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Items: 1 to 50 of 88

1.

Randomized phase 1 healthy volunteer study of UTTR1147A (IL-22Fc), a potential therapy for epithelial injury.

Rothenberg ME, Wang Y, Lekkerkerker A, Danilenko DM, Maciuca R, Erickson R, Herman A, Stefanich E, Lu TT.

Clin Pharmacol Ther. 2018 Jun 28. doi: 10.1002/cpt.1164. [Epub ahead of print]

PMID:
29952004
2.

Pre-clinical and translational pharmacology of a human interleukin-22 IgG fusion protein for potential treatment of infectious or inflammatory diseases.

Stefanich EG, Rae J, Sukumaran S, Lutman J, Lekkerkerker A, Ouyang W, Wang X, Lee D, Danilenko DM, Diehl L, Loyet KM, Herman A.

Biochem Pharmacol. 2018 Jun;152:224-235. doi: 10.1016/j.bcp.2018.03.031. Epub 2018 Mar 31.

PMID:
29608910
3.

Review article: nonclinical and clinical pharmacology, pharmacokinetics and pharmacodynamics of etrolizumab, an anti-β7 integrin therapy for inflammatory bowel disease.

Tang MT, Keir ME, Erickson R, Stefanich EG, Fuh FK, Ramirez-Montagut T, McBride JM, Danilenko DM.

Aliment Pharmacol Ther. 2018 Jun;47(11):1440-1452. doi: 10.1111/apt.14631. Epub 2018 Mar 30. Review.

4.

Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing.

Li J, Stagg NJ, Johnston J, Harris MJ, Menzies SA, DiCara D, Clark V, Hristopoulos M, Cook R, Slaga D, Nakamura R, McCarty L, Sukumaran S, Luis E, Ye Z, Wu TD, Sumiyoshi T, Danilenko D, Lee GY, Totpal K, Ellerman D, Hötzel I, James JR, Junttila TT.

Cancer Cell. 2017 Mar 13;31(3):383-395. doi: 10.1016/j.ccell.2017.02.001. Epub 2017 Mar 2.

5.

IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice.

Kolumam G, Wu X, Lee WP, Hackney JA, Zavala-Solorio J, Gandham V, Danilenko DM, Arora P, Wang X, Ouyang W.

PLoS One. 2017 Jan 26;12(1):e0170639. doi: 10.1371/journal.pone.0170639. eCollection 2017.

6.

Anti-CD22 and anti-CD79b antibody-drug conjugates preferentially target proliferating B cells.

Fuh FK, Looney C, Li D, Poon KA, Dere RC, Danilenko DM, McBride J, Reed C, Chung S, Zheng B, Mathews WR, Polson A, Prabhu S, Williams M.

Br J Pharmacol. 2017 Apr;174(8):628-640. doi: 10.1111/bph.13697. Epub 2017 Mar 6.

7.

Preclinical Safety Profile of a Depleting Antibody against CRTh2 for Asthma: Well Tolerated Despite Unexpected CRTh2 Expression on Vascular Pericytes in the Central Nervous System and Gastric Mucosa.

Rajapaksa KS, Huang T, Sharma N, Liu S, Solon M, Reyes A, Paul S, Yee A, Tao J, Chalasani S, Bien-Ly N, Barck K, Carano RA, Wang J, Rangell L, Bremer M, Danilenko DM, Katavolos P, Hotzel I, Reif K, Austin CD.

Toxicol Sci. 2016 Jul;152(1):72-84. doi: 10.1093/toxsci/kfw067. Epub 2016 Apr 21.

PMID:
27103662
8.

Nonselective inhibition of the epigenetic transcriptional regulator BET induces marked lymphoid and hematopoietic toxicity in mice.

Lee DU, Katavolos P, Palanisamy G, Katewa A, Sioson C, Corpuz J, Pang J, DeMent K, Choo E, Ghilardi N, Diaz D, Danilenko DM.

Toxicol Appl Pharmacol. 2016 Jun 1;300:47-54. doi: 10.1016/j.taap.2016.03.013. Epub 2016 Apr 11.

PMID:
27078884
9.

