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Items: 1 to 50 of 405

1.

Cancer exosomes induce tumor innervation.

Madeo M, Colbert PL, Vermeer DW, Lucido CT, Cain JT, Vichaya EG, Grossberg AJ, Muirhead D, Rickel AP, Hong Z, Zhao J, Weimer JM, Spanos WC, Lee JH, Dantzer R, Vermeer PD.

Nat Commun. 2018 Oct 16;9(1):4284. doi: 10.1038/s41467-018-06640-0.

2.

Protocol for the insight study: a randomised controlled trial of single-dose tocilizumab in patients with depression and low-grade inflammation.

Khandaker GM, Oltean BP, Kaser M, Dibben CRM, Ramana R, Jadon DR, Dantzer R, Coles AJ, Lewis G, Jones PB.

BMJ Open. 2018 Sep 21;8(9):e025333. doi: 10.1136/bmjopen-2018-025333.

3.

Resilience and immunity.

Dantzer R, Cohen S, Russo SJ, Dinan TG.

Brain Behav Immun. 2018 Aug 10. pii: S0889-1591(18)30440-9. doi: 10.1016/j.bbi.2018.08.010. [Epub ahead of print] Review.

4.

Resolution of inflammation-induced depression requires T lymphocytes and endogenous brain interleukin-10 signaling.

Laumet G, Edralin JD, Chiang AC, Dantzer R, Heijnen CJ, Kavelaars A.

Neuropsychopharmacology. 2018 Dec;43(13):2597-2605. doi: 10.1038/s41386-018-0154-1. Epub 2018 Jul 16.

PMID:
30054585
5.

Disruption of microglia histone acetylation and protein pathways in mice exhibiting inflammation-associated depression-like symptoms.

Rodriguez-Zas SL, Wu C, Southey BR, O'Connor JC, Nixon SE, Garcia R, Zavala C, Lawson M, McCusker RH, Romanova EV, Sweedler JV, Kelley KW, Dantzer R.

Psychoneuroendocrinology. 2018 Nov;97:47-58. doi: 10.1016/j.psyneuen.2018.06.024. Epub 2018 Jun 30.

PMID:
30005281
6.

Leucine competes with kynurenine for blood-to-brain transport and prevents lipopolysaccharide-induced depression-like behavior in mice.

Walker AK, Wing EE, Banks WA, Dantzer R.

Mol Psychiatry. 2018 Jul 9. doi: 10.1038/s41380-018-0076-7. [Epub ahead of print]

PMID:
29988087
7.

Can cancer-related cognitive impairment be considered in isolation from other cancer-related symptoms?

Lacourt TE, De La Garza R 2nd, Dantzer R.

Psychooncology. 2018 Oct;27(10):2511-2512. doi: 10.1002/pon.4826. Epub 2018 Jul 18. No abstract available.

PMID:
29956401
8.

Role of Kynurenine pathway and its metabolites in mood disorders: A systematic review and meta-analysis of clinical studies.

Arnone D, Saraykar S, Salem H, Teixeira AL, Dantzer R, Selvaraj S.

Neurosci Biobehav Rev. 2018 Sep;92:477-485. doi: 10.1016/j.neubiorev.2018.05.031. Epub 2018 Jun 22. Review.

PMID:
29940237
9.

An effort expenditure perspective on cancer-related fatigue.

Lacourt TE, Vichaya EG, Escalante C, Manzullo EF, Gunn B, Hess KR, Heijnen CJ, Dantzer R.

Psychoneuroendocrinology. 2018 Oct;96:109-117. doi: 10.1016/j.psyneuen.2018.06.009. Epub 2018 Jun 9.

PMID:
29929087
10.

Inflammation-induced motivational changes: Perspective gained by evaluating positive and negative valence systems.

Vichaya EG, Dantzer R.

Curr Opin Behav Sci. 2018 Aug;22:90-95. doi: 10.1016/j.cobeha.2018.01.008. Epub 2018 Feb 10.

PMID:
29888301
11.

Motivational changes that develop in a mouse model of inflammation-induced depression are independent of indoleamine 2,3 dioxygenase.

Vichaya EG, Laumet G, Christian DL, Grossberg AJ, Estrada DJ, Heijnen CJ, Kavelaars A, Dantzer R.

Neuropsychopharmacology. 2018 Apr 27. doi: 10.1038/s41386-018-0075-z. [Epub ahead of print]

PMID:
29760410
12.

The High Costs of Low-Grade Inflammation: Persistent Fatigue as a Consequence of Reduced Cellular-Energy Availability and Non-adaptive Energy Expenditure.

Lacourt TE, Vichaya EG, Chiu GS, Dantzer R, Heijnen CJ.

