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Items: 1 to 50 of 194

1.

High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor that Promotes Airway Basal Stem Cell Homeostasis.

Aros CJ, Paul MK, Pantoja CJ, Bisht B, Meneses LK, Vijayaraj P, Sandlin JM, France B, Tse JA, Chen MW, Shia DW, Rickabaugh TM, Damoiseaux R, Gomperts BN.

Cell Rep. 2020 Feb 18;30(7):2055-2064.e5. doi: 10.1016/j.celrep.2020.01.059.

2.

Supervisors' pedagogies for supporting interns to learn intra- and interprofessional collaboration: a qualitative and quantitative ego network analysis.

de Groot E, van den Broek M, Fokkens JT, Witte JAM, Damoiseaux RAMJ, Zwart DLM.

J Interprof Care. 2020 Feb 9:1-9. doi: 10.1080/13561820.2020.1712336. [Epub ahead of print]

PMID:
32037921
3.

Chest discomfort at night and risk of acute coronary syndrome: cross-sectional study of telephone conversations.

Wouters LT, Zwart DL, Erkelens DC, Cheung NS, de Groot E, Damoiseaux RA, Hoes AW, Rutten FH.

Fam Pract. 2020 Jan 30. pii: cmaa005. doi: 10.1093/fampra/cmaa005. [Epub ahead of print]

PMID:
31996901
4.

Applying evidence-based medicine in general practice: a video-stimulated interview study on workplace-based observation.

Welink LS, Van Roy K, Damoiseaux RAMJ, Suijker HA, Pype P, de Groot E, Bartelink MEL.

BMC Fam Pract. 2020 Jan 8;21(1):5. doi: 10.1186/s12875-019-1073-x.

5.

Tinkering and overruling the computer decision support system: Working strategies of telephone triage nurses who assess the urgency of callers suspected of having an acute cardiac event.

Wouters LT, Zwart DL, Erkelens DC, Huijsmans M, Hoes AW, Damoiseaux RA, Rutten FH, de Groot E.

J Clin Nurs. 2020 Apr;29(7-8):1175-1186. doi: 10.1111/jocn.15168. Epub 2020 Jan 23.

PMID:
31887234
6.

Panel 5: Impact of otitis media on quality of life and development.

Homøe P, Heidemann CH, Damoiseaux RA, Lailach S, Lieu JEC, Phillips JS, Venekamp RP.

Int J Pediatr Otorhinolaryngol. 2020 Mar;130 Suppl 1:109837. doi: 10.1016/j.ijporl.2019.109837. Epub 2019 Dec 20.

PMID:
31883704
7.

Learning from patients about patient-centredness: A realist review: BEME Guide No. 60.

de Groot E, Schönrock-Adema J, Zwart D, Damoiseaux R, Van den Bogerd K, Diemers A, Grau Canét-Wittkampf C, Jaarsma D, Mol S, Bombeke K.

Med Teach. 2019 Dec 18:1-13. doi: 10.1080/0142159X.2019.1695767. [Epub ahead of print]

PMID:
31852313
8.

Development of a high-throughput screen to identify small molecule enhancers of sarcospan for the treatment of Duchenne muscular dystrophy.

Shu C, Kaxon-Rupp AN, Collado JR, Damoiseaux R, Crosbie RH.

Skelet Muscle. 2019 Dec 12;9(1):32. doi: 10.1186/s13395-019-0218-x.

9.

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression.

Garcia-Diaz A, Shin DS, Moreno BH, Saco J, Escuin-Ordinas H, Rodriguez GA, Zaretsky JM, Sun L, Hugo W, Wang X, Parisi G, Saus CP, Torrejon DY, Graeber TG, Comin-Anduix B, Hu-Lieskovan S, Damoiseaux R, Lo RS, Ribas A.

Cell Rep. 2019 Dec 10;29(11):3766. doi: 10.1016/j.celrep.2019.11.113. No abstract available.

10.

Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule.

Vijayaraj P, Minasyan A, Durra A, Karumbayaram S, Mehrabi M, Aros CJ, Ahadome SD, Shia DW, Chung K, Sandlin JM, Darmawan KF, Bhatt KV, Manze CC, Paul MK, Wilkinson DC, Yan W, Clark AT, Rickabaugh TM, Wallace WD, Graeber TG, Damoiseaux R, Gomperts BN.

Cell Rep. 2019 Dec 10;29(11):3488-3505.e9. doi: 10.1016/j.celrep.2019.11.019.

11.

A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells.

Ghezzi C, Wong A, Chen BY, Ribalet B, Damoiseaux R, Clark PM.

Nat Commun. 2019 Nov 29;10(1):5444. doi: 10.1038/s41467-019-13334-8.

12.

Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism.

Abt ER, Rosser EW, Durst MA, Lok V, Poddar S, Le TM, Cho A, Kim W, Wei L, Song J, Capri JR, Xu S, Wu N, Slavik R, Jung ME, Damoiseaux R, Czernin J, Donahue TR, Lavie A, Radu CG.

Cell Chem Biol. 2020 Feb 20;27(2):197-205.e6. doi: 10.1016/j.chembiol.2019.10.012. Epub 2019 Nov 13.

