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Identifying Patients with Cirrhosis who Might Avoid Screening Endoscopy Based on Serum Albumin and Bilirubin and Platelet Counts.

Kew GS, Chen ZJ, A Yip WJ, Huang YWC, Tan LY, D Huang QY, Dan YY, Lee GH, Lee YM, Low HC, Lim SG, Gowans M, Muthiah MD, Tai BC, Tan PS.

Clin Gastroenterol Hepatol. 2019 Nov 8. pii: S1542-3565(19)31270-4. doi: 10.1016/j.cgh.2019.11.015. [Epub ahead of print] No abstract available.


A murine model demonstrating reversal of structural and functional correlates of cirrhosis with progenitor cell transplantation.

Muthiah MD, Huang DQ, Zhou L, Jumat NH, Choolani M, Chan JKY, Wee A, Lim SG, Dan YY.

Sci Rep. 2019 Oct 28;9(1):15446. doi: 10.1038/s41598-019-51189-7.


World Hepatitis Day 2019 - Bringing Medical Advances to Every Man.

Dan YY.

Ann Acad Med Singapore. 2019 Jul;48(7):199-200. No abstract available.


New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation.

Tan JL, Li F, Yeo JZ, Yong KJ, Bassal MA, Ng GH, Lee MY, Leong CY, Tan HK, Wu CS, Liu BH, Chan TH, Tan ZH, Chan YS, Wang S, Lim ZH, Toh TB, Hooi L, Low KN, Ma S, Kong NR, Stein AJ, Wu Y, Thangavelu MT, Suzuki A, Periyasamy G, Asara JM, Dan YY, Bonney GK, Chow EK, Lu GD, Ng HH, Kanagasundaram Y, Ng SB, Tam WL, Tenen DG, Chai L.

Gastroenterology. 2019 Aug 22. pii: S0016-5085(19)41242-0. doi: 10.1053/j.gastro.2019.08.022. [Epub ahead of print]


Risk factors for ribavirin treatment failure in Asian organ transplant recipients with chronic hepatitis E infection.

Low EXS, Tripon E, Lim K, Tan PS, Low HC, Dan YY, Lee YM, Muthiah M, Loo WM, Koh CJ, Phyo WW, Pang J, Lim SG, Lee GH.

World J Hepatol. 2019 Jun 27;11(6):553-561. doi: 10.4254/wjh.v11.i6.553.


Optimizing Use of Nonalcoholic Fatty Liver Disease Fibrosis Score, Fibrosis-4 Score, and Liver Stiffness Measurement to Identify Patients With Advanced Fibrosis.

Chan WK, Treeprasertsuk S, Goh GB, Fan JG, Song MJ, Charatcharoenwitthaya P, Duseja A, Dan YY, Imajo K, Nakajima A, Ho KY, Goh KL, Wong VW.

Clin Gastroenterol Hepatol. 2019 Nov;17(12):2570-2580.e37. doi: 10.1016/j.cgh.2019.03.006. Epub 2019 Mar 12.


Systematic review with meta-analysis: extrahepatic manifestations in chronic hepatitis C virus-infected patients in East Asia.

Younossi ZM, Henry L, P Ong J, Tanaka A, Eguchi Y, Mizokami M, Lim YS, Dan YY, Yu ML, Stepanova M.

Aliment Pharmacol Ther. 2019 Mar;49(6):644-653. doi: 10.1111/apt.15131. Epub 2019 Feb 13. Review.


Optimal liver stiffness measurement values for the diagnosis of significant fibrosis and cirrhosis in chronic liver disease in Singapore.

Chang PE, Hartono JL, Ngai YL, Dan YY, Lim KB, Chow WC.

Singapore Med J. 2019 Oct;60(10):532-537. doi: 10.11622/smedj.2018156. Epub 2018 Dec 17.


Improvement in Non-alcoholic Fatty Liver Disease Score Correlates with Weight Loss in Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy: a Two-Centre Study from an Asian Cohort.

Koh ZJ, Salgaonkar HP, Lee WJJ, Kim GW, Tan CH, Cheng A, Lomanto D, So JBY, Dan YY, Shabbir A.

Obes Surg. 2019 Mar;29(3):862-868. doi: 10.1007/s11695-018-3581-5.


Findings from a large Asian chronic hepatitis C real-life study.

