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Items: 21

1.

High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation-associated versus preneurulation-associated fate patterning.

Tewary M, Dziedzicka D, Ostblom J, Prochazka L, Shakiba N, Heydari T, Aguilar-Hidalgo D, Woodford C, Piccinini E, Becerra-Alonso D, Vickers A, Louis B, Rahman N, Danovi D, Geens M, Watt FM, Zandstra PW.

PLoS Biol. 2019 Oct 21;17(10):e3000081. doi: 10.1371/journal.pbio.3000081. eCollection 2019 Oct.

2.

Correction for Danovi et al., "Amplification of Mdmx (or Mdm4) Directly Contributes to Tumor Formation by Inhibiting p53 Tumor Suppressor Activity".

Danovi D, Meulmeester E, Pasini D, Migliorini D, Capra M, Frenk R, de Graaf P, Francoz S, Gasparini P, Gobbi A, Helin K, Pelicci PG, Jochemsen AG, Marine JC.

Mol Cell Biol. 2019 Jul 16;39(15). pii: e00150-19. doi: 10.1128/MCB.00150-19. Print 2019 Aug 1. No abstract available.

3.

Induction of Neural Crest Stem Cells From Bardet-Biedl Syndrome Patient Derived hiPSCs.

Barrell WB, Griffin JN, Harvey JL; HipSci Consortium, Danovi D, Beales P, Grigoriadis AE, Liu KJ.

Front Mol Neurosci. 2019 Jun 21;12:139. doi: 10.3389/fnmol.2019.00139. eCollection 2019.

4.

Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors.

Vigilante A, Laddach A, Moens N, Meleckyte R, Leha A, Ghahramani A, Culley OJ, Kathuria A, Hurling C, Vickers A, Wiseman E, Tewary M, Zandstra PW; HipSci Consortium, Durbin R, Fraternali F, Stegle O, Birney E, Luscombe NM, Danovi D, Watt FM.

Cell Rep. 2019 Feb 19;26(8):2078-2087.e3. doi: 10.1016/j.celrep.2019.01.094.

5.

Integrated Multiparametric High-Content Profiling of Endothelial Cells.

Wiseman E, Zamuner A, Tang Z, Rogers J, Munir S, Di Silvio L, Danovi D, Veschini L.

SLAS Discov. 2019 Mar;24(3):264-273. doi: 10.1177/2472555218820848. Epub 2019 Jan 25.

6.

Imaging-Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applications.

Ong J, Serra MP, Segal J, Cujba AM, Ng SS, Butler R, Millar V, Hatch S, Zimri S, Koike H, Chan K, Bonham A, Walk M, Voss T, Heaton N, Mitry R, Dhawan A, Ebner D, Danovi D, Nakauchi H, Rashid ST.

Stem Cell Reports. 2018 Mar 13;10(3):693-702. doi: 10.1016/j.stemcr.2018.01.025. Epub 2018 Mar 1.

7.

Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs.

Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, Bala S, Bensaddek D, Casale FP, Culley OJ, Danecek P, Faulconbridge A, Harrison PW, Kathuria A, McCarthy D, McCarthy SA, Meleckyte R, Memari Y, Moens N, Soares F, Mann A, Streeter I, Agu CA, Alderton A, Nelson R, Harper S, Patel M, White A, Patel SR, Clarke L, Halai R, Kirton CM, Kolb-Kokocinski A, Beales P, Birney E, Danovi D, Lamond AI, Ouwehand WH, Vallier L, Watt FM, Durbin R, Stegle O, Gaffney DJ.

Nature. 2017 Jun 29;546(7660):686. doi: 10.1038/nature23012. Epub 2017 Jun 14.

PMID:
28614302
8.

Common genetic variation drives molecular heterogeneity in human iPSCs.

Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, Bala S, Bensaddek D, Casale FP, Culley OJ, Danecek P, Faulconbridge A, Harrison PW, Kathuria A, McCarthy D, McCarthy SA, Meleckyte R, Memari Y, Moens N, Soares F, Mann A, Streeter I, Agu CA, Alderton A, Nelson R, Harper S, Patel M, White A, Patel SR, Clarke L, Halai R, Kirton CM, Kolb-Kokocinski A, Beales P, Birney E, Danovi D, Lamond AI, Ouwehand WH, Vallier L, Watt FM, Durbin R, Stegle O, Gaffney DJ.

Nature. 2017 Jun 15;546(7658):370-375. doi: 10.1038/nature22403. Epub 2017 May 10. Erratum in: Nature. 2017 Jun 29;546(7660):686.

