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Items: 1 to 50 of 140

1.

Automated profiling of growth cone heterogeneity defines relations between morphology and motility.

Bagonis MM, Fusco L, Pertz O, Danuser G.

J Cell Biol. 2018 Dec 6. pii: jcb.201711023. doi: 10.1083/jcb.201711023. [Epub ahead of print]

PMID:
30523041
2.

Profiling cellular morphodynamics by spatiotemporal spectrum decomposition.

Ma X, Dagliyan O, Hahn KM, Danuser G.

PLoS Comput Biol. 2018 Aug 2;14(8):e1006321. doi: 10.1371/journal.pcbi.1006321. eCollection 2018 Aug.

3.

Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3.

Lee JJ, van de Ven RAH, Zaganjor E, Ng MR, Barakat A, Demmers JJPG, Finley LWS, Gonzalez Herrera KN, Hung YP, Harris IS, Jeong SM, Danuser G, McAllister SS, Haigis MC.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7057-7062. doi: 10.1073/pnas.1800440115. Epub 2018 Jun 18.

4.

A noncanonical role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells.

Srinivasan S, Burckhardt CJ, Bhave M, Chen Z, Chen PH, Wang X, Danuser G, Schmid SL.

PLoS Biol. 2018 Apr 18;16(4):e2005377. doi: 10.1371/journal.pbio.2005377. eCollection 2018 Apr.

5.

Regulation of Clathrin-Mediated Endocytosis.

Mettlen M, Chen PH, Srinivasan S, Danuser G, Schmid SL.

Annu Rev Biochem. 2018 Jun 20;87:871-896. doi: 10.1146/annurev-biochem-062917-012644. Epub 2018 Apr 16.

PMID:
29661000
6.

Discovery of functional interactions among actin regulators by analysis of image fluctuations in an unperturbed motile cell system.

Isogai T, Danuser G.

Philos Trans R Soc Lond B Biol Sci. 2018 May 26;373(1747). pii: 20170110. doi: 10.1098/rstb.2017.0110. Review.

PMID:
29632262
7.

Piecewise-Stationary Motion Modeling and Iterative Smoothing to Track Heterogeneous Particle Motions in Dense Environments.

Roudot P, Liya Ding, Jaqaman K, Kervrann C, Danuser G.

IEEE Trans Image Process. 2017 Nov;26(11):5395-5410. doi: 10.1109/TIP.2017.2707803.

8.

A method for measuring the distribution of the shortest telomeres in cells and tissues.

Lai TP, Zhang N, Noh J, Mender I, Tedone E, Huang E, Wright WE, Danuser G, Shay JW.

Nat Commun. 2017 Nov 7;8(1):1356. doi: 10.1038/s41467-017-01291-z.

9.

Differential KrasV12 protein levels control a switch regulating lung cancer cell morphology and motility.

Schäfer C, Mohan A, Burford W, Driscoll MK, Ludlow AT, Wright WE, Shay JW, Danuser G.

Converg Sci Phys Oncol. 2016 Sep;2(3):035004. doi: 10.1088/2057-1739/2/3/035004. Epub 2016 Sep 20.

10.

Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane.

Werbin JL, Avendaño MS, Becker V, Jungmann R, Yin P, Danuser G, Sorger PK.

Sci Rep. 2017 Sep 22;7(1):12150. doi: 10.1038/s41598-017-12257-y.

11.

Cell forces meet cell metabolism.

Isogai T, Park JS, Danuser G.

Nat Cell Biol. 2017 May 31;19(6):591-593. doi: 10.1038/ncb3542.

PMID:
28561051
12.

Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration.

Zaritsky A, Tseng YY, Rabadán MA, Krishna S, Overholtzer M, Danuser G, Hall A.

J Cell Biol. 2017 Jun 5;216(6):1543-1556. doi: 10.1083/jcb.201609095. Epub 2017 May 16.

13.