[THE COMPARATIVE ANALYSIS OF EFFECTIVENESS OF QUICK TESTS IN DIAGNOSTIC OF INFLUENZA AND RESPIRATORY SYNCYTIAL VIRAL INFECTION IN CHILDREN].

Petrova ER, Sukhovetskaia VP, Pisareva MM, Maiorova VG, Sverlova MV, Danilenko DM, Petrova PA, Krivitskaia VZ, Sominina AA.

Klin Lab Diagn. 2015 Nov;60(11):44-9. Russian.

PMID:
26999865
10.

An Overview of the Pathogenesis of Immune-mediated Skin Injury.

Danilenko DM.

Toxicol Pathol. 2016 Jun;44(4):536-44. doi: 10.1177/0192623316632939. Epub 2016 Mar 18. Review.

PMID:
26992887
11.

Rapid spread of influenza A(H1N1)pdm09 viruses with a new set of specific mutations in the internal genes in the beginning of 2015/2016 epidemic season in Moscow and Saint Petersburg (Russian Federation).

Komissarov A, Fadeev A, Sergeeva M, Petrov S, Sintsova K, Egorova A, Pisareva M, Buzitskaya Z, Musaeva T, Danilenko D, Konovalova N, Petrova P, Stolyarov K, Smorodintseva E, Burtseva E, Krasnoslobodtsev K, Kirillova E, Karpova L, Eropkin M, Sominina A, Grudinin M.

Influenza Other Respir Viruses. 2016 Jul;10(4):247-53. doi: 10.1111/irv.12389. Epub 2016 May 27.

12.

In Vitro Skin Models and Their Predictability in Defining Normal and Disease Biology, Pharmacology, and Toxicity.

Danilenko DM, Phillips GD, Diaz D.

Toxicol Pathol. 2016 Jun;44(4):555-63. doi: 10.1177/0192623316632074. Epub 2016 Mar 2.

PMID:
26940714
13.

Therapeutic Antibody-Induced Vascular Toxicity Due to Off-Target Activation of Nitric Oxide in Cynomolgus Monkeys.

Pai R, Ma N, Connor AV, Danilenko DM, Tarrant JM, Salvail D, Wong L, Hartley DP, Misner D, Stefanich E, Wu Y, Chen Y, Wang H, Dambach DM.

Toxicol Sci. 2016 Jun;151(2):245-60. doi: 10.1093/toxsci/kfw037. Epub 2016 Feb 25.

PMID:
26917699
14.
15.

[Comparative study of MDCK and CaCo-2 cell lines for influenza virus isolation].

Danilenko DM, Smirnova TD, Gudkova TM, Prokopets AV, Bil'danova ER, Kadyrova RA, Slita AV, Eropkin MIu.

Vopr Virusol. 2014 Mar-Apr;59(2):40-5. Russian.

PMID:
25069285
16.

A brief overview of the 32nd Annual STP Symposium on the Toxicologic Pathology of the Digestive Tract and Pancreas.

Danilenko DM, Nambiar PR, Cesta MF.

Vet Pathol. 2014 Mar;51(2):541-4. doi: 10.1177/0300985813519133. Epub 2014 Jan 17. No abstract available.

PMID:
24442576
17.

A brief overview of the 32nd Annual STP Symposium on the Toxicologic Pathology of the Digestive Tract and Pancreas.

Danilenko DM, Nambiar PR, Cesta MF.

Toxicol Pathol. 2014 Jan;42(1):45-8. doi: 10.1177/0192623313502402. Epub 2013 Sep 2. No abstract available.

PMID:
24002990
18.

[Role of cellular cytoskeleton in influenza A infectious cycle].

Smirnova TD, Danilenko DM, Slita AV.

Tsitologiia. 2013;55(2):92-100. Review. Russian.

PMID:
23718071
19.

DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma.

Li D, Poon KA, Yu SF, Dere R, Go M, Lau J, Zheng B, Elkins K, Danilenko D, Kozak KR, Chan P, Chuh J, Shi X, Nazzal D, Fuh F, McBride J, Ramakrishnan V, de Tute R, Rawstron A, Jack AS, Deng R, Chu YW, Dornan D, Williams M, Ho W, Ebens A, Prabhu S, Polson AG.

Mol Cancer Ther. 2013 Jul;12(7):1255-65. doi: 10.1158/1535-7163.MCT-12-1173. Epub 2013 Apr 18.

