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The cost of long catalytic loops in folding and stability of the ALS-associated protein SOD1.

Yang F, Wang H, Logan DT, Mu X, Danielsson J, Oliveberg M.

J Am Chem Soc. 2018 Oct 25. doi: 10.1021/jacs.8b08141. [Epub ahead of print]


Formal Synthesis of ent-Cephalotaxine Using a One-Pot Parham-Aldol Sequence.

Siitonen JH, Yu L, Danielsson J, Di Gregorio G, Somfai P.

J Org Chem. 2018 Sep 21;83(18):11318-11322. doi: 10.1021/acs.joc.8b01540. Epub 2018 Jul 31.


Functional comparison of anoctamin 1 antagonists on human uterine smooth muscle contractility and excitability.

Hyuga S, Danielsson J, Vink J, Fu XW, Wapner R, Gallos G.

J Smooth Muscle Res. 2018;54(0):28-42. doi: 10.1540/jsmr.54.28.


Gastrostomi hos barn – följ nationella riktlinjer.

Danielsson J, Rutqvist J, Göthberg G, Arnjörnsson E.

Lakartidningen. 2018 May 4;115. pii: E6U6. Swedish. No abstract available.

Free Article

The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium.

Matsuyama N, Shibata S, Matoba A, Kudo TA, Danielsson J, Kohjitani A, Masaki E, Emala CW, Mizuta K.

Respir Res. 2018 Apr 2;19(1):53. doi: 10.1186/s12931-018-0757-4.


Anoctamin Channels in Human Myometrium: A Novel Target for Tocolysis.

Danielsson J, Vink J, Hyuga S, Fu XW, Funayama H, Wapner R, Blanks AM, Gallos G.

Reprod Sci. 2018 Nov;25(11):1589-1600. doi: 10.1177/1933719118757683. Epub 2018 Feb 22.


A Stereocontrolled Annulation of the Taccalonolide Epoxy Lactone onto the Molecular Framework of trans-Androsterone.

Danielsson J, Sun DX, Chen XY, Risinger AL, Mooberry SL, Sorensen EJ.

Org Lett. 2017 Sep 15;19(18):4892-4895. doi: 10.1021/acs.orglett.7b02349. Epub 2017 Aug 29.


Physicochemical code for quinary protein interactions in Escherichia coli.

Mu X, Choi S, Lang L, Mowray D, Dokholyan NV, Danielsson J, Oliveberg M.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4556-E4563. doi: 10.1073/pnas.1621227114. Epub 2017 May 23.


GABAA receptor α4-subunit knockout enhances lung inflammation and airway reactivity in a murine asthma model.

Yocum GT, Turner DL, Danielsson J, Barajas MB, Zhang Y, Xu D, Harrison NL, Homanics GE, Farber DL, Emala CW.

Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L406-L415. doi: 10.1152/ajplung.00107.2017. Epub 2017 May 4.


Comparing protein behaviour in vitro and in vivo, what does the data really tell us?

Danielsson J, Oliveberg M.

Curr Opin Struct Biol. 2017 Feb;42:129-135. doi: 10.1016/ Epub 2017 Jan 23. Review.


Impaired Relaxation of Airway Smooth Muscle in Mice Lacking the Actin-Binding Protein Gelsolin.

Mikami M, Zhang Y, Danielsson J, Joell T, Yong HM, Townsend E, Khurana S, An SS, Emala CW.

Am J Respir Cell Mol Biol. 2017 May;56(5):628-636. doi: 10.1165/rcmb.2016-0292OC.


Tricking a Protein To Swap Strands.

Wang H, Lang L, Logan DT, Danielsson J, Oliveberg M.

J Am Chem Soc. 2016 Dec 7;138(48):15571-15579. Epub 2016 Nov 22.


Comorbidities and elevated IL-6 associate with negative outcome in adult-onset asthma.

Ilmarinen P, Tuomisto LE, Niemelä O, Danielsson J, Haanpää J, Kankaanranta T, Kankaanranta H.

Eur Respir J. 2016 Oct;48(4):1052-1062. doi: 10.1183/13993003.02198-2015. Epub 2016 Aug 18.


