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Items: 1 to 50 of 277

1.

Cancer Metabolism: the Known, Unknowns.

Dang CV.

Biochim Biophys Acta Rev Cancer. 2018 Aug;1870(1):1. doi: 10.1016/j.bbcan.2018.07.006. Epub 2018 Aug 13. No abstract available.

PMID:
30336841
2.

Integrated Analysis of Genetic Ancestry and Genomic Alterations across Cancers.

Yuan J, Hu Z, Mahal BA, Zhao SD, Kensler KH, Pi J, Hu X, Zhang Y, Wang Y, Jiang J, Li C, Zhong X, Montone KT, Guan G, Tanyi JL, Fan Y, Xu X, Morgan MA, Long M, Zhang Y, Zhang R, Sood AK, Rebbeck TR, Dang CV, Zhang L.

Cancer Cell. 2018 Oct 8;34(4):549-560.e9. doi: 10.1016/j.ccell.2018.08.019.

PMID:
30300578
3.

Shedding Light on the Dark Cancer Genomes: Long Noncoding RNAs as Novel Biomarkers and Potential Therapeutic Targets for Cancer.

Zhang L, Peng D, Sood AK, Dang CV, Zhong X.

Mol Cancer Ther. 2018 Sep;17(9):1816-1823. doi: 10.1158/1535-7163.MCT-18-0124. Review.

PMID:
30181330
4.

The Half-Lives of Facts, Paradigm Shifts, and Reproducibility in Cancer Research.

Dang CV.

Cancer Res. 2018 Aug 1;78(15):4105-4106. doi: 10.1158/0008-5472.CAN-18-1751. No abstract available.

PMID:
30068666
5.

Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR.

Walton ZE, Patel CH, Brooks RC, Yu Y, Ibrahim-Hashim A, Riddle M, Porcu A, Jiang T, Ecker BL, Tameire F, Koumenis C, Weeraratna AT, Welsh DK, Gillies R, Alwine JC, Zhang L, Powell JD, Dang CV.

Cell. 2018 Jun 28;174(1):72-87.e32. doi: 10.1016/j.cell.2018.05.009. Epub 2018 May 31.

PMID:
29861175
6.

MYC-induced metabolic stress and tumorigenesis.

Wolpaw AJ, Dang CV.

Biochim Biophys Acta Rev Cancer. 2018 Aug;1870(1):43-50. doi: 10.1016/j.bbcan.2018.05.003. Epub 2018 May 20. Review.

PMID:
29791870
7.

IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers.

Xie H, Tang CH, Song JH, Mancuso A, Del Valle JR, Cao J, Xiang Y, Dang CV, Lan R, Sanchez DJ, Keith B, Hu CC, Simon MC.

J Clin Invest. 2018 Apr 2;128(4):1300-1316. doi: 10.1172/JCI95864. Epub 2018 Feb 26.

8.

Convergence to Cure Cancer through Research: A Message from the New Editor-in-Chief.

Dang CV.

Cancer Res. 2018 Jan 1;78(1):3-4. doi: 10.1158/0008-5472.CAN-17-3771. No abstract available.

PMID:
29298804
9.

A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival.

Bu Y, Yoshida A, Chitnis N, Altman BJ, Tameire F, Oran A, Gennaro V, Armeson KE, McMahon SB, Wertheim GB, Dang CV, Ruggero D, Koumenis C, Fuchs SY, Diehl JA.

Nat Cell Biol. 2018 Jan;20(1):104-115. doi: 10.1038/s41556-017-0006-y. Epub 2017 Dec 11.

10.

Exploiting Metabolic Vulnerabilities of Cancer with Precision and Accuracy.

Wolpaw AJ, Dang CV.

Trends Cell Biol. 2018 Mar;28(3):201-212. doi: 10.1016/j.tcb.2017.11.006. Epub 2017 Dec 8. Review.

PMID:
29229182
11.

Convergence of Cancer Metabolism and Immunity: an Overview.

Dang CV, Kim JW.

Biomol Ther (Seoul). 2018 Jan 1;26(1):4-9. doi: 10.4062/biomolther.2017.194. Review.

12.

Future cancer research priorities in the USA: a Lancet Oncology Commission.

Jaffee EM, Dang CV, Agus DB, Alexander BM, Anderson KC, Ashworth A, Barker AD, Bastani R, Bhatia S, Bluestone JA, Brawley O, Butte AJ, Coit DG, Davidson NE, Davis M, DePinho RA, Diasio RB, Draetta G, Frazier AL, Futreal A, Gambhir SS, Ganz PA, Garraway L, Gerson S, Gupta S, Heath J, Hoffman RI, Hudis C, Hughes-Halbert C, Ibrahim R, Jadvar H, Kavanagh B, Kittles R, Le QT, Lippman SM, Mankoff D, Mardis ER, Mayer DK, McMasters K, Meropol NJ, Mitchell B, Naredi P, Ornish D, Pawlik TM, Peppercorn J, Pomper MG, Raghavan D, Ritchie C, Schwarz SW, Sullivan R, Wahl R, Wolchok JD, Wong SL, Yung A.

