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Items: 1 to 50 of 66

1.

Association of HLA-dependent islet autoimmunity with systemic antibody responses to intestinal commensal bacteria in children.

Paun A, Yau C, Meshkibaf S, Daigneault MC, Marandi L, Mortin-Toth S, Bar-Or A, Allen-Vercoe E, Poussier P, Danska JS.

Sci Immunol. 2019 Feb 1;4(32). pii: eaau8125. doi: 10.1126/sciimmunol.aau8125.

PMID:
30709843
2.

Common ground: shared risk factors for type 1 diabetes and celiac disease.

Verdu EF, Danska JS.

Nat Immunol. 2018 Jul;19(7):685-695. doi: 10.1038/s41590-018-0130-2. Epub 2018 Jun 20. Review.

PMID:
29925984
3.

Sex Effects at the Ramparts: Nutrient- and Microbe-Mediated Regulation of the Immune-Metabolic Interface.

Israelian N, Danska JS.

Adv Exp Med Biol. 2017;1043:113-140. doi: 10.1007/978-3-319-70178-3_7. Review.

PMID:
29224093
4.

Donor SIRPα polymorphism modulates the innate immune response to allogeneic grafts.

Dai H, Friday AJ, Abou-Daya KI, Williams AL, Mortin-Toth S, Nicotra ML, Rothstein DM, Shlomchik WD, Matozaki T, Isenberg JS, Oberbarnscheidt MH, Danska JS, Lakkis FG.

Sci Immunol. 2017 Jun 23;2(12). pii: eaam6202. doi: 10.1126/sciimmunol.aam6202.

5.

SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin.

Chen J, Zhong MC, Guo H, Davidson D, Mishel S, Lu Y, Rhee I, Pérez-Quintero LA, Zhang S, Cruz-Munoz ME, Wu N, Vinh DC, Sinha M, Calderon V, Lowell CA, Danska JS, Veillette A.

Nature. 2017 Apr 27;544(7651):493-497. doi: 10.1038/nature22076. Epub 2017 Apr 19.

6.

The Influence of the Microbiome on Type 1 Diabetes.

Paun A, Yau C, Danska JS.

J Immunol. 2017 Jan 15;198(2):590-595. doi: 10.4049/jimmunol.1601519. Review.

7.

Modulation of type 1 and type 2 diabetes risk by the intestinal microbiome.

Paun A, Danska JS.

Pediatr Diabetes. 2016 Nov;17(7):469-477. doi: 10.1111/pedi.12424. Epub 2016 Aug 3. Review.

PMID:
27484959
8.

Immune recognition and response to the intestinal microbiome in type 1 diabetes.

Paun A, Yau C, Danska JS.

J Autoimmun. 2016 Jul;71:10-8. doi: 10.1016/j.jaut.2016.02.004. Epub 2016 Feb 20. Review.

PMID:
26908163
9.

Immuno-ecology: how the microbiome regulates tolerance and autoimmunity.

Paun A, Danska JS.

Curr Opin Immunol. 2015 Dec;37:34-9. doi: 10.1016/j.coi.2015.09.004. Review.

PMID:
26460968
10.

Identification of the inflammasome Nlrp1b as the candidate gene conferring diabetes risk at the Idd4.1 locus in the nonobese diabetic mouse.

Motta VN, Markle JG, Gulban O, Mortin-Toth S, Liao KC, Mogridge J, Steward CA, Danska JS.

J Immunol. 2015 Jun 15;194(12):5663-73. doi: 10.4049/jimmunol.1400913. Epub 2015 May 11.

11.

Sex matters for mechanism.

Danska JS.

Sci Transl Med. 2014 Oct 15;6(258):258fs40. doi: 10.1126/scitranslmed.3009859.

PMID:
25320230
12.

Polymorphism in the innate immune receptor SIRPα controls CD47 binding and autoimmunity in the nonobese diabetic mouse.

Wong AS, Mortin-Toth S, Sung M, Canty AJ, Gulban O, Greaves DR, Danska JS.

J Immunol. 2014 Nov 15;193(10):4833-44. doi: 10.4049/jimmunol.1401984. Epub 2014 Oct 10.

13.

Microbiome manipulation modifies sex-specific risk for autoimmunity.

Markle JG, Frank DN, Adeli K, von Bergen M, Danska JS.

Gut Microbes. 2014 Jul 1;5(4):485-93. doi: 10.4161/gmic.29795. Epub 2014 Jul 9.

PMID:
25007153
14.

MuLV-related endogenous retroviral elements and Flt3 participate in aberrant end-joining events that promote B-cell leukemogenesis.

