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Items: 1 to 50 of 63


Immature murine hippocampal neurones do not develop long-term structural changes after a single isoflurane exposure.

Tong D, Godale CM, Kadakia FK, Gu Z, Danzer CSK, Alghamdi A, Zhao P, Loepke AW, Danzer SC.

Br J Anaesth. 2019 Dec;123(6):818-826. doi: 10.1016/j.bja.2019.08.019. Epub 2019 Sep 28.


Blocking TrkB's Effectors Reveal Benefits of the Road Not Taken.

Danzer SC.

Epilepsy Curr. 2019 Nov-Dec;19(6):405-407. doi: 10.1177/1535759719872503. Epub 2019 Sep 9.


Adult Neurogenesis in the Development of Epilepsy.

Danzer SC.

Epilepsy Curr. 2019 Sep;19(5):316-320. doi: 10.1177/1535759719868186. Epub 2019 Aug 13.


Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors?

LaSarge CL, Pun RYK, Gu Z, Santos VR, Danzer SC.

Exp Neurol. 2019 Nov;321:113029. doi: 10.1016/j.expneurol.2019.113029. Epub 2019 Aug 1.


MicroRNA inhibition upregulates hippocampal A-type potassium current and reduces seizure frequency in a mouse model of epilepsy.

Tiwari D, Brager DH, Rymer JK, Bunk AT, White AR, Elsayed NA, Krzeski JC, Snider A, Schroeder Carter LM, Danzer SC, Gross C.

Neurobiol Dis. 2019 Oct;130:104508. doi: 10.1016/j.nbd.2019.104508. Epub 2019 Jun 15.


A Hit, a Hit-A Very Palpable Hit: Mild TBI and the Development of Epilepsy.

Danzer SC.

Epilepsy Curr. 2019 Jul-Aug;19(4):261-263. doi: 10.1177/1535759719854758. Epub 2019 Jun 17.


Valproic Acid Leads New Neurons Down the Wrong Path.

Danzer SC.

Epilepsy Curr. 2019 Mar-Apr;19(2):132-133. doi: 10.1177/1535759719835366.


Double agent mTOR.

Danzer SC.

Epilepsy Curr. 2019 Jan;19(1):44-46. doi: 10.1177/1535759718822033. Epub 2019 Jan 30.


Impact of Traumatic Brain Injury on Neurogenesis.

Ngwenya LB, Danzer SC.

Front Neurosci. 2019 Jan 9;12:1014. doi: 10.3389/fnins.2018.01014. eCollection 2018.


Adult Neurogenesis in the Human Brain: Paradise Lost?

Danzer SC.

Epilepsy Curr. 2018 Sep-Oct;18(5):329-331. doi: 10.5698/1535-7597.18.5.329. No abstract available.


Self-reinforcing effects of mTOR hyperactive neurons on dendritic growth.

Arafa SR, LaSarge CL, Pun RYK, Khademi S, Danzer SC.

Exp Neurol. 2019 Jan;311:125-134. doi: 10.1016/j.expneurol.2018.09.019. Epub 2018 Sep 28.


Finding Your Inner Light: Using Bioluminescence to Control Seizures.

Danzer SC.

Epilepsy Curr. 2018 May-Jun;18(3):182-183. doi: 10.5698/1535-7597.18.3.182. No abstract available.


Functional disruption of stress modulatory circuits in a model of temporal lobe epilepsy.

Wulsin AC, Franco-Villanueva A, Romancheck C, Morano RL, Smith BL, Packard BA, Danzer SC, Herman JP.

PLoS One. 2018 May 24;13(5):e0197955. doi: 10.1371/journal.pone.0197955. eCollection 2018.


Signaling Pathways and Cellular Mechanisms Regulating Mossy Fiber Sprouting in the Development of Epilepsy.

Godale CM, Danzer SC.

Front Neurol. 2018 May 3;9:298. doi: 10.3389/fneur.2018.00298. eCollection 2018. Review.


