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Items: 1 to 50 of 53

1.

Terminally Differentiated Effector Memory CD8+ T Cells Identify Kidney Transplant Recipients at High Risk of Graft Failure.

Jacquemont L, Tilly G, Yap M, Doan-Ngoc TM, Danger R, Guérif P, Delbos F, Martinet B, Giral M, Foucher Y, Brouard S, Degauque N.

J Am Soc Nephrol. 2020 Mar 12. pii: ASN.2019080847. doi: 10.1681/ASN.2019080847. [Epub ahead of print]

PMID:
32165419
2.

CXCR5+PD1+ICOS+ Circulating T Follicular Helpers Are Associated With de novo Donor-Specific Antibodies After Renal Transplantation.

Danger R, Chesneau M, Delbos F, Le Bot S, Kerleau C, Chenouard A, Ville S, Degauque N, Conchon S, Cesbron A, Giral M, Brouard S.

Front Immunol. 2019 Sep 10;10:2071. doi: 10.3389/fimmu.2019.02071. eCollection 2019.

3.

Early Identification of Chronic Lung Allograft Dysfunction: The Need of Biomarkers.

Tissot A, Danger R, Claustre J, Magnan A, Brouard S.

Front Immunol. 2019 Jul 17;10:1681. doi: 10.3389/fimmu.2019.01681. eCollection 2019. Review.

4.

Blood CD9+ B cell, a biomarker of bronchiolitis obliterans syndrome after lung transplantation.

Brosseau C, Danger R, Durand M, Durand E, Foureau A, Lacoste P, Tissot A, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Claustre J, Magnan A, Brouard S; COLT and SysCLAD Consortia.

Am J Transplant. 2019 Nov;19(11):3162-3175. doi: 10.1111/ajt.15532. Epub 2019 Aug 21.

PMID:
31305014
5.

Elicited and pre-existing anti-Neu5Gc antibodies differentially affect human endothelial cells transcriptome.

Le Berre L, Danger R, Mai HL, Amon R, Leviatan Ben-Arye S, Bruneau S, Senage T, Perreault H, Teraiya M, Nguyen TVH, Le Tourneau T, Yu H, Chen X, Galli C, Roussel JC, Manez R, Costa C, Brouard S, Galinanes M, Harris KM, Gitelman S, Cozzi E, Charreau B, Padler-Karavani V, Soulillou JP.

Xenotransplantation. 2019 Nov;26(6):e12535. doi: 10.1111/xen.12535. Epub 2019 Jul 10.

PMID:
31293002
6.

IL-7 receptor influences anti-TNF responsiveness and T cell gut homing in inflammatory bowel disease.

Belarif L, Danger R, Kermarrec L, Nerrière-Daguin V, Pengam S, Durand T, Mary C, Kerdreux E, Gauttier V, Kucik A, Thepenier V, Martin JC, Chang C, Rahman A, Guen NS, Braudeau C, Abidi A, David G, Malard F, Takoudju C, Martinet B, Gérard N, Neveu I, Neunlist M, Coron E, MacDonald TT, Desreumaux P, Mai HL, Le Bas-Bernardet S, Mosnier JF, Merad M, Josien R, Brouard S, Soulillou JP, Blancho G, Bourreille A, Naveilhan P, Vanhove B, Poirier N.

J Clin Invest. 2019 Apr 2;129(5):1910-1925. doi: 10.1172/JCI121668. eCollection 2019 Apr 2.

7.

IL-7 receptor blockade blunts antigen-specific memory T cell responses and chronic inflammation in primates.

Belarif L, Mary C, Jacquemont L, Mai HL, Danger R, Hervouet J, Minault D, Thepenier V, Nerrière-Daguin V, Nguyen E, Pengam S, Largy E, Delobel A, Martinet B, Le Bas-Bernardet S, Brouard S, Soulillou JP, Degauque N, Blancho G, Vanhove B, Poirier N.

