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Items: 50

1.

Mapping of In Vivo RNA-Binding Sites by Ultraviolet (UV)-Cross-Linking Immunoprecipitation (CLIP).

Darnell JC, Mele A, Hung KYS, Darnell RB.

Cold Spring Harb Protoc. 2018 Dec 3;2018(12). doi: 10.1101/pdb.top097931.

PMID:
30510132
2.

Isolation of the RNA Cross-Linking Immunoprecipitation (CLIP) Tags, 5'-Linker Ligation, Reverse Transcription-Polymerase Chain Reaction (RT-PCR) Amplification, and Sequencing.

Darnell JC, Mele A, Hung KYS, Darnell RB.

Cold Spring Harb Protoc. 2018 Dec 3;2018(12). doi: 10.1101/pdb.prot097972.

PMID:
30510128
3.

3'-Linker Ligation and Size Selection by SDS-PAGE for Cross-Linking Immunoprecipitation (CLIP).

Darnell JC, Mele A, Hung KYS, Darnell RB.

Cold Spring Harb Protoc. 2018 Dec 3;2018(12). doi: 10.1101/pdb.prot097964.

PMID:
30510127
4.

Immunoprecipitation and SDS-PAGE for Cross-Linking Immunoprecipitation (CLIP).

Darnell JC, Mele A, Hung KYS, Darnell RB.

Cold Spring Harb Protoc. 2018 Dec 3;2018(12). doi: 10.1101/pdb.prot097956.

PMID:
30510126
5.

Ultraviolet (UV) Cross-Linking of Live Cells, Lysate Preparation, and RNase Titration for Cross-Linking Immunoprecipitation (CLIP).

Darnell JC, Mele A, Hung KYS, Darnell RB.

Cold Spring Harb Protoc. 2018 Dec 3;2018(12). doi: 10.1101/pdb.prot097949.

PMID:
30510125
6.

Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons.

Yuan Y, Xie S, Darnell JC, Darnell AJ, Saito Y, Phatnani H, Murphy EA, Zhang C, Maniatis T, Darnell RB.

Genome Biol. 2018 Aug 15;19(1):117. doi: 10.1186/s13059-018-1493-2.

7.

Feasibility of clinical pharmacist-led CYP2C19 genotyping for patients receiving non-emergent cardiac catheterization in an integrated health system.

Johnson SG, Shaw PB, Delate T, Kurz DL, Gregg D, Darnell JC, Aquilante CL.

Pharm Pract (Granada). 2017 Apr-Jun;15(2):946. doi: 10.18549/PharmPract.2017.02.946. Epub 2017 Jun 30.

8.

Erratum: Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis.

Moore MJ, Zhang C, Gantman EC, Mele A, Darnell JC, Darnell RB.

Nat Protoc. 2016 Mar;11(3):616. doi: 10.1038/nprot0316-616c. Epub 2016 Feb 25. No abstract available.

PMID:
26914319
9.

Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP.

Vasilyev N, Polonskaia A, Darnell JC, Darnell RB, Patel DJ, Serganov A.

Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):E5391-400. doi: 10.1073/pnas.1515737112. Epub 2015 Sep 15.

10.

Cholesterol levels in fragile X syndrome.

Berry-Kravis E, Levin R, Shah H, Mathur S, Darnell JC, Ouyang B.

Am J Med Genet A. 2015 Feb;167A(2):379-84. doi: 10.1002/ajmg.a.36850. Epub 2014 Nov 25.

11.

Molecular biology. Ribosome rescue and neurodegeneration.

Darnell JC.

Science. 2014 Jul 25;345(6195):378-9. doi: 10.1126/science.1257193. Epub 2014 Jul 24. No abstract available.

PMID:
25061188
12.

Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis.

Moore MJ, Zhang C, Gantman EC, Mele A, Darnell JC, Darnell RB.

Nat Protoc. 2014 Feb;9(2):263-93. doi: 10.1038/nprot.2014.012. Epub 2014 Jan 9. Erratum in: Nat Protoc. 2016 Mar;11(3):616.

13.

The translation of translational control by FMRP: therapeutic targets for FXS.

Darnell JC, Klann E.

Nat Neurosci. 2013 Nov;16(11):1530-6. doi: 10.1038/nn.3379. Epub 2013 Apr 14. Review.

14.

Cytoplasmic RNA-binding proteins and the control of complex brain function.

Darnell JC, Richter JD.

Cold Spring Harb Perspect Biol. 2012 Aug 1;4(8):a012344. doi: 10.1101/cshperspect.a012344. Review.

15.

De novo gene disruptions in children on the autistic spectrum.

