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Items: 1 to 50 of 189

1.

Multiparametric liquid biopsy analysis in metastatic prostate cancer.

Hodara E, Morrison G, Cunha A, Zainfeld D, Xu T, Xu Y, Dempsey PW, Pagano PC, Bischoff F, Khurana A, Koo S, Ting M, Cotter PD, Moore MW, Gunn S, Usher J, Rabizadeh S, Danenberg P, Danenberg K, Carpten J, Dorff T, Quinn D, Goldkorn A.

JCI Insight. 2019 Mar 7;4(5). pii: 125529. doi: 10.1172/jci.insight.125529. eCollection 2019 Mar 7.

2.

Frequencies and expression levels of programmed death ligand 1 (PD-L1) in circulating tumor RNA (ctRNA) in various cancer types.

Ishiba T, Hoffmann AC, Usher J, Elshimali Y, Sturdevant T, Dang M, Jaimes Y, Tyagi R, Gonzales R, Grino M, Pinski JK, Barzi A, Raez LE, Eberhardt WE, Theegarten D, Lenz HJ, Uetake H, Danenberg PV, Danenberg K.

Biochem Biophys Res Commun. 2018 Jun 7;500(3):621-625. doi: 10.1016/j.bbrc.2018.04.120. Epub 2018 Apr 30.

PMID:
29679564
3.

Epidermal Growth Factor Receptor, Excision-Repair Cross-Complementation Group 1 Protein, and Thymidylate Synthase Expression in Penile Cancer.

Dorff TB, Schuckman AK, Schwartz R, Rashad S, Bulbul A, Cai J, Pinski J, Ma Y, Danenberg K, Skinner E, Quinn DI.

Clin Genitourin Cancer. 2016 Oct;14(5):450-456.e1. doi: 10.1016/j.clgc.2016.01.013. Epub 2016 Feb 6.

PMID:
26935231
4.

Efficiency of fluorodeoxyglucose positron emission tomography/computed tomography to predict prognosis in breast cancer patients received neoadjuvant chemotherapy.

Ishiba T, Nakagawa T, Sato T, Nagahara M, Oda G, Sugimoto H, Kasahara M, Hosoya T, Kubota K, Fujioka T, Danenberg P, Danenberg K, Uetake H.

Springerplus. 2015 Dec 24;4:817. doi: 10.1186/s40064-015-1634-y. eCollection 2015.

5.

Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation.

Bohanes P, Rankin CJ, Blanke CD, Winder T, Ulrich CM, Smalley SR, Rich TA, Martensen JA, Benson AB 3rd, Mayer RJ, Cripps CM, Danenberg K, Makar KW, Zhang W, Benedetti JK, Lenz HJ.

Clin Cancer Res. 2015 Apr 1;21(7):1583-90. doi: 10.1158/1078-0432.CCR-14-0857. Epub 2015 Jan 14.

6.

Large-scale screening and molecular characterization of EML4-ALK fusion variants in archival non-small-cell lung cancer tumor specimens using quantitative reverse transcription polymerase chain reaction assays.

Li T, Maus MK, Desai SJ, Beckett LA, Stephens C, Huang E, Hsiang J, Zeger G, Danenberg KD, Astrow SH, Gandara DR.

J Thorac Oncol. 2014 Jan;9(1):18-25. doi: 10.1097/JTO.0000000000000030.

7.

KRAS mutations in non-small-cell lung cancer and colorectal cancer: implications for EGFR-targeted therapies.

Maus MK, Grimminger PP, Mack PC, Astrow SH, Stephens C, Zeger G, Hsiang J, Brabender J, Friedrich M, Alakus H, Hölscher AH, Lara P, Danenberg KD, Lenz HJ, Gandara DR.

Lung Cancer. 2014 Feb;83(2):163-7. doi: 10.1016/j.lungcan.2013.11.010. Epub 2013 Nov 21.

PMID:
24331409
8.

Epidermal growth factor receptor-targeted therapy in squamous cell carcinoma of the penis: a report of 3 cases.

Brown A, Ma Y, Danenberg K, Schuckman AK, Pinski JK, Pagliaro LC, Quinn DI, Dorff TB.

Urology. 2014 Jan;83(1):159-65. doi: 10.1016/j.urology.2013.08.074. Epub 2013 Nov 12. Erratum in: Urology. 2014 Jun;83(6):1446.

PMID:
24238569
9.

Regulation of MLH1 mRNA and protein expression by promoter methylation in primary colorectal cancer: a descriptive and prognostic cancer marker study.

