 1;23(9):583-593. doi: 10.1093/molehr/gax039.

PMID:
28911211
15.

Network model predicts that CatSper is the main Ca2+ channel in the regulation of sea urchin sperm motility.

Espinal-Enríquez J, Priego-Espinosa DA, Darszon A, Beltrán C, Martínez-Mekler G.

Sci Rep. 2017 Jun 26;7(1):4236. doi: 10.1038/s41598-017-03857-9.

16.

Essential Role of CFTR in PKA-Dependent Phosphorylation, Alkalinization, and Hyperpolarization During Human Sperm Capacitation.

Puga Molina LC, Pinto NA, Torres Rodríguez P, Romarowski A, Vicens Sanchez A, Visconti PE, Darszon A, Treviño CL, Buffone MG.

J Cell Physiol. 2017 Jun;232(6):1404-1414. doi: 10.1002/jcp.25634. Epub 2016 Oct 26.

17.

Transient exposure to calcium ionophore enables in vitro fertilization in sterile mouse models.

Navarrete FA, Alvau A, Lee HC, Levin LR, Buck J, Leon PM, Santi CM, Krapf D, Mager J, Fissore RA, Salicioni AM, Darszon A, Visconti PE.

Sci Rep. 2016 Sep 15;6:33589. doi: 10.1038/srep33589.

18.

The tyrosine kinase FER is responsible for the capacitation-associated increase in tyrosine phosphorylation in murine sperm.

Alvau A, Battistone MA, Gervasi MG, Navarrete FA, Xu X, Sánchez-Cárdenas C, De la Vega-Beltran JL, Da Ros VG, Greer PA, Darszon A, Krapf D, Salicioni AM, Cuasnicu PS, Visconti PE.

Development. 2016 Jul 1;143(13):2325-33. doi: 10.1242/dev.136499. Epub 2016 May 25.

19.

Role of Ion Channels in the Sperm Acrosome Reaction.

Beltrán C, Treviño CL, Mata-Martínez E, Chávez JC, Sánchez-Cárdenas C, Baker M, Darszon A.

Adv Anat Embryol Cell Biol. 2016;220:35-69. doi: 10.1007/978-3-319-30567-7_3. Review.

PMID:
27194349
20.

A Specific Transitory Increase in Intracellular Calcium Induced by Progesterone Promotes Acrosomal Exocytosis in Mouse Sperm.

Romarowski A, Sánchez-Cárdenas C, Ramírez-Gómez HV, Puga Molina Ldel C, Treviño CL, Hernández-Cruz A, Darszon A, Buffone MG.

Biol Reprod. 2016 Mar;94(3):63. doi: 10.1095/biolreprod.115.136085. Epub 2016 Jan 27.

21.

Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.

García-Rincón J, Darszon A, Beltrán C.

Biochim Biophys Acta. 2016 Apr;1857(4):415-26. doi: 10.1016/j.bbabio.2016.01.003. Epub 2016 Jan 6.

22.

CRISP1 as a novel CatSper regulator that modulates sperm motility and orientation during fertilization.

Ernesto JI, Weigel Muñoz M, Battistone MA, Vasen G, Martínez-López P, Orta G, Figueiras-Fierro D, De la Vega-Beltran JL, Moreno IA, Guidobaldi HA, Giojalas L, Darszon A, Cohen DJ, Cuasnicú PS.

J Cell Biol. 2015 Sep 28;210(7):1213-24. doi: 10.1083/jcb.201412041.

23.

Pharmacology of hSlo3 channels and their contribution in the capacitation-associated hyperpolarization of human sperm.

Sánchez-Carranza O, Torres-Rodríguez P, Darszon A, Treviño CL, López-González I.

Biochem Biophys Res Commun. 2015 Oct 23;466(3):554-9. doi: 10.1016/j.bbrc.2015.09.073. Epub 2015 Sep 14.

PMID:
26381170
24.

Regulation of Spermatogenic Cell T-Type Ca(2+) Currents by Zn(2+): Implications in Male Reproductive Physiology.

López-González I, Treviño CL, Darszon A.

J Cell Physiol. 2016 Mar;231(3):659-67. doi: 10.1002/jcp.25112.

PMID:
26222306
25.

Single cell imaging reveals that the motility regulator speract induces a flagellar alkalinization that precedes and is independent of Ca²⁺ influx in sea urchin spermatozoa.

González-Cota AL, Silva PÂ, Carneiro J, Darszon A.

FEBS Lett. 2015 Jul 22;589(16):2146-54. doi: 10.1016/j.febslet.2015.06.024. Epub 2015 Jul 2.

26.

Flow cytometry analysis reveals that only a subpopulation of mouse sperm undergoes hyperpolarization during capacitation.