Front Behav Neurosci. 2018 Apr 26;12:78. doi: 10.3389/fnbeh.2018.00078. eCollection 2018. Review.

13.

The effect of insulin-induced hypoglycemia on inflammatory markers: A systematic review.

Drummond JB, Barbosa IG, Dantzer R, Teixeira AL.

Brain Behav Immun. 2018 Oct;73:41-50. doi: 10.1016/j.bbi.2018.05.003. Epub 2018 May 4. Review.

PMID:
29733946
14.

Functional TSPO polymorphism predicts variance in the diurnal cortisol rhythm in bipolar disorder.

Prossin AR, Chandler M, Ryan KA, Saunders EF, Kamali M, Papadopoulos V, Zöllner S, Dantzer R, McInnis MG.

Psychoneuroendocrinology. 2018 Mar;89:194-202. doi: 10.1016/j.psyneuen.2018.01.013. Epub 2018 Jan 31.

PMID:
29414032
15.

Neuroimmune Interactions: From the Brain to the Immune System and Vice Versa.

Dantzer R.

Physiol Rev. 2018 Jan 1;98(1):477-504. doi: 10.1152/physrev.00039.2016. Review.

PMID:
29351513
16.

Tumor-Associated Fatigue in Cancer Patients Develops Independently of IL1 Signaling.

Grossberg AJ, Vichaya EG, Christian DL, Molkentine JM, Vermeer DW, Gross PS, Vermeer PD, Lee JH, Dantzer R.

Cancer Res. 2018 Feb 1;78(3):695-705. doi: 10.1158/0008-5472.CAN-17-2168. Epub 2017 Dec 7.

PMID:
29217760
17.

Immune-based strategies for mood disorders: facts and challenges.

Colpo GD, Leboyer M, Dantzer R, Trivedi MH, Teixeira AL.

Expert Rev Neurother. 2018 Feb;18(2):139-152. doi: 10.1080/14737175.2018.1407242. Epub 2017 Nov 27.

PMID:
29179585
18.

Mechanisms of poststroke fatigue.

De Doncker W, Dantzer R, Ormstad H, Kuppuswamy A.

J Neurol Neurosurg Psychiatry. 2018 Mar;89(3):287-293. doi: 10.1136/jnnp-2017-316007. Epub 2017 Sep 22. Review.

PMID:
28939684
19.

Kynurenic acid is reduced in females and oral contraceptive users: Implications for depression.

Meier TB, Drevets WC, Teague TK, Wurfel BE, Mueller SC, Bodurka J, Dantzer R, Savitz J.

Brain Behav Immun. 2018 Jan;67:59-64. doi: 10.1016/j.bbi.2017.08.024. Epub 2017 Sep 1.

PMID:
28867283
20.

Sleep disturbance and kynurenine metabolism in depression.

Cho HJ, Savitz J, Dantzer R, Teague TK, Drevets WC, Irwin MR.

J Psychosom Res. 2017 Aug;99:1-7. doi: 10.1016/j.jpsychores.2017.05.016. Epub 2017 May 22.

21.

Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain.

Laumet G, Zhou W, Dantzer R, Edralin JD, Huo X, Budac DP, O'Connor JC, Lee AW, Heijnen CJ, Kavelaars A.

Brain Behav Immun. 2017 Nov;66:94-102. doi: 10.1016/j.bbi.2017.07.008. Epub 2017 Jul 11.

22.

Serum kynurenic acid is reduced in affective psychosis.

Wurfel BE, Drevets WC, Bliss SA, McMillin JR, Suzuki H, Ford BN, Morris HM, Teague TK, Dantzer R, Savitz JB.

Transl Psychiatry. 2017 May 2;7(5):e1115. doi: 10.1038/tp.2017.88.

23.

Immunopsychiatry: important facts.

Khandaker GM, Dantzer R, Jones PB.

Psychol Med. 2017 Oct;47(13):2229-2237. doi: 10.1017/S0033291717000745. Epub 2017 Apr 18. Review.

24.

Neuroimmune mechanisms of behavioral alterations in a syngeneic murine model of human papilloma virus-related head and neck cancer.

Vichaya EG, Vermeer DW, Christian DL, Molkentine JM, Mason KA, Lee JH, Dantzer R.

Psychoneuroendocrinology. 2017 May;79:59-66. doi: 10.1016/j.psyneuen.2017.02.006. Epub 2017 Feb 11.

25.

Pifithrin-μ Prevents Cisplatin-Induced Chemobrain by Preserving Neuronal Mitochondrial Function.

Chiu GS, Maj MA, Rizvi S, Dantzer R, Vichaya EG, Laumet G, Kavelaars A, Heijnen CJ.