Jensen LH, Rasmussen AA, Byriel L, Kuramochi H, Crüger DG, Lindebjerg J, Danenberg PV, Jakobsen A, Danenberg K.

Cell Oncol (Dordr). 2013 Oct;36(5):411-9. doi: 10.1007/s13402-013-0148-2. Epub 2013 Sep 12.

PMID:
24027018
10.

Histology-related associations of ERCC1, RRM1, and TS biomarkers in patients with non-small-cell lung cancer: implications for therapy.

Maus MK, Mack PC, Astrow SH, Stephens CL, Zeger GD, Grimminger PP, Hsiang JH, Huang E, Li T, Lara PN, Danenberg KD, Gandara DR.

J Thorac Oncol. 2013 May;8(5):582-6. doi: 10.1097/JTO.0b013e318287c3c5.

11.

Intratumoral expression profiling of genes involved in angiogenesis in colorectal cancer patients treated with chemotherapy plus the VEGFR inhibitor PTK787/ZK 222584 (vatalanib).

Wilson PM, Yang D, Azuma M, Shi MM, Danenberg KD, Lebwohl D, Sherrod A, Ladner RD, Zhang W, Danenberg PV, Trarbach T, Folprecht G, Meinhardt G, Lenz HJ.

Pharmacogenomics J. 2013 Oct;13(5):410-6. doi: 10.1038/tpj.2012.23. Epub 2012 Jun 5.

PMID:
22664478
12.

Pharmacogenetic profiling of CD133 is associated with response rate (RR) and progression-free survival (PFS) in patients with metastatic colorectal cancer (mCRC), treated with bevacizumab-based chemotherapy.

Pohl A, El-Khoueiry A, Yang D, Zhang W, Lurje G, Ning Y, Winder T, Hu-Lieskoven S, Iqbal S, Danenberg KD, Kahn M, Teo JL, Shriki J, Stebbing J, Lenz HJ.

Pharmacogenomics J. 2013 Apr;13(2):173-80. doi: 10.1038/tpj.2011.61. Epub 2012 Jan 10.

13.

Response prediction in metastasised colorectal cancer using intratumoural thymidylate synthase: results of a randomised multicentre trial.

Kornmann M, Hebart H, Danenberg K, Goeb R, Staib L, Kron M, Henne-Bruns D, Danenberg P, Link KH.

Eur J Cancer. 2012 Jul;48(10):1443-51. doi: 10.1016/j.ejca.2011.11.007. Epub 2011 Nov 29.

PMID:
22133572
14.

S0356: a phase II clinical and prospective molecular trial with oxaliplatin, fluorouracil, and external-beam radiation therapy before surgery for patients with esophageal adenocarcinoma.

Leichman LP, Goldman BH, Bohanes PO, Lenz HJ, Thomas CR, Billingsley KG, Corless CL, Iqbal S, Gold PJ, Benedetti JK, Danenberg KD, Blanke CD.

J Clin Oncol. 2011 Dec 1;29(34):4555-60. doi: 10.1200/JCO.2011.36.7490. Epub 2011 Oct 24.

15.

TS and ERCC-1 mRNA expressions and clinical outcome in patients with metastatic colon cancer in CONFIRM-1 and -2 clinical trials.

Grimminger PP, Shi M, Barrett C, Lebwohl D, Danenberg KD, Brabender J, Vigen CL, Danenberg PV, Winder T, Lenz HJ.

Pharmacogenomics J. 2012 Oct;12(5):404-11. doi: 10.1038/tpj.2011.29. Epub 2011 Jul 26.

PMID:
21788964
16.

Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients.

Xie Y, Xiao G, Coombes KR, Behrens C, Solis LM, Raso G, Girard L, Erickson HS, Roth J, Heymach JV, Moran C, Danenberg K, Minna JD, Wistuba II.

Clin Cancer Res. 2011 Sep 1;17(17):5705-14. doi: 10.1158/1078-0432.CCR-11-0196. Epub 2011 Jul 8.

17.

Gene expression of the mismatch repair gene MSH2 in primary colorectal cancer.

Jensen LH, Kuramochi H, Crüger DG, Lindebjerg J, Kolvraa S, Danenberg P, Danenberg K, Jakobsen A.

Tumour Biol. 2011 Oct;32(5):977-83. doi: 10.1007/s13277-011-0199-9. Epub 2011 Jul 6.

PMID:
21732224
18.

Biomarkers for cetuximab-based neoadjuvant radiochemotherapy in locally advanced rectal cancer.

