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The culture of follow up blood cultures.

Wiggers JB, Daneman N.

Clin Microbiol Infect. 2020 Mar 14. pii: S1198-743X(20)30145-2. doi: 10.1016/j.cmi.2020.03.003. [Epub ahead of print] No abstract available.


Using Genetic Distance from Archived Samples for the Prediction of Antibiotic Resistance in Escherichia coli.

MacFadden DR, Coburn B, Břinda K, Corbeil A, Daneman N, Fisman D, Lee RS, Lipsitch M, McGeer A, Melano RG, Mubareka S, Hanage WP.

Antimicrob Agents Chemother. 2020 Mar 9. pii: AAC.02417-19. doi: 10.1128/AAC.02417-19. [Epub ahead of print]


Antibiotic prescribing choices and their comparative C. difficile infection risks: a longitudinal case-cohort study.

Brown KA, Langford B, Schwartz KL, Diong C, Garber G, Daneman N.

Clin Infect Dis. 2020 Feb 18. pii: ciaa124. doi: 10.1093/cid/ciaa124. [Epub ahead of print]


A pilot randomized controlled trial of 7 versus 14 days of antibiotic treatment for bloodstream infection on non-intensive care versus intensive care wards.

Daneman N, Rishu AH, Pinto R, Arabi Y, Belley-Cote EP, Cirone R, Downing M, Cook DJ, Hall R, McGuinness S, McIntyre L, Muscedere J, Parke R, Reynolds S, Rogers BA, Shehabi Y, Shin P, Whitlock R, Fowler RA; Canadian Critical Care Trials Group.

Trials. 2020 Jan 15;21(1):92. doi: 10.1186/s13063-019-4033-9.


Comparative Effectiveness Of Fluoroquinolone Antibiotic Use In Uncomplicated Acute Exacerbations Of COPD: A Multi-Cohort Study.

Ernst P, Dahl M, Chateau D, Daneman N, Quail J, Sketris IS, Fisher A, Zhang J, Bugden S; Canadian Network for Observational Drug Effect Studies (CNODES) Investigators.

Int J Chron Obstruct Pulmon Dis. 2019 Dec 18;14:2939-2946. doi: 10.2147/COPD.S226324. eCollection 2019.


Interfacility patient sharing and Clostridioides difficile infection incidence in the Ontario hospital system: A 13-year cohort study.

Brown KA, McGeer A, Schwartz KL, Diong C, Etches J, Garber G, Johnstone J, Langford B, Daneman N.

Infect Control Hosp Epidemiol. 2020 Feb;41(2):154-160. doi: 10.1017/ice.2019.283.


Predictors of Treatment Failure for Hip and Knee Prosthetic Joint Infections in the Setting of 1- and 2-Stage Exchange Arthroplasty: A Multicenter Retrospective Cohort.

Kandel CE, Jenkinson R, Daneman N, Backstein D, Hansen BE, Muller MP, Katz KC, Widdifield J, Bogoch E, Ward S, Sajja A, Jeldes FG, McGeer A.

Open Forum Infect Dis. 2019 Oct 21;6(11):ofz452. doi: 10.1093/ofid/ofz452. eCollection 2019 Nov.


Fluoroquinolone use for uncomplicated urinary tract infections in women: a retrospective cohort study.

Daneman N, Chateau D, Dahl M, Zhang J, Fisher A, Sketris IS, Quail J, Marra F, Ernst P, Bugden S; Canadian Network for Observational Drug Effect Studies (CNODES) Investigators.

Clin Microbiol Infect. 2019 Oct 23. pii: S1198-743X(19)30552-X. doi: 10.1016/j.cmi.2019.10.016. [Epub ahead of print]


Association between Physician Intensity of Antibiotic Prescribing and the Prescription of Benzodiazepines, Opioids and Proton-Pump Inhibitors to Nursing Home Residents: a Population-Based Observational Study.

Quinn KL, Campitelli MA, Diong C, Daneman N, Stall NM, Morris AM, Detsky AS, Jeffs L, Maxwell CJ, Bell CM, Bronskill SE.