Ablation of peri-insult generated granule cells after epilepsy onset halts disease progression.

Hosford BE, Rowley S, Liska JP, Danzer SC.

Sci Rep. 2017 Dec 21;7(1):18015. doi: 10.1038/s41598-017-18237-6.


Cannabinoid receptor 1/2 double-knockout mice develop epilepsy.

Rowley S, Sun X, Lima IV, Tavenier A, de Oliveira ACP, Dey SK, Danzer SC.

Epilepsia. 2017 Dec;58(12):e162-e166. doi: 10.1111/epi.13930. Epub 2017 Nov 3.


PTEN deletion increases hippocampal granule cell excitability in male and female mice.

Santos VR, Pun RYK, Arafa SR, LaSarge CL, Rowley S, Khademi S, Bouley T, Holland KD, Garcia-Cairasco N, Danzer SC.

Neurobiol Dis. 2017 Dec;108:339-351. doi: 10.1016/j.nbd.2017.08.014. Epub 2017 Sep 21.


RU486 Mitigates Hippocampal Pathology Following Status Epilepticus.

Wulsin AC, Herman JP, Danzer SC.

Front Neurol. 2016 Nov 28;7:214. eCollection 2016.


Ablation of Newly Generated Hippocampal Granule Cells Has Disease-Modifying Effects in Epilepsy.

Hosford BE, Liska JP, Danzer SC.

J Neurosci. 2016 Oct 26;36(43):11013-11023.


Disrupted hippocampal network physiology following PTEN deletion from newborn dentate granule cells.

LaSarge CL, Pun RY, Muntifering MB, Danzer SC.

Neurobiol Dis. 2016 Dec;96:105-114. doi: 10.1016/j.nbd.2016.09.004. Epub 2016 Sep 3.


MicroRNA-Mediated Downregulation of the Potassium Channel Kv4.2 Contributes to Seizure Onset.

Gross C, Yao X, Engel T, Tiwari D, Xing L, Rowley S, Danielson SW, Thomas KT, Jimenez-Mateos EM, Schroeder LM, Pun RYK, Danzer SC, Henshall DC, Bassell GJ.

Cell Rep. 2016 Sep 27;17(1):37-45. doi: 10.1016/j.celrep.2016.08.074.


Long-term Fate Mapping to Assess the Impact of Postnatal Isoflurane Exposure on Hippocampal Progenitor Cell Productivity.

Jiang Y, Tong D, Hofacer RD, Loepke AW, Lian Q, Danzer SC.

Anesthesiology. 2016 Dec;125(6):1159-1170.


Intra-amniotic LPS causes acute neuroinflammation in preterm rhesus macaques.

Schmidt AF, Kannan PS, Chougnet CA, Danzer SC, Miller LA, Jobe AH, Kallapur SG.

J Neuroinflammation. 2016 Sep 6;13(1):238. doi: 10.1186/s12974-016-0706-4.


Neurogenesis in Epilepsy: Better to Burn Out or Fade Away?

Danzer SC.

Epilepsy Curr. 2016 Jul-Aug;16(4):268-9. doi: 10.5698/1535-7511-16.4.268. No abstract available.


Hypothalamic-pituitary-adrenocortical axis dysfunction in epilepsy.

Wulsin AC, Solomon MB, Privitera MD, Danzer SC, Herman JP.

Physiol Behav. 2016 Nov 1;166:22-31. doi: 10.1016/j.physbeh.2016.05.015. Epub 2016 May 16. Review.


Impact of rapamycin on status epilepticus induced hippocampal pathology and weight gain.

Hester MS, Hosford BE, Santos VR, Singh SP, Rolle IJ, LaSarge CL, Liska JP, Garcia-Cairasco N, Danzer SC.

Exp Neurol. 2016 Jun;280:1-12. doi: 10.1016/j.expneurol.2016.03.015. Epub 2016 Mar 17.