Grimminger PP, Danenberg P, Dellas K, Arnold D, Rödel C, Machiels JP, Haustermans K, Debucquoy A, Velenik V, Sempoux C, Bracko M, Hölscher AH, Semrau R, Yang D, Danenberg K, Lenz HJ, Vallböhmer D.

Clin Cancer Res. 2011 May 15;17(10):3469-77. doi: 10.1158/1078-0432.CCR-10-2273. Epub 2011 May 10.

19.

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy.

Collisson EA, Sadanandam A, Olson P, Gibb WJ, Truitt M, Gu S, Cooc J, Weinkle J, Kim GE, Jakkula L, Feiler HS, Ko AH, Olshen AB, Danenberg KL, Tempero MA, Spellman PT, Hanahan D, Gray JW.

Nat Med. 2011 Apr;17(4):500-3. doi: 10.1038/nm.2344. Epub 2011 Apr 3.

20.

Southwest Oncology Group study S0413: a phase II trial of lapatinib (GW572016) as first-line therapy in patients with advanced or metastatic gastric cancer.

Iqbal S, Goldman B, Fenoglio-Preiser CM, Lenz HJ, Zhang W, Danenberg KD, Shibata SI, Blanke CD.

Ann Oncol. 2011 Dec;22(12):2610-5. doi: 10.1093/annonc/mdr021. Epub 2011 Mar 17.

21.

The gene expression profile of cardia intestinal metaplasia is similar to that of Barrett's esophagus, not gastric intestinal metaplasia.

Oh DS, DeMeester SR, Tanaka K, Marjoram P, Kuramochi H, Vallbohmer D, Danenberg K, Chandrasoma PT, DeMeester TR, Hagen JA.

Dis Esophagus. 2011 Sep;24(7):516-22. doi: 10.1111/j.1442-2050.2010.01176.x. Epub 2011 Feb 10.

PMID:
21309924
22.

A microdosing approach for characterizing formation and repair of carboplatin-DNA monoadducts and chemoresistance.

Henderson PT, Li T, He M, Zhang H, Malfatti M, Gandara D, Grimminger PP, Danenberg KD, Beckett L, de Vere White RW, Turteltaub KW, Pan CX.

Int J Cancer. 2011 Sep 15;129(6):1425-34. doi: 10.1002/ijc.25814. Epub 2011 Mar 4.

23.

Molecular predictors of combination targeted therapies (cetuximab, bevacizumab) in irinotecan-refractory colorectal cancer (BOND-2 study).

Zhang W, Azuma M, Lurje G, Gordon MA, Yang D, Pohl A, Ning Y, Bohanes P, Gerger A, Winder T, Hollywood E, Danenberg KD, Saltz L, Lenz HJ.

Anticancer Res. 2010 Oct;30(10):4209-17.

PMID:
21036743
24.

Association of epidermal growth factor receptor activating mutations with low ERCC1 gene expression in non-small cell lung cancer.

Gandara DR, Grimminger P, Mack PC, Lara PN Jr, Li T, Danenberg PV, Danenberg KD.

J Thorac Oncol. 2010 Dec;5(12):1933-8. doi: 10.1097/JTO.0b013e3181fd418d.

25.

MDR1 and ERCC1 expression predict outcome of patients with locally advanced bladder cancer receiving adjuvant chemotherapy.

Hoffmann AC, Wild P, Leicht C, Bertz S, Danenberg KD, Danenberg PV, Stöhr R, Stöckle M, Lehmann J, Schuler M, Hartmann A.

Neoplasia. 2010 Aug;12(8):628-36.

26.

The relationship between proangiogenic gene expression levels in prostate cancer and their prognostic value for clinical outcomes.

Mori R, Dorff TB, Xiong S, Tarabolous CJ, Ye W, Groshen S, Danenberg KD, Danenberg PV, Pinski JK.

Prostate. 2010 Nov 1;70(15):1692-700. doi: 10.1002/pros.21204.

PMID:
20564320
27.

Pharmacogenetic profiling of Aurora kinase B is associated with overall survival in metastatic colorectal cancer.

Pohl A, Azuma M, Zhang W, Yang D, Ning Y, Winder T, Danenberg K, Lenz HJ.

Pharmacogenomics J. 2011 Apr;11(2):93-9. doi: 10.1038/tpj.2010.18. Epub 2010 Apr 6.

PMID:
20368716
28.

Ornithine decarboxylase mRNA expression in curatively resected non-small-cell lung cancer.

Grimminger PP, Schneider PM, Metzger R, Vallböhmer D, Danenberg KD, Danenberg PV, Hölscher AH, Brabender J.