Lim SG, Phyo WW, Shah SR, Win KM, Hamid S, Piratvisuth T, Tan SS, Dan YY, Lee YM, Ahmed T, Yang WL, Chen KP, Kamat M, Wadhawan M, Madan K, Mehta R, Shukla A, Dhore P, Eapen CE, Abraham P, Tyagi S, Koshy A, Bwa AH, Jafri W, Abid S, Arisar FAQ, Tanwandee T, Yin TP, Tee HP, Hj Md Said RB, Goh KL, Ho SH, Mohamed R, Abu Bakar N.

J Viral Hepat. 2018 Dec;25(12):1533-1542. doi: 10.1111/jvh.12989. Epub 2018 Sep 27.


Diagnostic utility of whole body CT scanning in patients with unexplained weight loss.

Goh Y, Dan YY, Chua W, Jagmohan P, Lee JK, Thian YL.

PLoS One. 2018 Jul 27;13(7):e0200686. doi: 10.1371/journal.pone.0200686. eCollection 2018.


Enhanced Liver Fibrosis Score as a Predictor of Hepatocellular Carcinoma.

Loo WM, Goh GB, Wang Y, Yuan JM, Ong L, Dan YY, Koh WP.

Clin Chem. 2018 Sep;64(9):1404-1405. doi: 10.1373/clinchem.2018.289108. Epub 2018 Jun 25. No abstract available.


Enhanced hepatic differentiation of human amniotic epithelial cells on polyethylene glycol-linked multiwalled carbon nanotube-coated hydrogels.

Zhao C, Lin JS, Choolani M, Dan YY, Pastorin G, Ho HK.

J Tissue Eng Regen Med. 2018 Jul;12(7):1556-1566. doi: 10.1002/term.2672. Epub 2018 May 18.


Consensus and contentious statements on the use of probiotics in clinical practice: A south east Asian gastro-neuro motility association working team report.

Gwee KA, Lee WW, Ling KL, Ooi CJ, Quak SH, Dan YY, Siah KT, Huang JG, Chua ASB, Hilmi IN, Raja Ali RA, Ong C, Simadibrata M, Abdullah M, Sollano JD, Leelakusolvong S, Gonlachanvit S, Lee YY, Ricaforte-Campos JD, Yin YK, Chong KM, Wong CY.

J Gastroenterol Hepatol. 2018 Oct;33(10):1707-1716. doi: 10.1111/jgh.14268. Epub 2018 Jun 12. Review.


Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy.

Zhao Y, Shuen TWH, Toh TB, Chan XY, Liu M, Tan SY, Fan Y, Yang H, Lyer SG, Bonney GK, Loh E, Chang KTE, Tan TC, Zhai W, Chan JKY, Chow EK, Chee CE, Lee GH, Dan YY, Chow PK, Toh HC, Lim SG, Chen Q.

Gut. 2018 Oct;67(10):1845-1854. doi: 10.1136/gutjnl-2017-315201. Epub 2018 Mar 30.


Editorial: NAFLD in Asia-clinical associations with advanced disease become clearer. Authors' reply.

Chan WK, Dan YY, Wong VW; GO ASIA Initiative.

Aliment Pharmacol Ther. 2018 Apr;47(7):1037-1038. doi: 10.1111/apt.14572. No abstract available.


Mouse models of non-alcoholic steatohepatitis: A reflection on recent literature.

Haczeyni F, Yeh MM, Ioannou GN, Leclercq IA, Goldin R, Dan YY, Yu J, Teoh NC, Farrell GC.

J Gastroenterol Hepatol. 2018 Jul;33(7):1312-1320. doi: 10.1111/jgh.14122. Epub 2018 Mar 24. Review.


Omega-6-derived oxylipin changes in serum of patients with hepatitis B virus-related liver diseases.

Lu Y, Fang J, Zou L, Cui L, Liang X, Lim SG, Dan YY, Ong CN.

Metabolomics. 2018 Jan 31;14(3):26. doi: 10.1007/s11306-018-1326-z.


Clinical features and treatment of nonalcoholic fatty liver disease across the Asia Pacific region-the GO ASIA initiative.

Chan WK, Treeprasertsuk S, Imajo K, Nakajima A, Seki Y, Kasama K, Kakizaki S, Fan JG, Song MJ, Yoon SK, Dan YY, Lesmana L, Ho KY, Goh KL, Wong VW.