Iossifov I, Ronemus M, Levy D, Wang Z, Hakker I, Rosenbaum J, Yamrom B, Lee YH, Narzisi G, Leotta A, Kendall J, Grabowska E, Ma B, Marks S, Rodgers L, Stepansky A, Troge J, Andrews P, Bekritsky M, Pradhan K, Ghiban E, Kramer M, Parla J, Demeter R, Fulton LL, Fulton RS, Magrini VJ, Ye K, Darnell JC, Darnell RB, Mardis ER, Wilson RK, Schatz MC, McCombie WR, Wigler M.

Neuron. 2012 Apr 26;74(2):285-99. doi: 10.1016/j.neuron.2012.04.009.

16.

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.

Darnell JC, Van Driesche SJ, Zhang C, Hung KY, Mele A, Fraser CE, Stone EF, Chen C, Fak JJ, Chi SW, Licatalosi DD, Richter JD, Darnell RB.

Cell. 2011 Jul 22;146(2):247-61. doi: 10.1016/j.cell.2011.06.013.

17.

Defects in translational regulation contributing to human cognitive and behavioral disease.

Darnell JC.

Curr Opin Genet Dev. 2011 Aug;21(4):465-73. doi: 10.1016/j.gde.2011.05.002. Epub 2011 Jul 19. Review.

18.

Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.

Teplova M, Malinina L, Darnell JC, Song J, Lu M, Abagyan R, Musunuru K, Teplov A, Burley SK, Darnell RB, Patel DJ.

Structure. 2011 Jul 13;19(7):930-44. doi: 10.1016/j.str.2011.05.002.

19.

Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction.

Phan AT, Kuryavyi V, Darnell JC, Serganov A, Majumdar A, Ilin S, Raslin T, Polonskaia A, Chen C, Clain D, Darnell RB, Patel DJ.

Nat Struct Mol Biol. 2011 Jun 5;18(7):796-804. doi: 10.1038/nsmb.2064.

20.

A mouse model of the human Fragile X syndrome I304N mutation.

Zang JB, Nosyreva ED, Spencer CM, Volk LJ, Musunuru K, Zhong R, Stone EF, Yuva-Paylor LA, Huber KM, Paylor R, Darnell JC, Darnell RB.

PLoS Genet. 2009 Dec;5(12):e1000758. doi: 10.1371/journal.pgen.1000758. Epub 2009 Dec 11.

21.

Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs.

Darnell JC, Fraser CE, Mostovetsky O, Darnell RB.

Hum Mol Genet. 2009 Sep 1;18(17):3164-77. doi: 10.1093/hmg/ddp255. Epub 2009 Jun 1.

22.

HITS-CLIP yields genome-wide insights into brain alternative RNA processing.

Licatalosi DD, Mele A, Fak JJ, Ule J, Kayikci M, Chi SW, Clark TA, Schweitzer AC, Blume JE, Wang X, Darnell JC, Darnell RB.

Nature. 2008 Nov 27;456(7221):464-9. doi: 10.1038/nature07488. Epub 2008 Nov 2.

23.

FMRP RNA targets: identification and validation.

Darnell JC, Mostovetsky O, Darnell RB.

Genes Brain Behav. 2005 Aug;4(6):341-9. Review.

24.

Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes.

Darnell JC, Fraser CE, Mostovetsky O, Stefani G, Jones TA, Eddy SR, Darnell RB.

Genes Dev. 2005 Apr 15;19(8):903-18. Epub 2005 Apr 1.

25.

Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells.

Stefani G, Fraser CE, Darnell JC, Darnell RB.

J Neurosci. 2004 Aug 18;24(33):7272-6.

26.

The fragile X mental retardation protein, FMRP, recognizes G-quartets.

Darnell JC, Warren ST, Darnell RB.

Ment Retard Dev Disabil Res Rev. 2004;10(1):49-52. Review.

PMID:
14994288
27.

Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function.

Darnell JC, Jensen KB, Jin P, Brown V, Warren ST, Darnell RB.

Cell. 2001 Nov 16;107(4):489-99.

28.

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome.

Brown V, Jin P, Ceman S, Darnell JC, O'Donnell WT, Tenenbaum SA, Jin X, Feng Y, Wilkinson KD, Keene JD, Darnell RB, Warren ST.

Cell. 2001 Nov 16;107(4):477-87.

29.
30.

Tumor-specific killer cells in paraneoplastic cerebellar degeneration.

Albert ML, Darnell JC, Bender A, Francisco LM, Bhardwaj N, Darnell RB.

Nat Med. 1998 Nov;4(11):1321-4.

PMID:
9809559
31.
32.

Medication compliance in elderly outpatients using twice-daily dosing and unit-of-use packaging.

Murray MD, Birt JA, Manatunga AK, Darnell JC.

Ann Pharmacother. 1993 May;27(5):616-21.