Lancet Oncol. 2017 Nov;18(11):e653-e706. doi: 10.1016/S1470-2045(17)30698-8. Epub 2017 Oct 31. Review.

13.

MYC Targeted Long Noncoding RNA DANCR Promotes Cancer in Part by Reducing p21 Levels.

Lu Y, Hu Z, Mangala LS, Stine ZE, Hu X, Jiang D, Xiang Y, Zhang Y, Pradeep S, Rodriguez-Aguayo C, Lopez-Berestein G, DeMarzo AM, Sood AK, Zhang L, Dang CV.

Cancer Res. 2018 Jan 1;78(1):64-74. doi: 10.1158/0008-5472.CAN-17-0815. Epub 2017 Nov 27.

PMID:
29180471
14.

BETting on combination to overcome PARPi resistance.

Zhang Y, Dang CV, Zhang L.

Oncotarget. 2017 Oct 1;8(49):84630-84631. doi: 10.18632/oncotarget.21446. eCollection 2017 Oct 17. No abstract available.

15.

Feeding frenzy for cancer cells.

Dang CV.

Science. 2017 Nov 17;358(6365):862-863. doi: 10.1126/science.aaq1070. No abstract available.

PMID:
29146793
16.

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH).

Rai G, Brimacombe KR, Mott BT, Urban DJ, Hu X, Yang SM, Lee TD, Cheff DM, Kouznetsova J, Benavides GA, Pohida K, Kuenstner EJ, Luci DK, Lukacs CM, Davies DR, Dranow DM, Zhu H, Sulikowski G, Moore WJ, Stott GM, Flint AJ, Hall MD, Darley-Usmar VM, Neckers LM, Dang CV, Waterson AG, Simeonov A, Jadhav A, Maloney DJ.

J Med Chem. 2017 Nov 22;60(22):9184-9204. doi: 10.1021/acs.jmedchem.7b00941. Epub 2017 Nov 9.

17.

The role of long noncoding RNAs in cancer: the dark matter matters.

Hu X, Sood AK, Dang CV, Zhang L.

Curr Opin Genet Dev. 2018 Feb;48:8-15. doi: 10.1016/j.gde.2017.10.004. Epub 2017 Oct 17. Review.

PMID:
29054012
18.

Repression of BET activity sensitizes homologous recombination-proficient cancers to PARP inhibition.

Yang L, Zhang Y, Shan W, Hu Z, Yuan J, Pi J, Wang Y, Fan L, Tang Z, Li C, Hu X, Tanyi JL, Fan Y, Huang Q, Montone K, Dang CV, Zhang L.

Sci Transl Med. 2017 Jul 26;9(400). pii: eaal1645. doi: 10.1126/scitranslmed.aal1645.

19.

From Krebs to clinic: glutamine metabolism to cancer therapy.

Altman BJ, Stine ZE, Dang CV.

Nat Rev Cancer. 2016 Nov;16(11):749. doi: 10.1038/nrc.2016.114. Epub 2016 Oct 14. No abstract available.

PMID:
28704361
20.

From Krebs to clinic: glutamine metabolism to cancer therapy.

Altman BJ, Stine ZE, Dang CV.

Nat Rev Cancer. 2016 Dec;16(12):773. doi: 10.1038/nrc.2016.131. Epub 2016 Nov 11. No abstract available.

PMID:
28704359
21.

MUC-king with HIF May Rewire Pyrimidine Biosynthesis and Curb Gemcitabine Resistance in Pancreatic Cancer.

Dang CV.

Cancer Cell. 2017 Jul 10;32(1):3-5. doi: 10.1016/j.ccell.2017.06.006.

22.

Drugging the 'undruggable' cancer targets.

Dang CV, Reddy EP, Shokat KM, Soucek L.

Nat Rev Cancer. 2017 Aug;17(8):502-508. doi: 10.1038/nrc.2017.36. Epub 2017 Jun 23. Review.

23.

Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin.

Rajeshkumar NV, Yabuuchi S, Pai SG, De Oliveira E, Kamphorst JJ, Rabinowitz JD, Tejero H, Al-Shahrour F, Hidalgo M, Maitra A, Dang CV.

Clin Cancer Res. 2017 Sep 15;23(18):5639-5647. doi: 10.1158/1078-0432.CCR-17-1115. Epub 2017 Jun 13.

24.

c-MYC mRNA tail tale about glutamine control of transcription.

Dang CV.

EMBO J. 2017 Jul 3;36(13):1806-1808. doi: 10.15252/embj.201796999. Epub 2017 May 15. No abstract available.

