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Items: 1 to 50 of 124

1.

Inhibition of extracellular proteases improves the production of a xylanase in Parageobacillus thermoglucosidasius.

Holland ATN, Danson MJ, Bolhuis A.

BMC Biotechnol. 2019 Mar 20;19(1):17. doi: 10.1186/s12896-019-0511-0.

2.

Kawasaki disease: a prospective population survey in the UK and Ireland from 2013 to 2015.

Tulloh RMR, Mayon-White R, Harnden A, Ramanan AV, Tizard EJ, Shingadia D, Michie CA, Lynn RM, Levin M, Franklin OD, Craggs P, Davidson S, Stirzaker R, Danson M, Brogan PA.

Arch Dis Child. 2019 Jul;104(7):640-646. doi: 10.1136/archdischild-2018-315087. Epub 2018 Aug 13.

PMID:
30104394
3.

Insights into the Substrate Specificity of Archaeal Entner-Doudoroff Aldolases: The Structures of Picrophilus torridus 2-Keto-3-deoxygluconate Aldolase and Sulfolobus solfataricus 2-Keto-3-deoxy-6-phosphogluconate Aldolase in Complex with 2-Keto-3-deoxy-6-phosphogluconate.

Zaitsev V, Johnsen U, Reher M, Ortjohann M, Taylor GL, Danson MJ, Schönheit P, Crennell SJ.

Biochemistry. 2018 Jul 3;57(26):3797-3806. doi: 10.1021/acs.biochem.8b00535. Epub 2018 Jun 13.

PMID:
29812914
4.

Crystal structure of an inferred ancestral bacterial pyruvate decarboxylase.

Buddrus L, Andrews ESV, Leak DJ, Danson MJ, Arcus VL, Crennell SJ.

Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74(Pt 3):179-186. doi: 10.1107/S2053230X18002819. Epub 2018 Feb 26.

5.

Diversity of bacteria and archaea from two shallow marine hydrothermal vents from Vulcano Island.

Antranikian G, Suleiman M, Schäfers C, Adams MWW, Bartolucci S, Blamey JM, Birkeland NK, Bonch-Osmolovskaya E, da Costa MS, Cowan D, Danson M, Forterre P, Kelly R, Ishino Y, Littlechild J, Moracci M, Noll K, Oshima T, Robb F, Rossi M, Santos H, Schönheit P, Sterner R, Thauer R, Thomm M, Wiegel J, Stetter KO.

Extremophiles. 2017 Jul;21(4):733-742. doi: 10.1007/s00792-017-0938-y. Epub 2017 May 10.

PMID:
28493148
6.

Development of an efficient technique for gene deletion and allelic exchange in Geobacillus spp.

Bacon LF, Hamley-Bennett C, Danson MJ, Leak DJ.

Microb Cell Fact. 2017 Apr 5;16(1):58. doi: 10.1186/s12934-017-0670-4.

7.

Structure of an acetylating aldehyde dehydrogenase from the thermophilic ethanologen Geobacillus thermoglucosidasius.

Extance J, Danson MJ, Crennell SJ.

Protein Sci. 2016 Nov;25(11):2045-2053. doi: 10.1002/pro.3027. Epub 2016 Sep 20.

8.

Crystal structure of pyruvate decarboxylase from Zymobacter palmae.

Buddrus L, Andrews ES, Leak DJ, Danson MJ, Arcus VL, Crennell SJ.

Acta Crystallogr F Struct Biol Commun. 2016 Sep;72(Pt 9):700-6. doi: 10.1107/S2053230X16012012. Epub 2016 Aug 26.

9.

Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex.

Marrott NL, Marshall JJ, Svergun DI, Crennell SJ, Hough DW, van den Elsen JM, Danson MJ.

Biochem J. 2014 Nov 1;463(3):405-12. doi: 10.1042/BJ20140359.

PMID:
25088564
10.

Structures of mesophilic and extremophilic citrate synthases reveal rigidity and flexibility for function.

Wells SA, Crennell SJ, Danson MJ.

Proteins. 2014 Oct;82(10):2657-70. doi: 10.1002/prot.24630. Epub 2014 Jun 28.

PMID:
24948467
11.

Draft Genome Sequences of Geobacillus sp. Strains CAMR5420 and CAMR12739.

De Maayer P, Williamson CE, Vennard CT, Danson MJ, Cowan DA.