Aliment Pharmacol Ther. 2018 Mar;47(6):816-825. doi: 10.1111/apt.14506. Epub 2018 Jan 14.


Systematic review and meta-analysis of algorithms used to identify drug-induced liver injury (DILI) in health record databases.

Tan EH, Low EXS, Dan YY, Tai BC.

Liver Int. 2018 Apr;38(4):742-753. doi: 10.1111/liv.13646. Epub 2017 Dec 16.


Neutrophils differentially attenuate immune response to Aspergillus infection through complement receptor 3 and induction of myeloperoxidase.

Goh JG, Ravikumar S, Win MS, Cao Q, Tan AL, Lim JHJ, Leong W, Herbrecht R, Troke PF, Kullberg BJ, Netea MG, Chng WJ, Dan YY, Chai LYA.

Cell Microbiol. 2018 Mar;20(3). doi: 10.1111/cmi.12798. Epub 2017 Dec 20.


Acute-on-chronic liver failure in a multi-ethnic Asian city: A comparison of patients identified by Asia-Pacific Association for the Study of the Liver and European Association for the Study of the Liver definitions.

Selva Rajoo A, Lim SG, Phyo WW, Tun T, Dan YY, Lee YM, Low HC, Lim K, Tan PS, Lee GH.

World J Hepatol. 2017 Oct 8;9(28):1133-1140. doi: 10.4254/wjh.v9.i28.1133.


Impact of ledipasvir/sofosbuvir on the work productivity of genotype 1 chronic hepatitis C patients in Asia.

Younossi ZM, Chan HLY, Dan YY, Lee MH, Lim YS, Kruger E, Tan SC.

J Viral Hepat. 2018 Mar;25(3):228-235. doi: 10.1111/jvh.12808. Epub 2017 Nov 29.


Long-Term Fate of Human Fetal Liver Progenitor Cells Transplanted in Injured Mouse Livers.

Irudayaswamy A, Muthiah M, Zhou L, Hung H, Jumat NHB, Haque J, Teoh N, Farrell G, Riehle KJ, Lin JS, Su LL, Chan JK, Choolani M, Wong PC, Wee A, Lim SG, Campbell J, Fausto N, Dan YY.

Stem Cells. 2018 Jan;36(1):103-113. doi: 10.1002/stem.2710. Epub 2017 Oct 13.


The Asia-Pacific Working Party on Non-alcoholic Fatty Liver Disease guidelines 2017-Part 2: Management and special groups.

Chitturi S, Wong VW, Chan WK, Wong GL, Wong SK, Sollano J, Ni YH, Liu CJ, Lin YC, Lesmana LA, Kim SU, Hashimoto E, Hamaguchi M, Goh KL, Fan J, Duseja A, Dan YY, Chawla Y, Farrell G, Chan HL.

J Gastroenterol Hepatol. 2018 Jan;33(1):86-98. doi: 10.1111/jgh.13856. Review. No abstract available.


Asia-Pacific Working Party on Non-alcoholic Fatty Liver Disease guidelines 2017-Part 1: Definition, risk factors and assessment.

Wong VW, Chan WK, Chitturi S, Chawla Y, Dan YY, Duseja A, Fan J, Goh KL, Hamaguchi M, Hashimoto E, Kim SU, Lesmana LA, Lin YC, Liu CJ, Ni YH, Sollano J, Wong SK, Wong GL, Chan HL, Farrell G.

J Gastroenterol Hepatol. 2018 Jan;33(1):70-85. doi: 10.1111/jgh.13857. Review. No abstract available.


Deriving and testing of dysplastic murine hepatocytes: A new platform in liver cancer research.

Pok S, Vohra H, Wehbe C, Barn VA, Arfianti E, Dan YY, Farrell GC, Teoh NC.

Exp Cell Res. 2017 Jul 1;356(1):48-56. doi: 10.1016/j.yexcr.2017.04.009. Epub 2017 Apr 10.


Management of hepatitis C virus infection in the Asia-Pacific region: an update.

Lim SG, Aghemo A, Chen PJ, Dan YY, Gane E, Gani R, Gish RG, Guan R, Jia JD, Lim K, Piratvisuth T, Shah S, Shiffman ML, Tacke F, Tan SS, Tanwandee T, Win KM, Yurdaydin C.

