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Items: 1 to 50 of 75

1.

PARP1 and Poly(ADP-ribosyl)ation Signaling during Autophagy in Response to Nutrient Deprivation.

Rodríguez-Vargas JM, Oliver-Pozo FJ, Dantzer F.

Oxid Med Cell Longev. 2019 Jun 9;2019:2641712. doi: 10.1155/2019/2641712. eCollection 2019. Review.

2.

Therapeutic considerations of PARP in stem cell biology: Relevance in cancer and beyond.

Zeniou M, Nguekeu-Zebaze L, Dantzer F.

Biochem Pharmacol. 2019 Sep;167:107-115. doi: 10.1016/j.bcp.2019.06.012. Epub 2019 Jun 13. Review.

PMID:
31202733
3.

PARP3 comes to light as a prime target in cancer therapy.

Rodriguez-Vargas JM, Nguekeu-Zebaze L, Dantzer F.

Cell Cycle. 2019 Jun;18(12):1295-1301. doi: 10.1080/15384101.2019.1617454. Epub 2019 May 29.

PMID:
31095444
4.

Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function.

Galindo-Campos MA, Bedora-Faure M, Farrés J, Lescale C, Moreno-Lama L, Martínez C, Martín-Caballero J, Ampurdanés C, Aparicio P, Dantzer F, Cerutti A, Deriano L, Yélamos J.

Cell Death Differ. 2019 Dec;26(12):2667-2681. doi: 10.1038/s41418-019-0326-5. Epub 2019 Apr 17.

5.

PARP3, a new therapeutic target to alter Rictor/mTORC2 signaling and tumor progression in BRCA1-associated cancers.

Beck C, Rodriguez-Vargas JM, Boehler C, Robert I, Heyer V, Hanini N, Gauthier LR, Tissier A, Schreiber V, Elofsson M, Reina San Martin B, Dantzer F.

Cell Death Differ. 2019 Sep;26(9):1615-1630. doi: 10.1038/s41418-018-0233-1. Epub 2018 Nov 15.

PMID:
30442946
6.

PARP2 mediates branched poly ADP-ribosylation in response to DNA damage.

Chen Q, Kassab MA, Dantzer F, Yu X.

Nat Commun. 2018 Aug 13;9(1):3233. doi: 10.1038/s41467-018-05588-5.

7.

PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression.

Dörsam B, Seiwert N, Foersch S, Stroh S, Nagel G, Begaliew D, Diehl E, Kraus A, McKeague M, Minneker V, Roukos V, Reißig S, Waisman A, Moehler M, Stier A, Mangerich A, Dantzer F, Kaina B, Fahrer J.

Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4061-E4070. doi: 10.1073/pnas.1712345115. Epub 2018 Apr 9.

8.

PARP2 deficiency affects invariant-NKT-cell maturation and protects mice from concanavalin A-induced liver injury.

Filliol A, Piquet-Pellorce C, Dion S, Genet V, Lucas-Clerc C, Dantzer F, Samson M.

Am J Physiol Gastrointest Liver Physiol. 2017 Nov 1;313(5):G399-G409. doi: 10.1152/ajpgi.00436.2016. Epub 2017 Jul 27.

9.

Purification of Recombinant Human PARG and Activity Assays.

Amé JC, Héberlé É, Camuzeaux B, Dantzer F, Schreiber V.

Methods Mol Biol. 2017;1608:395-413. doi: 10.1007/978-1-4939-6993-7_25.

PMID:
28695523
10.

Purification of Recombinant Human PARP-3.

Amé JC, Camuzeaux B, Dantzer F, Schreiber V.

Methods Mol Biol. 2017;1608:373-394. doi: 10.1007/978-1-4939-6993-7_24.

PMID:
28695522
11.

PARP-1/PARP-2 double deficiency in mouse T cells results in faulty immune responses and T lymphomas.

Navarro J, Gozalbo-López B, Méndez AC, Dantzer F, Schreiber V, Martínez C, Arana DM, Farrés J, Revilla-Nuin B, Bueno MF, Ampurdanés C, Galindo-Campos MA, Knobel PA, Segura-Bayona S, Martin-Caballero J, Stracker TH, Aparicio P, Del Val M, Yélamos J.

Sci Rep. 2017 Feb 9;7:41962. doi: 10.1038/srep41962.

12.

Robust immunoglobulin class switch recombination and end joining in Parp9-deficient mice.

Robert I, Gaudot L, Yélamos J, Noll A, Wong HK, Dantzer F, Schreiber V, Reina-San-Martin B.

Eur J Immunol. 2017 Apr;47(4):665-676. doi: 10.1002/eji.201646757. Epub 2017 Feb 22.

13.