Escoffier J, Navarrete F, Haddad D, Santi CM, Darszon A, Visconti PE.

Biol Reprod. 2015 May;92(5):121. doi: 10.1095/biolreprod.114.127266. Epub 2015 Apr 8.

27.

Biphasic role of calcium in mouse sperm capacitation signaling pathways.

Navarrete FA, García-Vázquez FA, Alvau A, Escoffier J, Krapf D, Sánchez-Cárdenas C, Salicioni AM, Darszon A, Visconti PE.

J Cell Physiol. 2015 Aug;230(8):1758-1769. doi: 10.1002/jcp.24873.

28.

Imaging of the 3D dynamics of flagellar beating in human sperm.

Silva-Villalobos F, Pimentel JA, Darszon A, Corkidi G.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:190-3. doi: 10.1109/EMBC.2014.6943561.

PMID:
25569929
29.

SLO3 K+ channels control calcium entry through CATSPER channels in sperm.

Chávez JC, Ferreira JJ, Butler A, De La Vega Beltrán JL, Treviño CL, Darszon A, Salkoff L, Santi CM.

J Biol Chem. 2014 Nov 14;289(46):32266-75. doi: 10.1074/jbc.M114.607556. Epub 2014 Sep 30.

30.

In silico determination of the effect of multi-target drugs on calcium dynamics signaling network underlying sea urchin spermatozoa motility.

Espinal-Enríquez J, Darszon A, Guerrero A, Martínez-Mekler G.

PLoS One. 2014 Aug 27;9(8):e104451. doi: 10.1371/journal.pone.0104451. eCollection 2014.

31.

Acrosome reaction and Ca²⁺ imaging in single human spermatozoa: new regulatory roles of [Ca²⁺]i.

Sánchez-Cárdenas C, Servín-Vences MR, José O, Treviño CL, Hernández-Cruz A, Darszon A.

Biol Reprod. 2014 Sep;91(3):67. doi: 10.1095/biolreprod.114.119768. Epub 2014 Aug 6.

32.

Zn(2+) induces hyperpolarization by activation of a K(+) channel and increases intracellular Ca(2+) and pH in sea urchin spermatozoa.

Beltrán C, Rodríguez-Miranda E, Granados-González G, de De la Torre LG, Nishigaki T, Darszon A.

Dev Biol. 2014 Oct 1;394(1):15-23. doi: 10.1016/j.ydbio.2014.07.017. Epub 2014 Aug 1. Review.

33.

Soluble adenylyl cyclase of sea urchin spermatozoa.

Vacquier VD, Loza-Huerta A, García-Rincón J, Darszon A, Beltrán C.

Biochim Biophys Acta. 2014 Dec;1842(12 Pt B):2621-8. doi: 10.1016/j.bbadis.2014.07.011. Epub 2014 Jul 23. Review.

34.

Intracellular pH in sperm physiology.

Nishigaki T, José O, González-Cota AL, Romero F, Treviño CL, Darszon A.

Biochem Biophys Res Commun. 2014 Aug 1;450(3):1149-58. doi: 10.1016/j.bbrc.2014.05.100. Epub 2014 Jun 2. Review.

35.

Membrane hyperpolarization during human sperm capacitation.

López-González I, Torres-Rodríguez P, Sánchez-Carranza O, Solís-López A, Santi CM, Darszon A, Treviño CL.

Mol Hum Reprod. 2014 Jul;20(7):619-29. doi: 10.1093/molehr/gau029. Epub 2014 Apr 15.

36.

T-type Ca2+ channels in spermatogenic cells and sperm.

Darszon A, Hernández-Cruz A.

Pflugers Arch. 2014 Apr;466(4):819-31. doi: 10.1007/s00424-014-1478-2. Epub 2014 Mar 6. Review.

PMID:
24595474
37.

Compartmentalization of distinct cAMP signaling pathways in mammalian sperm.

Wertheimer E, Krapf D, de la Vega-Beltran JL, Sánchez-Cárdenas C, Navarrete F, Haddad D, Escoffier J, Salicioni AM, Levin LR, Buck J, Mager J, Darszon A, Visconti PE.

J Biol Chem. 2013 Dec 6;288(49):35307-20. doi: 10.1074/jbc.M113.489476. Epub 2013 Oct 15.

38.

Ca2+ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways.

Tateno H, Krapf D, Hino T, Sánchez-Cárdenas C, Darszon A, Yanagimachi R, Visconti PE.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18543-8. doi: 10.1073/pnas.1317113110. Epub 2013 Oct 15.

39.