Nat Commun. 2018 Oct 26;9(1):4483. doi: 10.1038/s41467-018-06804-y.

8.

[COLT: Ten years of research in lung transplantation, results and perspectives].

Tissot A, Foureau A, Brosseau C, Danger R, Roux A, Bernasconi E, Gomez C, Durand M, Picard BR, Le Pavec J, Claustre J, Lacoste P, Benmerad M, Pain M, Siroux V, Royer PJ, Mordant P, Reynaud-Gaubert M, Kessler R, Brugière O, Mornex JF, Dromer C, Dahan M, Knoop C, Boussaud V, Koutsokera A, Botturi-Cavaillès K, Durand E, Loy J, Nicod L, Pison C, Brouard S, Blanc FX, Magnan A; consortium COLT.

Rev Mal Respir. 2018 Sep;35(7):699-705. doi: 10.1016/j.rmr.2018.06.007. Epub 2018 Aug 9. French. No abstract available.

PMID:
30100530
9.

Molecular Pathways Underlying Adaptive Repair of the Injured Kidney: Novel Donation After Cardiac Death and Acute Kidney Injury Platforms.

Orlando G, Danger R, Okut H, Edgar L, Bussolati B, Gall E, Bergman CR, Tamburrini R, Gazia C, Farney AC, Freedman BI, McPherson G, Rogers J, Stratta RJ, Brouard S, Walker SJ.

Ann Surg. 2020 Feb;271(2):383-390. doi: 10.1097/SLA.0000000000002946.

10.

Corrigendum: Broad Impairment of Natural Killer Cells From Operationally Tolerant Kidney Transplanted Patients.

Dugast E, David G, Oger R, Danger R, Judor JP, Gagne K, Chesneau M, Degauque N, Soulillou JP, Paul P, Picard C, Guerif P, Conchon S, Giral M, Gervois N, Retière C, Brouard S.

Front Immunol. 2018 Mar 26;9:589. doi: 10.3389/fimmu.2018.00589. eCollection 2018.

11.

High circulating CD4+CD25hiFOXP3+ T-cell sub-population early after lung transplantation is associated with development of bronchiolitis obliterans syndrome.

Durand M, Lacoste P, Danger R, Jacquemont L, Brosseau C, Durand E, Tilly G, Loy J, Foureau A, Royer PJ, Tissot A, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Claustre J, Degauque N, Magnan A, Brouard S; COLT and SysCLAD Consortia.

J Heart Lung Transplant. 2018 Jun;37(6):770-781. doi: 10.1016/j.healun.2018.01.1306. Epub 2018 Mar 20.

PMID:
29571601
12.

B cells in operational tolerance.

Chesneau M, Danger R, Soulillou JP, Brouard S.

Hum Immunol. 2018 May;79(5):373-379. doi: 10.1016/j.humimm.2018.02.009. Epub 2018 Feb 16. Review.

PMID:
29458071
13.

Increased degradation of ATP is driven by memory regulatory T cells in kidney transplantation tolerance.

Durand M, Dubois F, Dejou C, Durand E, Danger R, Chesneau M, Brosseau C, Guerif P, Soulillou JP, Degauque N, Eliaou JF, Giral M, Bonnefoy N, Brouard S.

Kidney Int. 2018 May;93(5):1154-1164. doi: 10.1016/j.kint.2017.12.004. Epub 2018 Feb 15.

PMID:
29455908
14.

Blood Gene Expression Predicts Bronchiolitis Obliterans Syndrome.

Danger R, Royer PJ, Reboulleau D, Durand E, Loy J, Tissot A, Lacoste P, Roux A, Reynaud-Gaubert M, Gomez C, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Dahan M, Knoop C, Botturi K, Foureau A, Pison C, Koutsokera A, Nicod LP, Brouard S, Magnan A; COLT and SysCLAD Consortia.

Front Immunol. 2018 Jan 11;8:1841. doi: 10.3389/fimmu.2017.01841. eCollection 2017.