Vimentin fibers orient traction stress.

Costigliola N, Ding L, Burckhardt CJ, Han SJ, Gutierrez E, Mota A, Groisman A, Mitchison TJ, Danuser G.

Proc Natl Acad Sci U S A. 2017 May 16;114(20):5195-5200. doi: 10.1073/pnas.1614610114. Epub 2017 May 2.

14.

Decoupling global biases and local interactions between cell biological variables.

Zaritsky A, Obolski U, Gan Z, Reis CR, Kadlecova Z, Du Y, Schmid SL, Danuser G.

Elife. 2017 Mar 13;6. pii: e22323. doi: 10.7554/eLife.22323.

15.

Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration.

Gan Z, Ding L, Burckhardt CJ, Lowery J, Zaritsky A, Sitterley K, Mota A, Costigliola N, Starker CG, Voytas DF, Tytell J, Goldman RD, Danuser G.

Cell Syst. 2016 Nov 23;3(5):500-501. doi: 10.1016/j.cels.2016.11.011. No abstract available.

16.

Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy.

Aguet F, Upadhyayula S, Gaudin R, Chou YY, Cocucci E, He K, Chen BC, Mosaliganti K, Pasham M, Skillern W, Legant WR, Liu TL, Findlay G, Marino E, Danuser G, Megason S, Betzig E, Kirchhausen T.

Mol Biol Cell. 2016 Nov 7;27(22):3418-3435. Epub 2016 Aug 17.

17.

Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration.

Gan Z, Ding L, Burckhardt CJ, Lowery J, Zaritsky A, Sitterley K, Mota A, Costigliola N, Starker CG, Voytas DF, Tytell J, Goldman RD, Danuser G.

Cell Syst. 2016 Sep 28;3(3):252-263.e8. doi: 10.1016/j.cels.2016.08.007. Epub 2016 Sep 22. Erratum in: Cell Syst. 2016 Nov 23;3(5):500-501.

18.

FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions.

Hodgson L, Spiering D, Sabouri-Ghomi M, Dagliyan O, DerMardirossian C, Danuser G, Hahn KM.

Nat Chem Biol. 2016 Oct;12(10):802-809. doi: 10.1038/nchembio.2145. Epub 2016 Aug 8.

19.

LOVTRAP: an optogenetic system for photoinduced protein dissociation.

Wang H, Vilela M, Winkler A, Tarnawski M, Schlichting I, Yumerefendi H, Kuhlman B, Liu R, Danuser G, Hahn KM.

Nat Methods. 2016 Sep;13(9):755-8. doi: 10.1038/nmeth.3926. Epub 2016 Jul 18.

20.

Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments.

Welf ES, Driscoll MK, Dean KM, Schäfer C, Chu J, Davidson MW, Lin MZ, Danuser G, Fiolka R.

Dev Cell. 2016 Feb 22;36(4):462-75. doi: 10.1016/j.devcel.2016.01.022.

21.

Seeds of Locally Aligned Motion and Stress Coordinate a Collective Cell Migration.

Zaritsky A, Welf ES, Tseng YY, Angeles Rabadán M, Serra-Picamal X, Trepat X, Danuser G.

Biophys J. 2015 Dec 15;109(12):2492-2500. doi: 10.1016/j.bpj.2015.11.001.

22.

Quantifying Modes of 3D Cell Migration.

Driscoll MK, Danuser G.

Trends Cell Biol. 2015 Dec;25(12):749-759. doi: 10.1016/j.tcb.2015.09.010. Epub 2015 Oct 23. Review.

23.

Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization.

Lomakin AJ, Lee KC, Han SJ, Bui DA, Davidson M, Mogilner A, Danuser G.

Nat Cell Biol. 2015 Nov;17(11):1435-45. doi: 10.1038/ncb3246. Epub 2015 Sep 28.

24.

Functional hierarchy of redundant actin assembly factors revealed by fine-grained registration of intrinsic image fluctuations.

