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Items: 23


RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity.

Orozco SL, Daniels BP, Yatim N, Messmer MN, Quarato G, Chen-Harris H, Cullen SP, Snyder AG, Ralli-Jain P, Frase S, Tait SWG, Green DR, Albert ML, Oberst A.

Cell Rep. 2019 Aug 27;28(9):2275-2287.e5. doi: 10.1016/j.celrep.2019.07.077.


STING is required for host defense against neuropathological West Nile virus infection.

McGuckin Wuertz K, Treuting PM, Hemann EA, Esser-Nobis K, Snyder AG, Graham JB, Daniels BP, Wilkins C, Snyder JM, Voss KM, Oberst A, Lund J, Gale M Jr.

PLoS Pathog. 2019 Aug 15;15(8):e1007899. doi: 10.1371/journal.ppat.1007899. eCollection 2019 Aug.


Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity.

Snyder AG, Hubbard NW, Messmer MN, Kofman SB, Hagan CE, Orozco SL, Chiang K, Daniels BP, Baker D, Oberst A.

Sci Immunol. 2019 Jun 21;4(36). pii: eaaw2004. doi: 10.1126/sciimmunol.aaw2004.


The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons.

Daniels BP, Kofman SB, Smith JR, Norris GT, Snyder AG, Kolb JP, Gao X, Locasale JW, Martinez J, Gale M Jr, Loo YM, Oberst A.

Immunity. 2019 Jan 15;50(1):64-76.e4. doi: 10.1016/j.immuni.2018.11.017. Epub 2019 Jan 8.


RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation.

Daniels BP, Snyder AG, Olsen TM, Orozco S, Oguin TH 3rd, Tait SWG, Martinez J, Gale M Jr, Loo YM, Oberst A.

Cell. 2017 Apr 6;169(2):301-313.e11. doi: 10.1016/j.cell.2017.03.011. Epub 2017 Mar 30.


Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection.

Daniels BP, Jujjavarapu H, Durrant DM, Williams JL, Green RR, White JP, Lazear HM, Gale M Jr, Diamond MS, Klein RS.

J Clin Invest. 2017 Mar 1;127(3):843-856. doi: 10.1172/JCI88720. Epub 2017 Jan 30.


MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D.

Gutierrez KD, Davis MA, Daniels BP, Olsen TM, Ralli-Jain P, Tait SW, Gale M Jr, Oberst A.

J Immunol. 2017 Mar 1;198(5):2156-2164. doi: 10.4049/jimmunol.1601757. Epub 2017 Jan 27.


Plasmodium falciparum Histidine-Rich Protein II Compromises Brain Endothelial Barriers and May Promote Cerebral Malaria Pathogenesis.

Pal P, Daniels BP, Oskman A, Diamond MS, Klein RS, Goldberg DE.

MBio. 2016 Jun 7;7(3). pii: e00617-16. doi: 10.1128/mBio.00617-16.


CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system.

Durrant DM, Daniels BP, Pasieka T, Dorsey D, Klein RS.

J Neuroinflammation. 2015 Dec 15;12:233. doi: 10.1186/s12974-015-0447-9.


The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity.

Miner JJ, Daniels BP, Shrestha B, Proenca-Modena JL, Lew ED, Lazear HM, Gorman MJ, Lemke G, Klein RS, Diamond MS.

Nat Med. 2015 Dec;21(12):1464-72. doi: 10.1038/nm.3974. Epub 2015 Nov 2.


Knocking on Closed Doors: Host Interferons Dynamically Regulate Blood-Brain Barrier Function during Viral Infections of the Central Nervous System.

Daniels BP, Klein RS.

PLoS Pathog. 2015 Sep 17;11(9):e1005096. doi: 10.1371/journal.ppat.1005096. eCollection 2015 Sep. Review. No abstract available.


Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier.

Lazear HM, Daniels BP, Pinto AK, Huang AC, Vick SC, Doyle SE, Gale M Jr, Klein RS, Diamond MS.

Sci Transl Med. 2015 Apr 22;7(284):284ra59. doi: 10.1126/scitranslmed.aaa4304. Erratum in: Sci Transl Med. 2015 May 27;7(289):289er5.


Viral sensing at the blood-brain barrier: new roles for innate immunity at the CNS vasculature.

Daniels BP, Klein RS.

Clin Pharmacol Ther. 2015 Apr;97(4):372-9. doi: 10.1002/cpt.75. Epub 2015 Feb 26. Review.


An expanded task battery in the Morris water maze reveals effects of Toxoplasma gondii infection on learning and memory in rats.

Daniels BP, Sestito SR, Rouse ST.

Parasitol Int. 2015 Feb;64(1):5-12. doi: 10.1016/j.parint.2014.09.002. Epub 2014 Sep 9.


IL-1R1 signaling regulates CXCL12-mediated T cell localization and fate within the central nervous system during West Nile Virus encephalitis.

Durrant DM, Daniels BP, Klein RS.

J Immunol. 2014 Oct 15;193(8):4095-106. doi: 10.4049/jimmunol.1401192. Epub 2014 Sep 8.


Viral pathogen-associated molecular patterns regulate blood-brain barrier integrity via competing innate cytokine signals.

Daniels BP, Holman DW, Cruz-Orengo L, Jujjavarapu H, Durrant DM, Klein RS.

MBio. 2014 Aug 26;5(5):e01476-14. doi: 10.1128/mBio.01476-14.


Enhanced sphingosine-1-phosphate receptor 2 expression underlies female CNS autoimmunity susceptibility.

Cruz-Orengo L, Daniels BP, Dorsey D, Basak SA, Grajales-Reyes JG, McCandless EE, Piccio L, Schmidt RE, Cross AH, Crosby SD, Klein RS.

J Clin Invest. 2014 Jun;124(6):2571-84. doi: 10.1172/JCI73408. Epub 2014 May 8.


Targeting CXCR7/ACKR3 as a therapeutic strategy to promote remyelination in the adult central nervous system.

Williams JL, Patel JR, Daniels BP, Klein RS.

J Exp Med. 2014 May 5;211(5):791-9. doi: 10.1084/jem.20131224. Epub 2014 Apr 14.


Chemokines Referee Inflammation within the Central Nervous System during Infection and Disease.

Durrant DM, Williams JL, Daniels BP, Klein RS.

Adv Med. 2014;2014:806741. doi: 10.1155/2014/806741. Epub 2014 Sep 30. Review.


Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier.

Daniels BP, Cruz-Orengo L, Pasieka TJ, Couraud PO, Romero IA, Weksler B, Cooper JA, Doering TL, Klein RS.

J Neurosci Methods. 2013 Jan 15;212(1):173-9. doi: 10.1016/j.jneumeth.2012.10.001. Epub 2012 Oct 13.


2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo.

Szretter KJ, Daniels BP, Cho H, Gainey MD, Yokoyama WM, Gale M Jr, Virgin HW, Klein RS, Sen GC, Diamond MS.

PLoS Pathog. 2012;8(5):e1002698. doi: 10.1371/journal.ppat.1002698. Epub 2012 May 10.


Identification of the proximal erythroid promoter region of the mouse anion exchanger gene.

Sahr KE, Daniels BP, Hanspal M.

Blood. 1996 Dec 15;88(12):4500-9.


The structure and organization of the human erythroid anion exchanger (AE1) gene.

Sahr KE, Taylor WM, Daniels BP, Rubin HL, Jarolim P.

Genomics. 1994 Dec;24(3):491-501.


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