J Gen Intern Med. 2019 Dec;34(12):2763-2771. doi: 10.1007/s11606-019-05333-8. Epub 2019 Oct 1.


Validating a popular outpatient antibiotic database to reliably identify high prescribing physicians for patients 65 years of age and older.

Schwartz KL, Chen C, Langford BJ, Brown KA, Daneman N, Johnstone J, Wu JH, Leung V, Garber G.

PLoS One. 2019 Sep 26;14(9):e0223097. doi: 10.1371/journal.pone.0223097. eCollection 2019.


Incidence of Hospitalizations and Emergency Department Visits for Herpes Zoster in Immunocompromised and Immunocompetent Adults in Ontario, Canada, 2002-2016.

Buchan SA, Daneman N, Wang J, Garber G, Wormsbecker AE, Wilson SE, Deeks SL.

Clin Infect Dis. 2019 Aug 22. pii: ciz769. doi: 10.1093/cid/ciz769. [Epub ahead of print]


Influencing duration of antibiotic therapy: A behavior change analysis in long-term care.

Langford BJ, Quirk J, Carey S, Daneman N, Garber GE.

Am J Infect Control. 2019 Dec;47(12):1409-1414. doi: 10.1016/j.ajic.2019.05.020. Epub 2019 Jul 18.


The Urine Culturing Cascade: Variation in Nursing Home Urine Culturing and Association with Antibiotic Use and C. difficile infection.

Brown KA, Daneman N, Schwartz KL, Langford B, McGeer A, Quirk J, Diong C, Garber G.

Clin Infect Dis. 2019 Jun 14. pii: ciz482. doi: 10.1093/cid/ciz482. [Epub ahead of print]


Headache and vision changes in an elderly man with rheumatoid arthritis.

Kwok TSH, Daneman N, Lake SL.

Int J Rheum Dis. 2019 Jul;22(7):1331-1334. doi: 10.1111/1756-185X.13589. Epub 2019 May 22.


Duration of therapy recommended for bacteraemic illness varies widely amongst clinicians.

Alwan M, Davis JS, Daneman N, Fowler R, Shehabi Y, Rogers B.

Int J Antimicrob Agents. 2019 Aug;54(2):184-188. doi: 10.1016/j.ijantimicag.2019.05.011. Epub 2019 May 11.


Predictive utility of swab screening for extended-spectrum beta-lactamase-producing organisms in selection of empiric antibiotics for Gram-negative sterile-site infections: A retrospective cohort study.

Brasg IA, Elligsen M, Daneman N, MacFadden DR.

Infect Control Hosp Epidemiol. 2019 Jul;40(7):823-824. doi: 10.1017/ice.2019.96. Epub 2019 Apr 29. No abstract available.


Time-sensitive predictors of embolism in patients with left-sided endocarditis: Cohort study.

Yang A, Tan C, Adhikari NKJ, Daneman N, Pinto R, Haynen BKM, Cohen G, Hansen MS.

PLoS One. 2019 Apr 25;14(4):e0215924. doi: 10.1371/journal.pone.0215924. eCollection 2019.


Predictors and variability of antibiotic prescribing amongst family physicians.

Schwartz KL, Brown KA, Etches J, Langford BJ, Daneman N, Tu K, Johnstone J, Achonu C, Garber G.

J Antimicrob Chemother. 2019 Jul 1;74(7):2098-2105. doi: 10.1093/jac/dkz112.


A Retrospective Forensic Review of Unexpected Infectious Deaths.

Sehgal P, Pollanen M, Daneman N.

Open Forum Infect Dis. 2019 Feb 15;6(4):ofz081. doi: 10.1093/ofid/ofz081. eCollection 2019 Apr.


Comparing Patient Risk Factor-, Sequence Type-, and Resistance Locus Identification-Based Approaches for Predicting Antibiotic Resistance in Escherichia coli Bloodstream Infections.

MacFadden DR, Melano RG, Coburn B, Tijet N, Hanage WP, Daneman N.

