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Items: 1 to 50 of 241

1.

Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease.

De Simone A, La Pietra V, Betari N, Petragnani N, Conte M, Daniele S, Pietrobono D, Martini C, Petralla S, Casadei R, Davani L, Frabetti F, Russomanno P, Novellino E, Montanari S, Tumiatti V, Ballerini P, Sarno F, Nebbioso A, Altucci L, Monti B, Andrisano V, Milelli A.

ACS Med Chem Lett. 2019 Feb 4;10(4):469-474. doi: 10.1021/acsmedchemlett.8b00507. eCollection 2019 Apr 11.

PMID:
30996781
2.

Restoration of brain circulation and cellular functions hours post-mortem.

Vrselja Z, Daniele SG, Silbereis J, Talpo F, Morozov YM, Sousa AMM, Tanaka BS, Skarica M, Pletikos M, Kaur N, Zhuang ZW, Liu Z, Alkawadri R, Sinusas AJ, Latham SR, Waxman SG, Sestan N.

Nature. 2019 Apr;568(7752):336-343. doi: 10.1038/s41586-019-1099-1. Epub 2019 Apr 17.

PMID:
30996318
3.

Synthesis of New GABAA Receptor Modulator with Pyrazolo[1,5-a]quinazoline (PQ) Scaffold.

Guerrini G, Vergelli C, Cantini N, Giovannoni MP, Daniele S, Mascia MP, Martini C, Crocetti L.

Int J Mol Sci. 2019 Mar 21;20(6). pii: E1438. doi: 10.3390/ijms20061438.

4.

Memantine prodrug as a new agent for Alzheimer's Disease.

Sestito S, Daniele S, Pietrobono D, Citi V, Bellusci L, Chiellini G, Calderone V, Martini C, Rapposelli S.

Sci Rep. 2019 Mar 15;9(1):4612. doi: 10.1038/s41598-019-40925-8.

5.

Potential Diagnostic Value of Red Blood Cells α-Synuclein Heteroaggregates in Alzheimer's Disease.

Baldacci F, Daniele S, Piccarducci R, Giampietri L, Pietrobono D, Giorgi FS, Nicoletti V, Frosini D, Libertini P, Lo Gerfo A, Petrozzi L, Donadio E, Betti L, Trincavelli ML, Siciliano G, Ceravolo R, Tognoni G, Bonuccelli U, Martini C.

Mol Neurobiol. 2019 Mar 2. doi: 10.1007/s12035-019-1531-4. [Epub ahead of print]

PMID:
30826968
6.

Fast determination of extra-virgin olive oil acidity by voltammetry and Partial Least Squares regression.

Baldo MA, Oliveri P, Fabris S, Malegori C, Daniele S.

Anal Chim Acta. 2019 May 16;1056:7-15. doi: 10.1016/j.aca.2018.12.050. Epub 2019 Jan 4.

PMID:
30797462
7.

Volatile aldehydes sensing in headspace using a room temperature ionic liquid-modified electrochemical microprobe.

Toniolo R, Dossi N, Bortolomeazzi R, Bonazza G, Daniele S.

Talanta. 2019 May 15;197:522-529. doi: 10.1016/j.talanta.2019.01.049. Epub 2019 Jan 14.

PMID:
30771971
8.

Temporal trends of abnormal myocardial perfusion imaging in a cohort of Italian subjects: Relation with cardiovascular risk factors.

Megna R, Zampella E, Assante R, Nappi C, Gaudieri V, Mannarino T, Cantoni V, Green R, Daniele S, Mainolfi CG, Acampa W, Petretta M, Cuocolo A.

J Nucl Cardiol. 2019 Feb 7. doi: 10.1007/s12350-019-01630-1. [Epub ahead of print]

PMID:
30734219
9.

Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts.

Daniele S, Giacomelli C, Pietrobono D, Barresi E, Piccarducci R, La Pietra V, Taliani S, Da Settimo F, Marinelli L, Novellino E, Martini C, Trincavelli ML.

Biochim Biophys Acta Mol Cell Res. 2019 May;1866(5):737-749. doi: 10.1016/j.bbamcr.2019.01.012. Epub 2019 Jan 28.

PMID:
30703414
10.

TiO₂-Based Hybrid Nanocomposites Modified by Phosphonate Molecules as Selective PAH Adsorbents.

Bou Orm N, Trieu QA, Daniele S.

Molecules. 2018 Nov 21;23(11). pii: E3046. doi: 10.3390/molecules23113046.