Clonal Analysis of Newborn Hippocampal Dentate Granule Cell Proliferation and Development in Temporal Lobe Epilepsy.

Singh SP, LaSarge CL, An A, McAuliffe JJ, Danzer SC.

eNeuro. 2016 Jan 9;2(6). pii: ENEURO.0087-15.2015. doi: 10.1523/ENEURO.0087-15.2015. eCollection 2015 Nov-Dec.


Adult Neurogenesis: Opening the Gates of Troy From the Inside.

Danzer SC.

Epilepsy Curr. 2015 Sep-Oct;15(5):263-4. doi: 10.5698/1535-7511-15.5.263. No abstract available.


Olfactory Bulbectomy Leads to the Development of Epilepsy in Mice.

Jiang Y, Pun RY, Peariso K, Holland KD, Lian Q, Danzer SC.

PLoS One. 2015 Sep 14;10(9):e0138178. doi: 10.1371/journal.pone.0138178. eCollection 2015.


PTEN deletion from adult-generated dentate granule cells disrupts granule cell mossy fiber axon structure.

LaSarge CL, Santos VR, Danzer SC.

Neurobiol Dis. 2015 Mar;75:142-50. doi: 10.1016/j.nbd.2014.12.029. Epub 2015 Jan 17.


Mechanisms regulating neuronal excitability and seizure development following mTOR pathway hyperactivation.

Lasarge CL, Danzer SC.

Front Mol Neurosci. 2014 Mar 14;7:18. doi: 10.3389/fnmol.2014.00018. eCollection 2014. Review.


Hippocampal granule cell pathology in epilepsy - a possible structural basis for comorbidities of epilepsy?

Hester MS, Danzer SC.

Epilepsy Behav. 2014 Sep;38:105-16. doi: 10.1016/j.yebeh.2013.12.022. Epub 2014 Jan 24. Review.


Brain regional vulnerability to anaesthesia-induced neuroapoptosis shifts with age at exposure and extends into adulthood for some regions.

Deng M, Hofacer RD, Jiang C, Joseph B, Hughes EA, Jia B, Danzer SC, Loepke AW.

Br J Anaesth. 2014 Sep;113(3):443-51. doi: 10.1093/bja/aet469. Epub 2014 Jan 14.


Morphological changes among hippocampal dentate granule cells exposed to early kindling-epileptogenesis.

Singh SP, He X, McNamara JO, Danzer SC.

Hippocampus. 2013 Dec;23(12):1309-20. doi: 10.1002/hipo.22169. Epub 2013 Aug 26.


Accumulation of abnormal adult-generated hippocampal granule cells predicts seizure frequency and severity.

Hester MS, Danzer SC.

J Neurosci. 2013 May 22;33(21):8926-36. doi: 10.1523/JNEUROSCI.5161-12.2013.


Cell age-specific vulnerability of neurons to anesthetic toxicity.

Hofacer RD, Deng M, Ward CG, Joseph B, Hughes EA, Jiang C, Danzer SC, Loepke AW.

Ann Neurol. 2013 Jun;73(6):695-704. doi: 10.1002/ana.23892. Epub 2013 Jun 5.


Characterization and quantification of isoflurane-induced developmental apoptotic cell death in mouse cerebral cortex.

Istaphanous GK, Ward CG, Nan X, Hughes EA, McCann JC, McAuliffe JJ, Danzer SC, Loepke AW.

Anesth Analg. 2013 Apr;116(4):845-54. doi: 10.1213/ANE.0b013e318281e988. Epub 2013 Mar 4.


Impact of corticosterone treatment on spontaneous seizure frequency and epileptiform activity in mice with chronic epilepsy.

Castro OW, Santos VR, Pun RY, McKlveen JM, Batie M, Holland KD, Gardner M, Garcia-Cairasco N, Herman JP, Danzer SC.

