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Items: 1 to 50 of 167

1.

Serotonin receptors of 5-HT2 type in the hypothalamic arcuate nuclei (ARC) positively regulate liver cytochrome P450 via stimulation of the growth hormone-releasing hormone - growth hormone (GHRH-GH) hormonal pathway.

Bromek E, Rysz M, Haduch A, Daniel WA.

Drug Metab Dispos. 2018 Dec 5. pii: dmd.118.083808. doi: 10.1124/dmd.118.083808. [Epub ahead of print]

PMID:
30518657
2.

The engagement of brain cytochrome P450 in the metabolism of endogenous neuroactive substrates: a possible role in mental disorders.

Haduch A, Daniel WA.

Drug Metab Rev. 2018 Dec 2:1-41. doi: 10.1080/03602532.2018.1554674. [Epub ahead of print]

PMID:
30501426
3.

The activity of brain and liver cytochrome P450 2D (CYP2D) is differently affected by antidepressants in the chronic mild stress (CMS) model of depression in the rat.

Haduch A, Rysz M, Papp M, Daniel WA.

Biochem Pharmacol. 2018 Oct;156:398-405. doi: 10.1016/j.bcp.2018.09.005. Epub 2018 Sep 7.

PMID:
30195732
4.

Activation of 5-HT1A Receptors in the Hypothalamic Paraventricular Nuclei Negatively Regulates Cytochrome P450 Expression and Activity in Rat Liver.

Bromek E, Rysz M, Haduch A, Wójcikowski J, Daniel WA.

Drug Metab Dispos. 2018 Jun;46(6):786-793. doi: 10.1124/dmd.117.079632. Epub 2018 Mar 19.

PMID:
29555828
5.

Novel multi-target azinesulfonamides of cyclic amine derivatives as potential antipsychotics with pro-social and pro-cognitive effects.

Zajdel P, Kos T, Marciniec K, Satała G, Canale V, Kamiński K, Hołuj M, Lenda T, Koralewski R, Bednarski M, Nowiński L, Wójcikowski J, Daniel WA, Nikiforuk A, Nalepa I, Chmielarz P, Kuśmierczyk J, Bojarski AJ, Popik P.

Eur J Med Chem. 2018 Feb 10;145:790-804. doi: 10.1016/j.ejmech.2018.01.002. Epub 2018 Jan 3.

PMID:
29407591
6.

The Effect of Chronic Treatment with Lurasidone on Rat Liver Cytochrome P450 Expression and Activity in the Chronic Mild Stress Model of Depression.

Kot M, Haduch A, Papp M, Daniel WA.

Drug Metab Dispos. 2017 Dec;45(12):1336-1344. doi: 10.1124/dmd.117.077826. Epub 2017 Sep 21.

7.

N1-Azinylsulfonyl-1H-indoles: 5-HT6 Receptor Antagonists with Procognitive and Antidepressant-Like Properties.

Zajdel P, Marciniec K, Satała G, Canale V, Kos T, Partyka A, Jastrzębska-Więsek M, Wesołowska A, Basińska-Ziobroń A, Wójcikowski J, Daniel WA, Bojarski AJ, Popik P.

ACS Med Chem Lett. 2016 Apr 7;7(6):618-22. doi: 10.1021/acsmedchemlett.6b00056. eCollection 2016 Jun 9.

8.

The reverse role of the hypothalamic paraventricular (PVN) and arcuate (ARC) nuclei in the central serotonergic regulation of the liver cytochrome P450 isoform CYP2C11.

Rysz M, Bromek E, Haduch A, Liskova B, Wójcikowski J, Daniel WA.

Biochem Pharmacol. 2016 Jul 15;112:82-9. doi: 10.1016/j.bcp.2016.04.017. Epub 2016 Apr 29.

PMID:
27137992
9.

Desipramine administered chronically inhibits lipopolysaccharide-stimulated production of IL-1β in the brain and plasma of rats.

Obuchowicz E, Prymus A, Bielecka AM, Drzyzga Ł, Paul-Samojedny M, Kot M, Daniel WA.

Cytokine. 2016 Apr;80:26-34. doi: 10.1016/j.cyto.2015.10.012. Epub 2016 Mar 2.

PMID:
26937856
10.

Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain.

Haduch A, Bromek E, Wójcikowski J, Gołembiowska K, Daniel WA.

Drug Metab Dispos. 2016 Mar;44(3):445-52. doi: 10.1124/dmd.115.067413.

11.

Activation of brain serotonergic system by repeated intracerebral administration of 5-hydroxytryptophan (5-HTP) decreases the expression and activity of liver cytochrome P450.

Rysz M, Bromek E, Daniel WA.

Biochem Pharmacol. 2016 Jan 1;99:113-22. doi: 10.1016/j.bcp.2015.11.014. Epub 2015 Nov 12.

PMID:
26581122
12.

Inhibition of human cytochrome P450 isoenzymes by a phenothiazine neuroleptic levomepromazine: An in vitro study.

Basińska-Ziobroń A, Daniel WA, Wójcikowski J.