11.

Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A1 and A2B adenosine receptor subtypes.

Barresi E, Giacomelli C, Daniele S, Tonazzini I, Robello M, Salerno S, Piano I, Cosimelli B, Greco G, Da Settimo F, Martini C, Trincavelli ML, Taliani S.

Bioorg Med Chem. 2018 Dec 1;26(22):5885-5895. doi: 10.1016/j.bmc.2018.10.039. Epub 2018 Nov 1.

PMID:
30415894
12.

Brain ageing and neurodegenerative disease: The role of cellular waste management.

Daniele S, Giacomelli C, Martini C.

Biochem Pharmacol. 2018 Dec;158:207-216. doi: 10.1016/j.bcp.2018.10.030. Epub 2018 Oct 28. Review.

PMID:
30393045
13.

The instruments used by the Italian centres for cognitive disorders and dementia to diagnose mild cognitive impairment (MCI).

Limongi F, Noale M, Bianchetti A, Ferrara N, Padovani A, Scarpini E, Trabucchi M, Maggi S; MCI Working Group.

Aging Clin Exp Res. 2019 Jan;31(1):101-107. doi: 10.1007/s40520-018-1032-8. Epub 2018 Sep 3.

PMID:
30178442
14.

Long-term prognostic value of low-dose normal stress-only myocardial perfusion imaging by wide beam reconstruction: A competing risk analysis.

Nappi C, Acampa W, Nicolai E, Daniele S, Zampella E, Assante R, Gaudieri V, Mannarino T, Petretta M, Cuocolo A.

J Nucl Cardiol. 2018 Jul 19. doi: 10.1007/s12350-018-1373-x. [Epub ahead of print]

PMID:
30027504
15.

Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects.

Daniele S, Costa B, Pietrobono D, Giacomelli C, Iofrida C, Trincavelli ML, Fusi J, Franzoni F, Martini C.

Oxid Med Cell Longev. 2018 Apr 15;2018:3740345. doi: 10.1155/2018/3740345. eCollection 2018.

16.

Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme.

Merlino F, Daniele S, La Pietra V, Di Maro S, Di Leva FS, Brancaccio D, Tomassi S, Giuntini S, Cerofolini L, Fragai M, Luchinat C, Reichart F, Cavallini C, Costa B, Piccarducci R, Taliani S, Da Settimo F, Martini C, Kessler H, Novellino E, Marinelli L.

J Med Chem. 2018 Jun 14;61(11):4791-4809. doi: 10.1021/acs.jmedchem.8b00004. Epub 2018 Jun 4.

PMID:
29775303
17.

Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: the use of natural compounds as modulatory agents.

Giacomelli C, Natali L, Nisi M, De Leo M, Daniele S, Costa B, Graziani F, Gabriele M, Braca A, Trincavelli ML, Martini C.

Stem Cell Res Ther. 2018 May 11;9(1):135. doi: 10.1186/s13287-018-0880-7.

18.

A new class of pyrazolo[5,1-c][1,2,4]triazines as γ-aminobutyric type A (GABAA) receptor subtype ligand: synthesis and pharmacological evaluation.

Guerrini G, Ciciani G, Daniele S, Martini C, Costagli C, Guarino C, Selleri S.

Bioorg Med Chem. 2018 May 15;26(9):2475-2487. doi: 10.1016/j.bmc.2018.04.011. Epub 2018 Apr 4.

PMID:
29650463
19.

An in vitro comparative study of the antioxidant activity and SIRT1 modulation of natural compounds.

Fusi J, Bianchi S, Daniele S, Pellegrini S, Martini C, Galetta F, Giovannini L, Franzoni F.

Biomed Pharmacother. 2018 May;101:805-819. doi: 10.1016/j.biopha.2018.03.006. Epub 2018 Mar 22.

20.

CDK6 inhibits white to beige fat transition by suppressing RUNX1.

Hou X, Zhang Y, Li W, Hu AJ, Luo C, Zhou W, Hu JK, Daniele SG, Wang J, Sheng J, Fan Y, Greenberg AS, Farmer SR, Hu MG.

Nat Commun. 2018 Mar 9;9(1):1023. doi: 10.1038/s41467-018-03451-1.

21.

α-Synuclein Heterocomplexes with β-Amyloid Are Increased in Red Blood Cells of Parkinson's Disease Patients and Correlate with Disease Severity.