Membrane-Induced Folding of the Plant Stress Dehydrin Lti30.

Eriksson S, Eremina N, Barth A, Danielsson J, Harryson P.

Plant Physiol. 2016 Jun;171(2):932-43. doi: 10.1104/pp.15.01531. Epub 2016 Apr 26.


Ionic Strength Modulation of the Free Energy Landscape of Aβ40 Peptide Fibril Formation.

Abelein A, Jarvet J, Barth A, Gräslund A, Danielsson J.

J Am Chem Soc. 2016 Jun 1;138(21):6893-902. doi: 10.1021/jacs.6b04511. Epub 2016 May 23.


Airway Epithelial Cell Release of GABA is Regulated by Protein Kinase A.

Danielsson J, Zaidi S, Kim B, Funayama H, Yim PD, Xu D, Worgall TS, Gallos G, Emala CW.

Lung. 2016 Jun;194(3):401-8. doi: 10.1007/s00408-016-9867-2. Epub 2016 Mar 17.


Attenuation of airway smooth muscle contractility via flavonol-mediated inhibition of phospholipase-Cβ.

Brown A, Danielsson J, Townsend EA, Zhang Y, Perez-Zoghbi JF, Emala CW Sr, Gallos G.

Am J Physiol Lung Cell Mol Physiol. 2016 Apr 15;310(8):L747-58. doi: 10.1152/ajplung.00215.2015. Epub 2016 Jan 15.


Thermodynamics of protein destabilization in live cells.

Danielsson J, Mu X, Lang L, Wang H, Binolfi A, Theillet FX, Bekei B, Logan DT, Selenko P, Wennerström H, Oliveberg M.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12402-7. doi: 10.1073/pnas.1511308112. Epub 2015 Sep 21.


SOD1 aggregation in ALS mice shows simplistic test tube behavior.

Lang L, Zetterström P, Brännström T, Marklund SL, Danielsson J, Oliveberg M.

Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9878-83. doi: 10.1073/pnas.1503328112. Epub 2015 Jul 28.


Antagonists of the TMEM16A calcium-activated chloride channel modulate airway smooth muscle tone and intracellular calcium.

Danielsson J, Perez-Zoghbi J, Bernstein K, Barajas MB, Zhang Y, Kumar S, Sharma PK, Gallos G, Emala CW.

Anesthesiology. 2015 Sep;123(3):569-81. doi: 10.1097/ALN.0000000000000769.


Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation.

Abelein A, Gräslund A, Danielsson J.

Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5407-12. doi: 10.1073/pnas.1421961112. Epub 2015 Mar 30.


Structural and kinetic analysis of protein-aggregate strains in vivo using binary epitope mapping.

Bergh J, Zetterström P, Andersen PM, Brännström T, Graffmo KS, Jonsson PA, Lang L, Danielsson J, Oliveberg M, Marklund SL.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4489-94. doi: 10.1073/pnas.1419228112. Epub 2015 Mar 23.


Impacts of common factors of life style on serum liver enzymes.

Danielsson J, Kangastupa P, Laatikainen T, Aalto M, Niemelä O.

World J Gastroenterol. 2014 Sep 7;20(33):11743-52. doi: 10.3748/wjg.v20.i33.11743.


Calcium-activated chloride channels anoctamin 1 and 2 promote murine uterine smooth muscle contractility.

Bernstein K, Vink JY, Fu XW, Wakita H, Danielsson J, Wapner R, Gallos G.

Am J Obstet Gynecol. 2014 Dec;211(6):688.e1-10. doi: 10.1016/j.ajog.2014.06.018. Epub 2014 Jun 11.


Serum soluble urokinase plasminogen activator receptor in alcoholics: relation to liver disease severity, fibrogenesis, and alcohol use.

Tuomi H, Kultti J, Danielsson J, Kangastupa P, Akerman K, Niemelä O.

J Gastroenterol Hepatol. 2014 Dec;29(12):1991-5. doi: 10.1111/jgh.12639.


Chloride channel blockade relaxes airway smooth muscle and potentiates relaxation by β-agonists.

