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Items: 1 to 50 of 112

1.

PRION-1 scales analysis supports use of functional outcome measures in prion disease.

Mead S, Ranopa M, Gopalakrishnan GS, Thompson AG, Rudge P, Wroe S, Kennedy A, Hudson F, MacKay A, Darbyshire JH, Collinge J, Walker AS.

Neurology. 2011 Nov 1;77(18):1674-83. doi: 10.1212/WNL.0b013e3182364890. Epub 2011 Oct 19. Erratum in: Neurology. 2012 Jan 31;78(5):371.

2.

Randomised, placebo-controlled trial to evaluate co-trimoxazole to reduce mortality and morbidity in HIV-infected post-natal women in Zambia (TOPAZ).

Nunn AJ, Mwaba PB, Chintu C, Crook AM, Darbyshire JH, Ahmed Y, Zumla AI.

Trop Med Int Health. 2011 Apr;16(4):518-26. doi: 10.1111/j.1365-3156.2011.02731.x. Epub 2011 Feb 1.

3.

Daily co-trimoxazole prophylaxis in severely immunosuppressed HIV-infected adults in Africa started on combination antiretroviral therapy: an observational analysis of the DART cohort.

Walker AS, Ford D, Gilks CF, Munderi P, Ssali F, Reid A, Katabira E, Grosskurth H, Mugyenyi P, Hakim J, Darbyshire JH, Gibb DM, Babiker AG.

Lancet. 2010 Apr 10;375(9722):1278-86. doi: 10.1016/S0140-6736(10)60057-8. Epub 2010 Mar 27.

4.

Nevirapine/zidovudine/lamivudine has superior immunological and virological responses not reflected in clinical outcomes in a 48-week randomized comparison with abacavir/zidovudine/lamivudine in HIV-infected Ugandan adults with low CD4 cell counts.

Munderi P, Walker AS, Kityo C, Babiker AG, Ssali F, Reid A, Darbyshire JH, Grosskurth H, Mugyenyi P, Gibb DM, Gilks CF; DART/NORA trial teams.

HIV Med. 2010 May;11(5):334-44. doi: 10.1111/j.1468-1293.2009.00786.x. Epub 2010 Feb 3.

5.

Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial.