15.

Broad Impairment of Natural Killer Cells from Operationally Tolerant Kidney Transplanted Patients.

Dugast E, David G, Oger R, Danger R, Judor JP, Gagne K, Chesneau M, Degauque N, Soulillou JP, Paul P, Picard C, Guerif P, Conchon S, Giral M, Gervois N, Retière C, Brouard S.

Front Immunol. 2017 Dec 11;8:1721. doi: 10.3389/fimmu.2017.01721. eCollection 2017. Erratum in: Front Immunol. 2018 Mar 26;9:589.

16.

IL-15 Harnesses Pro-inflammatory Function of TEMRA CD8 in Kidney-Transplant Recipients.

Tilly G, Doan-Ngoc TM, Yap M, Caristan A, Jacquemont L, Danger R, Cadoux M, Bruneau S, Giral M, Guerif P, Nicol B, Garcia A, Laplaud DA, Brouard S, Pecqueur Hellman C, Degauque N.

Front Immunol. 2017 Jun 30;8:778. doi: 10.3389/fimmu.2017.00778. eCollection 2017.

17.

IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors.

Whitehouse G, Gray E, Mastoridis S, Merritt E, Kodela E, Yang JHM, Danger R, Mairal M, Christakoudi S, Lozano JJ, Macdougall IC, Tree TIM, Sanchez-Fueyo A, Martinez-Llordella M.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7083-7088. doi: 10.1073/pnas.1620835114. Epub 2017 Jun 5.

18.

A composite score associated with spontaneous operational tolerance in kidney transplant recipients.

Danger R, Chesneau M, Paul C, Guérif P, Durand M, Newell KA, Kanaparthi S, Turka LA, Soulillou JP, Houlgatte R, Giral M, Ramstein G, Brouard S.

Kidney Int. 2017 Jun;91(6):1473-1481. doi: 10.1016/j.kint.2016.12.020. Epub 2017 Feb 24.

19.

T Cells Promote Bronchial Epithelial Cell Secretion of Matrix Metalloproteinase-9 via a C-C Chemokine Receptor Type 2 Pathway: Implications for Chronic Lung Allograft Dysfunction.

Pain M, Royer PJ, Loy J, Girardeau A, Tissot A, Lacoste P, Roux A, Reynaud-Gaubert M, Kessler R, Mussot S, Dromer C, Brugière O, Mornex JF, Guillemain R, Dahan M, Knoop C, Botturi K, Pison C, Danger R, Brouard S, Magnan A; COLT Consortium.

Am J Transplant. 2017 Jun;17(6):1502-1514. doi: 10.1111/ajt.14166. Epub 2017 Jan 23.

20.

Renal Operational Tolerance Is Associated With a Defect of Blood Tfh Cells That Exhibit Impaired B Cell Help.

Chenouard A, Chesneau M, Bui Nguyen L, Le Bot S, Cadoux M, Dugast E, Paul C, Malard-Castagnet S, Ville S, Guérif P, Soulillou JP, Degauque N, Danger R, Giral M, Brouard S.

Am J Transplant. 2017 Jun;17(6):1490-1501. doi: 10.1111/ajt.14142. Epub 2017 Jan 19.

21.

Immune monitoring in renal transplantation: The search for biomarkers.

Danger R, Sawitzki B, Brouard S.

Eur J Immunol. 2016 Dec;46(12):2695-2704. doi: 10.1002/eji.201545963. Review.

22.

Templates as a method for implementing data provenance in decision support systems.

Curcin V, Fairweather E, Danger R, Corrigan D.

J Biomed Inform. 2017 Jan;65:1-21. doi: 10.1016/j.jbi.2016.10.022. Epub 2016 Nov 14.

23.

Hepatic Infiltrates in Operational Tolerant Patients After Liver Transplantation Show Enrichment of Regulatory T Cells Before Proinflammatory Genes Are Downregulated.

