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Items: 17

1.

Siplizumab selectively depletes effector memory T cells and promotes a relative expansion of alloreactive regulatory T cells in vitro.

Podestà MA, Binder C, Sellberg F, DeWolf S, Shonts B, Ho SH, Obradovic A, Waffarn E, Danzl N, Berglund D, Sykes M.

Am J Transplant. 2019 Jul 18. doi: 10.1111/ajt.15533. [Epub ahead of print]

PMID:
31319439
2.

Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro.

Luchsinger LL, Strikoudis A, Danzl NM, Bush EC, Finlayson MO, Satwani P, Sykes M, Yazawa M, Snoeck HW.

Cell Stem Cell. 2019 Aug 1;25(2):225-240.e7. doi: 10.1016/j.stem.2019.05.002. Epub 2019 Jun 6.

PMID:
31178255
3.

Crossreactive public TCR sequences undergo positive selection in the human thymic repertoire.

Khosravi-Maharlooei M, Obradovic A, Misra A, Motwani K, Holzl M, Seay HR, DeWolf S, Nauman G, Danzl N, Li H, Ho SH, Winchester R, Shen Y, Brusko TM, Sykes M.

J Clin Invest. 2019 Mar 28;129(6):2446-2462. doi: 10.1172/JCI124358.

4.

Posttransplant Hemophagocytic Lymphohistiocytosis Driven by Myeloid Cytokines and Vicious Cycles of T-Cell and Macrophage Activation in Humanized Mice.

Yoshihara S, Li Y, Xia J, Danzl N, Sykes M, Yang YG.

Front Immunol. 2019 Feb 13;10:186. doi: 10.3389/fimmu.2019.00186. eCollection 2019.

5.

HSC extrinsic sex-related and intrinsic autoimmune disease-related human B-cell variation is recapitulated in humanized mice.

Borsotti C, Danzl NM, Nauman G, Hölzl MA, French C, Chavez E, Khosravi-Maharlooei M, Glauzy S, Delmotte FR, Meffre E, Savage DG, Campbell SR, Goland R, Greenberg E, Bi J, Satwani P, Yang S, Bathon J, Winchester R, Sykes M.

Blood Adv. 2017 Oct 13;1(23):2007-2018. doi: 10.1182/bloodadvances.2017006932. eCollection 2017 Oct 24.

6.

β-Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells.

Sui L, Danzl N, Campbell SR, Viola R, Williams D, Xing Y, Wang Y, Phillips N, Poffenberger G, Johannesson B, Oberholzer J, Powers AC, Leibel RL, Chen X, Sykes M, Egli D.

Diabetes. 2018 Jan;67(1):26-35. doi: 10.2337/db17-0120. Epub 2017 Sep 20.

7.

Type 1 diabetes induction in humanized mice.

Tan S, Li Y, Xia J, Jin CH, Hu Z, Duinkerken G, Li Y, Khosravi Maharlooei M, Chavez E, Nauman G, Danzl N, Nakayama M, Roep BO, Sykes M, Yang YG.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10954-10959. doi: 10.1073/pnas.1710415114. Epub 2017 Sep 5.

8.

Identification of novel thymic epithelial cell subsets whose differentiation is regulated by RANKL and Traf6.

Danzl NM, Jeong S, Choi Y, Alexandropoulos K.

PLoS One. 2014 Jan 21;9(1):e86129. doi: 10.1371/journal.pone.0086129. eCollection 2014. Erratum in: PLoS One. 2014;9(10):e110921.

9.

Medullary thymic epithelial cell depletion leads to autoimmune hepatitis.

Bonito AJ, Aloman C, Fiel MI, Danzl NM, Cha S, Weinstein EG, Jeong S, Choi Y, Walsh MC, Alexandropoulos K.

J Clin Invest. 2013 Aug;123(8):3510-24. doi: 10.1172/JCI65414. Epub 2013 Jul 15.

10.

Thymic epithelial cells: antigen presenting cells that regulate T cell repertoire and tolerance development.

Alexandropoulos K, Danzl NM.

Immunol Res. 2012 Dec;54(1-3):177-90. doi: 10.1007/s12026-012-8301-y. Review.

PMID:
22454100
11.

A model for personalized in vivo analysis of human immune responsiveness.

Kalscheuer H, Danzl N, Onoe T, Faust T, Winchester R, Goland R, Greenberg E, Spitzer TR, Savage DG, Tahara H, Choi G, Yang YG, Sykes M.

Sci Transl Med. 2012 Mar 14;4(125):125ra30. doi: 10.1126/scitranslmed.3003481.

12.

Human natural regulatory T cell development, suppressive function, and postthymic maturation in a humanized mouse model.

Onoe T, Kalscheuer H, Danzl N, Chittenden M, Zhao G, Yang YG, Sykes M.

J Immunol. 2011 Oct 1;187(7):3895-903. doi: 10.4049/jimmunol.1100394. Epub 2011 Aug 29.

13.

Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin.

Danzl NM, Donlin LT, Alexandropoulos K.

J Exp Med. 2010 May 10;207(5):999-1013. doi: 10.1084/jem.20092384. Epub 2010 Apr 19.

14.

Conservation of CD1 protein expression patterns in the chicken.

Ly N, Danzl NM, Wang J, Zajonc DM, Dascher CC.

Dev Comp Immunol. 2010 Feb;34(2):123-32. doi: 10.1016/j.dci.2009.08.015. Epub 2009 Sep 11.

PMID:
19735672
15.
16.

Cycles of chromosome instability are associated with a fragile site and are increased by defects in DNA replication and checkpoint controls in yeast.

Admire A, Shanks L, Danzl N, Wang M, Weier U, Stevens W, Hunt E, Weinert T.

Genes Dev. 2006 Jan 15;20(2):159-73. Epub 2005 Dec 29.

17.

Deficiency in expression of the signaling protein Sin/Efs leads to T-lymphocyte activation and mucosal inflammation.

Donlin LT, Danzl NM, Wanjalla C, Alexandropoulos K.

Mol Cell Biol. 2005 Dec;25(24):11035-46.

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