Danielsson J, Yim P, Rinderspacher A, Fu XW, Zhang Y, Landry DW, Emala CW.

Am J Physiol Lung Cell Mol Physiol. 2014 Aug 1;307(3):L273-82. doi: 10.1152/ajplung.00351.2013. Epub 2014 May 30.


The hairpin conformation of the amyloid β peptide is an important structural motif along the aggregation pathway.

Abelein A, Abrahams JP, Danielsson J, Gräslund A, Jarvet J, Luo J, Tiiman A, Wärmländer SK.

J Biol Inorg Chem. 2014 Jun;19(4-5):623-34. doi: 10.1007/s00775-014-1131-8. Epub 2014 Apr 16. Review.


Solid-state NMR studies of metal-free SOD1 fibrillar structures.

Banci L, Blaževitš O, Cantini F, Danielsson J, Lang L, Luchinat C, Mao J, Oliveberg M, Ravera E.

J Biol Inorg Chem. 2014 Jun;19(4-5):659-66. doi: 10.1007/s00775-014-1130-9. Epub 2014 Apr 10.


Direct detection of neuropeptide dynorphin A binding to the second extracellular loop of the κ opioid receptor using a soluble protein scaffold.

Björnerås J, Kurnik M, Oliveberg M, Gräslund A, Mäler L, Danielsson J.

FEBS J. 2014 Feb;281(3):814-24.


Studies toward communesin F: a Diels-Alder approach.

Danielsson J, Somfai P.

Org Lett. 2014 Feb 7;16(3):784-7. doi: 10.1021/ol403516s. Epub 2014 Jan 21.


Exploring the minimally frustrated energy landscape of unfolded ACBP.

Ozenne V, Noel JK, Heidarsson PO, Brander S, Poulsen FM, Jensen MR, Kragelund BB, Blackledge M, Danielsson J.

J Mol Biol. 2014 Feb 6;426(3):722-34. doi: 10.1016/j.jmb.2013.10.031. Epub 2013 Nov 7.


Functional expression of the TMEM16 family of calcium-activated chloride channels in airway smooth muscle.

Gallos G, Remy KE, Danielsson J, Funayama H, Fu XW, Chang HY, Yim P, Xu D, Emala CW Sr.

Am J Physiol Lung Cell Mol Physiol. 2013 Nov 1;305(9):L625-34. doi: 10.1152/ajplung.00068.2013. Epub 2013 Aug 30.


Biophysical studies of the amyloid β-peptide: interactions with metal ions and small molecules.

Wärmländer S, Tiiman A, Abelein A, Luo J, Jarvet J, Söderberg KL, Danielsson J, Gräslund A.

Chembiochem. 2013 Sep 23;14(14):1692-704. doi: 10.1002/cbic.201300262. Epub 2013 Aug 26. Review.


Pruning the ALS-associated protein SOD1 for in-cell NMR.

Danielsson J, Inomata K, Murayama S, Tochio H, Lang L, Shirakawa M, Oliveberg M.

J Am Chem Soc. 2013 Jul 17;135(28):10266-9. doi: 10.1021/ja404425r. Epub 2013 Jul 8.


Formation of dynamic soluble surfactant-induced amyloid β peptide aggregation intermediates.

Abelein A, Kaspersen JD, Nielsen SB, Jensen GV, Christiansen G, Pedersen JS, Danielsson J, Otzen DE, Gräslund A.

J Biol Chem. 2013 Aug 9;288(32):23518-28. doi: 10.1074/jbc.M113.470450. Epub 2013 Jun 17.


Individual and joint impacts of ethanol use, BMI, age and gender on serum gamma-glutamyltransferase levels in healthy volunteers.

Danielsson J, Kangastupa P, Laatikainen T, Aalto M, Niemelä O.

Int J Mol Sci. 2013 Jun 4;14(6):11929-41. doi: 10.3390/ijms140611929.


Dose- and gender-dependent interactions between coffee consumption and serum GGT activity in alcohol consumers.

Danielsson J, Kangastupa P, Laatikainen T, Aalto M, Niemelä O.