Taubert R, Danger R, Londoño MC, Christakoudi S, Martinez-Picola M, Rimola A, Manns MP, Sánchez-Fueyo A, Jaeckel E.

Am J Transplant. 2016 Apr;16(4):1285-93. doi: 10.1111/ajt.13617. Epub 2016 Feb 18.

24.

Deciphering the role of TRIB1 in regulatory T-cells.

Danger R, Dugast E, Braza F, Conchon S, Brouard S.

Biochem Soc Trans. 2015 Oct;43(5):1075-8. doi: 10.1042/BST20150097. Review.

PMID:
26517926
25.

Iron Deficiency Impairs Intra-Hepatic Lymphocyte Mediated Immune Response.

Bonaccorsi-Riani E, Danger R, Lozano JJ, Martinez-Picola M, Kodela E, Mas-Malavila R, Bruguera M, Collins HL, Hider RC, Martinez-Llordella M, Sanchez-Fueyo A.

PLoS One. 2015 Aug 19;10(8):e0136106. doi: 10.1371/journal.pone.0136106. eCollection 2015.

26.

Peripheral phenotype and gene expression profiles of combined liver-kidney transplant patients.

Dumontet E, Danger R, Vagefi PA, Londoño MC, Pallier A, Lozano JJ, Giral M, Degauque N, Soulillou JP, Martínez-Llordella M, Lee H, Latournerie M, Boudjema K, Dulong J, Tarte K, Sanchez-Fueyo A, Feng S, Brouard S, Conchon S.

Liver Int. 2016 Mar;36(3):401-9. doi: 10.1111/liv.12917. Epub 2015 Aug 8.

27.

A methodology for mining clinical data: experiences from TRANSFoRm project.

Danger R, Corrigan D, Soler JK, Kazienko P, Kajdanowicz T, Majeed A, Curcin V.

Stud Health Technol Inform. 2015;210:85-9.

PMID:
25991107
28.

Evidence-based rules from family practice to inform family practice; the learning healthcare system case study on urinary tract infections.

Soler JK, Corrigan D, Kazienko P, Kajdanowicz T, Danger R, Kulisiewicz M, Delaney B.

BMC Fam Pract. 2015 May 16;16:63. doi: 10.1186/s12875-015-0271-4.

29.

Systematic analysis of blood cell transcriptome in end-stage chronic respiratory diseases.

Chesné J, Danger R, Botturi K, Reynaud-Gaubert M, Mussot S, Stern M, Danner-Boucher I, Mornex JF, Pison C, Dromer C, Kessler R, Dahan M, Brugière O, Le Pavec J, Perros F, Humbert M, Gomez C, Brouard S, Magnan A; COLT Consortium.

PLoS One. 2014 Oct 20;9(10):e109291. doi: 10.1371/journal.pone.0109291. eCollection 2014.

30.

MMP-2 as an early synovial biomarker for cranial cruciate ligament disease in dogs.

Boland L, Danger R, Cabon Q, Rabillard M, Brouard S, Bouvy B, Gauthier O.

Vet Comp Orthop Traumatol. 2014;27(3):210-5. doi: 10.3415/VCOT-13-06-0082. Epub 2014 Mar 25.

PMID:
24664192
31.

MicroRNAs, Major Players in B Cells Homeostasis and Function.

Danger R, Braza F, Giral M, Soulillou JP, Brouard S.

Front Immunol. 2014 Mar 11;5:98. doi: 10.3389/fimmu.2014.00098. eCollection 2014. Review.

32.

Expansion of highly differentiated cytotoxic terminally differentiated effector memory CD8+ T cells in a subset of clinically stable kidney transplant recipients: a potential marker for late graft dysfunction.

Yap M, Boeffard F, Clave E, Pallier A, Danger R, Giral M, Dantal J, Foucher Y, Guillot-Gueguen C, Toubert A, Soulillou JP, Brouard S, Degauque N.