20.

[Evolutionary variability of influenza B viruses in Russian Federation in 2005-2012].

Lobova TG, Prokopets AV, Komissarov AB, Danilenko DM, Paiankova AA, Sukhovetskaia VF, Gudkova TM, Grigor'eva VA, Grudinin MP, Eropkin MIu.

Vopr Virusol. 2012 Nov-Dec;57(6):22-6. Russian.

PMID:
23477250
21.

[Development of influenza surveillance in Russia in the system of the WHO national influenza center].

Sominina AA, Grudinin MP, Eropkin MIu, Smorodintseva EA, Pisareva MM, Konissarov AB, Konovalova NI, Danilenko DM, Gudkova TM, Kiselev IO.

Vopr Virusol. 2012 Nov-Dec;57(6):17-21. Russian.

PMID:
23477249
22.

Polar solvents decrease the viscosity of high concentration IgG1 solutions through hydrophobic solvation and interaction: formulation and biocompatibility considerations.

Kamerzell TJ, Pace AL, Li M, Danilenko DM, McDowell M, Gokarn YR, Wang YJ.

J Pharm Sci. 2013 Apr;102(4):1182-93. doi: 10.1002/jps.23453. Epub 2013 Jan 28.

PMID:
23359242
23.

INFLUENZA SURVEILLANCE IN RUSSIA BASED ON EPIDEMIOLOGICAL AND LABORATORY DATA FOR THE PERIOD FROM 2005 TO 2012.

Anna S, Burtseva E, Eropkin M, Karpova L, Zarubaev V, Smorodintseva E, Konovalova N, Danilenko D, Prokopetz A, Grudinin M, Pisareva M, Anfimov P, Stolyarov K, Kiselev O, Shevchenko E, Ivanova V, Trushakova S, Breslav N, Lvov D, Klimov A, Moen A, Cox N.

Am J Infect Dis. 2013;9(3):77-93.

24.

Proliferative and non-proliferative lesions of the rat and mouse integument.

Mecklenburg L, Kusewitt D, Kolly C, Treumann S, Adams ET, Diegel K, Yamate J, Kaufmann W, Müller S, Danilenko D, Bradley A.

J Toxicol Pathol. 2013;26(3 Suppl):27S-57S. doi: 10.1293/tox.26.27S. Review.

25.

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis.

Rutgeerts PJ, Fedorak RN, Hommes DW, Sturm A, Baumgart DC, Bressler B, Schreiber S, Mansfield JC, Williams M, Tang M, Visich J, Wei X, Keir M, Luca D, Danilenko D, Egen J, O'Byrne S.

Gut. 2013 Aug;62(8):1122-30. doi: 10.1136/gutjnl-2011-301769. Epub 2012 Jun 20.

26.

Minipig as a potential translatable model for monoclonal antibody pharmacokinetics after intravenous and subcutaneous administration.

Zheng Y, Tesar DB, Benincosa L, Birnböck H, Boswell CA, Bumbaca D, Cowan KJ, Danilenko DM, Daugherty AL, Fielder PJ, Grimm HP, Joshi A, Justies N, Kolaitis G, Lewin-Koh N, Li J, McVay S, O'Mahony J, Otteneder M, Pantze M, Putnam WS, Qiu ZJ, Ruppel J, Singer T, Stauch O, Theil FP, Visich J, Yang J, Ying Y, Khawli LA, Richter WF.

MAbs. 2012 Mar-Apr;4(2):243-55. doi: 10.4161/mabs.4.2.19387. Epub 2012 Mar 1.

27.
28.

The yin and yang of immunomodulatory biologics: assessing the delicate balance between benefit and risk.

Danilenko DM, Wang H.

Toxicol Pathol. 2012;40(2):272-87. doi: 10.1177/0192623311430237. Epub 2012 Jan 5. Review.

PMID:
22222884
29.

A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.

Schaefer G, Haber L, Crocker LM, Shia S, Shao L, Dowbenko D, Totpal K, Wong A, Lee CV, Stawicki S, Clark R, Fields C, Lewis Phillips GD, Prell RA, Danilenko DM, Franke Y, Stephan JP, Hwang J, Wu Y, Bostrom J, Sliwkowski MX, Fuh G, Eigenbrot C.