Cancer Res. 2017 Feb 1;77(3):742-752. doi: 10.1158/0008-5472.CAN-16-1817. Epub 2016 Nov 22.

26.

Antidepressant activity of anti-cytokine treatment: a systematic review and meta-analysis of clinical trials of chronic inflammatory conditions.

Kappelmann N, Lewis G, Dantzer R, Jones PB, Khandaker GM.

Mol Psychiatry. 2018 Feb;23(2):335-343. doi: 10.1038/mp.2016.167. Epub 2016 Oct 18.

27.

Lipopolysaccharide Alters Motivated Behavior in a Monetary Reward Task: a Randomized Trial.

Lasselin J, Treadway MT, Lacourt TE, Soop A, Olsson MJ, Karshikoff B, Paues-Göranson S, Axelsson J, Dantzer R, Lekander M.

Neuropsychopharmacology. 2017 Mar;42(4):801-810. doi: 10.1038/npp.2016.191. Epub 2016 Sep 13.

28.

Differential Transcriptome Networks between IDO1-Knockout and Wild-Type Mice in Brain Microglia and Macrophages.

Gonzalez-Pena D, Nixon SE, Southey BR, Lawson MA, McCusker RH, Hernandez AG, Dantzer R, Kelley KW, Rodriguez-Zas SL.

PLoS One. 2016 Jun 17;11(6):e0157727. doi: 10.1371/journal.pone.0157727. eCollection 2016.

29.

Role of the Kynurenine Metabolism Pathway in Inflammation-Induced Depression: Preclinical Approaches.

Dantzer R.

Curr Top Behav Neurosci. 2017;31:117-138. doi: 10.1007/7854_2016_6. Review.

PMID:
27225497
30.

Kynurenine pathway metabolites are associated with hippocampal activity during autobiographical memory recall in patients with depression.

Young KD, Drevets WC, Dantzer R, Teague TK, Bodurka J, Savitz J.

Brain Behav Immun. 2016 Aug;56:335-42. doi: 10.1016/j.bbi.2016.04.007. Epub 2016 Apr 29.

31.

Inflammation Models of Depression in Rodents: Relevance to Psychotropic Drug Discovery.

Remus JL, Dantzer R.

Int J Neuropsychopharmacol. 2016 Sep 21;19(9). pii: pyw028. doi: 10.1093/ijnp/pyw028. Print 2016 Sep. Review.

32.

Microglia Transcriptome Changes in a Model of Depressive Behavior after Immune Challenge.

Gonzalez-Pena D, Nixon SE, O'Connor JC, Southey BR, Lawson MA, McCusker RH, Borras T, Machuca D, Hernandez AG, Dantzer R, Kelley KW, Rodriguez-Zas SL.

PLoS One. 2016 Mar 9;11(3):e0150858. doi: 10.1371/journal.pone.0150858. eCollection 2016.

33.

Exercise, inflammation, and fatigue in cancer survivors.

LaVoy EC, Fagundes CP, Dantzer R.

Exerc Immunol Rev. 2016;22:82-93. Review.

34.

The cortisol awakening response at its best.

Dantzer R, Kalin NH.

Psychoneuroendocrinology. 2016 Jan;63:412-3. doi: 10.1016/j.psyneuen.2015.11.002. Epub 2015 Nov 18. No abstract available.

PMID:
26604094
35.

Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder.

Meier TB, Drevets WC, Wurfel BE, Ford BN, Morris HM, Victor TA, Bodurka J, Teague TK, Dantzer R, Savitz J.

Brain Behav Immun. 2016 Mar;53:39-48. doi: 10.1016/j.bbi.2015.11.003. Epub 2015 Nov 4.

36.

Sickness behavior induced by cisplatin chemotherapy and radiotherapy in a murine head and neck cancer model is associated with altered mitochondrial gene expression.

Vichaya EG, Molkentine JM, Vermeer DW, Walker AK, Feng R, Holder G, Luu K, Mason RM, Saligan L, Heijnen CJ, Kavelaars A, Mason KA, Lee JH, Dantzer R.

Behav Brain Res. 2016 Jan 15;297:241-50. doi: 10.1016/j.bbr.2015.10.024. Epub 2015 Oct 22.

37.

Activation of the kynurenine pathway is associated with striatal volume in major depressive disorder.

Savitz J, Dantzer R, Meier TB, Wurfel BE, Victor TA, McIntosh SA, Ford BN, Morris HM, Bodurka J, Teague TK, Drevets WC.

Psychoneuroendocrinology. 2015 Dec;62:54-8. doi: 10.1016/j.psyneuen.2015.07.609. Epub 2015 Jul 26.

38.

Is there a role for immune-to-brain communication in schizophrenia?

Khandaker GM, Dantzer R.

