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Items: 36

1.

GLS hyperactivity causes glutamate excess, infantile cataract and profound developmental delay.

Rumping L, Tessadori F, Pouwels PJ, Vringer E, Wijnen JP, Bhogal AA, Savelberg SM, Duran KJ, Bakkers MJ, Ramos RJ, Schellekens PA, Kroes HY, Klomp DW, Black GC, Taylor RL, Bakkers JP, Prinsen HC, Knaap MS, Dansen TB, Rehmann H, Zwartkruis FJ, Houwen RH, Haaften G, Verhoeven-Duif NM, Jans JJ, Hasselt PM.

Hum Mol Genet. 2018 Sep 18. doi: 10.1093/hmg/ddy330. [Epub ahead of print]

PMID:
30239721
2.

FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression.

Hornsveld M, Smits LMM, Meerlo M, van Amersfoort M, Groot Koerkamp MJA, van Leenen D, Kloet DEA, Holstege FCP, Derksen PWB, Burgering BMT, Dansen TB.

Cancer Res. 2018 May 1;78(9):2356-2369. doi: 10.1158/0008-5472.CAN-17-2511. Epub 2018 Feb 12.

PMID:
29440168
3.

Re-evaluating the role of FOXOs in cancer.

Hornsveld M, Dansen TB, Derksen PW, Burgering BMT.

Semin Cancer Biol. 2018 Jun;50:90-100. doi: 10.1016/j.semcancer.2017.11.017. Epub 2017 Nov 21. Review.

4.

Proteome-wide Changes in Protein Turnover Rates in C. elegans Models of Longevity and Age-Related Disease.

Visscher M, De Henau S, Wildschut MHE, van Es RM, Dhondt I, Michels H, Kemmeren P, Nollen EA, Braeckman BP, Burgering BMT, Vos HR, Dansen TB.

Cell Rep. 2016 Sep 13;16(11):3041-3051. doi: 10.1016/j.celrep.2016.08.025.

5.

The Hallmarks of Cancer from a Redox Perspective.

Hornsveld M, Dansen TB.

Antioxid Redox Signal. 2016 Aug 20;25(6):300-25. doi: 10.1089/ars.2015.6580. Epub 2016 Aug 2. Review.

PMID:
27353526
6.

Restraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancer.

Hornsveld M, Tenhagen M, van de Ven RA, Smits AM, van Triest MH, van Amersfoort M, Kloet DE, Dansen TB, Burgering BM, Derksen PW.

Cell Death Differ. 2016 Sep 1;23(9):1483-92. doi: 10.1038/cdd.2016.33. Epub 2016 Apr 1.

7.

The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex.

van den Berg MC, van Gogh IJ, Smits AM, van Triest M, Dansen TB, Visscher M, Polderman PE, Vliem MJ, Rehmann H, Burgering BM.

J Biol Chem. 2016 Jan 15;291(3):1200. doi: 10.1074/jbc.A113.463885. No abstract available.

8.

Covalent targeting of acquired cysteines in cancer.

Visscher M, Arkin MR, Dansen TB.

Curr Opin Chem Biol. 2016 Feb;30:61-67. doi: 10.1016/j.cbpa.2015.11.004. Epub 2015 Nov 28. Review.

9.

Targeting FOXO1 as an option to treat obesity?

Dansen TB, Kalkhoven E.

Cell Cycle. 2015;14(16):2558. doi: 10.1080/15384101.2015.1060779. Epub 2015 Jun 11. No abstract available.

10.

Intermolecular disulfide-dependent redox signalling.

Putker M, Vos HR, Dansen TB.

Biochem Soc Trans. 2014 Aug;42(4):971-8. doi: 10.1042/BST20140097. Review.

PMID:
25109988
11.

Evolutionary acquisition of cysteines determines FOXO paralog-specific redox signaling.

Putker M, Vos HR, van Dorenmalen K, de Ruiter H, Duran AG, Snel B, Burgering BM, Vermeulen M, Dansen TB.

Antioxid Redox Signal. 2015 Jan 1;22(1):15-28. doi: 10.1089/ars.2014.6056.