DART Trial Team, Mugyenyi P, Walker AS, Hakim J, Munderi P, Gibb DM, Kityo C, Reid A, Grosskurth H, Darbyshire JH, Ssali F, Bray D, Katabira E, Babiker AG, Gilks CF, Grosskurth H, Munderi P, Kabuye G, Nsibambi D, Kasirye R, Zalwango E, Nakazibwe M, Kikaire B, Nassuna G, Massa R, Fadhiru K, Namyalo M, Zalwango A, Generous L, Khauka P, Rutikarayo N, Nakahima W, Mugisha A, Todd J, Levin J, Muyingo S, Ruberantwari A, Kaleebu P, Yirrell D, Ndembi N, Lyagoba F, Hughes P, Aber M, Lara AM, Foster S, Amurwon J, Wakholi BN, Whitworth J, Wangati K, Amuron B, Kajungu D, Nakiyingi J, Omony W, Fadhiru K, Nsibambi D, Khauka P, Mugyenyi P, Kityo C, Ssali F, Tumukunde D, Otim T, Kabanda J, Musana H, Akao J, Kyomugisha H, Byamukama A, Sabiiti J, Komugyena J, Wavamunno P, Mukiibi S, Drasiku A, Byaruhanga R, Labeja O, Katundu P, Tugume S, Awio P, Namazzi A, Bakeinyaga GT, Katabira H, Abaine D, Tukamushaba J, Anywar W, Ojiambo W, Angweng E, Murungi S, Haguma W, Atwiine S, Kigozi J, Namale L, Mukose A, Mulindwa G, Atwiine D, Muhwezi A, Nimwesiga E, Barungi G, Takubwa J, Murungi S, Mwebesa D, Kagina G, Mulindwa M, Ahimbisibwe F, Mwesigwa P, Akuma S, Zawedde C, Nyiraguhirwa D, Tumusiime C, Bagaya L, Namara W, Kigozi J, Karungi J, Kankunda R, Enzama R, Latif A, Hakim J, Robertson V, Reid A, Chidziva E, Bulaya-Tembo R, Musoro G, Taziwa F, Chimbetete C, Chakonza L, Mawora A, Muvirimi C, Tinago G, Svovanapasis P, Simango M, Chirema O, Machingura J, Mutsai S, Phiri M, Bafana T, Chirara M, Muchabaiwa L, Muzambi M, Mutowo J, Chivhunga T, Chigwedere E, Pascoe M, Warambwa C, Zengeza E, Mapinge F, Makota S, Jamu A, Ngorima N, Chirairo H, Chitsungo S, Chimanzi J, Maweni C, Warara R, Matongo M, Mudzingwa S, Jangano M, Moyo K, Vere L, Mdege N, Machingura I, Katabira E, Ronald A, Kambungu A, Lutwama F, Mambule I, Nanfuka A, Walusimbi J, Nabankema E, Nalumenya R, Namuli T, Kulume R, Namata I, Nyachwo L, Florence A, Kusiima A, Lubwama E, Nairuba R, Oketta F, Buluma E, Waita R, Ojiambo H, Sadik F, Wanyama J, Nabongo P, Oyugi J, Sematala F, Muganzi A, Twijukye C, Byakwaga H, Ochai R, Muhweezi D, Coutinho A, Etukoit B, Gilks C, Boocock K, Puddephatt C, Grundy C, Bohannon J, Winogron D, Gibb DM, Burke A, Bray D, Babiker A, Walker AS, Wilkes H, Rauchenberger M, Sheehan S, Spencer-Drake C, Taylor K, Spyer M, Ferrier A, Naidoo B, Dunn D, Goodall R, Darbyshire JH, Peto L, Nanfuka R, Mufuka-Kapuya C, Kaleebu P, Pillay D, Robertson V, Yirrell D, Tugume S, Chirara M, Katundu P, Ndembi N, Lyagoba F, Dunn D, Goodall R, McCormick A, Lara AM, Foster S, Amurwon J, Wakholi BN, Kigozi J, Muchabaiwa L, Muzambi M, Weller I, Babiker A, Bahendeka S, Bassett M, Wapakhabulo AC, Darbyshire JH, Gazzard B, Gilks C, Grosskurth H, Hakim J, Latif A, Mapuchere C, Mugurungi O, Mugyenyi P, Burke C, Jones S, Newland C, Pearce G, Rahim S, Rooney J, Smith M, Snowden W, Steens JM, Breckenridge A, McLaren A, Hill C, Matenga J, Pozniak A, Serwadda D, Peto T, Palfreeman A, Borok M, Katabira E.

Lancet. 2010 Jan 9;375(9709):123-31. doi: 10.1016/S0140-6736(09)62067-5. Epub 2009 Dec 8.

6.

Estimating glomerular filtration rate in HIV-infected adults in Africa: comparison of Cockcroft-Gault and Modification of Diet in Renal Disease formulae.

Stöhr W, Walker AS, Munderi P, Tugume S, Gilks CF, Darbyshire JH, Hakim J; DART Trial.

Antivir Ther. 2008;13(6):761-70.

PMID:
18839777
7.

Role of co-trimoxazole prophylaxis in reducing mortality in HIV infected adults being treated for tuberculosis: randomised clinical trial.

Nunn AJ, Mwaba P, Chintu C, Mwinga A, Darbyshire JH, Zumla A; UNZA-UCLMS Project LUCOT Collaboration.

BMJ. 2008 Jul 10;337:a257. doi: 10.1136/bmj.a257.

8.