Johnson RM, Papp E, Grandal I, Kowalski PE, Nutter L, Wong RC, Joseph-George AM, Danska JS, Guidos CJ.

Genes Dev. 2014 Jun 1;28(11):1179-90. doi: 10.1101/gad.240820.114.

15.

Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.

Perova T, Grandal I, Nutter LM, Papp E, Matei IR, Beyene J, Kowalski PE, Hitzler JK, Minden MD, Guidos CJ, Danska JS.

Sci Transl Med. 2014 May 14;6(236):236ra62. doi: 10.1126/scitranslmed.3008661.

16.

SIRPα polymorphisms, but not the prion protein, control phagocytosis of apoptotic cells.

Nuvolone M, Kana V, Hutter G, Sakata D, Mortin-Toth SM, Russo G, Danska JS, Aguzzi A.

J Exp Med. 2013 Nov 18;210(12):2539-52. doi: 10.1084/jem.20131274. Epub 2013 Oct 21.

17.

γδ T cells are essential effectors of type 1 diabetes in the nonobese diabetic mouse model.

Markle JG, Mortin-Toth S, Wong AS, Geng L, Hayday A, Danska JS.

J Immunol. 2013 Jun 1;190(11):5392-401. doi: 10.4049/jimmunol.1203502. Epub 2013 Apr 26.

18.

Targeting SIRPα in cancer.

Ho JM, Danska JS, Wang JC.

Oncoimmunology. 2013 Feb 1;2(2):e23081.

19.

Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity.

Markle JG, Frank DN, Mortin-Toth S, Robertson CE, Feazel LM, Rolle-Kampczyk U, von Bergen M, McCoy KD, Macpherson AJ, Danska JS.

Science. 2013 Mar 1;339(6123):1084-8. doi: 10.1126/science.1233521. Epub 2013 Jan 17.

20.

Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts.

Theocharides AP, Jin L, Cheng PY, Prasolava TK, Malko AV, Ho JM, Poeppl AG, van Rooijen N, Minden MD, Danska JS, Dick JE, Wang JC.

J Exp Med. 2012 Sep 24;209(10):1883-99. Epub 2012 Sep 3.

21.

Generation and analysis of a mouse intestinal metatranscriptome through Illumina based RNA-sequencing.

Xiong X, Frank DN, Robertson CE, Hung SS, Markle J, Canty AJ, McCoy KD, Macpherson AJ, Poussier P, Danska JS, Parkinson J.

PLoS One. 2012;7(4):e36009. doi: 10.1371/journal.pone.0036009. Epub 2012 Apr 27.

22.

Stem cell gene expression programs influence clinical outcome in human leukemia.

Eppert K, Takenaka K, Lechman ER, Waldron L, Nilsson B, van Galen P, Metzeler KH, Poeppl A, Ling V, Beyene J, Canty AJ, Danska JS, Bohlander SK, Buske C, Minden MD, Golub TR, Jurisica I, Ebert BL, Dick JE.

Nat Med. 2011 Aug 28;17(9):1086-93. doi: 10.1038/nm.2415.

PMID:
21873988
23.

Maternal autoimmune thyroid disease and the fetal immune system.

Svensson J, Oderup C, Akesson C, Uvebrant K, Hallengren B, Ericsson UB, Arvastsson J, Danska JS, Lantz M, Cilio CM.

Exp Clin Endocrinol Diabetes. 2011 Jul;119(7):445-50. doi: 10.1055/s-0031-1279741. Epub 2011 Jun 10.

PMID:
21667438
24.

Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors.

Yuan JS, Tan JB, Visan I, Matei IR, Urbanellis P, Xu K, Danska JS, Egan SE, Guidos CJ.

Blood. 2011 Jan 27;117(4):1184-95. doi: 10.1182/blood-2010-07-296616. Epub 2010 Nov 19.

PMID:
21097675
25.

Glucagon-like peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells.

Hadjiyanni I, Siminovitch KA, Danska JS, Drucker DJ.

Diabetologia. 2010 Apr;53(4):730-40. Epub 2010 Jan 8.

PMID:
20225396
26.

After the GWAS rush: nuggets of insight into the pathogenesis of autoimmune disease.

Danska JS, Poussier P.

Semin Immunol. 2009 Dec;21(6):313-7. doi: 10.1016/j.smim.2009.10.007. Epub 2009 Nov 18. No abstract available.

PMID:
19926302
27.

Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.

Xu K, Nieuwenhuis E, Cohen BL, Wang W, Canty AJ, Danska JS, Coultas L, Rossant J, Wu MY, Piscione TD, Nagy A, Gossler A, Hicks GG, Hui CC, Henkelman RM, Yu LX, Sled JG, Gridley T, Egan SE.

