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Readmission rates following esophageal cancer resection are similar at regionalized and non-regionalized centers: A population-based cohort study.

Gupta V, Bubis L, Kidane B, Mahar AL, Ringash J, Sutradhar R, Darling GE, Coburn NG.

J Thorac Cardiovasc Surg. 2019 May 3. pii: S0022-5223(19)30960-2. doi: 10.1016/j.jtcvs.2019.04.061. [Epub ahead of print]


Neoadjuvant therapy versus upfront surgery for clinical T2N0 esophageal cancer: A systematic review.

Kidane B, Korst RJ, Weksler B, Farrell A, Darling GE, Martin LW, Reddy R, Sarkaria IS.

Ann Thorac Surg. 2019 May 8. pii: S0003-4975(19)30631-9. doi: 10.1016/j.athoracsur.2019.04.008. [Epub ahead of print] Review.


Impact of a novel prioritization framework on clinician-led oncology drug submissions.

Keech J, Beca J, Eisen A, Kennedy E, Kim J, Kouroukis CT, Darling G, Ferguson SE, Finelli A, Petrella TM, Perry JR, Chan K, Gavura S.

Curr Oncol. 2019 Apr;26(2):e155-e161. doi: 10.3747/co.26.4501. Epub 2019 Apr 1.


How equitable is access to treatment for lung cancer patients? A population-based review of treatment practices in Ontario.

Evans WK, Stiff J, Woltman KJ, Ung YC, Su-Myat S, Manivong P, Tsang K, Nazen-Rad N, Gatto A, Tyrrell A, Anas R, Darling G, Sawka C.

Lung Cancer Manag. 2017 Dec;6(3):77-86. doi: 10.2217/lmt-2017-0013. Epub 2017 Dec 1.


Chemical control of structure and guest uptake by a conformationally mobile porous material.

Katsoulidis AP, Antypov D, Whitehead GFS, Carrington EJ, Adams DJ, Berry NG, Darling GR, Dyer MS, Rosseinsky MJ.

Nature. 2019 Jan;565(7738):213-217. doi: 10.1038/s41586-018-0820-9. Epub 2019 Jan 9.


Development and evaluation of screening dysphagia tools for observational studies and routine care in cancer patients.

Borean M, Shani K, Brown MC, Chen J, Liang M, Karkada J, Kooner S, Doherty MK, O'Kane GM, Jang R, Elimova E, Wong RK, Darling GE, Xu W, Howell D, Liu G.

Health Sci Rep. 2018 May 21;1(7):e48. doi: 10.1002/hsr2.48. eCollection 2018 Jul.


Outcomes by treatment modality in elderly patients with localized gastric and esophageal cancer.

Natori A, Chan BA, Sim HW, Ma L, Yokom DW, Chen E, Liu G, Darling G, Swallow C, Brar S, Brierley J, Ringash J, Wong R, Kim J, Rogalla P, Hafezi-Bakhtiari S, Conner J, Knox J, Elimova E, Jang RW.

Curr Oncol. 2018 Dec;25(6):366-370. doi: 10.3747/co.25.4208. Epub 2018 Dec 1.


Structure determination and crystal chemistry of large repeat mixed-layer hexaferrites.

Delacotte C, Whitehead GFS, Pitcher MJ, Robertson CM, Sharp PM, Dyer MS, Alaria J, Claridge JB, Darling GR, Allan DR, Winter G, Rosseinsky MJ.

IUCrJ. 2018 Sep 12;5(Pt 6):681-698. doi: 10.1107/S2052252518011351. eCollection 2018 Nov 1.


Perioperative mortality and morbidity after sublobar versus lobar resection for early-stage non-small-cell lung cancer: post-hoc analysis of an international, randomised, phase 3 trial (CALGB/Alliance 140503).

Altorki NK, Wang X, Wigle D, Gu L, Darling G, Ashrafi AS, Landrenau R, Miller D, Liberman M, Jones DR, Keenan R, Conti M, Wright G, Veit LJ, Ramalingam SS, Kamel M, Pass HI, Mitchell JD, Stinchcombe T, Vokes E, Kohman LJ.

Lancet Respir Med. 2018 Dec;6(12):915-924. doi: 10.1016/S2213-2600(18)30411-9. Epub 2018 Nov 12.


Frailty assessment prior to thoracic surgery for lung or esophageal cancer: a feasibility study.