PMID:
8347915
33.

Coenzyme A-dependent, ATP-independent acylation of 2-acyl lysophosphatidylinositol in rat liver microsomes.

Darnell JC, Saltiel AR.

Biochim Biophys Acta. 1991 Jul 30;1084(3):292-9.

PMID:
1888777
34.

Fatty acid remodelling of phosphatidylinositol under conditions of de novo synthesis in rat liver microsomes.

Darnell JC, Osterman DG, Saltiel AR.

Biochim Biophys Acta. 1991 Jul 30;1084(3):279-91.

PMID:
1888776
35.

Synthesis of phosphatidylinositol in rat liver microsomes is accompanied by the rapid formation of lysophosphatidylinositol.

Darnell JC, Osterman DG, Saltiel AR.

Biochim Biophys Acta. 1991 Jul 30;1084(3):269-78.

PMID:
1888775
36.

Depressive symptoms among elderly residents of public housing: a follow-up study.

Gachaw G, Hendrie HC, Brittain H, Hall KS, Weinberger M, Darnell JC.

Hosp Community Psychiatry. 1991 Jan;42(1):82-4. No abstract available.

PMID:
2026412
37.

The distribution of glycosyl-phosphatidylinositol anchored proteins is differentially regulated by serum and insulin.

Lisanti MP, Darnell JC, Chan BL, Rodriguez-Boulan E, Saltiel AR.

Biochem Biophys Res Commun. 1989 Oct 31;164(2):824-32.

PMID:
2530980
38.

The role of glycosylphosphoinositides in signal transduction.

Saltiel AR, Osterman DG, Darnell JC, Chan BL, Sorbara-Cazan LR.

Recent Prog Horm Res. 1989;45:353-79; discussion 379-82. Review. No abstract available.

PMID:
2682844
39.

The function of glycosyl phosphoinositides in hormone action.

Saltiel AR, Osterman DG, Darnell JC, Sorbara-Cazan LR, Chan BL, Low MG, Cuatrecasas P.

Philos Trans R Soc Lond B Biol Sci. 1988 Jul 26;320(1199):345-58. Review.

PMID:
2906143
40.

A model for predicting depression in elderly tenants of public housing.

Bojrab SL, Sipes GP, Weinberger M, Hendrie HC, Hayes JR, Darnell JC, Martz BL.

Hosp Community Psychiatry. 1988 Mar;39(3):304-9.

PMID:
3356439
41.

Role of glycosyl phosphoinositides in insulin action.

Saltiel AR, Osterman DG, Darnell JC.

Cold Spring Harb Symp Quant Biol. 1988;53 Pt 2:955-63. No abstract available.

PMID:
2855505
42.

British geriatrics, 1986.

Darnell JC.

Indiana Med. 1987 Apr;80(4):366-8. No abstract available.

PMID:
3584943
43.

Self-rated health as a predictor of hospital admission and nursing home placement in elderly public housing tenants.

Weinberger M, Darnell JC, Tierney WM, Martz BL, Hiner SL, Barker J, Neill PJ.

Am J Public Health. 1986 Apr;76(4):457-9.

44.

The effects of positive and negative life changes on the self-reported health status of elderly adults.

Weinberger M, Darnell JC, Martz BL, Hiner SL, Neill PC, Tierney WM.

J Gerontol. 1986 Jan;41(1):114-9.

PMID:
3941249
45.

Medication use by ambulatory elderly. An in-home survey.

Darnell JC, Murray MD, Martz BL, Weinberger M.

J Am Geriatr Soc. 1986 Jan;34(1):1-4.

PMID:
3941238
46.

After-hours telephone access to physicians with access to computerized medical records. Experience in an inner-city general medicine clinic.

Darnell JC, Hiner SL, Neill PJ, Mamlin JJ, McDonald CJ, Hui SL, Tierney WM.

Med Care. 1985 Jan;23(1):20-6.

PMID:
3968920
47.

Recurrent postictal pulmonary edema: a case report and review of the literature.

Darnell JC, Jay SJ.

Epilepsia. 1982 Feb;23(1):71-83.

PMID:
6799285
48.

Primary meningococcal pneumonia: a report of three cases.

Darnell JC, Brandt MJ.

J Indiana State Med Assoc. 1981 Dec;74(12):794-8. Review. No abstract available.

PMID:
6801145
49.

Letter: Blue hands and pseudocyanosis.

Darnell JC.

Ann Intern Med. 1976 May;84(5):617. No abstract available.

PMID:
1275382
50.

Acute epiglottitis in adults--report of a case and review of the literature.

Darnell JC.

J Indiana State Med Assoc. 1976 Jan;69(1):21-3. No abstract available.

PMID:
1249430

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