Alcohol Alcohol. 2013 May-Jun;48(3):303-7. doi: 10.1093/alcalc/agt017. Epub 2013 Mar 14.


Global structural motions from the strain of a single hydrogen bond.

Danielsson J, Awad W, Saraboji K, Kurnik M, Lang L, Leinartaite L, Marklund SL, Logan DT, Oliveberg M.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3829-34. doi: 10.1073/pnas.1217306110. Epub 2013 Feb 19.


Transient small molecule interactions kinetically modulate amyloid β peptide self-assembly.

Abelein A, Lang L, Lendel C, Gräslund A, Danielsson J.

FEBS Lett. 2012 Nov 16;586(22):3991-5. doi: 10.1016/j.febslet.2012.09.035. Epub 2012 Oct 9. Erratum in: FEBS Lett. 2013 May 2;587(9):1452.


Fibrillation precursor of superoxide dismutase 1 revealed by gradual tuning of the protein-folding equilibrium.

Lang L, Kurnik M, Danielsson J, Oliveberg M.

Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):17868-73. doi: 10.1073/pnas.1201795109. Epub 2012 Jul 13.


Cytotoxicity of superoxide dismutase 1 in cultured cells is linked to Zn2+ chelation.

Johansson AS, Vestling M, Zetterström P, Lang L, Leinartaitė L, Karlström M, Danielsson J, Marklund SL, Oliveberg M.

PLoS One. 2012;7(4):e36104. doi: 10.1371/journal.pone.0036104. Epub 2012 Apr 25.


Specific binding of a β-cyclodextrin dimer to the amyloid β peptide modulates the peptide aggregation process.

Wahlström A, Cukalevski R, Danielsson J, Jarvet J, Onagi H, Rebek J Jr, Linse S, Gräslund A.

Biochemistry. 2012 May 29;51(21):4280-9. doi: 10.1021/bi300341j. Epub 2012 May 17.


pH-dependence of the specific binding of Cu(II) and Zn(II) ions to the amyloid-β peptide.

Ghalebani L, Wahlström A, Danielsson J, Wärmländer SK, Gräslund A.

Biochem Biophys Res Commun. 2012 May 11;421(3):554-60. doi: 10.1016/j.bbrc.2012.04.043. Epub 2012 Apr 14.


Folding without charges.

Kurnik M, Hedberg L, Danielsson J, Oliveberg M.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5705-10. doi: 10.1073/pnas.1118640109. Epub 2012 Mar 27.


Trimming down a protein structure to its bare foldons: spatial organization of the cooperative unit.

Haglund E, Danielsson J, Kadhirvel S, Lindberg MO, Logan DT, Oliveberg M.

J Biol Chem. 2012 Jan 20;287(4):2731-8. doi: 10.1074/jbc.M111.312447. Epub 2011 Nov 22.


Cutting off functional loops from homodimeric enzyme superoxide dismutase 1 (SOD1) leaves monomeric β-barrels.

Danielsson J, Kurnik M, Lang L, Oliveberg M.

J Biol Chem. 2011 Sep 23;286(38):33070-83. doi: 10.1074/jbc.M111.251223. Epub 2011 Jun 23.


N-terminal engineering of amyloid-β-binding Affibody molecules yields improved chemical synthesis and higher binding affinity.

Lindgren J, Wahlström A, Danielsson J, Markova N, Ekblad C, Gräslund A, Abrahmsén L, Karlström AE, Wärmländer SK.

Protein Sci. 2010 Dec;19(12):2319-29. doi: 10.1002/pro.511.


Cooperative formation of native-like tertiary contacts in the ensemble of unfolded states of a four-helix protein.

Bruun SW, Iesmantavicius V, Danielsson J, Poulsen FM.

Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13306-11. doi: 10.1073/pnas.1003004107. Epub 2010 Jul 12.


Mukaiyama aldol addition to alpha-chloro-substituted aldehydes. Origin of the unexpected syn selectivity.

Borg T, Danielsson J, Somfai P.

Chem Commun (Camb). 2010 Feb 28;46(8):1281-3. doi: 10.1039/b922954j. Epub 2010 Jan 7.


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