25.

Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.

Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM.

Cell Metab. 2017 May 2;25(5):1206. doi: 10.1016/j.cmet.2017.04.023. No abstract available.

26.

Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism.

Krishnaiah SY, Wu G, Altman BJ, Growe J, Rhoades SD, Coldren F, Venkataraman A, Olarerin-George AO, Francey LJ, Mukherjee S, Girish S, Selby CP, Cal S, Er U, Sianati B, Sengupta A, Anafi RC, Kavakli IH, Sancar A, Baur JA, Dang CV, Hogenesch JB, Weljie AM.

Cell Metab. 2017 Apr 4;25(4):961-974.e4. doi: 10.1016/j.cmet.2017.03.019. Erratum in: Cell Metab. 2017 May 2;25(5):1206.

27.

Pancreatic Cancer: "A Riddle Wrapped in a Mystery inside an Enigma".

Borazanci E, Dang CV, Robey RW, Bates SE, Chabot JA, Von Hoff DD.

Clin Cancer Res. 2017 Apr 1;23(7):1629-1637. doi: 10.1158/1078-0432.CCR-16-2070. Review.

28.

Correspondence: Oncogenic MYC persistently upregulates the molecular clock component REV-ERBα.

Altman BJ, Hsieh AL, Gouw AM, Dang CV.

Nat Commun. 2017 Mar 23;8:14862. doi: 10.1038/ncomms14862. No abstract available.

29.

A Time for MYC: Metabolism and Therapy.

Dang CV.

Cold Spring Harb Symp Quant Biol. 2016;81:79-83. doi: 10.1101/sqb.2016.81.031153. Epub 2017 Feb 7. Review.

PMID:
28174256
30.

Mixed outcomes for computational predictions.

Dang CV.

Elife. 2017 Jan 19;6. pii: e22661. doi: 10.7554/eLife.22661.

31.

EGF induces epithelial-mesenchymal transition and cancer stem-like cell properties in human oral cancer cells via promoting Warburg effect.

Xu Q, Zhang Q, Ishida Y, Hajjar S, Tang X, Shi H, Dang CV, Le AD.

Oncotarget. 2017 Feb 7;8(6):9557-9571. doi: 10.18632/oncotarget.13771.

32.

Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress.

Huang, Li T, Wang L, Zhang L, Yan R, Li K, Xing S, Wu G, Hu L, Jia W, Lin SC, Dang CV, Song L, Gao P, Zhang H.

Cell Res. 2016 Oct;26(10):1112-1130. doi: 10.1038/cr.2016.109. Epub 2016 Sep 20.

33.

MYC, Metabolic Synthetic Lethality, and Cancer.

Hsieh AL, Dang CV.

Recent Results Cancer Res. 2016;207:73-91. doi: 10.1007/978-3-319-42118-6_4. Review.

PMID:
27557535
34.

From Krebs to clinic: glutamine metabolism to cancer therapy.

Altman BJ, Stine ZE, Dang CV.

Nat Rev Cancer. 2016 Oct;16(10):619-34. doi: 10.1038/nrc.2016.71. Epub 2016 Jul 29. Review. Erratum in: Nat Rev Cancer. 2016 Nov;16(11):749. Nat Rev Cancer. 2016 Dec;16(12 ):773.

35.

Prevalence, antibiotic resistance, and extended-spectrum and AmpC β-lactamase productivity of Salmonella isolates from raw meat and seafood samples in Ho Chi Minh City, Vietnam.

Nguyen DT, Kanki M, Nguyen PD, Le HT, Ngo PT, Tran DN, Le NH, Dang CV, Kawai T, Kawahara R, Yonogi S, Hirai Y, Jinnai M, Yamasaki S, Kumeda Y, Yamamoto Y.

Int J Food Microbiol. 2016 Nov 7;236:115-22. doi: 10.1016/j.ijfoodmicro.2016.07.017. Epub 2016 Jul 14.

PMID:
27479779
36.

Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer.

Zhang Y, He Q, Hu Z, Feng Y, Fan L, Tang Z, Yuan J, Shan W, Li C, Hu X, Tanyi JL, Fan Y, Huang Q, Montone K, Dang CV, Zhang L.

Nat Struct Mol Biol. 2016 Jun;23(6):522-30. doi: 10.1038/nsmb.3211. Epub 2016 Apr 25.

37.

Q-ing tumor glutaminase for therapy.

Stine ZE, Dang CV.

Oncotarget. 2015 Nov 17;6(36):38440-1. doi: 10.18632/oncotarget.6301. No abstract available.

38.

Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers.