Genome Announc. 2014 Jun 5;2(3). pii: e00567-14. doi: 10.1128/genomeA.00567-14.

12.

A novel β-xylosidase structure from Geobacillus thermoglucosidasius: the first crystal structure of a glycoside hydrolase family GH52 enzyme reveals unpredicted similarity to other glycoside hydrolase folds.

Espina G, Eley K, Pompidor G, Schneider TR, Crennell SJ, Danson MJ.

Acta Crystallogr D Biol Crystallogr. 2014 May;70(Pt 5):1366-74. doi: 10.1107/S1399004714002788. Epub 2014 Apr 30.

PMID:
24816105
13.

Comparative genomic analysis reveals 2-oxoacid dehydrogenase complex lipoylation correlation with aerobiosis in archaea.

Borziak K, Posner MG, Upadhyay A, Danson MJ, Bagby S, Dorus S.

PLoS One. 2014 Jan 28;9(1):e87063. doi: 10.1371/journal.pone.0087063. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e100680.

14.

Structure of a bifunctional alcohol dehydrogenase involved in bioethanol generation in Geobacillus thermoglucosidasius.

Extance J, Crennell SJ, Eley K, Cripps R, Hough DW, Danson MJ.

Acta Crystallogr D Biol Crystallogr. 2013 Oct;69(Pt 10):2104-15. doi: 10.1107/S0907444913020349. Epub 2013 Sep 20.

PMID:
24100328
15.

Temperature and the catalytic activity of enzymes: a fresh understanding.

Daniel RM, Danson MJ.

FEBS Lett. 2013 Sep 2;587(17):2738-43. doi: 10.1016/j.febslet.2013.06.027. Epub 2013 Jun 27. Review.

16.

Syntheses of 2-keto-3-deoxy-D-xylonate and 2-keto-3-deoxy-L-arabinonate as stereochemical probes for demonstrating the metabolic promiscuity of Sulfolobus solfataricus towards D-xylose and L-arabinose.

Archer RM, Royer SF, Mahy W, Winn CL, Danson MJ, Bull SD.

Chemistry. 2013 Feb 18;19(8):2895-902. doi: 10.1002/chem.201203489. Epub 2013 Jan 11.

PMID:
23315785
17.

Post-translational modification in the archaea: structural characterization of multi-enzyme complex lipoylation.

Posner MG, Upadhyay A, Crennell SJ, Watson AJ, Dorus S, Danson MJ, Bagby S.

Biochem J. 2013 Jan 15;449(2):415-25. doi: 10.1042/BJ20121150.

PMID:
23116157
18.

The catalytic core of an archaeal 2-oxoacid dehydrogenase multienzyme complex is a 42-mer protein assembly.

Marrott NL, Marshall JJ, Svergun DI, Crennell SJ, Hough DW, Danson MJ, van den Elsen JM.

FEBS J. 2012 Mar;279(5):713-23. doi: 10.1111/j.1742-4658.2011.08461.x. Epub 2012 Jan 19.

19.

Contribution of inter-subunit interactions to the thermostability of Pyrococcus furiosus citrate synthase.

Moore V, Kanu A, Byron O, Campbell G, Danson MJ, Hough DW, Crennell SJ.

Extremophiles. 2011 May;15(3):327-36. doi: 10.1007/s00792-011-0363-6. Epub 2011 Mar 20.

PMID:
21424517
20.

Metabolism of pentose sugars in the hyperthermophilic archaea Sulfolobus solfataricus and Sulfolobus acidocaldarius.

Nunn CE, Johnsen U, Schönheit P, Fuhrer T, Sauer U, Hough DW, Danson MJ.

J Biol Chem. 2010 Oct 29;285(44):33701-9. doi: 10.1074/jbc.M110.146332. Epub 2010 Aug 24.

21.

Structurally informed site-directed mutagenesis of a stereochemically promiscuous aldolase to afford stereochemically complementary biocatalysts.

Royer SF, Haslett L, Crennell SJ, Hough DW, Danson MJ, Bull SD.

J Am Chem Soc. 2010 Aug 25;132(33):11753-8. doi: 10.1021/ja104412a.

PMID:
20684556
22.

A new understanding of how temperature affects the catalytic activity of enzymes.

Daniel RM, Danson MJ.

Trends Biochem Sci. 2010 Oct;35(10):584-91. doi: 10.1016/j.tibs.2010.05.001. Epub 2010 Jun 16. Review.

PMID:
20554446
23.