J Clin Microbiol. 2019 May 24;57(6). pii: e01780-18. doi: 10.1128/JCM.01780-18. Print 2019 Jun.


The association of adequate empirical treatment and time to recovery from bacteraemic urinary tract infections: a retrospective cohort study.

Wiggers JB, Sehgal P, Pinto R, MacFadden D, Daneman N.

Clin Microbiol Infect. 2019 Oct;25(10):1253-1258. doi: 10.1016/j.cmi.2019.02.027. Epub 2019 Mar 4.


Comparing prescribing and dispensing databases to study antibiotic use: a validation study of the Electronic Medical Record Administrative data Linked Database (EMRALD).

Schwartz KL, Wilton AS, Langford BJ, Brown KA, Daneman N, Garber G, Johnstone J, Adomako K, Achonu C, Tu K.

J Antimicrob Chemother. 2019 Jul 1;74(7):2091-2097. doi: 10.1093/jac/dkz033.


The predictors and economic burden of early-, mid- and late-onset cardiac implantable electronic device infections: a retrospective cohort study in Ontario, Canada.

Daneman N, Homenauth E, Saskin R, Ng R, Ha A, Wijeysundera HC.

Clin Microbiol Infect. 2020 Feb;26(2):255.e1-255.e6. doi: 10.1016/j.cmi.2019.02.009. Epub 2019 Feb 22.


The Association of Resident Communication Abilities and Antibiotic Use in Long-Term Care.

Saxena FE, Bronskill SE, Brown KA, Campitelli MA, Garber G, Langford B, Maxwell CJ, McCormack D, Schwartz KL, Daneman N.

J Am Geriatr Soc. 2019 Jun;67(6):1164-1173. doi: 10.1111/jgs.15771. Epub 2019 Jan 28.


One-year survival and admission to hospital for cardiovascular events among older residents of long-term care facilities who were prescribed intensive- and moderate-dose statins.

Campitelli MA, Maxwell CJ, Maclagan LC, Ko DT, Bell CM, Jeffs L, Morris AM, Lapane KL, Daneman N, Bronskill SE.

CMAJ. 2019 Jan 14;191(2):E32-E39. doi: 10.1503/cmaj.180853.


Late-career Physicians Prescribe Longer Courses of Antibiotics.

Fernandez-Lazaro CI, Brown KA, Langford BJ, Daneman N, Garber G, Schwartz KL.

Clin Infect Dis. 2019 Oct 15;69(9):1467-1475. doi: 10.1093/cid/ciy1130.


Empiric Antibiotic Treatment Thresholds for Serious Bacterial Infections: A Scenario-based Survey Study.

Cressman AM, MacFadden DR, Verma AA, Razak F, Daneman N.

Clin Infect Dis. 2019 Aug 30;69(6):930-937. doi: 10.1093/cid/ciy1031.


Shortening Antibiotic Treatment Durations for Bacteremia.

Daneman N, Fowler RA.

Clin Infect Dis. 2019 Sep 13;69(7):1099-1100. doi: 10.1093/cid/ciy1057. No abstract available.


Antimicrobial Stewardship Programs in Long-Term Care Settings: A Meta-Analysis and Systematic Review.

Wu JH, Langford BJ, Daneman N, Friedrich JO, Garber G.

J Am Geriatr Soc. 2019 Feb;67(2):392-399. doi: 10.1111/jgs.15675. Epub 2018 Dec 5.


Optimising detection and prevention of prosthetic joint infections.

Kandel C, Daneman N.

BMJ Qual Saf. 2019 May;28(5):349-351. doi: 10.1136/bmjqs-2018-009070. Epub 2018 Nov 22. No abstract available.


Regional variability in outpatient antibiotic use in Ontario, Canada: a retrospective cross-sectional study.

Schwartz KL, Achonu C, Brown KA, Langford B, Daneman N, Johnstone J, Garber G.

CMAJ Open. 2018 Oct 31;6(4):E445-E452. doi: 10.9778/cmajo.20180017. Print 2018 Oct-Dec.