Daniele S, Frosini D, Pietrobono D, Petrozzi L, Lo Gerfo A, Baldacci F, Fusi J, Giacomelli C, Siciliano G, Trincavelli ML, Franzoni F, Ceravolo R, Martini C, Bonuccelli U.

Front Mol Neurosci. 2018 Feb 22;11:53. doi: 10.3389/fnmol.2018.00053. eCollection 2018.

22.

The A2B Adenosine Receptor Modulates the Epithelial- Mesenchymal Transition through the Balance of cAMP/PKA and MAPK/ERK Pathway Activation in Human Epithelial Lung Cells.

Giacomelli C, Daniele S, Romei C, Tavanti L, Neri T, Piano I, Celi A, Martini C, Trincavelli ML.

Front Pharmacol. 2018 Jan 31;9:54. doi: 10.3389/fphar.2018.00054. eCollection 2018.

23.

α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise.

Daniele S, Pietrobono D, Fusi J, Lo Gerfo A, Cerri E, Chico L, Iofrida C, Petrozzi L, Baldacci F, Giacomelli C, Galetta F, Siciliano G, Bonuccelli U, Trincavelli ML, Franzoni F, Martini C.

Front Aging Neurosci. 2018 Jan 30;10:17. doi: 10.3389/fnagi.2018.00017. eCollection 2018.

24.

Long-Distance, Nonstop Neonatal Transport From Shanghai, China, to Genoa, Italy.

Bellini C, Serveli S, A L, M P, S D, Ramenghi LA, Cinti T, Campone F.

Air Med J. 2018 Jan - Feb;37(1):67-70. doi: 10.1016/j.amj.2017.09.004. Epub 2017 Nov 6.

PMID:
29332782
25.

The 'Charter of Rights for Family Caregivers'. The role and importance of the caregiver: an Italian proposal.

Antonella S, Flavia V, Daniela T, Giuseppe T, Daniele S.

ESMO Open. 2017 Nov 4;2(5):e000256. doi: 10.1136/esmoopen-2017-000256. eCollection 2017.

26.

Identification of a New Pyrazolo[1,5-a]quinazoline Ligand Highly Affine to γ-Aminobutyric Type A (GABAA) Receptor Subtype with Anxiolytic-Like and Antihyperalgesic Activity.

Guerrini G, Ciciani G, Crocetti L, Daniele S, Ghelardini C, Giovannoni MP, Iacovone A, Di Cesare Mannelli L, Martini C, Vergelli C.

J Med Chem. 2017 Dec 14;60(23):9691-9702. doi: 10.1021/acs.jmedchem.7b01151. Epub 2017 Nov 22.

PMID:
29125291
27.

Carnosol controls the human glioblastoma stemness features through the epithelial-mesenchymal transition modulation and the induction of cancer stem cell apoptosis.

Giacomelli C, Daniele S, Natali L, Iofrida C, Flamini G, Braca A, Trincavelli ML, Martini C.

Sci Rep. 2017 Nov 9;7(1):15174. doi: 10.1038/s41598-017-15360-2.

28.

Asymmetrically substituted triazenes as poor electron donor ligands in the precursor chemistry of iron(ii) for iron-based metallic and intermetallic nanocrystals.

Soussi K, Mishra S, Jeanneau E, Millet JM, Daniele S.

Dalton Trans. 2017 Oct 14;46(38):13055-13064. doi: 10.1039/c7dt02755a. Epub 2017 Sep 22.

PMID:
28937169
29.

Computer-Aided Identification and Lead Optimization of Dual Murine Double Minute 2 and 4 Binders: Structure-Activity Relationship Studies and Pharmacological Activity.

Giustiniano M, Daniele S, Pelliccia S, La Pietra V, Pietrobono D, Brancaccio D, Cosconati S, Messere A, Giuntini S, Cerofolini L, Fragai M, Luchinat C, Taliani S, La Regina G, Da Settimo F, Silvestri R, Martini C, Novellino E, Marinelli L.

J Med Chem. 2017 Oct 12;60(19):8115-8130. doi: 10.1021/acs.jmedchem.7b00912. Epub 2017 Sep 30.

PMID:
28921985
30.

Influence of physical exercise on β-amyloid, α-synuclein and tau accumulation: an in vitro model of oxidative stress in human red blood cells.

Iofrida C, Daniele S, Pietrobono D, Fusi J, Galetta F, Trincavelli ML, Bonuccelli U, Franzoni F, Martini C.