Autophagy requires poly(adp-ribosyl)ation-dependent AMPK nuclear export.

Rodríguez-Vargas JM, Rodríguez MI, Majuelos-Melguizo J, García-Diaz Á, González-Flores A, López-Rivas A, Virág L, Illuzzi G, Schreiber V, Dantzer F, Oliver FJ.

Cell Death Differ. 2016 Dec;23(12):2007-2018. doi: 10.1038/cdd.2016.80. Epub 2016 Sep 30.

14.

Expanding functions of ADP-ribosylation in the maintenance of genome integrity.

Martin-Hernandez K, Rodriguez-Vargas JM, Schreiber V, Dantzer F.

Semin Cell Dev Biol. 2017 Mar;63:92-101. doi: 10.1016/j.semcdb.2016.09.009. Epub 2016 Sep 23. Review.

PMID:
27670719
15.

PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis.

Karicheva O, Rodriguez-Vargas JM, Wadier N, Martin-Hernandez K, Vauchelles R, Magroun N, Tissier A, Schreiber V, Dantzer F.

Oncotarget. 2016 Sep 27;7(39):64109-64123. doi: 10.18632/oncotarget.11627.

16.

PARG deficiency is neither synthetic lethal with BRCA1 nor PTEN deficiency.

Noll A, Illuzzi G, Amé JC, Dantzer F, Schreiber V.

Cancer Cell Int. 2016 Jul 1;16:53. doi: 10.1186/s12935-016-0333-2. eCollection 2016.

17.

A PARP1-ERK2 synergism is required for the induction of LTP.

Visochek L, Grigoryan G, Kalal A, Milshtein-Parush H, Gazit N, Slutsky I, Yeheskel A, Shainberg A, Castiel A, Seger R, Langelier MF, Dantzer F, Pascal JM, Segal M, Cohen-Armon M.

Sci Rep. 2016 Apr 28;6:24950. doi: 10.1038/srep24950.

18.

Distinct mechanisms for opposite functions of homeoproteins Cdx2 and HoxB7 in double-strand break DNA repair in colon cancer cells.

Soret C, Martin E, Duluc I, Dantzer F, Vanier M, Gross I, Freund JN, Domon-Dell C.

Cancer Lett. 2016 May 1;374(2):208-15. doi: 10.1016/j.canlet.2016.02.026. Epub 2016 Feb 19.

PMID:
26902420
19.

[From poly(ADP-ribose) discovery to PARP inhibitors in cancer therapy].

Schreiber V, Illuzzi G, Héberlé E, Dantzer F.

Bull Cancer. 2015 Oct;102(10):863-73. doi: 10.1016/j.bulcan.2015.07.012. Epub 2015 Sep 15. Review. French.

PMID:
26384693
20.

Parp3 negatively regulates immunoglobulin class switch recombination.

Robert I, Gaudot L, Rogier M, Heyer V, Noll A, Dantzer F, Reina-San-Martin B.

PLoS Genet. 2015 May 22;11(5):e1005240. doi: 10.1371/journal.pgen.1005240. eCollection 2015 May.

21.

PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors.

Farrés J, Llacuna L, Martin-Caballero J, Martínez C, Lozano JJ, Ampurdanés C, López-Contreras AJ, Florensa L, Navarro J, Ottina E, Dantzer F, Schreiber V, Villunger A, Fernández-Capetillo O, Yélamos J.

Cell Death Differ. 2015 Jul;22(7):1144-57. doi: 10.1038/cdd.2014.202. Epub 2014 Dec 12.

22.

Poly(ADP-ribose) polymerases in double-strand break repair: focus on PARP1, PARP2 and PARP3.

Beck C, Robert I, Reina-San-Martin B, Schreiber V, Dantzer F.

Exp Cell Res. 2014 Nov 15;329(1):18-25. doi: 10.1016/j.yexcr.2014.07.003. Epub 2014 Jul 10. Review.

PMID:
25017100
23.

PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress.

Illuzzi G, Fouquerel E, Amé JC, Noll A, Rehmet K, Nasheuer HP, Dantzer F, Schreiber V.

Nucleic Acids Res. 2014 Jul;42(12):7776-92. doi: 10.1093/nar/gku505. Epub 2014 Jun 6.

24.

NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease.

Cerutti R, Pirinen E, Lamperti C, Marchet S, Sauve AA, Li W, Leoni V, Schon EA, Dantzer F, Auwerx J, Viscomi C, Zeviani M.

Cell Metab. 2014 Jun 3;19(6):1042-9. doi: 10.1016/j.cmet.2014.04.001. Epub 2014 May 8.

25.

Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functions.

De Vos M, El Ramy R, Quénet D, Wolf P, Spada F, Magroun N, Babbio F, Schreiber V, Leonhardt H, Bonapace IM, Dantzer F.