Lancet Gastroenterol Hepatol. 2017 Jan;2(1):52-62. doi: 10.1016/S2468-1253(16)30080-2. Epub 2016 Dec 10. Review.


Enhanced Peroxidase-Like Performance of Gold Nanoparticles by Hot Electrons.

Wang C, Shi Y, Dan YY, Nie XG, Li J, Xia XH.

Chemistry. 2017 May 17;23(28):6717-6723. doi: 10.1002/chem.201605380. Epub 2017 Mar 29.


Actomyosin contractility drives bile regurgitation as an early response during obstructive cholestasis.

Gupta K, Li Q, Fan JJ, Fong ELS, Song Z, Mo S, Tang H, Ng IC, Ng CW, Pawijit P, Zhuo S, Dong CY, Low BC, Wee A, Dan YY, Kanchanawong P, So P, Viasnoff V, Yu H.

J Hepatol. 2017 Jun;66(6):1231-1240. doi: 10.1016/j.jhep.2017.01.026. Epub 2017 Feb 9.


Intravoxel incoherent motion and diffusion tensor imaging of early renal fibrosis induced in a murine model of streptozotocin induced diabetes.

Yan YY, Hartono S, Hennedige T, Koh TS, Chan CM, Zhou L, Rumpel H, Martarello L, Khoo JB, Koh DM, Chuang KH, Tony Lim KH, Dan YY, Thng CH.

Magn Reson Imaging. 2017 May;38:71-76. doi: 10.1016/j.mri.2016.12.023. Epub 2016 Dec 28.


The impact of hepatitis C virus outside the liver: Evidence from Asia.

Younossi ZM, Tanaka A, Eguchi Y, Lim YS, Yu ML, Kawada N, Dan YY, Brooks-Rooney C, Negro F, Mondelli MU.

Liver Int. 2017 Feb;37(2):159-172. doi: 10.1111/liv.13272. Epub 2016 Nov 10. Review.


Chasing the facultative liver progenitor cell.

Dan YY.

Hepatology. 2016 Jul;64(1):297-300. doi: 10.1002/hep.28642. Epub 2016 May 27. No abstract available.


Asian consensus on the relationship between obesity and gastrointestinal and liver diseases.

Koh JC, Loo WM, Goh KL, Sugano K, Chan WK, Chiu WY, Choi MG, Gonlachanvit S, Lee WJ, Lee WJ, Lee YY, Lesmana LA, Li YM, Liu CJ, Matsuura B, Nakajima A, Ng EK, Sollano JD, Wong SK, Wong VW, Yang Y, Ho KY, Dan YY.

J Gastroenterol Hepatol. 2016 Aug;31(8):1405-13. doi: 10.1111/jgh.13385. Review.


Cost-effectiveness of strategy-based approach to treatment of genotype 1 chronic hepatitis C.

Zhao YJ, Khoo AL, Lin L, Teng M, Koh CJ, Lim SG, Lim BP, Dan YY.

J Gastroenterol Hepatol. 2016 Sep;31(9):1628-37. doi: 10.1111/jgh.13341.


Patient-reported Outcomes in Asian Patients With Chronic Hepatitis C Treated With Ledipasvir and Sofosbuvir.

Younossi ZM, Stepanova M, Chan HL, Lee MH, Yu ML, Dan YY, Choi MS, Henry L.

Medicine (Baltimore). 2016 Mar;95(9):e2702. doi: 10.1097/MD.0000000000002702.


Hepatitis C: An Eastern Perspective.

Dan YY, Lim SG.

Gastroenterol Clin North Am. 2015 Dec;44(4):793-805. doi: 10.1016/j.gtc.2015.07.007. Epub 2015 Sep 16. Review.


Chronic Infection With Camelid Hepatitis E Virus in a Liver Transplant Recipient Who Regularly Consumes Camel Meat and Milk.

Lee GH, Tan BH, Teo EC, Lim SG, Dan YY, Wee A, Aw PP, Zhu Y, Hibberd ML, Tan CK, Purdy MA, Teo CG.

Gastroenterology. 2016 Feb;150(2):355-7.e3. doi: 10.1053/j.gastro.2015.10.048. Epub 2015 Nov 6.


Dietary fatty acids and risk of hepatocellular carcinoma in the Singapore Chinese health study.

Koh WP, Dan YY, Goh GB, Jin A, Wang R, Yuan JM.

