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Author Correction: Early Cellular Responses of Prostate Carcinoma Cells to Sepantronium Bromide (YM155) Involve Suppression of mTORC1 by AMPK.

Danielpour D, Gao Z, Zmina PM, Shankar E, Shultes BC, Jobava R, Welford SM, Hatzoglou M.

Sci Rep. 2019 Oct 10;9(1):14826. doi: 10.1038/s41598-019-51007-0.


JAB1/COPS5 is a putative oncogene that controls critical oncoproteins deregulated in prostate cancer.

Danielpour D, Purighalla S, Wang E, Zmina PM, Sarkar A, Zhou G.

Biochem Biophys Res Commun. 2019 Oct 15;518(2):374-380. doi: 10.1016/j.bbrc.2019.08.066. Epub 2019 Aug 18.


Early Cellular Responses of Prostate Carcinoma Cells to Sepantronium Bromide (YM155) Involve Suppression of mTORC1 by AMPK.

Danielpour D, Gao Z, Zmina PM, Shankar E, Shultes BC, Jobava R, Welford SM, Hatzoglou M.

Sci Rep. 2019 Aug 8;9(1):11541. doi: 10.1038/s41598-019-47573-y. Erratum in: Sci Rep. 2019 Oct 10;9(1):14826.


Neuroendocrine prostate carcinoma cells originate from the p63-expressing basal cells but not the pre-existing adenocarcinoma cells in mice.

Lee DK, Liu Y, Liao L, Li W, Danielpour D, Xu J.

Cell Res. 2019 May;29(5):420-422. doi: 10.1038/s41422-019-0149-4. Epub 2019 Feb 18. No abstract available.


HMBA is a putative HSP70 activator stimulating HEXIM1 expression that is down-regulated by estrogen.

Lama R, Gan C, Idippily N, Bobba V, Danielpour D, Montano M, Su B.

J Steroid Biochem Mol Biol. 2017 Apr;168:91-101. doi: 10.1016/j.jsbmb.2017.02.008. Epub 2017 Feb 14.


Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics-mitochondrial priming.

Thiagarajan PS, Wu X, Zhang W, Shi I, Bagai R, Leahy P, Feng Y, Veigl M, Lindner D, Danielpour D, Yin L, Rosell R, Bivona TG, Zhang Z, Ma PC.

Oncotarget. 2016 Dec 13;7(50):82013-82027. doi: 10.18632/oncotarget.13307.


A Signaling Network Controlling Androgenic Repression of c-Fos Protein in Prostate Adenocarcinoma Cells.

Shankar E, Song K, Corum SL, Bane KL, Wang H, Kao HY, Danielpour D.

J Biol Chem. 2016 Mar 11;291(11):5512-26. doi: 10.1074/jbc.M115.694877. Epub 2016 Jan 19.


Tocopherol transfer protein sensitizes prostate cancer cells to vitamin E.

Morley S, Thakur V, Danielpour D, Parker R, Arai H, Atkinson J, Barnholtz-Sloan J, Klein E, Manor D.

J Biol Chem. 2015 Oct 23;290(43):25848. doi: 10.1074/jbc.A110.169664. No abstract available.


Deptor enhances triple-negative breast cancer metastasis and chemoresistance through coupling to survivin expression.

Parvani JG, Davuluri G, Wendt MK, Espinosa C, Tian M, Danielpour D, Sossey-Alaoui K, Schiemann WP.

Neoplasia. 2015 Mar;17(3):317-28. doi: 10.1016/j.neo.2015.02.003.


HEXIM1 plays a critical role in the inhibition of the androgen receptor by anti-androgens.

Yeh IJ, Song K, Wittmann BM, Bai X, Danielpour D, Montano MM.

Biochem J. 2014 Sep 1;462(2):315-27. doi: 10.1042/BJ20140174.


Cited2, a transcriptional modulator protein, regulates metabolism in murine embryonic stem cells.