J Biol Chem. 2014 Jun 6;289(23):16223-38. doi: 10.1074/jbc.M113.527424. Epub 2014 Apr 29.

26.

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.

Beck C, Boehler C, Guirouilh Barbat J, Bonnet ME, Illuzzi G, Ronde P, Gauthier LR, Magroun N, Rajendran A, Lopez BS, Scully R, Boussin FD, Schreiber V, Dantzer F.

Nucleic Acids Res. 2014 May;42(9):5616-32. doi: 10.1093/nar/gku174. Epub 2014 Mar 5.

27.

Cell death associated with abnormal mitosis observed by confocal imaging in live cancer cells.

Castiel A, Visochek L, Mittelman L, Zilberstein Y, Dantzer F, Izraeli S, Cohen-Armon M.

J Vis Exp. 2013 Aug 21;(78):e50568. doi: 10.3791/50568.

28.

The expanding role of PARPs in the establishment and maintenance of heterochromatin.

Dantzer F, Santoro R.

FEBS J. 2013 Aug;280(15):3508-18. doi: 10.1111/febs.12368. Epub 2013 Jun 27. Review.

29.

Parp-2 is required to maintain hematopoiesis following sublethal γ-irradiation in mice.

Farrés J, Martín-Caballero J, Martínez C, Lozano JJ, Llacuna L, Ampurdanés C, Ruiz-Herguido C, Dantzer F, Schreiber V, Villunger A, Bigas A, Yélamos J.

Blood. 2013 Jul 4;122(1):44-54. doi: 10.1182/blood-2012-12-472845. Epub 2013 May 15.

30.

Functional aspects of PARylation in induced and programmed DNA repair processes: preserving genome integrity and modulating physiological events.

Robert I, Karicheva O, Reina San Martin B, Schreiber V, Dantzer F.

Mol Aspects Med. 2013 Dec;34(6):1138-52. doi: 10.1016/j.mam.2013.02.001. Epub 2013 Feb 26. Review.

PMID:
23454615
31.

The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage.

Legrand AJ, Choul-Li S, Spriet C, Idziorek T, Vicogne D, Drobecq H, Dantzer F, Villeret V, Aumercier M.

PLoS One. 2013;8(2):e55883. doi: 10.1371/journal.pone.0055883. Epub 2013 Feb 6.

32.

Decreasing Poly(ADP-Ribose) Polymerase Activity Restores ΔF508 CFTR Trafficking.

Anjos SM, Robert R, Waller D, Zhang DL, Balghi H, Sampson HM, Ciciriello F, Lesimple P, Carlile GW, Goepp J, Liao J, Ferraro P, Phillipe R, Dantzer F, Hanrahan JW, Thomas DY.

Front Pharmacol. 2012 Sep 12;3:165. doi: 10.3389/fphar.2012.00165. eCollection 2012.

33.

New readers and interpretations of poly(ADP-ribosyl)ation.

Kalisch T, Amé JC, Dantzer F, Schreiber V.

Trends Biochem Sci. 2012 Sep;37(9):381-90. doi: 10.1016/j.tibs.2012.06.001. Epub 2012 Jul 3. Review.

PMID:
22766145
34.

The diverse roles and clinical relevance of PARPs in DNA damage repair: current state of the art.

De Vos M, Schreiber V, Dantzer F.

Biochem Pharmacol. 2012 Jul 15;84(2):137-46. doi: 10.1016/j.bcp.2012.03.018. Epub 2012 Mar 31. Review.

PMID:
22469522
35.

A phenanthrene derived PARP inhibitor is an extra-centrosomes de-clustering agent exclusively eradicating human cancer cells.

Castiel A, Visochek L, Mittelman L, Dantzer F, Izraeli S, Cohen-Armon M.

BMC Cancer. 2011 Sep 26;11:412. doi: 10.1186/1471-2407-11-412.

36.

Phenotypic characterization of Parp-1 and Parp-2 deficient mice and cells.

Boehler C, Gauthier L, Yelamos J, Noll A, Schreiber V, Dantzer F.

Methods Mol Biol. 2011;780:313-36. doi: 10.1007/978-1-61779-270-0_19.

PMID:
21870269
37.

Purification of recombinant poly(ADP-ribose) polymerases.

Amé JC, Kalisch T, Dantzer F, Schreiber V.

Methods Mol Biol. 2011;780:135-52. doi: 10.1007/978-1-61779-270-0_9.

PMID:
21870259
38.

Poly(ADP-ribose)-dependent regulation of Snail1 protein stability.

Rodríguez MI, González-Flores A, Dantzer F, Collard J, de Herreros AG, Oliver FJ.