Pharmacol Rep. 2015 Dec;67(6):1178-82. doi: 10.1016/j.pharep.2015.04.005. Epub 2015 Apr 23.

PMID:
26481538
13.

Disruption of glucocorticoid receptors in the noradrenergic system leads to BDNF up-regulation and altered serotonergic transmission associated with a depressive-like phenotype in female GR(DBHCre) mice.

Chmielarz P, Kreiner G, Kot M, Zelek-Molik A, Kowalska M, Bagińska M, Daniel WA, Nalepa I.

Pharmacol Biochem Behav. 2015 Oct;137:69-77. doi: 10.1016/j.pbb.2015.08.001. Epub 2015 Aug 7.

PMID:
26261018
14.

Cocaine self-administration in Wistar-Kyoto rats: a behavioral and biochemical analysis.

Jastrzębska J, Frankowska M, Szumiec Ł, Sadakierska-Chudy A, Haduch A, Smaga I, Bystrowska B, Daniel WA, Filip M.

Behav Brain Res. 2015 Oct 15;293:62-73. doi: 10.1016/j.bbr.2015.06.040. Epub 2015 Jul 17.

PMID:
26192911
15.

Damage to the Brain Serotonergic System Increases the Expression of Liver Cytochrome P450.

Rysz M, Bromek E, Haduch A, Sadakierska-Chudy A, Daniel WA.

Drug Metab Dispos. 2015 Sep;43(9):1345-52. doi: 10.1124/dmd.115.064980. Epub 2015 Jun 9.

16.

The role of the dorsal noradrenergic pathway of the brain (locus coeruleus) in the regulation of liver cytochrome P450 activity.

Kot M, Sadakierska-Chudy A, Haduch A, Rysz M, Bromek E, Gołembiowska K, Daniel WA.

Eur J Pharmacol. 2015 Mar 15;751:34-41. doi: 10.1016/j.ejphar.2015.01.014. Epub 2015 Jan 28.

PMID:
25637782
17.

The cytochrome P450 2D-mediated formation of serotonin from 5-methoxytryptamine in the brain in vivo: a microdialysis study.

Haduch A, Bromek E, Kot M, Kamińska K, Gołembiowska K, Daniel WA.

J Neurochem. 2015 Apr;133(1):83-92. doi: 10.1111/jnc.13031. Epub 2015 Feb 8.

18.

The influence of amitriptyline and carbamazepine on levomepromazine metabolism in human liver: an in vitro study.

Wójcikowski J, Basińska A, Boksa J, Daniel WA.

Pharmacol Rep. 2014 Dec;66(6):1122-6. doi: 10.1016/j.pharep.2014.07.012. Epub 2014 Aug 7.

PMID:
25443744
19.

The cytochrome P450-catalyzed metabolism of levomepromazine: a phenothiazine neuroleptic with a wide spectrum of clinical application.

Wójcikowski J, Basińska A, Daniel WA.

Biochem Pharmacol. 2014 Jul 15;90(2):188-95. doi: 10.1016/j.bcp.2014.05.005. Epub 2014 May 16.

PMID:
24841887
20.

Role of brain cytochrome P450 (CYP2D) in the metabolism of monoaminergic neurotransmitters.

Anna Haduch A, Bromek E, Daniel WA.

Pharmacol Rep. 2013;65(6):1519-28. Review.

21.

Gender-dependent activity of CYP3A is indirectly modified by GR in the noradrenergic system.

Kot M, Kreiner G, Chmielarz P, Kuśmierczyk J, Nalepa I, Daniel WA.

Pharmacol Rep. 2013;65(5):1431-4.

22.

Effect of antidepressant drugs on cytochrome P450 2C11 (CYP2C11) in rat liver.

Wójcikowski J, Haduch A, Daniel WA.

Pharmacol Rep. 2013;65(5):1247-55.

23.

Involvement of the paraventricular (PVN) and arcuate (ARC) nuclei of the hypothalamus in the central noradrenergic regulation of liver cytochrome P450.

Bromek E, Wójcikowski J, Daniel WA.

Biochem Pharmacol. 2013 Dec 1;86(11):1614-20. doi: 10.1016/j.bcp.2013.09.006. Epub 2013 Sep 17.

PMID:
24051135
24.

The role of brain noradrenergic system in the regulation of liver cytochrome P450 expression.

Sadakierska-Chudy A, Haduch A, Rysz M, Gołembiowska K, Daniel WA.

Biochem Pharmacol. 2013 Sep 15;86(6):800-7. doi: 10.1016/j.bcp.2013.07.017. Epub 2013 Aug 4.

PMID:
23924605
25.
26.

Effect of classic and atypical neuroleptics on cytochrome P450 3A (CYP3A) in rat liver.

Wójcikowski J, Haduch A, Daniel WA.

Pharmacol Rep. 2012;64(6):1411-8.

27.

The catalytic competence of cytochrome P450 in the synthesis of serotonin from 5-methoxytryptamine in the brain: an in vitro study.

