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Items: 27

1.

The C-Terminal Region of Bacillus subtilis SwrA Is Required for Activity and Adaptor-Dependent LonA Proteolysis.

Hughes AC, Subramanian S, Dann CE 3rd, Kearns DB.

J Bacteriol. 2018 Feb 23;200(6). pii: e00659-17. doi: 10.1128/JB.00659-17. Print 2018 Mar 15.

2.

MotI (DgrA) acts as a molecular clutch on the flagellar stator protein MotA in Bacillus subtilis.

Subramanian S, Gao X, Dann CE 3rd, Kearns DB.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):13537-13542. doi: 10.1073/pnas.1716231114. Epub 2017 Dec 1.

3.

Correction to Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.

Deis SM, Doshi A, Hou Z, Matherly LH, Gangjee A, Dann CE 3rd.

Biochemistry. 2017 Feb 21;56(7):1025. doi: 10.1021/acs.biochem.7b00092. Epub 2017 Feb 10. No abstract available.

PMID:
28186409
4.

Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.

Golani LK, Wallace-Povirk A, Deis SM, Wong J, Ke J, Gu X, Raghavan S, Wilson MR, Li X, Polin L, de Waal PW, White K, Kushner J, O'Connor C, Hou Z, Xu HE, Melcher K, Dann CE 3rd, Matherly LH, Gangjee A.

J Med Chem. 2016 Sep 8;59(17):7856-76. doi: 10.1021/acs.jmedchem.6b00594. Epub 2016 Aug 26.

5.

Structural and Enzymatic Analysis of Tumor-Targeted Antifolates That Inhibit Glycinamide Ribonucleotide Formyltransferase.

Deis SM, Doshi A, Hou Z, Matherly LH, Gangjee A, Dann CE 3rd.

Biochemistry. 2016 Aug 16;55(32):4574-82. doi: 10.1021/acs.biochem.6b00412. Epub 2016 Aug 3. Erratum in: Biochemistry. 2017 Feb 21;56(7):1025.

6.

6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor α and the Proton-Coupled Folate Transporter in Human Tumors.

Wang L, Wallace A, Raghavan S, Deis SM, Wilson MR, Yang S, Polin L, White K, Kushner J, Orr S, George C, O'Connor C, Hou Z, Mitchell-Ryan S, Dann CE 3rd, Matherly LH, Gangjee A.

J Med Chem. 2015 Sep 10;58(17):6938-59. doi: 10.1021/acs.jmedchem.5b00801. Epub 2015 Aug 28.

7.

Engineering of Bacillus subtilis strains to allow rapid characterization of heterologous diguanylate cyclases and phosphodiesterases.

Gao X, Dong X, Subramanian S, Matthews PM, Cooper CA, Kearns DB, Dann CE 3rd.

Appl Environ Microbiol. 2014 Oct;80(19):6167-74. doi: 10.1128/AEM.01638-14. Epub 2014 Aug 1.

8.

Cu(I)-mediated allosteric switching in a copper-sensing operon repressor (CsoR).

Chang FM, Coyne HJ, Cubillas C, Vinuesa P, Fang X, Ma Z, Ma D, Helmann JD, García-de los Santos A, Wang YX, Dann CE 3rd, Giedroc DP.

J Biol Chem. 2014 Jul 4;289(27):19204-17. doi: 10.1074/jbc.M114.556704. Epub 2014 May 15.

9.

Redox and light control the heme-sensing activity of AppA.

Yin L, Dragnea V, Feldman G, Hammad LA, Karty JA, Dann CE 3rd, Bauer CE.

MBio. 2013 Aug 27;4(5):e00563-13. doi: 10.1128/mBio.00563-13.

10.

Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.

Wibowo AS, Singh M, Reeder KM, Carter JJ, Kovach AR, Meng W, Ratnam M, Zhang F, Dann CE 3rd.

Proc Natl Acad Sci U S A. 2013 Sep 17;110(38):15180-8. doi: 10.1073/pnas.1308827110. Epub 2013 Aug 9.

11.

Functional characterization of core components of the Bacillus subtilis cyclic-di-GMP signaling pathway.

Gao X, Mukherjee S, Matthews PM, Hammad LA, Kearns DB, Dann CE 3rd.

J Bacteriol. 2013 Nov;195(21):4782-92. doi: 10.1128/JB.00373-13. Epub 2013 Jul 26.

12.

A new structural paradigm in copper resistance in Streptococcus pneumoniae.

Fu Y, Tsui HC, Bruce KE, Sham LT, Higgins KA, Lisher JP, Kazmierczak KM, Maroney MJ, Dann CE 3rd, Winkler ME, Giedroc DP.