Oncogene. 2011 Oct 20;30(42):4365-72. doi: 10.1038/onc.2011.153. Epub 2011 May 16.

PMID:
21577210
39.

[PARP inhibitors: significant progress in cancer therapy].

Dantzer F, Noel G, Schreiber V.

Bull Cancer. 2011 Mar;98(3):277-90. doi: 10.1684/bdc.2011.1330. Review. French.

40.

PARP-3, a DNA-dependent PARP with emerging roles in double-strand break repair and mitotic progression.

Boehler C, Dantzer F.

Cell Cycle. 2011 Apr 1;10(7):1023-4. Epub 2011 Apr 1. No abstract available.

PMID:
21358266
41.

Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression.

Boehler C, Gauthier LR, Mortusewicz O, Biard DS, Saliou JM, Bresson A, Sanglier-Cianferani S, Smith S, Schreiber V, Boussin F, Dantzer F.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2783-8. doi: 10.1073/pnas.1016574108. Epub 2011 Jan 26.

42.

Pharmacological inhibition of poly(ADP-ribose) polymerase (PARP) activity in PARP-1 silenced tumour cells increases chemosensitivity to temozolomide and to a N3-adenine selective methylating agent.

Tentori L, Muzi A, Dorio AS, Scarsella M, Leonetti C, Shah GM, Xu W, Camaioni E, Gold B, Pellicciari R, Dantzer F, Zhang J, Graziani G.

Curr Cancer Drug Targets. 2010 Jun;10(4):368-83.

PMID:
20464779
43.

Loss of poly(ADP-ribose) polymerase-2 leads to rapid development of spontaneous T-cell lymphomas in p53-deficient mice.

Nicolás L, Martínez C, Baró C, Rodríguez M, Baroja-Mazo A, Sole F, Flores JM, Ampurdanés C, Dantzer F, Martin-Caballero J, Aparicio P, Yelamos J.

Oncogene. 2010 May 13;29(19):2877-83. doi: 10.1038/onc.2010.11. Epub 2010 Feb 15.

PMID:
20154718
44.

A selective eradication of human nonhereditary breast cancer cells by phenanthridine-derived polyADP-ribose polymerase inhibitors.

Inbar-Rozensal D, Castiel A, Visochek L, Castel D, Dantzer F, Izraeli S, Cohen-Armon M.

Breast Cancer Res. 2009;11(6):R78. doi: 10.1186/bcr2445. Epub 2009 Nov 9.

45.

Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes.

El Ramy R, Magroun N, Messadecq N, Gauthier LR, Boussin FD, Kolthur-Seetharam U, Schreiber V, McBurney MW, Sassone-Corsi P, Dantzer F.

Cell Mol Life Sci. 2009 Oct;66(19):3219-34. doi: 10.1007/s00018-009-0105-4. Epub 2009 Aug 12.

PMID:
19672559
46.

Parp2 is required for the differentiation of post-meiotic germ cells: identification of a spermatid-specific complex containing Parp1, Parp2, TP2 and HSPA2.

Quénet D, Mark M, Govin J, van Dorsselear A, Schreiber V, Khochbin S, Dantzer F.

Exp Cell Res. 2009 Oct 1;315(16):2824-34. doi: 10.1016/j.yexcr.2009.07.003. Epub 2009 Jul 14.

PMID:
19607827
47.

Radiation-induced mitotic catastrophe in PARG-deficient cells.

Amé JC, Fouquerel E, Gauthier LR, Biard D, Boussin FD, Dantzer F, de Murcia G, Schreiber V.

J Cell Sci. 2009 Jun 15;122(Pt 12):1990-2002. doi: 10.1242/jcs.039115. Epub 2009 May 19.

48.

Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination.

Robert I, Dantzer F, Reina-San-Martin B.

J Exp Med. 2009 May 11;206(5):1047-56. doi: 10.1084/jem.20082468. Epub 2009 Apr 13.

49.

Hsp70 translocates to the nuclei and nucleoli, binds to XRCC1 and PARP-1, and protects HeLa cells from single-strand DNA breaks.

Kotoglou P, Kalaitzakis A, Vezyraki P, Tzavaras T, Michalis LK, Dantzer F, Jung JU, Angelidis C.

Cell Stress Chaperones. 2009 Jul;14(4):391-406. doi: 10.1007/s12192-008-0093-6. Epub 2008 Dec 17.

50.

Detection of the nuclear poly(ADP-ribose)-metabolizing enzymes and activities in response to DNA damage.

Amé JC, Hakmé A, Quenet D, Fouquerel E, Dantzer F, Schreiber V.

Methods Mol Biol. 2009;464:267-83. doi: 10.1007/978-1-60327-461-6_15.

PMID:
18951190

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