Utility of Urine Cultures in Predicting Blood Culture Susceptibilities in Patients with Bacteremic Urinary Tract Infection.

Lam PW, Wiggers JB, Lo J, MacFadden DR, Daneman N.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01606-18. doi: 10.1128/AAC.01606-18. Print 2019 Jan.


Case conferences for infective endocarditis: A quality improvement initiative.

Tan C, Hansen MS, Cohen G, Boyle K, Yang A, Rishu A, Pinto R, Adhikari NKJ, Daneman N.

PLoS One. 2018 Oct 11;13(10):e0205528. doi: 10.1371/journal.pone.0205528. eCollection 2018.


Effect of Piperacillin-Tazobactam vs Meropenem on 30-Day Mortality for Patients With E coli or Klebsiella pneumoniae Bloodstream Infection and Ceftriaxone Resistance: A Randomized Clinical Trial.

Harris PNA, Tambyah PA, Lye DC, Mo Y, Lee TH, Yilmaz M, Alenazi TH, Arabi Y, Falcone M, Bassetti M, Righi E, Rogers BA, Kanj S, Bhally H, Iredell J, Mendelson M, Boyles TH, Looke D, Miyakis S, Walls G, Al Khamis M, Zikri A, Crowe A, Ingram P, Daneman N, Griffin P, Athan E, Lorenc P, Baker P, Roberts L, Beatson SA, Peleg AY, Harris-Brown T, Paterson DL; MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN).

JAMA. 2018 Sep 11;320(10):984-994. doi: 10.1001/jama.2018.12163. Erratum in: JAMA. 2019 Jun 18;321(23):2370.


Rationale and development of a business case for antimicrobial stewardship programs in acute care hospital settings.

Morris AM, Rennert-May E, Dalton B, Daneman N, Dresser L, Fanella S, Grant J, Keynan Y, Le Saux N, McDonald J, Shevchuk Y, Thirion D, Conly JM.

Antimicrob Resist Infect Control. 2018 Aug 29;7:104. doi: 10.1186/s13756-018-0396-z. eCollection 2018. Review.


Comparison of qPCR versus culture for the detection and quantification of Clostridium difficile environmental contamination.

MacDougall LK, Broukhanski G, Simor A, Johnstone J, Mubareka S, McGeer A, Daneman N, Garber G, Brown KA.

PLoS One. 2018 Aug 30;13(8):e0201569. doi: 10.1371/journal.pone.0201569. eCollection 2018.


Clinical and echocardiographic predictors of embolism in infective endocarditis: systematic review and meta-analysis.

Yang A, Tan C, Daneman N, Hansen MS, Habib G, Salaun E, Lavoute C, Hubert S, Adhikari NKJ.

Clin Microbiol Infect. 2019 Feb;25(2):178-187. doi: 10.1016/j.cmi.2018.08.010. Epub 2018 Aug 24.


Increased environmental sample area and recovery of Clostridium difficile spores from hospital surfaces by quantitative PCR and enrichment culture.

Brown KA, MacDougall LK, Valenta K, Simor A, Johnstone J, Mubareka S, Broukhanski G, Garber G, McGeer A, Daneman N.

Infect Control Hosp Epidemiol. 2018 Aug;39(8):917-923. doi: 10.1017/ice.2018.103.


Antimicrobial Stewardship and Intensive Care Unit Mortality: A Systematic Review.

Lindsay PJ, Rohailla S, Taggart LR, Lightfoot D, Havey T, Daneman N, Lowe C, Muller MP.

Clin Infect Dis. 2019 Feb 15;68(5):748-756. doi: 10.1093/cid/ciy550.


Predictors of Peripherally Inserted Central Catheter Occlusion in the Outpatient Parenteral Antimicrobial Therapy Setting.

Lam PW, Graham C, Leis JA, Daneman N.

Antimicrob Agents Chemother. 2018 Aug 27;62(9). pii: e00900-18. doi: 10.1128/AAC.00900-18. Print 2018 Sep.