Liver Int. 2016 Jun;36(6):893-901. doi: 10.1111/liv.12978. Epub 2015 Oct 27.


Boceprevir early-access for advanced-fibrosis/cirrhosis in Asia-Pacific hepatitis C virus genotype 1 non-responders/relapsers.

Sukeepaisarnjaroen W, Pham T, Tanwandee T, Nazareth S, Galhenage S, Mollison L, Totten L, Wigg A, Altus R, Colman A, Morales B, Mason S, Jones T, Leembruggen N, Fragomelli V, Sendall C, Guan R, Sutedja D, Tan SS, Dan YY, Lee YM, Luman W, Teo EK, Than YM, Piratvisuth T, Lim SG.

World J Gastroenterol. 2015 Jul 28;21(28):8660-9. doi: 10.3748/wjg.v21.i28.8660.


Consensus cost-effectiveness model for treatment of chronic hepatitis B in Asia Pacific countries.

Dan YY, Wong JB, Hamid SS, Han KH, Jia JD, Liu CJ, Piratvisuth T, Lok AS, Lim SG.

Hepatol Int. 2014 Jul;8(3):382-94. doi: 10.1007/s12072-014-9549-1. Epub 2014 Jun 27.


A 2015 roadmap for the management of hepatitis C virus infections in Asia.

Lim SG, Dan YY.

Korean J Intern Med. 2015 Jul;30(4):423-33. doi: 10.3904/kjim.2015.30.4.423. Epub 2015 Jun 29. Review.


Hepatic differentiation of human amniotic epithelial cells and in vivo therapeutic effect on animal model of cirrhosis.

Lin JS, Zhou L, Sagayaraj A, Jumat NH, Choolani M, Chan JK, Biswas A, Wong PC, Lim SG, Dan YY.

J Gastroenterol Hepatol. 2015 Nov;30(11):1673-82. doi: 10.1111/jgh.12991.


Meta-analysis of the effectiveness of esomeprazole in gastroesophageal reflux disease and Helicobacter pylori infection.

Teng M, Khoo AL, Zhao YJ, Lin L, Lim BP, Wu TS, Dan YY.

J Clin Pharm Ther. 2015 Aug;40(4):368-75. doi: 10.1111/jcpt.12277. Epub 2015 Apr 20. Review.


Cost-effectiveness of boceprevir co-administration versus pegylated interferon-╬▒2b and ribavirin only for patients with hepatitis C genotype 1 in Singapore.

Dan YY, Ferrante SA, Elbasha EH, Hsu TY.

Antivir Ther. 2015;20(2):209-16. doi: 10.3851/IMP2825. Epub 2014 Aug 8.


Cost effectiveness of response-guided therapy with peginterferon in the treatment of chronic hepatitis B.

Lo AO, Wong VW, Wong GL, Chan HL, Dan YY.

Clin Gastroenterol Hepatol. 2015 Feb;13(2):377-385.e5. doi: 10.1016/j.cgh.2014.06.022. Epub 2014 Jun 30.


Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models.

Tan CY, Lai RC, Wong W, Dan YY, Lim SK, Ho HK.

Stem Cell Res Ther. 2014 Jun 10;5(3):76. doi: 10.1186/scrt465.


Commentary: vitamin D deficiency and liver cancer - cause, effect or myth?

Dan YY, Lim SG.

Aliment Pharmacol Ther. 2014 Jun;39(12):1429. doi: 10.1111/apt.12768. No abstract available.


A cost-effectiveness analysis evaluating endoscopic surveillance for gastric cancer for populations with low to intermediate risk.

Zhou HJ, Dan YY, Naidoo N, Li SC, Yeoh KG.

PLoS One. 2013 Dec 27;8(12):e83959. doi: 10.1371/journal.pone.0083959. eCollection 2013.


Oncofetal gene SALL4 in aggressive hepatocellular carcinoma.

Yong KJ, Gao C, Lim JS, Yan B, Yang H, Dimitrov T, Kawasaki A, Ong CW, Wong KF, Lee S, Ravikumar S, Srivastava S, Tian X, Poon RT, Fan ST, Luk JM, Dan YY, Salto-Tellez M, Chai L, Tenen DG.

N Engl J Med. 2013 Jun 13;368(24):2266-76. doi: 10.1056/NEJMoa1300297.

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