Psychopharmacology (Berl). 2016 May;233(9):1559-73. doi: 10.1007/s00213-015-3975-1. Epub 2015 Jun 4. Review.

39.

Mechanisms of chemotherapy-induced behavioral toxicities.

Vichaya EG, Chiu GS, Krukowski K, Lacourt TE, Kavelaars A, Dantzer R, Heijnen CJ, Walker AK.

Front Neurosci. 2015 Apr 21;9:131. doi: 10.3389/fnins.2015.00131. eCollection 2015. Review.

40.

Analytical workflow profiling gene expression in murine macrophages.

Nixon SE, González-Peña D, Lawson MA, McCusker RH, Hernandez AG, O'Connor JC, Dantzer R, Kelley KW, Rodriguez-Zas SL.

J Bioinform Comput Biol. 2015 Apr;13(2):1550010. doi: 10.1142/S0219720015500109. Epub 2015 Jan 14.

41.

Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder.

Savitz J, Drevets WC, Wurfel BE, Ford BN, Bellgowan PS, Victor TA, Bodurka J, Teague TK, Dantzer R.

Brain Behav Immun. 2015 May;46:55-9. doi: 10.1016/j.bbi.2015.02.007. Epub 2015 Feb 14.

42.

Peripheral indoleamine 2,3-dioxygenase 1 is required for comorbid depression-like behavior but does not contribute to neuropathic pain in mice.

Zhou W, Dantzer R, Budac DP, Walker AK, Mao-Ying QL, Lee AW, Heijnen CJ, Kavelaars A.

Brain Behav Immun. 2015 May;46:147-53. doi: 10.1016/j.bbi.2015.01.013. Epub 2015 Jan 28.

43.

Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorder.

Savitz J, Dantzer R, Wurfel BE, Victor TA, Ford BN, Bodurka J, Bellgowan PS, Teague TK, Drevets WC.

Psychoneuroendocrinology. 2015 Feb;52:200-11. doi: 10.1016/j.psyneuen.2014.11.015. Epub 2014 Nov 24.

44.

Advancing the understanding of behaviors associated with Bacille Calmette Guérin infection using multivariate analysis.

Rodriguez-Zas SL, Nixon SE, Lawson MA, Mccusker RH, Southey BR, O'Connor JC, Dantzer R, Kelley KW.

Brain Behav Immun. 2015 Feb;44:176-86. doi: 10.1016/j.bbi.2014.09.018. Epub 2014 Oct 7.

45.

Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder.

Savitz J, Drevets WC, Smith CM, Victor TA, Wurfel BE, Bellgowan PS, Bodurka J, Teague TK, Dantzer R.

Neuropsychopharmacology. 2015 Jan;40(2):463-71. doi: 10.1038/npp.2014.194. Epub 2014 Jul 30.

46.

Lipopolysaccharide reduces incentive motivation while boosting preference for high reward in mice.

Vichaya EG, Hunt SC, Dantzer R.

Neuropsychopharmacology. 2014 Nov;39(12):2884-90. doi: 10.1038/npp.2014.141. Epub 2014 Jun 11.

47.

Is there a role for glutamate-mediated excitotoxicity in inflammation-induced depression?

Dantzer R, Walker AK.

J Neural Transm (Vienna). 2014 Aug;121(8):925-32. doi: 10.1007/s00702-014-1187-1. Epub 2014 Mar 15. Review.

48.

Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands.

Alfaro VY, Goldblatt DL, Valverde GR, Munsell MF, Quinton LJ, Walker AK, Dantzer R, Varadhachary A, Scott BL, Evans SE, Tuvim MJ, Dickey BF.

Front Pharmacol. 2014 Feb 6;5:8. doi: 10.3389/fphar.2014.00008. eCollection 2014.

49.

Activation of lung toll-like receptors does not exacerbate sickness responses to lipopolysaccharide in mice.

Walker AK, Hsieh J, Luu KV, Radwan AA, Valverde GR, Dickey BF, Tuvim MJ, Dantzer R.

Brain Behav Immun. 2014 May;38:211-9. doi: 10.1016/j.bbi.2014.02.004. Epub 2014 Feb 15.

50.

Elevated levels of plasma phenylalanine in schizophrenia: a guanosine triphosphate cyclohydrolase-1 metabolic pathway abnormality?

Okusaga O, Muravitskaja O, Fuchs D, Ashraf A, Hinman S, Giegling I, Hartmann AM, Konte B, Friedl M, Schiffman J, Hong E, Reeves G, Groer M, Dantzer R, Rujescu D, Postolache TT.

PLoS One. 2014 Jan 21;9(1):e85945. doi: 10.1371/journal.pone.0085945. eCollection 2014.

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