Assessing the impact of antibiotic stewardship program elements on antibiotic use across acute-care hospitals: an observational study.

Langford BJ, Wu JH, Brown KA, Wang X, Leung V, Tan C, Garber G, Daneman N.

Infect Control Hosp Epidemiol. 2018 Aug;39(8):941-946. doi: 10.1017/ice.2018.121. Epub 2018 Jun 12.


Decision-support models for empiric antibiotic selection in Gram-negative bloodstream infections.

MacFadden DR, Coburn B, Shah N, Robicsek A, Savage R, Elligsen M, Daneman N.

Clin Microbiol Infect. 2019 Jan;25(1):108.e1-108.e7. doi: 10.1016/j.cmi.2018.03.029. Epub 2018 Apr 25.


Automatic notification and infectious diseases consultation for patients with Staphylococcus aureus bacteremia.

Djelic L, Andany N, Craig J, Daneman N, Simor A, Leis JA.

Diagn Microbiol Infect Dis. 2018 Jul;91(3):282-283. doi: 10.1016/j.diagmicrobio.2018.03.001. Epub 2018 Mar 3.


Impact of Defaulting to Single-Lumen Peripherally Inserted Central Catheters on Patient Outcomes: An Interrupted Time Series Study.

Lam PW, Volling C, Chan T, Wiggers JB, Castellani L, Wright J, Peckham K, Shadowitz S, Tasker S, MacFadden DR, Daneman N, Gold WL, Pugash R, Leis JA.

Clin Infect Dis. 2018 Aug 31;67(6):954-957. doi: 10.1093/cid/ciy301.


Re: The impact of antibiotics on the Intestinal microbiota needs to be re-defined in order to optimize the antibiotic usage; by Ruppe et al.

Coburn B, Daneman N, MacFadden DR, Rooney A.

Clin Microbiol Infect. 2018 Jul;24(7):783-784. doi: 10.1016/j.cmi.2018.03.021. Epub 2018 Mar 30. No abstract available.


Funding for Antimicrobial Stewardship Programs: A Customizable Business Case Template.

Le Saux N, Dalton B, Abbass K, Conly J, Daneman N, Dresser L, Fanella S, German G, Grant J, Keynan Y, Lau TTY, McDonald J, Nott C, Patrick D, Shevchuk Y, Thirion D, Morris A.

Can J Hosp Pharm. 2018 Jan-Feb;71(1):50-51. Epub 2018 Mar 7. No abstract available.


7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial.

Daneman N, Rishu AH, Pinto R, Aslanian P, Bagshaw SM, Carignan A, Charbonney E, Coburn B, Cook DJ, Detsky ME, Dodek P, Hall R, Kumar A, Lamontagne F, Lauzier F, Marshall JC, Martin CM, McIntyre L, Muscedere J, Reynolds S, Sligl W, Stelfox HT, Wilcox ME, Fowler RA; Canadian Critical Care Trials Group.

Trials. 2018 Feb 17;19(1):111. doi: 10.1186/s13063-018-2474-1.


Duration of antibiotic therapy for critically ill patients with bloodstream infections: A retrospective observational in Saudi Arabia.

Alqasim E, Aljohani S, Alshamrani M, Daneman N, Fowler R, Arabi Y.

Ann Thorac Med. 2018 Jan-Mar;13(1):63-65. doi: 10.4103/atm.ATM_236_17. No abstract available.


A decade of outpatient antimicrobial use in older adults in Ontario: a descriptive study.

Tan C, Graves E, Lu H, Chen A, Li S, Schwartz KL, Daneman N.

CMAJ Open. 2017 Dec 21;5(4):E878-E885. doi: 10.9778/cmajo.20170100.


Evaluating the Relationship Between Hospital Antibiotic Use and Antibiotic Resistance in Common Nosocomial Pathogens.

Wang A, Daneman N, Tan C, Brownstein JS, MacFadden DR.

Infect Control Hosp Epidemiol. 2017 Dec;38(12):1457-1463. doi: 10.1017/ice.2017.222. Epub 2017 Oct 26.


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