Arch Ital Biol. 2017 Jul 1;155(1-2):33-42. doi: 10.12871/000398292017124.

PMID:
28715596
31.

Physical Exercise Improves Total Antioxidant Capacity and Gene Expression in Rat Hippocampal Tissue.

Franzoni F, Federighi G, Fusi J, Agosta V, Cerri E, Banducci R, Petrocchi A, Bernardi R, Innocenti A, Pruneti C, Daniele S, Pellegrini S, Martini C, Scuri R, Galetta F.

Arch Ital Biol. 2017 Jul 1;155(1-2):1-10. doi: 10.12871/000398292017121.

PMID:
28715593
32.

Reduced {001}-TiO2-x photocatalysts: noble-metal-free CO2 photoreduction for selective CH4 evolution.

Fang W, Khrouz L, Zhou Y, Shen B, Dong C, Xing M, Mishra S, Daniele S, Zhang J.

Phys Chem Chem Phys. 2017 May 31;19(21):13875-13881. doi: 10.1039/c7cp01212h.

PMID:
28513732
33.

α-Synuclein Aggregates with β-Amyloid or Tau in Human Red Blood Cells: Correlation with Antioxidant Capability and Physical Exercise in Human Healthy Subjects.

Daniele S, Pietrobono D, Fusi J, Iofrida C, Chico L, Petrozzi L, Gerfo AL, Baldacci F, Galetta F, Siciliano G, Bonuccelli U, Santoro G, Trincavelli ML, Franzoni F, Martini C.

Mol Neurobiol. 2018 Mar;55(3):2653-2675. doi: 10.1007/s12035-017-0523-5. Epub 2017 Apr 18.

PMID:
28421539
34.

Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells.

Daniele S, Pietrobono D, Costa B, Giustiniano M, La Pietra V, Giacomelli C, La Regina G, Silvestri R, Taliani S, Trincavelli ML, Da Settimo F, Novellino E, Martini C, Marinelli L.

ACS Chem Neurosci. 2018 Jan 17;9(1):85-99. doi: 10.1021/acschemneuro.7b00023. Epub 2017 Apr 11.

PMID:
28368610
35.

Integrated socio-hydrogeological approach to tackle nitrate contamination in groundwater resources. The case of Grombalia Basin (Tunisia).

Re V, Sacchi E, Kammoun S, Tringali C, Trabelsi R, Zouari K, Daniele S.

Sci Total Environ. 2017 Sep 1;593-594:664-676. doi: 10.1016/j.scitotenv.2017.03.151. Epub 2017 Mar 28.

PMID:
28363179
36.

Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation.

Conant K, Daniele S, Bozzelli PL, Abdi T, Edwards A, Szklarczyk A, Olchefske I, Ottenheimer D, Maguire-Zeiss K.

J Neuroinflammation. 2017 Mar 17;14(1):56. doi: 10.1186/s12974-017-0827-4.

37.

An extracellular polymeric substance quickly chelates mercury(II) with N-heterocyclic groups.

Baldi F, Gallo M, Daniele S, Battistel D, Faleri C, Kodre A, Arčon I.

Chemosphere. 2017 Jun;176:296-304. doi: 10.1016/j.chemosphere.2017.02.093. Epub 2017 Feb 20.

PMID:
28273537
38.

Synthesis and pharmacological evaluation of pyrazolo[1,5-a]pyrimidin-7(4H)-one derivatives as potential GABAA-R ligands.

Guerrini G, Ciciani G, Daniele S, Di Cesare Mannelli L, Ghelardini C, Martini C, Selleri S.

Bioorg Med Chem. 2017 Mar 15;25(6):1901-1906. doi: 10.1016/j.bmc.2017.02.013. Epub 2017 Feb 11.

PMID:
28237554
39.

Potential biomarkers and novel pharmacological targets in protein aggregation-related neurodegenerative diseases.

Giacomelli C, Daniele S, Martini C.

Biochem Pharmacol. 2017 May 1;131:1-15. doi: 10.1016/j.bcp.2017.01.017. Epub 2017 Jan 31. Review.

PMID:
28159621
40.

Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals.

Daniele S, Natali L, Giacomelli C, Campiglia P, Novellino E, Martini C, Trincavelli ML.

Mol Cell Biol. 2017 Mar 31;37(8). pii: e00442-16. doi: 10.1128/MCB.00442-16. Print 2017 Apr 15.

41.