Am J Physiol Lung Cell Mol Physiol. 2010 Jan;298(1):L45-56. doi: 10.1152/ajplung.90550.2008. Epub 2009 Nov 6.

28.

Molecular analysis of mouse T cell receptor expression using PCR.

Fox CJ, Danska JS.

Curr Protoc Immunol. 2001 May;Chapter 10:Unit 10.27. doi: 10.1002/0471142735.im1027s22. Review.

PMID:
18432692
29.

Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.

Takenaka K, Prasolava TK, Wang JC, Mortin-Toth SM, Khalouei S, Gan OI, Dick JE, Danska JS.

Nat Immunol. 2007 Dec;8(12):1313-23. Epub 2007 Nov 4.

PMID:
17982459
30.

Chromosomal reinsertion of broken RSS ends during T cell development.

Curry JD, Schulz D, Guidos CJ, Danska JS, Nutter L, Nussenzweig A, Schlissel MS.

J Exp Med. 2007 Oct 1;204(10):2293-303. Epub 2007 Sep 4.

31.

The idd4 locus displays sex-specific epistatic effects on type 1 diabetes susceptibility in nonobese diabetic mice.

Ivakine EA, Mortin-Toth SM, Gulban OM, Valova A, Canty A, Scott C, Danska JS.

Diabetes. 2006 Dec;55(12):3611-9.

32.

ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes.

Matei IR, Gladdy RA, Nutter LM, Canty A, Guidos CJ, Danska JS.

Blood. 2007 Mar 1;109(5):1887-96. Epub 2006 Oct 31.

PMID:
17077325
33.

p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc.

Gladdy RA, Nutter LM, Kunath T, Danska JS, Guidos CJ.

Mol Cancer Res. 2006 May;4(5):311-8.

34.

Molecular genetic analysis of the Idd4 locus implicates the IFN response in type 1 diabetes susceptibility in nonobese diabetic mice.

Ivakine EA, Gulban OM, Mortin-Toth SM, Wankiewicz E, Scott C, Spurrell D, Canty A, Danska JS.

J Immunol. 2006 Mar 1;176(5):2976-90.

35.

ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection.

Matei IR, Guidos CJ, Danska JS.

Immunol Rev. 2006 Feb;209:142-58. Review.

PMID:
16448540
36.

Sex-specific effect of insulin-dependent diabetes 4 on regulation of diabetes pathogenesis in the nonobese diabetic mouse.

Ivakine EA, Fox CJ, Paterson AD, Mortin-Toth SM, Canty A, Walton DS, Aleksa K, Ito S, Danska JS.

J Immunol. 2005 Jun 1;174(11):7129-40.

37.
38.

The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice.

Gladdy RA, Taylor MD, Williams CJ, Grandal I, Karaskova J, Squire JA, Rutka JT, Guidos CJ, Danska JS.

Cancer Cell. 2003 Jan;3(1):37-50.

39.

Susceptibility to lymphoid neoplasia in immunodeficient strains of nonobese diabetic mice.

Chiu PP, Ivakine E, Mortin-Toth S, Danska JS.

Cancer Res. 2002 Oct 15;62(20):5828-34.

40.

Genetic control of T and B lymphocyte activation in nonobese diabetic mice.

Chiu PP, Jevnikar AM, Danska JS.

J Immunol. 2001 Dec 15;167(12):7169-79.

41.
42.

Irradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors.

Williams CJ, Grandal I, Vesprini DJ, Wojtyra U, Danska JS, Guidos CJ.

Mol Cell Biol. 2001 Jan;21(2):400-13.

43.

Two genetic loci regulate T cell-dependent islet inflammation and drive autoimmune diabetes pathogenesis.

Fox CJ, Paterson AD, Mortin-Toth SM, Danska JS.

Am J Hum Genet. 2000 Jul;67(1):67-81. Epub 2000 Jun 9.

45.
46.
47.

Essential and perilous: V(D)J recombination and DNA damage checkpoints in lymphocyte precursors.

Danska JS, Guidos CJ.

Semin Immunol. 1997 Jun;9(3):199-206. Review.

PMID:
9200331
48.
49.

Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes.

Danska JS, Holland DP, Mariathasan S, Williams KM, Guidos CJ.

Mol Cell Biol. 1996 Oct;16(10):5507-17.

50.

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

Guidos CJ, Williams CJ, Grandal I, Knowles G, Huang MT, Danska JS.

Genes Dev. 1996 Aug 15;10(16):2038-54.

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