Li Q, Hakimi P, Liu X, Yu WM, Ye F, Fujioka H, Raza S, Shankar E, Tang F, Dunwoodie SL, Danielpour D, Hoppel CL, Ramírez-Bergeron DL, Qu CK, Hanson RW, Yang YC.

J Biol Chem. 2014 Jan 3;289(1):251-63. doi: 10.1074/jbc.M113.497594. Epub 2013 Nov 21.


Cited2 is required for the maintenance of glycolytic metabolism in adult hematopoietic stem cells.

Du J, Li Q, Tang F, Puchowitz MA, Fujioka H, Dunwoodie SL, Danielpour D, Yang YC.

Stem Cells Dev. 2014 Jan 15;23(2):83-94. doi: 10.1089/scd.2013.0370. Epub 2013 Nov 12.


Critical role of a survivin/TGF-β/mTORC1 axis in IGF-I-mediated growth of prostate epithelial cells.

Song K, Shankar E, Yang J, Bane KL, Wahdan-Alaswad R, Danielpour D.

PLoS One. 2013 May 1;8(5):e61896. doi: 10.1371/journal.pone.0061896. Print 2013.


Upregulation of SATB1 is associated with prostate cancer aggressiveness and disease progression.

Shukla S, Sharma H, Abbas A, MacLennan GT, Fu P, Danielpour D, Gupta S.

PLoS One. 2013;8(1):e53527. doi: 10.1371/journal.pone.0053527. Epub 2013 Jan 7.


TGF-β upregulates miR-181a expression to promote breast cancer metastasis.

Taylor MA, Sossey-Alaoui K, Thompson CL, Danielpour D, Schiemann WP.

J Clin Invest. 2013 Jan;123(1):150-63. doi: 10.1172/JCI64946. Epub 2012 Dec 17.


Inhibition of mTORC1 kinase activates Smads 1 and 5 but not Smad8 in human prostate cancer cells, mediating cytostatic response to rapamycin.

Wahdan-Alaswad RS, Bane KL, Song K, Shola DT, Garcia JA, Danielpour D.

Mol Cancer Res. 2012 Jun;10(6):821-33. doi: 10.1158/1541-7786.MCR-11-0615. Epub 2012 Mar 27. Erratum in: Mol Cancer Res. 2018 Jan;16(1):184.


HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency.

Du J, Chen Y, Li Q, Han X, Cheng C, Wang Z, Danielpour D, Dunwoodie SL, Bunting KD, Yang YC.

Blood. 2012 Mar 22;119(12):2789-98. doi: 10.1182/blood-2011-10-387902. Epub 2012 Feb 2.


Hic-5 controls BMP4 responses in prostate cancer cells through interacting with Smads 1, 5 and 8.

Shola DT, Wang H, Wahdan-Alaswad R, Danielpour D.

Oncogene. 2012 May 10;31(19):2480-90. doi: 10.1038/onc.2011.422. Epub 2011 Sep 26.


TGF-beta signaling engages an ATM-CHK2-p53-independent RAS-induced senescence and prevents malignant transformation in human mammary epithelial cells.

Cipriano R, Kan CE, Graham J, Danielpour D, Stampfer M, Jackson MW.

Proc Natl Acad Sci U S A. 2011 May 24;108(21):8668-73. doi: 10.1073/pnas.1015022108. Epub 2011 May 9.


The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activity.

Pasupuleti N, Matsuyama S, Voss O, Doseff AI, Song K, Danielpour D, Nagaraj RH.

Cell Death Dis. 2010;1:e31. doi: 10.1038/cddis.2010.3.


17-Beta-estradiol induces neoplastic transformation in prostatic epithelial cells.

Yu S, Zhang Y, Yuen MT, Zou C, Danielpour D, Chan FL.

Cancer Lett. 2011 May 1;304(1):8-20. doi: 10.1016/j.canlet.2011.01.003. Epub 2011 Feb 25.


Insulin-like growth factor I suppresses bone morphogenetic protein signaling in prostate cancer cells by activating mTOR signaling.