Certain Strongylocentrotus purpuratus sperm mitochondrial proteins co-purify with low density detergent-insoluble membranes and are PKA or PKC-substrates possibly involved in sperm motility regulation.

Loza-Huerta A, Vera-Estrella R, Darszon A, Beltrán C.

Biochim Biophys Acta. 2013 Nov;1830(11):5305-15. doi: 10.1016/j.bbagen.2013.07.029. Epub 2013 Aug 6.

PMID:
23928041
40.

The anti-inflammatory drug celecoxib inhibits T-type Ca2+ currents in spermatogenic cells yet it elicits the acrosome reaction in mature sperm.

Balderas E, Sánchez-Cárdenas C, Chávez JC, de la Vega Beltrán JL, Gómez-Lagunas F, Treviño CL, Darszon A.

FEBS Lett. 2013 Aug 2;587(15):2412-9. doi: 10.1016/j.febslet.2013.05.068. Epub 2013 Jun 13.

41.

Ion permeabilities in mouse sperm reveal an external trigger for SLO3-dependent hyperpolarization.

Chávez JC, de la Vega-Beltrán JL, Escoffier J, Visconti PE, Treviño CL, Darszon A, Salkoff L, Santi CM.

PLoS One. 2013;8(4):e60578. doi: 10.1371/journal.pone.0060578. Epub 2013 Apr 5.

42.

Niflumic acid disrupts marine spermatozoan chemotaxis without impairing the spatiotemporal detection of chemoattractant gradients.

Guerrero A, Espinal J, Wood CD, Rendón JM, Carneiro J, Martínez-Mekler G, Darszon A.

J Cell Sci. 2013 Mar 15;126(Pt 6):1477-87. doi: 10.1242/jcs.121442. Epub 2013 Feb 15.

43.

K+ and Cl- channels and transporters in sperm function.

Santi CM, Orta G, Salkoff L, Visconti PE, Darszon A, Treviño CL.

Curr Top Dev Biol. 2013;102:385-421. doi: 10.1016/B978-0-12-416024-8.00014-3. Review.

44.

Mouse sperm membrane potential hyperpolarization is necessary and sufficient to prepare sperm for the acrosome reaction.

De La Vega-Beltran JL, Sánchez-Cárdenas C, Krapf D, Hernandez-González EO, Wertheimer E, Treviño CL, Visconti PE, Darszon A.

J Biol Chem. 2012 Dec 28;287(53):44384-93. doi: 10.1074/jbc.M112.393488. Epub 2012 Oct 24.

45.

Acute slices of mice testis seminiferous tubules unveil spontaneous and synchronous Ca2+ oscillations in germ cell clusters.

Sánchez-Cárdenas C, Guerrero A, Treviño CL, Hernández-Cruz A, Darszon A.

Biol Reprod. 2012 Oct 18;87(4):92. doi: 10.1095/biolreprod.112.100255. Print 2012 Oct.

46.

Electrophysiological evidence for the presence of cystic fibrosis transmembrane conductance regulator (CFTR) in mouse sperm.

Figueiras-Fierro D, Acevedo JJ, Martínez-López P, Escoffier J, Sepúlveda FV, Balderas E, Orta G, Visconti PE, Darszon A.

J Cell Physiol. 2013 Mar;228(3):590-601. doi: 10.1002/jcp.24166.

47.

Are TRP channels involved in sperm development and function?

Darszon A, Sánchez-Cárdenas C, Orta G, Sánchez-Tusie AA, Beltrán C, López-González I, Granados-González G, Treviño CL.

Cell Tissue Res. 2012 Sep;349(3):749-64. doi: 10.1007/s00441-012-1397-5. Epub 2012 May 15. Review.

PMID:
22580508
48.

A caged progesterone analog alters intracellular Ca2+ and flagellar bending in human sperm.

Servin-Vences MR, Tatsu Y, Ando H, Guerrero A, Yumoto N, Darszon A, Nishigaki T.

Reproduction. 2012 Jul;144(1):101-9. doi: 10.1530/REP-11-0268. Epub 2012 May 11.

PMID:
22580372
49.

Human spermatozoa possess a calcium-dependent chloride channel that may participate in the acrosomal reaction.

Orta G, Ferreira G, José O, Treviño CL, Beltrán C, Darszon A.

J Physiol. 2012 Jun 1;590(11):2659-75. doi: 10.1113/jphysiol.2011.224485. Epub 2012 Apr 2.

50.

Flow cytometry analysis reveals a decrease in intracellular sodium during sperm capacitation.

Escoffier J, Krapf D, Navarrete F, Darszon A, Visconti PE.

J Cell Sci. 2012 Jan 15;125(Pt 2):473-85. doi: 10.1242/jcs.093344. Epub 2012 Feb 2.

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