Yan X, Hu Z, Feng Y, Hu X, Yuan J, Zhao SD, Zhang Y, Yang L, Shan W, He Q, Fan L, Kandalaft LE, Tanyi JL, Li C, Yuan CX, Zhang D, Yuan H, Hua K, Lu Y, Katsaros D, Huang Q, Montone K, Fan Y, Coukos G, Boyd J, Sood AK, Rebbeck T, Mills GB, Dang CV, Zhang L.

Cancer Cell. 2015 Oct 12;28(4):529-540. doi: 10.1016/j.ccell.2015.09.006.

39.

An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis.

Matkar S, Sharma P, Gao S, Gurung B, Katona BW, Liao J, Muhammad AB, Kong XC, Wang L, Jin G, Dang CV, Hua X.

Cancer Cell. 2015 Oct 12;28(4):472-485. doi: 10.1016/j.ccell.2015.09.005.

40.

Splicing and Dicing MYC-Mediated Synthetic Lethality.

Stine ZE, Dang CV.

Cancer Cell. 2015 Oct 12;28(4):405-406. doi: 10.1016/j.ccell.2015.09.016.

41.

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells.

Altman BJ, Hsieh AL, Sengupta A, Krishnanaiah SY, Stine ZE, Walton ZE, Gouw AM, Venkataraman A, Li B, Goraksha-Hicks P, Diskin SJ, Bellovin DI, Simon MC, Rathmell JC, Lazar MA, Maris JM, Felsher DW, Hogenesch JB, Weljie AM, Dang CV.

Cell Metab. 2015 Dec 1;22(6):1009-19. doi: 10.1016/j.cmet.2015.09.003. Epub 2015 Sep 17.

42.

MYC, Metabolism, and Cancer.

Stine ZE, Walton ZE, Altman BJ, Hsieh AL, Dang CV.

Cancer Discov. 2015 Oct;5(10):1024-39. doi: 10.1158/2159-8290.CD-15-0507. Epub 2015 Sep 17. Review.

43.

Turning publicly available gene expression data into discoveries using gene set context analysis.

Ji Z, Vokes SA, Dang CV, Ji H.

Nucleic Acids Res. 2016 Jan 8;44(1):e8. doi: 10.1093/nar/gkv873. Epub 2015 Sep 8.

44.

MYC and metabolism on the path to cancer.

Hsieh AL, Walton ZE, Altman BJ, Stine ZE, Dang CV.

Semin Cell Dev Biol. 2015 Jul;43:11-21. doi: 10.1016/j.semcdb.2015.08.003. Epub 2015 Aug 12. Review.

45.

The Ketogenic Diet Does Not Affect Growth of Hedgehog Pathway Medulloblastoma in Mice.

Dang MT, Wehrli S, Dang CV, Curran T.

PLoS One. 2015 Jul 20;10(7):e0133633. doi: 10.1371/journal.pone.0133633. eCollection 2015.

46.

Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function.

Rajeshkumar NV, Dutta P, Yabuuchi S, de Wilde RF, Martinez GV, Le A, Kamphorst JJ, Rabinowitz JD, Jain SK, Hidalgo M, Dang CV, Gillies RJ, Maitra A.

Cancer Res. 2015 Aug 15;75(16):3355-64. doi: 10.1158/0008-5472.CAN-15-0108. Epub 2015 Jun 25.

47.

A metabolic perspective of Peto's paradox and cancer.

Dang CV.

Philos Trans R Soc Lond B Biol Sci. 2015 Jul 19;370(1673). pii: 20140223. doi: 10.1098/rstb.2014.0223. Review.

48.

MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism.

Shroff EH, Eberlin LS, Dang VM, Gouw AM, Gabay M, Adam SJ, Bellovin DI, Tran PT, Philbrick WM, Garcia-Ocana A, Casey SC, Li Y, Dang CV, Zare RN, Felsher DW.

Proc Natl Acad Sci U S A. 2015 May 26;112(21):6539-44. doi: 10.1073/pnas.1507228112. Epub 2015 May 11.

49.

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis.

Xiang Y, Stine ZE, Xia J, Lu Y, O'Connor RS, Altman BJ, Hsieh AL, Gouw AM, Thomas AG, Gao P, Sun L, Song L, Yan B, Slusher BS, Zhuo J, Ooi LL, Lee CG, Mancuso A, McCallion AS, Le A, Milone MC, Rayport S, Felsher DW, Dang CV.

J Clin Invest. 2015 Jun;125(6):2293-306. doi: 10.1172/JCI75836. Epub 2015 Apr 27.

50.

Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate.

Korangath P, Teo WW, Sadik H, Han L, Mori N, Huijts CM, Wildes F, Bharti S, Zhang Z, Santa-Maria CA, Tsai H, Dang CV, Stearns V, Bhujwalla ZM, Sukumar S.

Clin Cancer Res. 2015 Jul 15;21(14):3263-73. doi: 10.1158/1078-0432.CCR-14-1200. Epub 2015 Mar 26.

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