Discovery of a putative acetoin dehydrogenase complex in the hyperthermophilic archaeon Sulfolobus solfataricus.

Payne KA, Hough DW, Danson MJ.

FEBS Lett. 2010 Mar 19;584(6):1231-4. doi: 10.1016/j.febslet.2010.02.037. Epub 2010 Feb 18.

24.

The molecular basis of the effect of temperature on enzyme activity.

Daniel RM, Peterson ME, Danson MJ, Price NC, Kelly SM, Monk CR, Weinberg CS, Oudshoorn ML, Lee CK.

Biochem J. 2009 Dec 23;425(2):353-60. doi: 10.1042/BJ20091254.

PMID:
19849667
25.

A unique lipoylation system in the Archaea. Lipoylation in Thermoplasma acidophilum requires two proteins.

Posner MG, Upadhyay A, Bagby S, Hough DW, Danson MJ.

FEBS J. 2009 Aug;276(15):4012-22. doi: 10.1111/j.1742-4658.2009.07110.x. Epub 2009 Jul 7.

26.

The structure of Sulfolobus solfataricus 2-keto-3-deoxygluconate kinase.

Potter JA, Kerou M, Lamble HJ, Bull SD, Hough DW, Danson MJ, Taylor GL.

Acta Crystallogr D Biol Crystallogr. 2008 Dec;64(Pt 12):1283-7. doi: 10.1107/S0907444908036111. Epub 2008 Nov 18.

PMID:
19018105
27.

Nitroreductase from Bacillus licheniformis: a stable enzyme for prodrug activation.

Emptage CD, Knox RJ, Danson MJ, Hough DW.

Biochem Pharmacol. 2009 Jan 1;77(1):21-9. doi: 10.1016/j.bcp.2008.09.010. Epub 2008 Sep 17.

PMID:
18840409
28.

New parameters controlling the effect of temperature on enzyme activity.

Daniel RM, Danson MJ, Eisenthal R, Lee CK, Peterson ME.

Biochem Soc Trans. 2007 Dec;35(Pt 6):1543-6. Review.

PMID:
18031263
29.

The 2-oxoacid dehydrogenase multi-enzyme complex of the archaeon Thermoplasma acidophilum - recombinant expression, assembly and characterization.

Heath C, Posner MG, Aass HC, Upadhyay A, Scott DJ, Hough DW, Danson MJ.

FEBS J. 2007 Oct;274(20):5406-15. Epub 2007 Sep 26.

30.

The effect of temperature on enzyme activity: new insights and their implications.

Daniel RM, Danson MJ, Eisenthal R, Lee CK, Peterson ME.

Extremophiles. 2008 Jan;12(1):51-9. Epub 2007 Sep 13. Review.

PMID:
17849082
31.

The 2-oxoacid dehydrogenase multienzyme complex of Haloferax volcanii.

Al-Mailem DM, Hough DW, Danson MJ.

Extremophiles. 2008 Jan;12(1):89-96. Epub 2007 Jun 15.

PMID:
17571210
32.

Catalytic efficiency and kcat/KM: a useful comparator?

Eisenthal R, Danson MJ, Hough DW.

Trends Biotechnol. 2007 Jun;25(6):247-9. Epub 2007 Apr 12.

PMID:
17433847
33.

Eurythermalism and the temperature dependence of enzyme activity.

Lee CK, Daniel RM, Shepherd C, Saul D, Cary SC, Danson MJ, Eisenthal R, Peterson ME.

FASEB J. 2007 Jun;21(8):1934-41. Epub 2007 Mar 6.

PMID:
17341686
34.

Community surveys and risk factor analysis of human alveolar and cystic echinococcosis in Ningxia Hui Autonomous Region, China.

Yang YR, Sun T, Li Z, Zhang J, Teng J, Liu X, Liu R, Zhao R, Jones MK, Wang Y, Wen H, Feng X, Zhao Q, Zhao Y, Shi D, Bartholomot B, Vuitton DA, Pleydell D, Giraudoux P, Ito A, Danson MF, Boufana B, Craig PS, Williams GM, McManus DP.

Bull World Health Organ. 2006 Sep;84(9):714-21. Erratum in: Bull World Health Organ. 2006 Oct;84(10):840.

35.

The dependence of enzyme activity on temperature: determination and validation of parameters.

Peterson ME, Daniel RM, Danson MJ, Eisenthal R.