Nat Chem Biol. 2013 Mar;9(3):177-83. doi: 10.1038/nchembio.1168. Epub 2013 Jan 27.

13.

Allosteric inhibition of a zinc-sensing transcriptional repressor: insights into the arsenic repressor (ArsR) family.

Campanello GC, Ma Z, Grossoehme NE, Guerra AJ, Ward BP, Dimarchi RD, Ye Y, Dann CE 3rd, Giedroc DP.

J Mol Biol. 2013 Apr 12;425(7):1143-57. doi: 10.1016/j.jmb.2013.01.018. Epub 2013 Jan 23.

14.

Oxidative lipid modification of nicastrin enhances amyloidogenic γ-secretase activity in Alzheimer's disease.

Gwon AR, Park JS, Arumugam TV, Kwon YK, Chan SL, Kim SH, Baik SH, Yang S, Yun YK, Choi Y, Kim S, Tang SC, Hyun DH, Cheng A, Dann CE 3rd, Bernier M, Lee J, Markesbery WR, Mattson MP, Jo DG.

Aging Cell. 2012 Aug;11(4):559-68. doi: 10.1111/j.1474-9726.2012.00817.x. Epub 2012 Apr 9.

15.

Crystal structure of the zinc-dependent MarR family transcriptional regulator AdcR in the Zn(II)-bound state.

Guerra AJ, Dann CE 3rd, Giedroc DP.

J Am Chem Soc. 2011 Dec 14;133(49):19614-7. doi: 10.1021/ja2080532. Epub 2011 Nov 21.

16.

RNA structure: Riboswitch strikes a chord.

Dann CE 3rd.

Nat Chem Biol. 2011 Sep 19;7(10):660-1. doi: 10.1038/nchembio.672. No abstract available.

PMID:
21931314
17.

Conformational changes in the hepatitis B virus core protein are consistent with a role for allostery in virus assembly.

Packianathan C, Katen SP, Dann CE 3rd, Zlotnick A.

J Virol. 2010 Feb;84(3):1607-15. doi: 10.1128/JVI.02033-09. Epub 2009 Nov 25.

18.

Coronavirus N protein N-terminal domain (NTD) specifically binds the transcriptional regulatory sequence (TRS) and melts TRS-cTRS RNA duplexes.

Grossoehme NE, Li L, Keane SC, Liu P, Dann CE 3rd, Leibowitz JL, Giedroc DP.

J Mol Biol. 2009 Dec 4;394(3):544-57. doi: 10.1016/j.jmb.2009.09.040. Epub 2009 Sep 24.

19.

Structure and mechanism of a metal-sensing regulatory RNA.

Dann CE 3rd, Wakeman CA, Sieling CL, Baker SC, Irnov I, Winkler WC.

Cell. 2007 Sep 7;130(5):878-92.

20.

Structural features of metabolite-sensing riboswitches.

Wakeman CA, Winkler WC, Dann CE 3rd.

Trends Biochem Sci. 2007 Sep;32(9):415-24. Epub 2007 Aug 30. Review.

21.

RNA allostery glimpsed.

Winkler WC, Dann CE 3rd.

Nat Struct Mol Biol. 2006 Jul;13(7):569-71. No abstract available.

PMID:
16826230
22.

Dioxygenases as O2-dependent regulators of the hypoxic response pathway.

Dann CE 3rd, Bruick RK.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):639-47. Epub 2005 Aug 26. Review.

PMID:
16140259
23.

Nicastrin functions as a gamma-secretase-substrate receptor.

Shah S, Lee SF, Tabuchi K, Hao YH, Yu C, LaPlant Q, Ball H, Dann CE 3rd, Südhof T, Yu G.

Cell. 2005 Aug 12;122(3):435-47.

24.

Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A.

Hamaoka BY, Dann CE 3rd, Geisbrecht BV, Leahy DJ.

Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11673-8. Epub 2004 Aug 2.

25.

Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway.

Dann CE 3rd, Bruick RK, Deisenhofer J.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15351-6. Epub 2002 Nov 13.

26.

Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains.

Dann CE, Hsieh JC, Rattner A, Sharma D, Nathans J, Leahy DJ.

Nature. 2001 Jul 5;412(6842):86-90.

PMID:
11452312
27.

A mammalian expression vector for expression and purification of secreted proteins for structural studies.

Leahy DJ, Dann CE 3rd, Longo P, Perman B, Ramyar KX.

Protein Expr Purif. 2000 Dec;20(3):500-6.

PMID:
11087690

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