Hirpara DH, Kidane B, Rogalla P, Cypel M, de Perrot M, Keshavjee S, Pierre A, Waddell T, Yasufuku K, Darling GE.

Support Care Cancer. 2019 Apr;27(4):1535-1540. doi: 10.1007/s00520-018-4547-9. Epub 2018 Nov 14.


Metachronous or synchronous primary lung cancer in the era of computed tomography surveillance.

Wang Y, Yeung JC, Hanna WC, Allison F, Paul NS, Waddell TK, Cypel M, de Perrot ME, Yasufuku K, Keshavjee S, Pierre AF, Darling GE.

J Thorac Cardiovasc Surg. 2018 Oct 6. pii: S0022-5223(18)32556-X. doi: 10.1016/j.jtcvs.2018.09.052. [Epub ahead of print]


Transdiaphragmatic Gastroventricular Fistula.

Carroll PA, Kinsella A, Darling G, Ouzounian M, Yeung JC.

Ann Thorac Surg. 2019 May;107(5):e329-e331. doi: 10.1016/j.athoracsur.2018.09.026. Epub 2018 Oct 31.


Ice Nucleation on a Corrugated Surface.

Lin C, Corem G, Godsi O, Alexandrowicz G, Darling GR, Hodgson A.

J Am Chem Soc. 2018 Nov 21;140(46):15804-15811. doi: 10.1021/jacs.8b08796. Epub 2018 Nov 8.


Emergency department use is high after esophagectomy and feeding tube problems are the biggest culprit.

Kidane B, Kaaki S, Hirpara DH, Shen YC, Bassili A, Allison F, Waddell TK, Darling GE.

J Thorac Cardiovasc Surg. 2018 Dec;156(6):2340-2348. doi: 10.1016/j.jtcvs.2018.07.100. Epub 2018 Sep 7.


Multimodality Therapy for N2 Non-Small Cell Lung Cancer: An Evolving Paradigm.

Spicer JD, Shewale JB, Nelson DB, Mitchell KG, Bott MJ, Vallières E, Wilshire CL, Vaporciyan AA, Swisher SG, Jones DR, Darling GE, Sepesi B.

Ann Thorac Surg. 2019 Jan;107(1):277-284. doi: 10.1016/j.athoracsur.2018.07.033. Epub 2018 Sep 15.


Computational Prediction and Experimental Realization of p-Type Carriers in the Wide-Band-Gap Oxide SrZn1- xLi xO2.

Tzitzeklis CA, Gupta JK, Dyer MS, Manning TD, Pitcher MJ, Niu HJ, Savvin S, Alaria J, Darling GR, Claridge JB, Rosseinsky MJ.

Inorg Chem. 2018 Oct 1;57(19):11874-11883. doi: 10.1021/acs.inorgchem.8b00697. Epub 2018 Sep 10.


Tumor Platinum Concentrations and Pathological Responses Following Cisplatin-Containing Chemotherapy in Gastric Cancer Patients.

Cao Y, Chang Q, Cabanero M, Zhang W, Hafezi-Bakhtiari S, Hedley D, Darling G, Quereshy F, Jang R, Elimova E, Knox J, Ornatsky O, Serra S, Chen E.

J Gastrointest Cancer. 2018 Aug 16. doi: 10.1007/s12029-018-0153-9. [Epub ahead of print]


Health-related quality of life measure distinguishes between low and high clinical T stages in esophageal cancer.

Kidane B, Ali A, Sulman J, Wong R, Knox JJ, Darling GE.

Ann Transl Med. 2018 Jul;6(13):270. doi: 10.21037/atm.2018.06.03.


The role of endobronchial ultrasound-guided transbronchial needle aspiration in stereotactic body radiation therapy for non-small cell lung cancer.

Hashimoto K, Daddi N, Giuliani M, Hope A, Le LW, Czarnecka K, Cypel M, Pierre A, de Perrot M, Darling G, Waddell TK, Keshavjee S, Yasufuku K.

Lung Cancer. 2018 Sep;123:1-6. doi: 10.1016/j.lungcan.2018.06.011. Epub 2018 Jun 11.


The Flexible Unit Structure Engine (FUSE) for probe structure-based composition prediction.

Collins C, Darling GR, Rosseinsky MJ.

Faraday Discuss. 2018 Oct 26;211(0):117-131. doi: 10.1039/c8fd00045j.