Biochem J. 2007 Mar 1;402(2):331-7. Erratum in: Biochem J. 2007 May1:403(3):615.

36.

The thermal behaviour of enzyme activity: implications for biotechnology.

Eisenthal R, Peterson ME, Daniel RM, Danson MJ.

Trends Biotechnol. 2006 Jul;24(7):289-92. Epub 2006 Jun 6.

PMID:
16759724
37.

The structural basis of substrate promiscuity in glucose dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus.

Milburn CC, Lamble HJ, Theodossis A, Bull SD, Hough DW, Danson MJ, Taylor GL.

J Biol Chem. 2006 May 26;281(21):14796-804. Epub 2006 Mar 23.

38.

Preliminary crystallographic studies of glucose dehydrogenase from the promiscuous Entner-Doudoroff pathway in the hyperthermophilic archaeon Sulfolobus solfataricus.

Theodossis A, Milburn CC, Heyer NI, Lamble HJ, Hough DW, Danson MJ, Taylor GL.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jan 1;61(Pt 1):112-5. Epub 2004 Dec 24.

39.

Promiscuity in the part-phosphorylative Entner-Doudoroff pathway of the archaeon Sulfolobus solfataricus.

Lamble HJ, Theodossis A, Milburn CC, Taylor GL, Bull SD, Hough DW, Danson MJ.

FEBS Lett. 2005 Dec 19;579(30):6865-9. Epub 2005 Dec 1.

40.

Engineering stereocontrol into an aldolase-catalysed reaction.

Lamble HJ, Danson MJ, Hough DW, Bull SD.

Chem Commun (Camb). 2005 Jan 7;(1):124-6. Epub 2004 Nov 23.

PMID:
15614394
42.

Gluconate dehydratase from the promiscuous Entner-Doudoroff pathway in Sulfolobus solfataricus.

Lamble HJ, Milburn CC, Taylor GL, Hough DW, Danson MJ.

FEBS Lett. 2004 Oct 8;576(1-2):133-6.

43.

The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus.

Theodossis A, Walden H, Westwick EJ, Connaris H, Lamble HJ, Hough DW, Danson MJ, Taylor GL.

J Biol Chem. 2004 Oct 15;279(42):43886-92. Epub 2004 Jul 20.

44.

A new intrinsic thermal parameter for enzymes reveals true temperature optima.

Peterson ME, Eisenthal R, Danson MJ, Spence A, Daniel RM.

J Biol Chem. 2004 May 14;279(20):20717-22. Epub 2004 Feb 18. Erratum in: J Biol Chem. 2005 Dec 16;280(50):41784.

45.

Metabolic pathway promiscuity in the archaeon Sulfolobus solfataricus revealed by studies on glucose dehydrogenase and 2-keto-3-deoxygluconate aldolase.

Lamble HJ, Heyer NI, Bull SD, Hough DW, Danson MJ.

J Biol Chem. 2003 Sep 5;278(36):34066-72. Epub 2003 Jun 24.

46.

Use of a packed-column bioreactor for isolation of diverse protease-producing bacteria from antarctic soil.

Wery N, Gerike U, Sharman A, Chaudhuri JB, Hough DW, Danson MJ.

Appl Environ Microbiol. 2003 Mar;69(3):1457-64.

47.

Citrate synthase from Thermus aquaticus: a thermostable bacterial enzyme with a five-membered inter-subunit ionic network.

Nordberg Karlsson E, Crennell SJ, Higgins C, Nawaz S, Yeoh L, Hough DW, Danson MJ.

Extremophiles. 2003 Feb;7(1):9-16. Epub 2002 Sep 7.

PMID:
12579375
48.

Stepwise adaptations of citrate synthase to survival at life's extremes. From psychrophile to hyperthermophile.

Bell GS, Russell RJ, Connaris H, Hough DW, Danson MJ, Taylor GL.

Eur J Biochem. 2002 Dec;269(24):6250-60.

49.

Rhodothermus marinus: a thermophilic bacterium producing dimeric and hexameric citrate synthase isoenzymes.

Nordberg KE, Abou-Hachem M, Holst O, Danson MJ, Hough DW.

Extremophiles. 2002 Feb;6(1):51-6.

PMID:
11878562
50.

Cold-active citrate synthase: mutagenesis of active-site residues.

Gerike U, Danson MJ, Hough DW.

Protein Eng. 2001 Sep;14(9):655-61.

PMID:
11707611

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