J Am Soc Nephrol. 2014 Aug;25(8):1856-68. doi: 10.1681/ASN.2013080848. Epub 2014 Mar 20.

33.

IL-7 receptor blockade following T cell depletion promotes long-term allograft survival.

Mai HL, Boeffard F, Longis J, Danger R, Martinet B, Haspot F, Vanhove B, Brouard S, Soulillou JP.

J Clin Invest. 2014 Apr;124(4):1723-33. doi: 10.1172/JCI66287. Epub 2014 Feb 24.

34.

Unique B cell differentiation profile in tolerant kidney transplant patients.

Chesneau M, Pallier A, Braza F, Lacombe G, Le Gallou S, Baron D, Giral M, Danger R, Guerif P, Aubert-Wastiaux H, Néel A, Michel L, Laplaud DA, Degauque N, Soulillou JP, Tarte K, Brouard S.

Am J Transplant. 2014 Jan;14(1):144-55. doi: 10.1111/ajt.12508. Epub 2013 Nov 13.

35.

Model-based auditability of clinical trial recruitment.

Curcin V, Lim Choi Keung SN, Danger R, Rossiter J, Zhao L, Arvanitis TN.

Stud Health Technol Inform. 2013;192:1223.

PMID:
23920997
36.

Expression of miR-142-5p in peripheral blood mononuclear cells from renal transplant patients with chronic antibody-mediated rejection.

Danger R, Paul C, Giral M, Lavault A, Foucher Y, Degauque N, Pallier A, Durand M, Castagnet S, Duong Van Huyen JP, Delahousse M, Renaudin K, Soulillou JP, Brouard S.

PLoS One. 2013;8(4):e60702. doi: 10.1371/journal.pone.0060702. Epub 2013 Apr 5.

37.

Identification of tribbles-1 as a novel binding partner of Foxp3 in regulatory T cells.

Dugast E, Kiss-Toth E, Docherty L, Danger R, Chesneau M, Pichard V, Judor JP, Pettré S, Conchon S, Soulillou JP, Brouard S, Ashton-Chess J.

J Biol Chem. 2013 Apr 5;288(14):10051-60. doi: 10.1074/jbc.M112.448654. Epub 2013 Feb 15.

38.

Time dependent ROC curves for the estimation of true prognostic capacity of microarray data.

Foucher Y, Danger R.

Stat Appl Genet Mol Biol. 2012 Nov 22;11(6):Article 1. doi: 10.1515/1544-6115.1815.

PMID:
23183763
39.

PARVG gene polymorphism and operational renal allograft tolerance.

Danger R, Thervet E, Grisoni ML, Puig PL, Pallier A, Tregouet D, Lecorre D, Giral M, Legendre C, Soulillou JP, Brouard S.

Transplant Proc. 2012 Nov;44(9):2845-8. doi: 10.1016/j.transproceed.2012.09.034.

PMID:
23146538
40.

The natural history of clinical operational tolerance after kidney transplantation through twenty-seven cases.

Brouard S, Pallier A, Renaudin K, Foucher Y, Danger R, Devys A, Cesbron A, Guillot-Guegen C, Ashton-Chess J, Le Roux S, Harb J, Roussey G, Subra JF, Villemain F, Legendre C, Bemelman FJ, Orlando G, Garnier A, Jambon H, Le Monies De Sagazan H, Braun L, Noël C, Pillebout E, Moal MC, Cantarell C, Hoitsma A, Ranbant M, Testa A, Soulillou JP, Giral M.

Am J Transplant. 2012 Dec;12(12):3296-307. doi: 10.1111/j.1600-6143.2012.04249.x. Epub 2012 Sep 13.

41.

BAFF and BAFF-R levels are associated with risk of long-term kidney graft dysfunction and development of donor-specific antibodies.

Thibault-Espitia A, Foucher Y, Danger R, Migone T, Pallier A, Castagnet S, G-Gueguen C, Devys A, C-Gautier A, Giral M, Soulillou JP, Brouard S.