Survival prediction tools for esophageal and gastroesophageal junction cancer: A systematic review.

Gupta V, Coburn N, Kidane B, Hess KR, Compton C, Ringash J, Darling G, Mahar AL.

J Thorac Cardiovasc Surg. 2018 Aug;156(2):847-856. doi: 10.1016/j.jtcvs.2018.03.146. Epub 2018 Apr 12.


Guideline for the Initial Management of Small Cell Lung Cancer (Limited and Extensive Stage) and the Role of Thoracic Radiotherapy and First-line Chemotherapy.

Sun A, Durocher-Allen LD, Ellis PM, Ung YC, Goffin JR, Ramchandar K, Darling G.

Clin Oncol (R Coll Radiol). 2018 Oct;30(10):658-666. doi: 10.1016/j.clon.2018.06.008. Epub 2018 Jul 11.


Health utility scores from EQ-5D and health-related quality of life in patients with esophageal cancer: a real-world cross-sectional study.

Doherty MK, Leung Y, Su J, Naik H, Patel D, Eng L, Kong QQ, Mohsin F, Brown MC, Espin-Garcia O, Vennettilli A, Renouf DJ, Faluyi OO, Knox JJ, MacKay H, Wong R, Howell D, Mittmann N, Darling GE, Cella D, Xu W, Liu G.

Dis Esophagus. 2018 Dec 1;31(12). doi: 10.1093/dote/doy058.


Hedgehog inhibition mediates radiation sensitivity in mouse xenograft models of human esophageal adenocarcinoma.

Teichman J, Dodbiba L, Thai H, Fleet A, Morey T, Liu L, McGregor M, Cheng D, Chen Z, Darling G, Brhane Y, Song Y, Espin-Garcia O, Xu W, Girgis H, Schwock J, MacKay H, Bristow R, Ailles L, Liu G.

PLoS One. 2018 May 1;13(5):e0194809. doi: 10.1371/journal.pone.0194809. eCollection 2018.


Quality of life assessment in esophagectomy patients.

Alghamedi A, Buduhan G, Tan L, Srinathan SK, Sulman J, Darling G, Kidane B.

Ann Transl Med. 2018 Feb;6(4):84. doi: 10.21037/atm.2017.11.38. Review.


Medium and long-term emergency department utilization after oesophagectomy: a population-based analysis.

Kidane B, Jacob B, Gupta V, Peel J, Saskin R, Waddell TK, Darling GE.

Eur J Cardiothorac Surg. 2018 Oct 1;54(4):683-688. doi: 10.1093/ejcts/ezy155.


miR-145 expression enhances integrin expression in SK-GT-4 cell line by down-regulating c-Myc expression.

Derouet MF, Dakpo E, Wu L, Zehong G, Conner J, Keshavjee S, de Perrot M, Waddell T, Elimova E, Yeung J, Darling GE.

Oncotarget. 2018 Mar 8;9(20):15198-15207. doi: 10.18632/oncotarget.24613. eCollection 2018 Mar 16.


Efficacy and Cost of Awake Thoracoscopy and Video-Assisted Thoracoscopic Surgery in the Undiagnosed Pleural Effusion.

McDonald CM, Pierre C, de Perrot M, Darling G, Cypel M, Pierre A, Waddell T, Keshavjee S, Yasufuku K, Czarnecka-Kujawa K.

Ann Thorac Surg. 2018 Aug;106(2):361-367. doi: 10.1016/j.athoracsur.2018.02.044. Epub 2018 Mar 22.


Two-Dimensional Wetting of a Stepped Copper Surface.

Lin C, Avidor N, Corem G, Godsi O, Alexandrowicz G, Darling GR, Hodgson A.

Phys Rev Lett. 2018 Feb 16;120(7):076101. doi: 10.1103/PhysRevLett.120.076101.


Well-Differentiated Liposarcoma (Atypical Lipomatous Tumor) Presenting as an Esophageal Polyp.

McCarthy AJ, Carroll P, Vajpeyi R, Darling G, Chetty R.

J Gastrointest Cancer. 2018 Jan 19. doi: 10.1007/s12029-018-0052-0. [Epub ahead of print] No abstract available.


Complete mediastinal lymph node dissection versus systematic lymph node sampling in surgical treatment of non-small cell lung cancer: do we have the answer?

Wang Y, Darling GE.