Lee K, Elliott HL, Oak Y, Zee CT, Groisman A, Tytell JD, Danuser G.

Cell Syst. 2015 Jul 29;1(1):37-50.

25.

Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds.

Kwon M, Bagonis M, Danuser G, Pellman D.

Dev Cell. 2015 Aug 10;34(3):323-37. doi: 10.1016/j.devcel.2015.06.013. Epub 2015 Jul 30.

26.

Deconvolution-free Subcellular Imaging with Axially Swept Light Sheet Microscopy.

Dean KM, Roudot P, Welf ES, Danuser G, Fiolka R.

Biophys J. 2015 Jun 16;108(12):2807-15. doi: 10.1016/j.bpj.2015.05.013.

27.

Traction microscopy to identify force modulation in subresolution adhesions.

Han SJ, Oak Y, Groisman A, Danuser G.

Nat Methods. 2015 Jul;12(7):653-6. doi: 10.1038/nmeth.3430. Epub 2015 Jun 1.

28.

ERK reinforces actin polymerization to power persistent edge protrusion during motility.

Mendoza MC, Vilela M, Juarez JE, Blenis J, Danuser G.

Sci Signal. 2015 May 19;8(377):ra47. doi: 10.1126/scisignal.aaa8859.

29.

In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy.

Chittajallu DR, Florian S, Kohler RH, Iwamoto Y, Orth JD, Weissleder R, Danuser G, Mitchison TJ.

Nat Methods. 2015 Jun;12(6):577-85. doi: 10.1038/nmeth.3363. Epub 2015 Apr 13.

30.

Microtubule-dependent transport and dynamics of vimentin intermediate filaments.

Hookway C, Ding L, Davidson MW, Rappoport JZ, Danuser G, Gelfand VI.

Mol Biol Cell. 2015 May 1;26(9):1675-86. doi: 10.1091/mbc.E14-09-1398. Epub 2015 Feb 25.

31.

Correction: Mapping the dynamics of force transduction at cell-cell junctions of epithelial clusters.

Ng MR, Besser A, Brugge JS, Danuser G.

Elife. 2015 Feb 2;4:e06656. doi: 10.7554/eLife.06656. No abstract available.

32.

Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature.

Elliott H, Fischer RS, Myers KA, Desai RA, Gao L, Chen CS, Adelstein RS, Waterman CM, Danuser G.

Nat Cell Biol. 2015 Feb;17(2):137-47. doi: 10.1038/ncb3092. Epub 2015 Jan 26.

33.

Mapping the dynamics of force transduction at cell-cell junctions of epithelial clusters.

Ng MR, Besser A, Brugge JS, Danuser G.

Elife. 2014 Dec 5;3:e03282. doi: 10.7554/eLife.03282. Erratum in: Elife. 2015;4:e06656.

34.

Using fluctuation analysis to establish causal relations between cellular events without experimental perturbation.

Welf ES, Danuser G.

Biophys J. 2014 Dec 2;107(11):2492-8. doi: 10.1016/j.bpj.2014.10.032. Epub 2014 Dec 2. Review.

35.

A growth factor-induced, spatially organizing cytoskeletal module enables rapid and persistent fibroblast migration.

Martin K, Vilela M, Jeon NL, Danuser G, Pertz O.

Dev Cell. 2014 Sep 29;30(6):701-16. doi: 10.1016/j.devcel.2014.07.022.

36.

Imaging and modeling the dynamics of clathrin-mediated endocytosis.

Mettlen M, Danuser G.

Cold Spring Harb Perspect Biol. 2014 Aug 28;6(12):a017038. doi: 10.1101/cshperspect.a017038. Review.

37.

Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides.

Yi JJ, Wang H, Vilela M, Danuser G, Hahn KM.

ACS Synth Biol. 2014 Nov 21;3(11):788-95. doi: 10.1021/sb5001356. Epub 2014 Jun 13.