12.

The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex.

van den Berg MC, van Gogh IJ, Smits AM, van Triest M, Dansen TB, Visscher M, Polderman PE, Vliem MJ, Rehmann H, Burgering BM.

J Biol Chem. 2013 Jul 26;288(30):21729-41. doi: 10.1074/jbc.M113.463885. Epub 2013 Jun 14. Erratum in: J Biol Chem. 2016 Jan 15;291(3):1200.

13.

Redox-dependent control of FOXO/DAF-16 by transportin-1.

Putker M, Madl T, Vos HR, de Ruiter H, Visscher M, van den Berg MC, Kaplan M, Korswagen HC, Boelens R, Vermeulen M, Burgering BM, Dansen TB.

Mol Cell. 2013 Feb 21;49(4):730-42. doi: 10.1016/j.molcel.2012.12.014. Epub 2013 Jan 17.

14.

Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy.

van der Vos KE, Eliasson P, Proikas-Cezanne T, Vervoort SJ, van Boxtel R, Putker M, van Zutphen IJ, Mauthe M, Zellmer S, Pals C, Verhagen LP, Groot Koerkamp MJ, Braat AK, Dansen TB, Holstege FC, Gebhardt R, Burgering BM, Coffer PJ.

Nat Cell Biol. 2012 Aug;14(8):829-37. doi: 10.1038/ncb2536. Epub 2012 Jul 22.

PMID:
22820375
15.

Forkhead Box O transcription factors: key players in redox signaling.

Dansen TB.

Antioxid Redox Signal. 2011 Feb 15;14(4):559-61. doi: 10.1089/ars.2010.3778. Epub 2010 Dec 18.

PMID:
21083421
16.

Activation of forkhead box O transcription factors by oncogenic BRAF promotes p21cip1-dependent senescence.

de Keizer PL, Packer LM, Szypowska AA, Riedl-Polderman PE, van den Broek NJ, de Bruin A, Dansen TB, Marais R, Brenkman AB, Burgering BM.

Cancer Res. 2010 Nov 1;70(21):8526-36. doi: 10.1158/0008-5472.CAN-10-1563. Epub 2010 Oct 19.

17.

Release of Mps1 from kinetochores is crucial for timely anaphase onset.

Jelluma N, Dansen TB, Sliedrecht T, Kwiatkowski NP, Kops GJ.

J Cell Biol. 2010 Oct 18;191(2):281-90. doi: 10.1083/jcb.201003038. Epub 2010 Oct 11.

18.

Forkhead box o as a sensor, mediator, and regulator of redox signaling.

de Keizer PL, Burgering BM, Dansen TB.

Antioxid Redox Signal. 2011 Mar 15;14(6):1093-106. doi: 10.1089/ars.2010.3403. Epub 2010 Sep 20. Review.

PMID:
20626320
19.

Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity.

Dansen TB, Smits LM, van Triest MH, de Keizer PL, van Leenen D, Koerkamp MG, Szypowska A, Meppelink A, Brenkman AB, Yodoi J, Holstege FC, Burgering BM.

Nat Chem Biol. 2009 Sep;5(9):664-72. doi: 10.1038/nchembio.194. Epub 2009 Aug 2.

PMID:
19648934
20.

Unravelling the tumor-suppressive functions of FOXO proteins.

Dansen TB, Burgering BM.

Trends Cell Biol. 2008 Sep;18(9):421-9. doi: 10.1016/j.tcb.2008.07.004. Epub 2008 Aug 18. Review.

PMID:
18715783
21.

Malignant mesothelioma cells are rapidly sensitized to TRAIL-induced apoptosis by low-dose anisomycin via Bim.

Abayasiriwardana KS, Barbone D, Kim KU, Vivo C, Lee KK, Dansen TB, Hunt AE, Evan GI, Broaddus VC.

Mol Cancer Ther. 2007 Oct;6(10):2766-76.

22.

Bcl-xL gain of function and p19 ARF loss of function cooperate oncogenically with Myc in vivo by distinct mechanisms.