J Thorac Dis. 2017 Nov;9(11):4169-4170. doi: 10.21037/jtd.2017.10.39. No abstract available.


Benchmarking Complications Associated with Esophagectomy.

Low DE, Kuppusamy MK, Alderson D, Cecconello I, Chang AC, Darling G, Davies A, D'Journo XB, Gisbertz SS, Griffin SM, Hardwick R, Hoelscher A, Hofstetter W, Jobe B, Kitagawa Y, Law S, Mariette C, Maynard N, Morse CR, Nafteux P, Pera M, Pramesh CS, Puig S, Reynolds JV, Schroeder W, Smithers M, Wijnhoven BPL.

Ann Surg. 2019 Feb;269(2):291-298. doi: 10.1097/SLA.0000000000002611.


Surgical Treatment for Early Small Cell Lung Cancer: Variability in Practice and Impact on Survival.

Wakeam E, Byrne JP, Darling GE, Varghese TK Jr.

Ann Thorac Surg. 2017 Dec;104(6):1872-1880. doi: 10.1016/j.athoracsur.2017.07.009. Epub 2017 Oct 26.


National practice variation in pneumonectomy perioperative care among Canadian thoracic surgeons.

Kidane B, Peel JK, Seely A, Malthaner RA, Finley C, Grondin S, Louie BE, Srinathan S, Darling GE.

Interact Cardiovasc Thorac Surg. 2017 Dec 1;25(6):872-876. doi: 10.1093/icvts/ivx252.


Performance of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for the Diagnosis of Isolated Mediastinal and Hilar Lymphadenopathy.

Tyan CC, Machuca T, Czarnecka K, Ko HM, da Cunha Santos G, Boerner SL, Pierre A, Cypel M, Waddell T, Darling G, de Perrot M, Keshavjee S, Geddie W, Yasufuku K.

Respiration. 2017;94(5):457-464. doi: 10.1159/000479745. Epub 2017 Sep 13.


Development of a novel ex vivo porcine laparoscopic Heller myotomy and Nissen fundoplication training model (Toronto lap-Nissen simulator).

Ujiie H, Kato T, Hu HP, Bauer P, Patel P, Wada H, Lee D, Fujino K, Schieman C, Pierre A, Waddell TK, Keshavjee S, Darling GE, Yasufuku K.

J Thorac Dis. 2017 Jun;9(6):1517-1524. doi: 10.21037/jtd.2017.05.84.


Regionalization and Outcomes of Lung Cancer Surgery in Ontario, Canada.

Bendzsak AM, Baxter NN, Darling GE, Austin PC, Urbach DR.

J Clin Oncol. 2017 Aug 20;35(24):2772-2780. doi: 10.1200/JCO.2016.69.8076. Epub 2017 Jul 6.


Accelerated discovery of two crystal structure types in a complex inorganic phase field.

Collins C, Dyer MS, Pitcher MJ, Whitehead GFS, Zanella M, Mandal P, Claridge JB, Darling GR, Rosseinsky MJ.

Nature. 2017 Jun 7;546(7657):280-284. doi: 10.1038/nature22374.


Surgery Versus Chemotherapy and Radiotherapy For Early and Locally Advanced Small Cell Lung Cancer: A Propensity-Matched Analysis of Survival.

Wakeam E, Acuna SA, Leighl NB, Giuliani ME, Finlayson SRG, Varghese TK, Darling GE.

Lung Cancer. 2017 Jul;109:78-88. doi: 10.1016/j.lungcan.2017.04.021. Epub 2017 May 1.


Trends, practice patterns and underuse of surgery in the treatment of early stage small cell lung cancer.

Wakeam E, Varghese TK Jr, Leighl NB, Giuliani M, Finlayson SRG, Darling GE.

Lung Cancer. 2017 Jul;109:117-123. doi: 10.1016/j.lungcan.2017.05.004. Epub 2017 May 13.


A novel minimally invasive near-infrared thoracoscopic localization technique of small pulmonary nodules: A phase I feasibility trial.

Ujiie H, Kato T, Hu HP, Patel P, Wada H, Fujino K, Weersink R, Nguyen E, Cypel M, Pierre A, de Perrot M, Darling G, Waddell TK, Keshavjee S, Yasufuku K.

J Thorac Cardiovasc Surg. 2017 Aug;154(2):702-711. doi: 10.1016/j.jtcvs.2017.03.140. Epub 2017 Apr 13.