The UK Clinical Research Network--building a world-class infrastructure for clinical research.

Darbyshire JH.

Rheumatology (Oxford). 2008 Jun;47(6):745. doi: 10.1093/rheumatology/ken112. Epub 2008 Apr 14. No abstract available.

PMID:
18411216
9.

Main morbidities recorded in the women's international study of long duration oestrogen after menopause (WISDOM): a randomised controlled trial of hormone replacement therapy in postmenopausal women.

Vickers MR, MacLennan AH, Lawton B, Ford D, Martin J, Meredith SK, DeStavola BL, Rose S, Dowell A, Wilkes HC, Darbyshire JH, Meade TW; WISDOM group.

BMJ. 2007 Aug 4;335(7613):239. Epub 2007 Jul 11.

10.

A virological benefit from an induction/maintenance strategy: the Forte trial.

Asboe D, Williams IG, Goodall RL, Darbyshire JH, Hooker MH, Babiker AG; Forte Steering Committee.

Antivir Ther. 2007;12(1):47-54.

PMID:
17503747
11.

Prevalence, incidence and predictors of severe anaemia with zidovudine-containing regimens in African adults with HIV infection within the DART trial.

Ssali F, Stöhr W, Munderi P, Reid A, Walker AS, Gibb DM, Mugyenyi P, Kityo C, Grosskurth H, Hakim J, Byakwaga H, Katabira E, Darbyshire JH, Gilks CF; DART Trial Team.

Antivir Ther. 2006;11(6):741-9.

PMID:
17310818
12.

The UK Diabetes Research Network--an opportunity and a challenge.

Matthews DR, Kennedy ED, Darbyshire JH, Johnston DG.

Diabet Med. 2007 Jan;24(1):7-9.

PMID:
17227318
13.

Virological and immunological outcomes at 3 years after starting antiretroviral therapy with regimens containing non-nucleoside reverse transcriptase inhibitor, protease inhibitor, or both in INITIO: open-label randomised trial.

INITIO Trial International Co-ordinating Committee, Yeni P, Cooper DA, Aboulker JP, Babiker AG, Carey D, Darbyshire JH, Floridia M, Girard PM, Goodall RL, Hooker MH, Mijch A, Meiffredy V, Salzberger B.

Lancet. 2006 Jul 22;368(9532):287-98.

PMID:
16860698
14.

A randomized controlled trial of the value of phenotypic testing in addition to genotypic testing for HIV drug resistance: evaluation of resistance assays (ERA) trial investigators.

Dunn DT, Green H, Loveday C, Rinehart A, Pillay D, Fisher M, McCormack S, Babiker AG, Darbyshire JH; Evaluation of Resistance Assays (ERA) Trial Investigators.

J Acquir Immune Defic Syndr. 2005 Apr 15;38(5):553-9. Erratum in: J Acquir Immune Defic Syndr. 2005 Jun 1;39(2):255.

PMID:
15793365
15.

Issues in data monitoring and interim analysis of trials.

Grant AM, Altman DG, Babiker AB, Campbell MK, Clemens FJ, Darbyshire JH, Elbourne DR, McLeer SK, Parmar MK, Pocock SJ, Spiegelhalter DJ, Sydes MR, Walker AE, Wallace SA; DAMOCLES study group.

Health Technol Assess. 2005 Mar;9(7):1-238, iii-iv. Review.

16.

U.K. Controlled trial of intrapleural streptokinase for pleural infection.

Maskell NA, Davies CW, Nunn AJ, Hedley EL, Gleeson FV, Miller R, Gabe R, Rees GL, Peto TE, Woodhead MA, Lane DJ, Darbyshire JH, Davies RJ; First Multicenter Intrapleural Sepsis Trial (MIST1) Group.

N Engl J Med. 2005 Mar 3;352(9):865-74. Erratum in: N Engl J Med. 2005 May 19;352(20):2146.

17.