Wahdan-Alaswad RS, Song K, Krebs TL, Shola DT, Gomez JA, Matsuyama S, Danielpour D.

Cancer Res. 2010 Nov 15;70(22):9106-17. doi: 10.1158/0008-5472.CAN-10-1119. Epub 2010 Nov 9.


Tocopherol transfer protein sensitizes prostate cancer cells to vitamin E.

Morley S, Thakur V, Danielpour D, Parker R, Arai H, Atkinson J, Barnholtz-Sloan J, Klein E, Manor D.

J Biol Chem. 2010 Nov 12;285(46):35578-89. doi: 10.1074/jbc.M110.169664. Epub 2010 Sep 8. Erratum in: J Biol Chem. 2015 Oct 23;290(43):25848.


DHT selectively reverses Smad3-mediated/TGF-beta-induced responses through transcriptional down-regulation of Smad3 in prostate epithelial cells.

Song K, Wang H, Krebs TL, Wang B, Kelley TJ, Danielpour D.

Mol Endocrinol. 2010 Oct;24(10):2019-29. doi: 10.1210/me.2010-0165. Epub 2010 Aug 25.


TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer.

Araki S, Eitel JA, Batuello CN, Bijangi-Vishehsaraei K, Xie XJ, Danielpour D, Pollok KE, Boothman DA, Mayo LD.

J Clin Invest. 2010 Jan;120(1):290-302. doi: 10.1172/JCI39194. Epub 2009 Dec 1.


The C-terminus of interferon gamma receptor beta chain (IFNgammaR2) has antiapoptotic activity as a Bax inhibitor.

Gomez JA, Sun W, Gama V, Hajkova D, Yoshida T, Wu Z, Miyagi M, Pink JJ, Jackson MW, Danielpour D, Matsuyama S.

Cancer Biol Ther. 2009 Sep;8(18):1771-86. Epub 2009 Sep 20.


EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt.

Miao H, Li DQ, Mukherjee A, Guo H, Petty A, Cutter J, Basilion JP, Sedor J, Wu J, Danielpour D, Sloan AE, Cohen ML, Wang B.

Cancer Cell. 2009 Jul 7;16(1):9-20. doi: 10.1016/j.ccr.2009.04.009.


Critical role of Smad2 in tumor suppression and transforming growth factor-beta-induced apoptosis of prostate epithelial cells.

Yang J, Wahdan-Alaswad R, Danielpour D.

Cancer Res. 2009 Mar 15;69(6):2185-90. doi: 10.1158/0008-5472.CAN-08-3961. Epub 2009 Mar 10.


Hdm2 is a ubiquitin ligase of Ku70-Akt promotes cell survival by inhibiting Hdm2-dependent Ku70 destabilization.

Gama V, Gomez JA, Mayo LD, Jackson MW, Danielpour D, Song K, Haas AL, Laughlin MJ, Matsuyama S.

Cell Death Differ. 2009 May;16(5):758-69. doi: 10.1038/cdd.2009.6. Epub 2009 Feb 27.


Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55.

Wang H, Song K, Krebs TL, Yang J, Danielpour D.

Oncogene. 2008 Nov 20;27(54):6791-805. doi: 10.1038/onc.2008.291. Epub 2008 Sep 1.


Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies.

Garcia JA, Danielpour D.

Mol Cancer Ther. 2008 Jun;7(6):1347-54. doi: 10.1158/1535-7163.MCT-07-2408. Review.


Rb/E2F4 and Smad2/3 link survivin to TGF-beta-induced apoptosis and tumor progression.

Yang J, Song K, Krebs TL, Jackson MW, Danielpour D.

Oncogene. 2008 Sep 11;27(40):5326-38. doi: 10.1038/onc.2008.165. Epub 2008 May 26.


An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments.