Clin Lung Cancer. 2010 Mar 1;11(2):114-9. doi: 10.3816/CLC.2010.n.015.

PMID:
20199977
29.

The prognostic role of Bcl-2 mRNA expression in curatively resected non-small cell lung cancer (NSCLC).

Grimminger PP, Schneider PM, Metzger R, Vallböhmer D, Danenberg KD, Danenberg PV, Hölscher AH, Brabender J.

Lung Cancer. 2010 Oct;70(1):82-7. doi: 10.1016/j.lungcan.2009.12.013. Epub 2010 Jan 12.

PMID:
20064672
30.

A phase I/II trial of vorinostat in combination with 5-fluorouracil in patients with metastatic colorectal cancer who previously failed 5-FU-based chemotherapy.

Wilson PM, El-Khoueiry A, Iqbal S, Fazzone W, LaBonte MJ, Groshen S, Yang D, Danenberg KD, Cole S, Kornacki M, Ladner RD, Lenz HJ.

Cancer Chemother Pharmacol. 2010 Apr;65(5):979-88. doi: 10.1007/s00280-009-1236-x.

PMID:
20062993
31.

Epidermal growth factor receptor (EGFR) mRNA levels and protein expression levels in primary colorectal cancer and corresponding liver metastases.

Kuramochi H, Hayashi K, Nakajima G, Kamikozuru H, Yamamoto M, Danenberg KD, Danenberg PV.

Cancer Chemother Pharmacol. 2010 Apr;65(5):825-31. doi: 10.1007/s00280-009-1087-5. Epub 2009 Aug 22.

PMID:
19701635
32.

A three-gene signature for outcome in soft tissue sarcoma.

Hoffmann AC, Danenberg KD, Taubert H, Danenberg PV, Wuerl P.

Clin Cancer Res. 2009 Aug 15;15(16):5191-8. doi: 10.1158/1078-0432.CCR-08-2534. Epub 2009 Aug 11. Erratum in: Clin Cancer Res. 2009 Oct;15(20):6472. Hoffman, Andreas-Claudius [corrected to Hoffmann, Andreas-Claudius].

33.

Loss of heterozygosity at thymidylate synthase locus in Barrett's metaplasia, dysplasia, and carcinoma sequences.

Kuramochi H, Uchida K, Peters JH, Shimizu D, Vallbohmer D, Schneider S, Danenberg KD, Danenberg PV.

BMC Cancer. 2009 May 21;9:157. doi: 10.1186/1471-2407-9-157.

34.

Messenger RNA expression of COX-2 and angiogenic factors in primary colorectal cancer and corresponding liver metastasis.

Kobayashi H, Sugihara K, Uetake H, Higuchi T, Yasuno M, Enomoto M, Iida S, Lenz HJ, Danenberg KD, Danenberg PV.

Int J Oncol. 2009 Apr;34(4):1147-53.

PMID:
19287974
36.

Alterations of p16 and p14ARF genes and their 9p21 locus in oral squamous cell carcinoma.

Ohta S, Uemura H, Matsui Y, Ishiguro H, Fujinami K, Kondo K, Miyamoto H, Yazawa T, Danenberg K, Danenberg PV, Tohnai I, Kubota Y.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Jan;107(1):81-91. doi: 10.1016/j.tripleo.2008.08.027.

PMID:
19101490
37.

Tissue handling and specimen preparation in surgical pathology: issues concerning the recovery of nucleic acids from formalin-fixed, paraffin-embedded tissue.

Hewitt SM, Lewis FA, Cao Y, Conrad RC, Cronin M, Danenberg KD, Goralski TJ, Langmore JP, Raja RG, Williams PM, Palma JF, Warrington JA.

Arch Pathol Lab Med. 2008 Dec;132(12):1929-35. doi: 10.1043/1543-2165-132.12.1929. Review.

PMID:
19061293
38.

HER-2 gene amplification, HER-2 and epidermal growth factor receptor mRNA and protein expression, and lapatinib efficacy in women with metastatic breast cancer.

Press MF, Finn RS, Cameron D, Di Leo A, Geyer CE, Villalobos IE, Santiago A, Guzman R, Gasparyan A, Ma Y, Danenberg K, Martin AM, Williams L, Oliva C, Stein S, Gagnon R, Arbushites M, Koehler MT.

Clin Cancer Res. 2008 Dec 1;14(23):7861-70. doi: 10.1158/1078-0432.CCR-08-1056.

39.
40.

Messenger RNA expression of TS and ERCC1 in colorectal cancer and matched liver metastasis.