HIV drug resistance testing: is the evidence really there?

Dunn DT, Gibb DM, Babiker AG, Green H, Darbyshire JH, Weller IV.

Antivir Ther. 2004 Oct;9(5):641-8. Review.

PMID:
15535402
18.

A comparison of two methods for the estimation of precision with incomplete longitudinal data, jointly modelled with a time-to-event outcome.

Touloumi G, Babiker AG, Kenward MG, Pocock SJ, Darbyshire JH.

Stat Med. 2003 Oct 30;22(20):3161-75.

PMID:
14518021
19.

Impact of missing data due to selective dropouts in cohort studies and clinical trials.

Touloumi G, Pocock SJ, Babiker AG, Darbyshire JH.

Epidemiology. 2002 May;13(3):347-55.

PMID:
11964938
20.

The evaluation of subcutaneous proleukin (interleukin-2) in a randomized international trial: rationale, design, and methods of ESPRIT.

Emery S, Abrams DI, Cooper DA, Darbyshire JH, Lane HC, Lundgren JD, Neaton JD; ESPRIT Study Group.

Control Clin Trials. 2002 Apr;23(2):198-220.

PMID:
11943448
21.

Impact of missing data due to drop-outs on estimators for rates of change in longitudinal studies: a simulation study.

Touloumi G, Babiker AG, Pocock SJ, Darbyshire JH.

Stat Med. 2001 Dec 30;20(24):3715-28.

PMID:
11782028
22.

Age as a determinant of survival in HIV infection.

Babiker AG, Peto T, Porter K, Walker AS, Darbyshire JH.

J Clin Epidemiol. 2001 Dec;54 Suppl 1:S16-21.

PMID:
11750205
23.

Tuberculosis at the end of the 20th century in England and Wales: results of a national survey in 1998.

Rose AM, Watson JM, Graham C, Nunn AJ, Drobniewski F, Ormerod LP, Darbyshire JH, Leese J; Public Health Laboratory Service/British Thoracic Society/Department of Health Collaborative Group.

Thorax. 2001 Mar;56(3):173-9. Erratum in: Thorax 2001 Jun;56(6):504.

24.

Analysis of multivariate failure-time data from HIV clinical trials.

Walker AS, Babiker AG, Darbyshire JH.

Control Clin Trials. 2000 Apr;21(2):75-93.

PMID:
10715506
25.
26.

Randomization-based methods for correcting for treatment changes: examples from the Concorde trial.

White IR, Babiker AG, Walker S, Darbyshire JH.

Stat Med. 1999 Oct 15;18(19):2617-34.

PMID:
10495460
27.

Estimation and comparison of rates of change in longitudinal studies with informative drop-outs.

Touloumi G, Pocock SJ, Babiker AG, Darbyshire JH.

Stat Med. 1999 May 30;18(10):1215-33.

PMID:
10363341
28.

Markers of HIV infection in the Concorde trial. Concorde Co-ordinating Committee.

Walker AS, Peto TE, Babiker AG, Darbyshire JH.

QJM. 1998 Jun;91(6):423-38.

PMID:
9709461
30.

Comparison of culture- and non-culture-based methods for quantification of viral load and resistance to antiretroviral drugs in patients given zidovudine monotherapy.

Tedder RS, Kaye S, Loveday C, Weller IV, Jeffries D, Norman J, Weber J, Bourelly M, Foxall R, Babiker A, Darbyshire JH.

J Clin Microbiol. 1998 Apr;36(4):1056-63.

31.

Reporting adverse drug reactions in HIV infection.

Arlett PR, Lee EH, Hooker M, Darbyshire JH, Breckenridge AM.

Genitourin Med. 1997 Oct;73(5):335. No abstract available.

33.

Tuberculosis--an epidemic of injustice.

Darbyshire JH.

J R Coll Physicians Lond. 1998 Jan-Feb;32(1):84. No abstract available.