Finch A, Prescott J, Shchors K, Hunt A, Soucek L, Dansen TB, Swigart LB, Evan GI.

Cancer Cell. 2006 Aug;10(2):113-20.

23.

Glucose withdrawal induces oxidative stress followed by apoptosis in glioblastoma cells but not in normal human astrocytes.

Jelluma N, Yang X, Stokoe D, Evan GI, Dansen TB, Haas-Kogan DA.

Mol Cancer Res. 2006 May;4(5):319-30.

24.

Radiation-induced caspase-8 mediates p53-independent apoptosis in glioma cells.

Afshar G, Jelluma N, Yang X, Basila D, Arvold ND, Karlsson A, Yount GL, Dansen TB, Koller E, Haas-Kogan DA.

Cancer Res. 2006 Apr 15;66(8):4223-32.

25.

Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo.

Dansen TB, Whitfield J, Rostker F, Brown-Swigart L, Evan GI.

J Biol Chem. 2006 Apr 21;281(16):10890-5. Epub 2006 Feb 7.

26.

Bid mediates apoptotic synergy between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and DNA damage.

Broaddus VC, Dansen TB, Abayasiriwardana KS, Wilson SM, Finch AJ, Swigart LB, Hunt AE, Evan GI.

J Biol Chem. 2005 Apr 1;280(13):12486-93. Epub 2004 Dec 22.

27.

The peroxisomal lumen in Saccharomyces cerevisiae is alkaline.

van Roermund CW, de Jong M, IJlst L, van Marle J, Dansen TB, Wanders RJ, Waterham HR.

J Cell Sci. 2004 Aug 15;117(Pt 18):4231-7.

28.

Regulation of sterol carrier protein gene expression by the forkhead transcription factor FOXO3a.

Dansen TB, Kops GJ, Denis S, Jelluma N, Wanders RJ, Bos JL, Burgering BM, Wirtz KW.

J Lipid Res. 2004 Jan;45(1):81-8. Epub 2003 Oct 16.

29.

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress.

Kops GJ, Dansen TB, Polderman PE, Saarloos I, Wirtz KW, Coffer PJ, Huang TT, Bos JL, Medema RH, Burgering BM.

Nature. 2002 Sep 19;419(6904):316-21.

PMID:
12239572
30.

The peroxisome in oxidative stress.

Dansen TB, Wirtz KW.

IUBMB Life. 2001 Apr;51(4):223-30. Review.

31.

Targeted fluorescent probes in peroxisome function.

Dansen TB, Pap EHW, Wanders RJ, Wirtz KW.

Histochem J. 2001 Feb;33(2):65-9. Review.

PMID:
11432641
32.

Peptide-based targeting of fluorophores to organelles in living cells.

Pap EH, Dansen TB, van Summeren R, Wirtz KW.

Exp Cell Res. 2001 May 1;265(2):288-93.

PMID:
11302694
33.

Peptide-based targeting of fluorophores to peroxisomes in living cells.

Pap EH, Dansen TB, Wirtz KW.

Trends Cell Biol. 2001 Jan;11(1):10-12. Review.

PMID:
11146278
34.

Peroxisomes in human fibroblasts have a basic pH.

Dansen TB, Wirtz KW, Wanders RJ, Pap EH.

Nat Cell Biol. 2000 Jan;2(1):51-3. No abstract available.

PMID:
10620807
35.

Immunological analyses of alkyl-dihydroxyacetone-phosphate synthase in human peroxisomal disorders.

Biermann J, Gootjes J, Humbel BM, Dansen TB, Wanders RJ, van den Bosch H.

Eur J Cell Biol. 1999 May;78(5):339-48.

PMID:
10384985
36.

High-affinity binding of very-long-chain fatty acyl-CoA esters to the peroxisomal non-specific lipid-transfer protein (sterol carrier protein-2).

Dansen TB, Westerman J, Wouters FS, Wanders RJ, van Hoek A, Gadella TW Jr, Wirtz KW.

Biochem J. 1999 Apr 1;339 ( Pt 1):193-9.

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