PLoS One. 2012;7(9):e46044. doi: 10.1371/journal.pone.0046044. Epub 2012 Sep 28.


Excessive activation of mTOR in postnatally generated granule cells is sufficient to cause epilepsy.

Pun RY, Rolle IJ, Lasarge CL, Hosford BE, Rosen JM, Uhl JD, Schmeltzer SN, Faulkner C, Bronson SL, Murphy BL, Richards DA, Holland KD, Danzer SC.

Neuron. 2012 Sep 20;75(6):1022-34. doi: 10.1016/j.neuron.2012.08.002.


Abnormalities of granule cell dendritic structure are a prominent feature of the intrahippocampal kainic acid model of epilepsy despite reduced postinjury neurogenesis.

Murphy BL, Hofacer RD, Faulkner CN, Loepke AW, Danzer SC.

Epilepsia. 2012 May;53(5):908-21. doi: 10.1111/j.1528-1167.2012.03463.x.


Contributions of mature granule cells to structural plasticity in temporal lobe epilepsy.

Santos VR, de Castro OW, Pun RY, Hester MS, Murphy BL, Loepke AW, Garcia-Cairasco N, Danzer SC.

Neuroscience. 2011 Dec 1;197:348-57. doi: 10.1016/j.neuroscience.2011.09.034. Epub 2011 Sep 19.


Depression, stress, epilepsy and adult neurogenesis.

Danzer SC.

Exp Neurol. 2012 Jan;233(1):22-32. doi: 10.1016/j.expneurol.2011.05.023. Epub 2011 Jun 12. Review.


Somatic translocation: a novel mechanism of granule cell dendritic dysmorphogenesis and dispersion.

Murphy BL, Danzer SC.

J Neurosci. 2011 Feb 23;31(8):2959-64. doi: 10.1523/JNEUROSCI.3381-10.2011.


Comparison of the neuroapoptotic properties of equipotent anesthetic concentrations of desflurane, isoflurane, or sevoflurane in neonatal mice.

Istaphanous GK, Howard J, Nan X, Hughes EA, McCann JC, McAuliffe JJ, Danzer SC, Loepke AW.

Anesthesiology. 2011 Mar;114(3):578-87. doi: 10.1097/ALN.0b013e3182084a70.


Heterogeneous integration of adult-generated granule cells into the epileptic brain.

Murphy BL, Pun RY, Yin H, Faulkner CR, Loepke AW, Danzer SC.

J Neurosci. 2011 Jan 5;31(1):105-17. doi: 10.1523/JNEUROSCI.2728-10.2011.


A novel Akt3 mutation associated with enhanced kinase activity and seizure susceptibility in mice.

Tokuda S, Mahaffey CL, Monks B, Faulkner CR, Birnbaum MJ, Danzer SC, Frankel WN.

Hum Mol Genet. 2011 Mar 1;20(5):988-99. doi: 10.1093/hmg/ddq544. Epub 2010 Dec 15.


Rapid formation of extended processes and engagement of Theiler's virus-infected neurons by CNS-infiltrating CD8 T cells.

McDole JR, Danzer SC, Pun RY, Chen Y, Johnson HL, Pirko I, Johnson AJ.

Am J Pathol. 2010 Oct;177(4):1823-33. doi: 10.2353/ajpath.2010.100231. Epub 2010 Sep 2.


Altered patterning of dentate granule cell mossy fiber inputs onto CA3 pyramidal cells in limbic epilepsy.

McAuliffe JJ, Bronson SL, Hester MS, Murphy BL, Dahlquist-Topalá R, Richards DA, Danzer SC.

Hippocampus. 2011 Jan;21(1):93-107. doi: 10.1002/hipo.20726.


Structural plasticity of dentate granule cell mossy fibers during the development of limbic epilepsy.

Danzer SC, He X, Loepke AW, McNamara JO.

Hippocampus. 2010 Jan;20(1):113-24. doi: 10.1002/hipo.20589.

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