PMID:
9507449
34.

Impact of treatment changes on the interpretation of the Concorde trial.

White IR, Walker S, Babiker AG, Darbyshire JH.

AIDS. 1997 Jul;11(8):999-1006.

PMID:
9223734
35.

Antiretroviral drug trials.

Breckenridge A, Kitchen V, Darbyshire JH.

Science. 1997 Jun 6;276(5318):1481-2; author reply 1443-4. No abstract available.

PMID:
9190678
36.

Are healthcare workers in England and Wales at increased risk of tuberculosis?

Meredith S, Watson JM, Citron KM, Cockcroft A, Darbyshire JH.

BMJ. 1996 Aug 31;313(7056):522-5.

37.

Treatment of children with HIV infection. PENTA (Paediatric European Network for Treatment of AIDS)

Gibb DM, Darbyshire JH, Debré M, Giaquinto C, Aboulker JP, Martinez M, Tudor-Williams G.

Lancet. 1995 Apr 29;345(8957):1115. No abstract available.

PMID:
7715361
38.

Tuberculosis: old reasons for a new increase?

Darbyshire JH.

BMJ. 1995 Apr 15;310(6985):954-5. No abstract available.

39.

Tuberculosis and HIV: estimates of the overlap in England and Wales.

Watson JM, Meredith SK, Whitmore-Overton E, Bannister B, Darbyshire JH.

Thorax. 1993 Mar;48(3):199-203.

40.

Didanosine for zidovudine-intolerant patients with HIV disease.

Darbyshire JH, Aboulker JP.

Lancet. 1992 Nov 28;340(8831):1346-7. No abstract available.

PMID:
1360049
41.

Patterns of tuberculosis in Indian and Pakistani/Bangladeshi patients: effects of age, date of first entry and ethnic group.

Ormerod LP, Nunn AJ, Byfield SP, Darbyshire JH.

Respir Med. 1991 Jul;85(4):275-80.

PMID:
1947363
42.

HIV infection and tuberculosis.

Darbyshire JH.

Q J Med. 1991 Jul;80(291):563-4. No abstract available.

PMID:
1946936
43.

Six year follow up of lung function in men occupationally exposed to formaldehyde.

Nunn AJ, Craigen AA, Darbyshire JH, Venables KM, Newman Taylor AJ.

Br J Ind Med. 1990 Nov;47(11):747-52.

44.

Short course chemotherapy for pulmonary tuberculosis in routine service in Kenya.

Babu Swai O, Aluoch JA, Githui W, Darbyshire JH.

East Afr Med J. 1990 Nov;67(11):748-55.

PMID:
2076674
45.

Early HIV infection: to treat or not to treat?

Swart AM, Weller I, Darbyshire JH.

BMJ. 1990 Oct 13;301(6756):825-6. No abstract available.

46.

Double-blind randomized study of prolonged higher-dose oral amoxycillin in purulent bronchiectasis.

Currie DC, Garbett ND, Chan KL, Higgs E, Todd H, Chadwick MV, Gaya H, Nunn AJ, Darbyshire JH, Cole PJ.

Q J Med. 1990 Aug;76(280):799-816.

PMID:
2217684
47.

Controlled trial of natamycin in the treatment of allergic bronchopulmonary aspergillosis.

Currie DC, Lueck C, Milburn HJ, Harvey C, Longbottom JL, Darbyshire JH, Nunn AJ, Cole PJ.

Thorax. 1990 Jun;45(6):447-50.

48.

Tuberculosis in prisons.

Darbyshire JH.

BMJ. 1989 Oct 7;299(6704):874. Review. No abstract available.

49.
50.

Changes in tuberculosis notification rates in the white ethnic group in England and Wales between 1953 and 1983.

Springett VH, Darbyshire JH, Nunn AJ, Sutherland I.

J Epidemiol Community Health. 1988 Dec;42(4):370-6.

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