A broad mercury resistant strain of Pseudomonas putida secretes pyoverdine under limited iron conditions and high mercury concentrations.

Baldi F, Gallo M, Battistel D, Barbaro E, Gambaro A, Daniele S.

Biometals. 2016 Dec;29(6):1097-1106. Epub 2016 Nov 15.

PMID:
27848043
42.

Antiphospholipid and antioangiogenic activity in females with recurrent miscarriage and antiphospholipid syndrome.

Pelusa HF, Pezzarini E, Basiglio CL, Musuruana J, Bearzotti M, Svetaz MJ, Daniele SM, Bottai H, Arriaga SM.

Ann Clin Biochem. 2017 Sep;54(5):577-583. doi: 10.1177/0004563216672248. Epub 2016 Sep 16.

PMID:
27638930
43.

Long-term prognostic value of coronary artery calcium scanning, coronary computed tomographic angiography and stress myocardial perfusion imaging in patients with suspected coronary artery disease.

Nappi C, Nicolai E, Daniele S, Acampa W, Gaudieri V, Assante R, Zampella E, Segreto S, Imbriaco M, Petretta M, Salvatore M, Cuocolo A.

J Nucl Cardiol. 2018 Jun;25(3):833-841. doi: 10.1007/s12350-016-0657-2. Epub 2016 Nov 1.

PMID:
27804072
44.

Dual Inhibition of PDK1 and Aurora Kinase A: An Effective Strategy to Induce Differentiation and Apoptosis of Human Glioblastoma Multiforme Stem Cells.

Daniele S, Sestito S, Pietrobono D, Giacomelli C, Chiellini G, Di Maio D, Marinelli L, Novellino E, Martini C, Rapposelli S.

ACS Chem Neurosci. 2017 Jan 18;8(1):100-114. doi: 10.1021/acschemneuro.6b00251. Epub 2016 Nov 10.

PMID:
27797168
45.

A novel electroanalytical approach based on the use of a room temperature ionic liquid for the determination of olive oil acidity.

Baldo MA, Oliveri P, Simonetti R, Daniele S.

Talanta. 2016 Dec 1;161:881-887. doi: 10.1016/j.talanta.2016.09.045. Epub 2016 Sep 17.

PMID:
27769498
46.

An Effective Virtual Screening Protocol To Identify Promising p53-MDM2 Inhibitors.

Tortorella P, Laghezza A, Durante M, Gomez-Monterrey I, Bertamino A, Campiglia P, Loiodice F, Daniele S, Martini C, Agamennone M.

J Chem Inf Model. 2016 Jun 27;56(6):1216-27. doi: 10.1021/acs.jcim.5b00747. Epub 2016 Jun 7.

PMID:
27269808
47.

Human Neural Stem Cell Aging Is Counteracted by α-Glycerylphosphorylethanolamine.

Daniele S, Da Pozzo E, Iofrida C, Martini C.

ACS Chem Neurosci. 2016 Jul 20;7(7):952-63. doi: 10.1021/acschemneuro.6b00078. Epub 2016 May 31.

PMID:
27168476
48.

Toward PET imaging of A2B adenosine receptors: a carbon-11 labeled triazinobenzimidazole tracer: Synthesis and imaging of a new A2B PET tracer.

Petroni D, Giacomelli C, Taliani S, Barresi E, Robello M, Daniele S, Bartoli A, Burchielli S, Pardini S, Salvadori PA, Da Settimo F, Martini C, Trincavelli ML, Menichetti L.

Nucl Med Biol. 2016 May;43(5):309-17. doi: 10.1016/j.nucmedbio.2016.02.005. Epub 2016 Feb 27.

PMID:
27150034
49.

Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma.

Sestito S, Daniele S, Nesi G, Zappelli E, Di Maio D, Marinelli L, Digiacomo M, Lapucci A, Martini C, Novellino E, Rapposelli S.

Eur J Med Chem. 2016 Aug 8;118:47-63. doi: 10.1016/j.ejmech.2016.04.003. Epub 2016 Apr 20.

PMID:
27123901
50.

A Facile Molecular Precursor-based Synthesis of Ag2 Se Nanoparticles and Its Composites with TiO2 for Enhanced Photocatalytic Activity.

Mishra S, Du D, Jeanneau E, Dappozze F, Guillard C, Zhang J, Daniele S.

Chem Asian J. 2016 Jun 6;11(11):1658-63. doi: 10.1002/asia.201600157. Epub 2016 May 19.

PMID:
27123779

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