Cancer Cell. 2011 Oct 18;20(4):472-86. doi: 10.1016/j.ccr.2011.09.003.

30.

[Analysis of pandemic influenza in Russia as a part of the global process based on data of an influenza monitoring reference center].

Solomina AA, Grudinin MP, Eropkin MIu, Karpova LS, Pisareva MM, Komissarov AB, Konovalova NI, Gudkova TM, Danilenko DM, Smorodintseva EA, Voĭtsekhovskaia EM, Kiselev OI.

Zh Mikrobiol Epidemiol Immunobiol. 2011 May-Jun;(3):20-6. Russian.

PMID:
21809641
31.

[Pandemic influenza 2009 in Russia. Characteristics of the isolation and biological properties of viruses].

Danilenko DM, Konovalova NI, Eropkin MY, Gudkova TM, Grigoryeva VA, Ivanova AV, Shchekanova SM, Smirnova TD, Kiselev OI.

Vopr Virusol. 2011 Mar-Apr;56(2):4-9. Russian.

PMID:
21545032
32.

[Comparative characteristics of porphyrins metabolism in chronic viral diseases of the liver].

Krivosheev AB, Kondratova MA, Krivosheev BN, Morozov DV, Danilenko DB.

Ter Arkh. 2011;83(2):40-7. Russian.

PMID:
21516848
33.

[The 2009 pandemic influenza in Russia. I. Diagnosis and molecular biological characteristics of the virus].

Kiselev OI, Komissarov AB, Stukova MA, Buzitskaia ZhV, Pisareva MM, Elpaeva EA, Danilenko DM, Konovalova NI, Gudkova TM, Grigor'eva VA, Smirnova TS, Slita AV, Romanovskaia-Roman'ko EA, Tsybalova LM, Sominina AA, Eropkin MIu, Grudinin MP.

Vopr Virusol. 2011 Jan-Feb;56(1):17-21. Russian.

PMID:
21427949
34.

A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes.

Stefanich EG, Danilenko DM, Wang H, O'Byrne S, Erickson R, Gelzleichter T, Hiraragi H, Chiu H, Ivelja S, Jeet S, Gadkari S, Hwang O, Fuh F, Looney C, Howell K, Albert V, Balazs M, Refino C, Fong S, Iyer S, Williams M.

Br J Pharmacol. 2011 Apr;162(8):1855-70. doi: 10.1111/j.1476-5381.2011.01205.x.

35.

[Influence of rimantadine, ribavirine and triazavirine on influenza A virus replication in human monolayer and lymphoblastoid cell lines].

Smirnova TD, Danilenko DM, Eropkin MIu, Deeva EG, Kiselev OI.

Antibiot Khimioter. 2011;56(11-12):11-6. Russian.

PMID:
22856151
36.

IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.

Batten M, Ramamoorthi N, Kljavin NM, Ma CS, Cox JH, Dengler HS, Danilenko DM, Caplazi P, Wong M, Fulcher DA, Cook MC, King C, Tangye SG, de Sauvage FJ, Ghilardi N.

J Exp Med. 2010 Dec 20;207(13):2895-906. doi: 10.1084/jem.20100064. Epub 2010 Nov 22.

37.

Actin-bundling protein L-plastin regulates T cell activation.

Wang C, Morley SC, Donermeyer D, Peng I, Lee WP, Devoss J, Danilenko DM, Lin Z, Zhang J, Zhou J, Allen PM, Brown EJ.

J Immunol. 2010 Dec 15;185(12):7487-97. doi: 10.4049/jimmunol.1001424. Epub 2010 Nov 12. Erratum in: J Immunol. 2011 Aug 1;187(3):1514.

38.

[Etiological characteristics of the influenza epidemics of 2006-2009 in the Russian Federation (according to the data of the Research Institute of Influenza, North-Western Branch, Russian Academy of Medical Sciences)].

Konovalova NI, Eropkin MIu, Gudkova TM, Grigor'eva VA, Danilenko DM, Ivanova AV, Smirnova TS, Lobova TG, Shchekanova SM.

Vopr Virusol. 2010 Jul-Aug;55(4):9-16. Russian.

PMID:
20886706
39.

B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity.