Kobayashi H, Sugihara K, Uetake H, Higuchi T, Yasuno M, Enomoto M, Iida S, Azuma M, Mori R, Omori A, Lenz HJ, Danenberg KD, Danenberg PV.

Int J Oncol. 2008 Dec;33(6):1257-62.

PMID:
19020759
41.

Gene profiling and pathway analysis of neuroendocrine transdifferentiated prostate cancer cells.

Mori R, Xiong S, Wang Q, Tarabolous C, Shimada H, Panteris E, Danenberg KD, Danenberg PV, Pinski JK.

Prostate. 2009 Jan 1;69(1):12-23. doi: 10.1002/pros.20851.

PMID:
18814146
42.

Validation of a rodent model of Barrett's esophagus using quantitative gene expression profiling.

Oh DS, DeMeester SR, Dunst CM, Mori R, Lehman BJ, Kuramochi H, Danenberg K, Danenberg P, Hagen JA, Chandrasoma P, DeMeester TR.

Surg Endosc. 2009 Jun;23(6):1346-52. doi: 10.1007/s00464-008-0169-5. Epub 2008 Sep 24.

PMID:
18813976
43.

High expression of heparanase is significantly associated with dedifferentiation and lymph node metastasis in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA and via HIF1a to HB-EGF and bFGF.

Hoffmann AC, Mori R, Vallbohmer D, Brabender J, Drebber U, Baldus SE, Klein E, Azuma M, Metzger R, Hoffmann C, Hoelscher AH, Danenberg KD, Prenzel KL, Danenberg PV.

J Gastrointest Surg. 2008 Oct;12(10):1674-81; discussion 1681-2. doi: 10.1007/s11605-008-0628-2. Epub 2008 Aug 13.

PMID:
18704599
44.

Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer.

Makino H, Uetake H, Danenberg K, Danenberg PV, Sugihara K.

BMC Cancer. 2008 Jul 25;8:210. doi: 10.1186/1471-2407-8-210.

45.

Both beta-actin and GAPDH are useful reference genes for normalization of quantitative RT-PCR in human FFPE tissue samples of prostate cancer.

Mori R, Wang Q, Danenberg KD, Pinski JK, Danenberg PV.

Prostate. 2008 Oct 1;68(14):1555-60. doi: 10.1002/pros.20815.

PMID:
18651557
46.

Molecular profiling including epidermal growth factor receptor and p21 expression in high-risk breast cancer patients as indicators of outcome.

Somlo G, Chu P, Frankel P, Ye W, Groshen S, Doroshow JH, Danenberg K, Danenberg P.

Ann Oncol. 2008 Nov;19(11):1853-9. doi: 10.1093/annonc/mdn402. Epub 2008 Jul 17.

47.

High expression of HIF1a is a predictor of clinical outcome in patients with pancreatic ductal adenocarcinomas and correlated to PDGFA, VEGF, and bFGF.

Hoffmann AC, Mori R, Vallbohmer D, Brabender J, Klein E, Drebber U, Baldus SE, Cooc J, Azuma M, Metzger R, Hoelscher AH, Danenberg KD, Prenzel KL, Danenberg PV.

Neoplasia. 2008 Jul;10(7):674-9.

48.

Plasma DNA is more reliable than carcinoembryonic antigen for diagnosis of recurrent esophageal cancer.

Banki F, Yacoub WN, Hagen JA, Mason RJ, Ayazi S, DeMeester SR, Lipham JC, Danenberg K, Danenberg P, DeMeester TR.

J Am Coll Surg. 2008 Jul;207(1):30-5. doi: 10.1016/j.jamcollsurg.2008.01.004. Epub 2008 Apr 14.

PMID:
18589358
49.

Predictors of response and survival for neoadjuvant treated patients with esophageal adenocarcinoma.

Theisen J, Danenberg K, Ott K, Becker K, Danenberg P, Stein HJ, Siewert JR.

Dis Esophagus. 2008;21(7):601-6. doi: 10.1111/j.1442-2050.2008.00820.x. Epub 2008 Apr 22.

PMID:
18430179
50.

Adenocarcinoma developing in de novo Barrett's mucosa in the remnant esophagus after esophagectomy: clinical and molecular assessment.

Gutschow CA, Vallböhmer D, Stolte M, Oh D, Danenberg K, Danenberg P, Schneider PM, Hölscher AH.

Dis Esophagus. 2008;21(3):E6-8. doi: 10.1111/j.1442-2050.2007.00784.x.

PMID:
18430096

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