9.

A Novel Automated High-Content Analysis Workflow Capturing Cell Population Dynamics from Induced Pluripotent Stem Cell Live Imaging Data.

Kerz M, Folarin A, Meleckyte R, Watt FM, Dobson RJ, Danovi D.

J Biomol Screen. 2016 Oct;21(9):887-96. doi: 10.1177/1087057116652064. Epub 2016 Jun 2.

10.

A high-content platform to characterise human induced pluripotent stem cell lines.

Leha A, Moens N, Meleckyte R, Culley OJ, Gervasio MK, Kerz M, Reimer A, Cain SA, Streeter I, Folarin A, Stegle O, Kielty CM; HipSci Consortium, Durbin R, Watt FM, Danovi D.

Methods. 2016 Mar 1;96:85-96. doi: 10.1016/j.ymeth.2015.11.012. Epub 2015 Nov 25.

11.

Human pluripotent stem cells on artificial microenvironments: a high content perspective.

Viswanathan P, Gaskell T, Moens N, Culley OJ, Hansen D, Gervasio MK, Yeap YJ, Danovi D.

Front Pharmacol. 2014 Jul 2;5:150. doi: 10.3389/fphar.2014.00150. eCollection 2014. Review.

12.

A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.

Danovi D, Folarin A, Gogolok S, Ender C, Elbatsh AM, Engström PG, Stricker SH, Gagrica S, Georgian A, Yu D, U KP, Harvey KJ, Ferretti P, Paddison PJ, Preston JE, Abbott NJ, Bertone P, Smith A, Pollard SM.

PLoS One. 2013 Oct 30;8(10):e77053. doi: 10.1371/journal.pone.0077053. eCollection 2013.

13.

High content screening of defined chemical libraries using normal and glioma-derived neural stem cell lines.

Danovi D, Folarin AA, Baranowski B, Pollard SM.

Methods Enzymol. 2012;506:311-29. doi: 10.1016/B978-0-12-391856-7.00040-8.

PMID:
22341231
14.

A genetic screen for anchorage-independent proliferation in mammalian cells identifies a membrane-bound neuregulin.

Danovi D, Cremona CA, Machado-da-Silva G, Basu S, Noon LA, Parrinello S, Lloyd AC.

PLoS One. 2010 Jul 26;5(7):e11774. doi: 10.1371/journal.pone.0011774.

15.

Imaging-based chemical screens using normal and glioma-derived neural stem cells.

Danovi D, Falk A, Humphreys P, Vickers R, Tinsley J, Smith AG, Pollard SM.

Biochem Soc Trans. 2010 Aug;38(4):1067-71. doi: 10.1042/BST0381067. Review.

PMID:
20659005
16.

Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens.

Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, Russell R, Bayani J, Head R, Lee M, Bernstein M, Squire JA, Smith A, Dirks P.

Cell Stem Cell. 2009 Jun 5;4(6):568-80. doi: 10.1016/j.stem.2009.03.014.

17.

Myc represses transcription through recruitment of DNA methyltransferase corepressor.

Brenner C, Deplus R, Didelot C, Loriot A, Viré E, De Smet C, Gutierrez A, Danovi D, Bernard D, Boon T, Pelicci PG, Amati B, Kouzarides T, de Launoit Y, Di Croce L, Fuks F.

EMBO J. 2005 Jan 26;24(2):336-46. Epub 2004 Dec 16.

18.

Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity.

Danovi D, Meulmeester E, Pasini D, Migliorini D, Capra M, Frenk R, de Graaf P, Francoz S, Gasparini P, Gobbi A, Helin K, Pelicci PG, Jochemsen AG, Marine JC.

Mol Cell Biol. 2004 Jul;24(13):5835-43. Erratum in: Mol Cell Biol. 2019 Jul 16;39(15):.

19.

Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development.

Migliorini D, Lazzerini Denchi E, Danovi D, Jochemsen A, Capillo M, Gobbi A, Helin K, Pelicci PG, Marine JC.

Mol Cell Biol. 2002 Aug;22(15):5527-38.

20.

Nucleophosmin regulates the stability and transcriptional activity of p53.

Colombo E, Marine JC, Danovi D, Falini B, Pelicci PG.

Nat Cell Biol. 2002 Jul;4(7):529-33.

PMID:
12080348
21.

Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation.

Migliorini D, Danovi D, Colombo E, Carbone R, Pelicci PG, Marine JC.

J Biol Chem. 2002 Mar 1;277(9):7318-23. Epub 2001 Dec 13.

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