Association of BRM promoter polymorphisms and esophageal adenocarcinoma outcome.

Korpanty GJ, Eng L, Qiu X, Faluyi OO, Renouf DJ, Cheng D, Patel D, Chen Z, Tse BC, Knox JJ, Dodbiba L, Teichman J, Azad AK, Wong R, Darling G, Reisman D, Cuffe S, Liu G, Xu W.

Oncotarget. 2017 Apr 25;8(17):28093-28100. doi: 10.18632/oncotarget.15890.


TOPGEAR: A Randomized, Phase III Trial of Perioperative ECF Chemotherapy with or Without Preoperative Chemoradiation for Resectable Gastric Cancer: Interim Results from an International, Intergroup Trial of the AGITG, TROG, EORTC and CCTG.

Leong T, Smithers BM, Haustermans K, Michael M, Gebski V, Miller D, Zalcberg J, Boussioutas A, Findlay M, O'Connell RL, Verghis J, Willis D, Kron T, Crain M, Murray WK, Lordick F, Swallow C, Darling G, Simes J, Wong R.

Ann Surg Oncol. 2017 Aug;24(8):2252-2258. doi: 10.1245/s10434-017-5830-6. Epub 2017 Mar 23.


Cost-effectiveness of mediastinal lymph node staging in non-small cell lung cancer.

Czarnecka-Kujawa K, Rochau U, Siebert U, Atenafu E, Darling G, Waddell TK, Pierre A, De Perrot M, Cypel M, Keshavjee S, Yasufuku K.

J Thorac Cardiovasc Surg. 2017 Jun;153(6):1567-1578. doi: 10.1016/j.jtcvs.2016.12.048. Epub 2017 Feb 9.


Indications for Adjuvant Mediastinal Radiotherapy in Surgically Resected Small Cell Lung Cancer.

Wakeam E, Giuliani M, Leighl NB, Finlayson SRG, Varghese TK, Darling GE.

Ann Thorac Surg. 2017 May;103(5):1647-1653. doi: 10.1016/j.athoracsur.2016.11.039. Epub 2017 Mar 3.


Invasive Mediastinal Staging Guideline Concordance.

Bendzsak A, Waddell TK, Yasufuku K, Keshavjee S, de Perrot M, Cypel M, Pierre AF, Darling GE.

Ann Thorac Surg. 2017 Jun;103(6):1736-1741. doi: 10.1016/j.athoracsur.2016.12.010. Epub 2017 Mar 3.


High Risk for Thoracotomy but not Thoracoscopic Lobectomy.

Donahoe LL, de Valence M, Atenafu EG, Hanna WC, Waddell TK, Pierre AF, Yasufuku K, de Perrot M, Cypel M, Keshavjee S, Darling GE.

Ann Thorac Surg. 2017 Jun;103(6):1730-1735. doi: 10.1016/j.athoracsur.2016.11.076. Epub 2017 Mar 3.


Chiral segregation driven by a dynamical response of the adsorption footprint to the local adsorption environment: bitartrate on Cu(110).

Darling GR, Forster M, Lin C, Liu N, Raval R, Hodgson A.

Phys Chem Chem Phys. 2017 Mar 15;19(11):7617-7623. doi: 10.1039/c7cp00622e.


Early adulthood body mass index, cumulative smoking, and esophageal adenocarcinoma survival.

Spreafico A, Coate L, Zhai R, Xu W, Chen ZF, Chen Z, Patel D, Tse B, Brown MC, Heist RS, Dodbiba L, Teichman J, Kulke M, Su L, Eng L, Knox J, Wong R, Darling GE, Christiani DC, Liu G.

Cancer Epidemiol. 2017 Apr;47:28-34. doi: 10.1016/j.canep.2016.11.009. Epub 2017 Jan 12.


Validation of microRNA pathway polymorphisms in esophageal adenocarcinoma survival.

Faluyi OO, Eng L, Qiu X, Che J, Zhang Q, Cheng D, Ying N, Tse A, Kuang Q, Dodbiba L, Renouf DJ, Marsh S, Savas S, Mackay HJ, Knox JJ, Darling GE, Wong RK, Xu W, Azad AK, Liu G.

Cancer Med. 2017 Feb;6(2):361-373. doi: 10.1002/cam4.989. Epub 2017 Jan 11.

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