Nam JS, Terabe M, Mamura M, Kang MJ, Chae H, Stuelten C, Kohn E, Tang B, Sabzevari H, Anver MR, Lawrence S, Danielpour D, Lonning S, Berzofsky JA, Wakefield LM.

Cancer Res. 2008 May 15;68(10):3835-43. doi: 10.1158/0008-5472.CAN-08-0215.


FLICE-like inhibitory protein blocks transforming growth factor beta 1-induced caspase activation and apoptosis in prostate epithelial cells.

Nastiuk KL, Yoo K, Lo K, Su K, Yeung P, Kutaka J, Danielpour D, Krolewski JJ.

Mol Cancer Res. 2008 Feb;6(2):231-42. doi: 10.1158/1541-7786.MCR-07-0386.


Overexpression of Bax induces down-regulation of store-operated calcium entry in prostate cancer cells.

Li N, Zheng L, Lin P, Danielpour D, Pan Z, Ma J.

J Cell Physiol. 2008 Jul;216(1):172-9. doi: 10.1002/jcp.21385.


Posterior Hox gene expression and differential androgen regulation in the developing and adult rat prostate lobes.

Huang L, Pu Y, Hepps D, Danielpour D, Prins GS.

Endocrinology. 2007 Mar;148(3):1235-45. Epub 2006 Nov 30.


ELAC2, a putative prostate cancer susceptibility gene product, potentiates TGF-beta/Smad-induced growth arrest of prostate cells.

Noda D, Itoh S, Watanabe Y, Inamitsu M, Dennler S, Itoh F, Koike S, Danielpour D, ten Dijke P, Kato M.

Oncogene. 2006 Sep 14;25(41):5591-600. Epub 2006 Apr 24.


Cited2 modulates TGF-beta-mediated upregulation of MMP9.

Chou YT, Wang H, Chen Y, Danielpour D, Yang YC.

Oncogene. 2006 Sep 7;25(40):5547-60. Epub 2006 Apr 17.


The presenilin-2 loop peptide perturbs intracellular Ca2+ homeostasis and accelerates apoptosis.

Cai C, Lin P, Cheung KH, Li N, Levchook C, Pan Z, Ferrante C, Boulianne GL, Foskett JK, Danielpour D, Ma J.

J Biol Chem. 2006 Jun 16;281(24):16649-55. Epub 2006 Apr 7.


Novel roles of Akt and mTOR in suppressing TGF-beta/ALK5-mediated Smad3 activation.

Song K, Wang H, Krebs TL, Danielpour D.

EMBO J. 2006 Jan 11;25(1):58-69. Epub 2005 Dec 15.


Cross-talk between IGF-I and TGF-beta signaling pathways.

Danielpour D, Song K.

Cytokine Growth Factor Rev. 2006 Feb-Apr;17(1-2):59-74. Epub 2005 Nov 16. Review.


Functions and regulation of transforming growth factor-beta (TGF-beta) in the prostate.

Danielpour D.

Eur J Cancer. 2005 Apr;41(6):846-57. Review.


Overexpression of Bax sensitizes prostate cancer cells to TGF-beta induced apoptosis.

Lin PH, Pan Z, Zheng L, Li N, Danielpour D, Ma JJ.

Cell Res. 2005 Mar;15(3):160-6.


Novel function of androgen receptor-associated protein 55/Hic-5 as a negative regulator of Smad3 signaling.

Wang H, Song K, Sponseller TL, Danielpour D.

J Biol Chem. 2005 Feb 18;280(7):5154-62. Epub 2004 Nov 23.


Proteome profile changes during transdifferentiation of NRP-152 rat prostatic basal epithelial cells.

Shim JH, Danielpour D, Lee C, Kim YS, Bahk YY, Yoo TK.

Mol Cells. 2004 Feb 29;17(1):108-16.


Defining regulatory elements in the human KAI1 (CD 82) metastasis suppressor gene.

Gao AC, Lou W, Dong JT, Barrett JC, Danielpour D, Isaacs JT.

Prostate. 2003 Dec 1;57(4):256-60.


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