Am J Transplant. 2012 Oct;12(10):2754-62. doi: 10.1111/j.1600-6143.2012.04194.x. Epub 2012 Aug 6.

42.

A need for biomarkers of operational tolerance in liver and kidney transplantation.

Londoño MC, Danger R, Giral M, Soulillou JP, Sánchez-Fueyo A, Brouard S.

Am J Transplant. 2012 Jun;12(6):1370-7. doi: 10.1111/j.1600-6143.2012.04035.x. Epub 2012 Apr 4. Review.

43.

Upregulation of miR-142-3p in peripheral blood mononuclear cells of operationally tolerant patients with a renal transplant.

Danger R, Pallier A, Giral M, Martínez-Llordella M, Lozano JJ, Degauque N, Sanchez-Fueyo A, Soulillou JP, Brouard S.

J Am Soc Nephrol. 2012 Apr;23(4):597-606. doi: 10.1681/ASN.2011060543. Epub 2012 Jan 26.

44.

SMILE silencing and PMA activation gene networks in HeLa cells: comparison with kidney transplantation gene networks.

Racapé M, Bragazzi N, Sivozhelezov V, Danger R, Pechkova E, Duong Van Huyen JP, Soulillou JP, Brouard S, Nicolini C.

J Cell Biochem. 2012 Jun;113(6):1820-32. doi: 10.1002/jcb.24013.

PMID:
22134986
45.

Matrix metalloproteinase activity in stifle synovial fluid of cranial cruciate ligament deficient dogs and effect of postoperative doxycycline treatment.

Rabillard M, Danger R, Doran IP, Niebauer GW, Brouard S, Gauthier O.

Vet J. 2012 Jul;193(1):271-3. doi: 10.1016/j.tvjl.2011.10.028. Epub 2011 Nov 25.

PMID:
22119570
46.

Comparison of transcriptional and blood cell-phenotypic markers between operationally tolerant liver and kidney recipients.

Lozano JJ, Pallier A, Martinez-Llordella M, Danger R, López M, Giral M, Londoño MC, Rimola A, Soulillou JP, Brouard S, Sánchez-Fueyo A.

Am J Transplant. 2011 Sep;11(9):1916-26. doi: 10.1111/j.1600-6143.2011.03638.x. Epub 2011 Aug 9.

47.

The involvement of SMILE/TMTC3 in endoplasmic reticulum stress response.

Racapé M, Duong Van Huyen JP, Danger R, Giral M, Bleicher F, Foucher Y, Pallier A, Pilet P, Tafelmeyer P, Ashton-Chess J, Dugast E, Pettré S, Charreau B, Soulillou JP, Brouard S.

PLoS One. 2011;6(5):e19321. doi: 10.1371/journal.pone.0019321. Epub 2011 May 16.

48.

A comparison of machine learning techniques for detection of drug target articles.

Danger R, Segura-Bedmar I, Martínez P, Rosso P.

J Biomed Inform. 2010 Dec;43(6):902-13. doi: 10.1016/j.jbi.2010.07.010. Epub 2010 Aug 3.

49.

What can we learn from the transcriptional characterization of spontaneously tolerant transplant recipients?

Danger R, Racapé M, Soulillou JP, Brouard S.

Curr Opin Organ Transplant. 2010 Aug;15(4):435-40. doi: 10.1097/MOT.0b013e32833bfac9.

PMID:
20616726
50.

Patients with drug-free long-term graft function display increased numbers of peripheral B cells with a memory and inhibitory phenotype.

Pallier A, Hillion S, Danger R, Giral M, Racapé M, Degauque N, Dugast E, Ashton-Chess J, Pettré S, Lozano JJ, Bataille R, Devys A, Cesbron-Gautier A, Braudeau C, Larrose C, Soulillou JP, Brouard S.

Kidney Int. 2010 Sep;78(5):503-13. doi: 10.1038/ki.2010.162. Epub 2010 Jun 9.

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