Weber MS, Prod'homme T, Patarroyo JC, Molnarfi N, Karnezis T, Lehmann-Horn K, Danilenko DM, Eastham-Anderson J, Slavin AJ, Linington C, Bernard CC, Martin F, Zamvil SS.

Ann Neurol. 2010 Sep;68(3):369-83. doi: 10.1002/ana.22081.

40.

[Study of the antiviral activity of Russian anti-influenza agents in cell culture and animal models].

Leneva IA, Fediakina IT, Eropkin MIu, Gudova NV, Romanovskaia AA, Danilenko DM, Vinogradova SM, Lepeshkin AIu, Shestopalov AM.

Vopr Virusol. 2010 May-Jun;55(3):19-27. Russian.

PMID:
20608077
41.

IL-17RC is required for IL-17A- and IL-17F-dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis.

Hu Y, Ota N, Peng I, Refino CJ, Danilenko DM, Caplazi P, Ouyang W.

J Immunol. 2010 Apr 15;184(8):4307-16. doi: 10.4049/jimmunol.0903614. Epub 2010 Mar 15.

42.

Genetic deletion of JAM-C reveals a role in myeloid progenitor generation.

Praetor A, McBride JM, Chiu H, Rangell L, Cabote L, Lee WP, Cupp J, Danilenko DM, Fong S.

Blood. 2009 Feb 26;113(9):1919-28. doi: 10.1182/blood-2008-06-159574. Epub 2008 Dec 24.

43.

The serine protease marapsin is expressed in stratified squamous epithelia and is up-regulated in the hyperproliferative epidermis of psoriasis and regenerating wounds.

Li W, Danilenko DM, Bunting S, Ganesan R, Sa S, Ferrando R, Wu TD, Kolumam GA, Ouyang W, Kirchhofer D.

J Biol Chem. 2009 Jan 2;284(1):218-28. doi: 10.1074/jbc.M806267200. Epub 2008 Oct 23.

44.

Evidence for an asialoglycoprotein receptor on nonparenchymal cells for O-linked glycoproteins.

Stefanich EG, Ren S, Danilenko DM, Lim A, Song A, Iyer S, Fielder PJ.

J Pharmacol Exp Ther. 2008 Nov;327(2):308-15. doi: 10.1124/jpet.108.142232. Epub 2008 Aug 26.

45.

Review paper: preclinical models of psoriasis.

Danilenko DM.

Vet Pathol. 2008 Jul;45(4):563-75. doi: 10.1354/vp.45-4-563. Review.

PMID:
18587106
46.

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens.

Zheng Y, Valdez PA, Danilenko DM, Hu Y, Sa SM, Gong Q, Abbas AR, Modrusan Z, Ghilardi N, de Sauvage FJ, Ouyang W.

Nat Med. 2008 Mar;14(3):282-9. doi: 10.1038/nm1720. Epub 2008 Feb 10.

PMID:
18264109
47.

Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade.

Lin WY, Gong Q, Seshasayee D, Lin Z, Ou Q, Ye S, Suto E, Shu J, Lee WP, Lee CW, Fuh G, Leabman M, Iyer S, Howell K, Gelzleichter T, Beyer J, Danilenko D, Yeh S, DeForge LE, Ebens A, Thompson JS, Ambrose C, Balazs M, Starovasnik MA, Martin F.

Blood. 2007 Dec 1;110(12):3959-67. Epub 2007 Aug 8.

48.

The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.

Sa SM, Valdez PA, Wu J, Jung K, Zhong F, Hall L, Kasman I, Winer J, Modrusan Z, Danilenko DM, Ouyang W.

J Immunol. 2007 Feb 15;178(4):2229-40. Erratum in: J Immunol. 2007 Jun 1;178(11):7487.

49.

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis.

Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham-Anderson J, Wu J, Ouyang W.

Nature. 2007 Feb 8;445(7128):648-51. Epub 2006 Dec 24.

PMID:
17187052
50.

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells.

Batten M, Li J, Yi S, Kljavin NM, Danilenko DM, Lucas S, Lee J, de Sauvage FJ, Ghilardi N.

Nat Immunol. 2006 Sep;7(9):929-36. Epub 2006 Aug 13.

PMID:
16906167

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