Haduch A, Bromek E, Sadakierska-Chudy A, Wójcikowski J, Daniel WA.

Pharmacol Res. 2013 Jan;67(1):53-9. doi: 10.1016/j.phrs.2012.10.009. Epub 2012 Oct 23.

PMID:
23098818
28.

Simultaneous alterations of brain and plasma serotonin concentrations and liver cytochrome P450 in rats fed on a tryptophan-free diet.

Kot M, Pilc A, Daniel WA.

Pharmacol Res. 2012 Oct;66(4):292-9. doi: 10.1016/j.phrs.2012.06.009. Epub 2012 Jun 27.

PMID:
22749902
29.

Effect of neuroleptics on cytochrome P450 2C11 (CYP2C11) in rat liver.

Haduch A, Wójcikowski J, Daniel WA.

Pharmacol Rep. 2011;63(6):1491-9.

30.

Cytochrome P450 is regulated by noradrenergic and serotonergic systems.

Kot M, Daniel WA.

Pharmacol Res. 2011 Oct;64(4):371-80. doi: 10.1016/j.phrs.2011.06.020. Epub 2011 Jun 30.

PMID:
21742037
31.

Cytochrome P450 mediates dopamine formation in the brain in vivo.

Bromek E, Haduch A, Gołembiowska K, Daniel WA.

J Neurochem. 2011 Sep;118(5):806-15. doi: 10.1111/j.1471-4159.2011.07339.x. Epub 2011 Jul 14.

32.

The role of the nervous system in the regulation of liver cytochrome p450.

Wójcikowski J, Daniel WA.

Curr Drug Metab. 2011 Feb;12(2):124-38. Review.

PMID:
21401511
33.

Effects of low doses of intracerebroventricular 6-OHDA on the levels of monoaminergic neurotransmitters in rat brain structures.

Sadakierska-Chudy A, Haduch A, Gołembiowska K, Daniel WA.

Pharmacol Rep. 2010 Nov-Dec;62(6):1225-30.

34.
35.

The effect of psychotropic drugs on cytochrome P450 2D (CYP2D) in rat brain.

Haduch A, Bromek E, Daniel WA.

Eur J Pharmacol. 2011 Jan 25;651(1-3):51-8. doi: 10.1016/j.ejphar.2010.10.077. Epub 2010 Nov 27.

PMID:
21115002
36.
39.

The ability of cytochrome P450 2D isoforms to synthesize dopamine in the brain: An in vitro study.

Bromek E, Haduch A, Daniel WA.

Eur J Pharmacol. 2010 Jan 25;626(2-3):171-8. doi: 10.1016/j.ejphar.2009.09.062. Epub 2009 Oct 8.

PMID:
19818757
40.

The brain dopaminergic system as an important center regulating liver cytochrome P450 in the rat.

Wójcikowski J, Daniel WA.

Expert Opin Drug Metab Toxicol. 2009 Jun;5(6):631-45. doi: 10.1517/17425250902973703. Review.

PMID:
19442036
41.
42.
43.

Caffeine as a marker substrate for testing cytochrome P450 activity in human and rat.

Kot M, Daniel WA.

Pharmacol Rep. 2008 Nov-Dec;60(6):789-97. Review.

44.
45.

Regulation of liver cytochrome P450 by activation of brain dopaminergic system: physiological and pharmacological implications.

Wójcikowski J, Gołembiowska K, Daniel WA.

Biochem Pharmacol. 2008 Jul 15;76(2):258-67. doi: 10.1016/j.bcp.2008.04.016. Epub 2008 May 3.

PMID:
18538745
46.

Brain levels of dextromethorphan and the intensity of opioid withdrawal in mice.

Bisaga A, Kos T, Wójcikowski J, Daniel WA, Popik P.

Drug Alcohol Depend. 2008 May 1;95(1-2):147-51. doi: 10.1016/j.drugalcdep.2008.01.007. Epub 2008 Mar 6.

PMID:
18328640
47.

Relative contribution of rat cytochrome P450 isoforms to the metabolism of caffeine: the pathway and concentration dependence.

Kot M, Daniel WA.

Biochem Pharmacol. 2008 Apr 1;75(7):1538-49. doi: 10.1016/j.bcp.2007.12.017. Epub 2008 Jan 5.

PMID:
18279840
48.

Amantadine as an additive treatment in patients suffering from drug-resistant unipolar depression.

Rogóz Z, Skuza G, Daniel WA, Wójcikowski J, Dudek D, Wróbel A.

Pharmacol Rep. 2007 Nov-Dec;59(6):778-84.

49.

Caffeine metabolism during prolonged treatment of rats with antidepressant drugs.

Kot M, Wójcikowski J, Daniel WA.

Pharmacol Rep. 2007 Nov-Dec;59(6):727-33.

50.

The activity of cytochrome P450 CYP2B in rat liver during neuroleptic treatment.

Haduch A, Wójcikowski J, Daniel WA.

Pharmacol Rep. 2007 Sep-Oct;59(5):606-12.

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