38.

Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration.

Cai D, Chen SC, Prasad M, He L, Wang X, Choesmel-Cadamuro V, Sawyer JK, Danuser G, Montell DJ.

Cell. 2014 May 22;157(5):1146-59. doi: 10.1016/j.cell.2014.03.045.

39.

Reply to "Acquisition frame rate affects microtubule plus-end tracking analysis".

Danuser G.

Nat Methods. 2014 Mar;11(3):220. doi: 10.1038/nmeth.2860. No abstract available.

PMID:
24577269
40.

Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth.

Lowery LA, Stout A, Faris AE, Ding L, Baird MA, Davidson MW, Danuser G, Van Vactor D.

Neural Dev. 2013 Dec 1;8:22. doi: 10.1186/1749-8104-8-22.

41.

Tumor suppressor NF2/Merlin is a microtubule stabilizer.

Smole Z, Thoma CR, Applegate KT, Duda M, Gutbrodt KL, Danuser G, Krek W.

Cancer Res. 2014 Jan 1;74(1):353-62. doi: 10.1158/0008-5472.CAN-13-1334. Epub 2013 Nov 26.

42.

A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cells.

Zawistowski JS, Sabouri-Ghomi M, Danuser G, Hahn KM, Hodgson L.

PLoS One. 2013 Nov 5;8(11):e79877. doi: 10.1371/journal.pone.0079877. eCollection 2013.

43.

S. cerevisiae chromosomes biorient via gradual resolution of syntely between S phase and anaphase.

Marco E, Dorn JF, Hsu PH, Jaqaman K, Sorger PK, Danuser G.

Cell. 2013 Aug 29;154(5):1127-1139. doi: 10.1016/j.cell.2013.08.008.

44.

Mathematical modeling of eukaryotic cell migration: insights beyond experiments.

Danuser G, Allard J, Mogilner A.

Annu Rev Cell Dev Biol. 2013;29:501-28. doi: 10.1146/annurev-cellbio-101512-122308. Epub 2013 Jul 24. Review.

45.

Advances in analysis of low signal-to-noise images link dynamin and AP2 to the functions of an endocytic checkpoint.

Aguet F, Antonescu CN, Mettlen M, Schmid SL, Danuser G.

Dev Cell. 2013 Aug 12;26(3):279-91. doi: 10.1016/j.devcel.2013.06.019. Epub 2013 Jul 25.

46.

Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth.

Thievessen I, Thompson PM, Berlemont S, Plevock KM, Plotnikov SV, Zemljic-Harpf A, Ross RS, Davidson MW, Danuser G, Campbell SL, Waterman CM.

J Cell Biol. 2013 Jul 8;202(1):163-77. doi: 10.1083/jcb.201303129.

47.

Multiparametric analysis of CLASP-interacting protein functions during interphase microtubule dynamics.

Long JB, Bagonis M, Lowery LA, Lee H, Danuser G, Van Vactor D.

Mol Cell Biol. 2013 Apr;33(8):1528-45. doi: 10.1128/MCB.01442-12. Epub 2013 Feb 4.

48.

Fluctuation analysis of activity biosensor images for the study of information flow in signaling pathways.

Vilela M, Halidi N, Besson S, Elliott H, Hahn K, Tytell J, Danuser G.

Methods Enzymol. 2013;519:253-76. doi: 10.1016/B978-0-12-405539-1.00009-9.

49.

Gaudenz Danuser: the symphony of the cell. Interview by Caitlin Sedwick.

Danuser G.

J Cell Biol. 2012 Nov 12;199(4):568-9. doi: 10.1083/jcb.1994pi. No abstract available.

50.

Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility.

Ng MR, Besser A, Danuser G, Brugge JS.

J Cell Biol. 2012 Oct 29;199(3):545-63. doi: 10.1083/jcb.201207148. Epub 2012 Oct 22.

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