PMID:
31734178
13.

An in situ high-throughput screen identifies inhibitors of intracellular Burkholderia pseudomallei with therapeutic efficacy.

Bulterys PL, Toesca IJ, Norris MH, Maloy JP, Fitz-Gibbon ST, France B, Toffig B, Morselli M, Somprasong N, Pellegrini M, Schweizer HP, Tuanyok A, Damoiseaux R, French CT, Miller JF.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18597-18606. doi: 10.1073/pnas.1906388116. Epub 2019 Aug 22.

14.

PTPσ inhibitors promote hematopoietic stem cell regeneration.

Zhang Y, Roos M, Himburg H, Termini CM, Quarmyne M, Li M, Zhao L, Kan J, Fang T, Yan X, Pohl K, Diers E, Jin Gim H, Damoiseaux R, Whitelegge J, McBride W, Jung ME, Chute JP.

Nat Commun. 2019 Aug 14;10(1):3667. doi: 10.1038/s41467-019-11490-5.

15.

Optimisation of telephone triage of callers with symptoms suggestive of acute cardiovascular disease in out-of-hours primary care: observational design of the Safety First study.

Erkelens DC, Wouters LT, Zwart DL, Damoiseaux RA, De Groot E, Hoes AW, Rutten FH.

BMJ Open. 2019 Jul 1;9(7):e027477. doi: 10.1136/bmjopen-2018-027477.

16.

Understanding the Broker Role of Clinician-Scientists: A Realist Review on How They Link Research and Practice.

Barry M, de Groot E, Baggen Y, Smalbrugge M, Moolenaar N, Bartelink MEL, Damoiseaux RAMJ, Scherpbier N, Kluijtmans M.

Acad Med. 2019 Oct;94(10):1589-1598. doi: 10.1097/ACM.0000000000002819. Review.

PMID:
31169539
17.

Pneumococcal conjugate vaccines for preventing acute otitis media in children.

Fortanier AC, Venekamp RP, Boonacker CW, Hak E, Schilder AG, Sanders EA, Damoiseaux RA.

Cochrane Database Syst Rev. 2019 May 28;5:CD001480. doi: 10.1002/14651858.CD001480.pub5.

PMID:
31135969
18.

Leukemia Cell Cycle Chemical Profiling Identifies the G2-Phase Leukemia Specific Inhibitor Leusin-1.

Xia X, Lo YC, Gholkar AA, Senese S, Ong JY, Velasquez EF, Damoiseaux R, Torres JZ.

ACS Chem Biol. 2019 May 17;14(5):994-1001. doi: 10.1021/acschembio.9b00173. Epub 2019 May 8.

19.

Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor.

Mognol GP, González-Avalos E, Ghosh S, Spreafico R, Gudlur A, Rao A, Damoiseaux R, Hogan PG.

Proc Natl Acad Sci U S A. 2019 May 14;116(20):9959-9968. doi: 10.1073/pnas.1820604116. Epub 2019 Apr 24.

20.

Publisher Correction: Elastomeric sensor surfaces for high-throughput single-cell force cytometry.

Pushkarsky I, Tseng P, Black D, France B, Warfe L, Koziol-White CJ, Jester WF Jr, Trinh RK, Lin J, Scumpia PO, Morrison SL, Panettieri RA Jr, Damoiseaux R, Di Carlo D.

Nat Biomed Eng. 2018 Apr;2(4):265. doi: 10.1038/s41551-018-0207-0.

21.

1-(4-nitrobenzenesulfonyl)-4-penylpiperazine increases the number of Peyer's patch-associated regenerating crypts in the small intestines after radiation injury.

Bhat K, Duhachek-Muggy S, Ramanathan R, Saki M, Alli C, Medina P, Damoiseaux R, Whitelegge J, McBride WH, Schaue D, Vlashi E, Pajonk F.

Radiother Oncol. 2019 Mar;132:8-15. doi: 10.1016/j.radonc.2018.11.011. Epub 2018 Dec 20.

22.

A simple high-throughput approach identifies actionable drug sensitivities in patient-derived tumor organoids.

Phan N, Hong JJ, Tofig B, Mapua M, Elashoff D, Moatamed NA, Huang J, Memarzadeh S, Damoiseaux R, Soragni A.

Commun Biol. 2019 Feb 25;2:78. doi: 10.1038/s42003-019-0305-x. eCollection 2019.

23.

Facilitators and barriers to brokering between research and care by senior clinical-scientists in general practice and elderly care medicine.

Bartelink ME, Baggen Y, Stevens DE, Smalbrugge M, Scherpbier N, Damoiseaux RA, de Groot E.

Educ Prim Care. 2019 Mar;30(2):80-87. doi: 10.1080/14739879.2019.1570349. Epub 2019 Feb 12.

PMID:
30753793
24.

The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation.

Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, Ganz T, Sayre JW, McBride WH, Schaue D.

Radiat Res. 2019 Apr;191(4):323-334. doi: 10.1667/RR15231.1. Epub 2019 Feb 7.

PMID:
30730284
25.

Pain management in acute otitis media: a qualitative study exploring GPs' views and expectations parallel to a trial of an educational intervention.

van Uum RT, Sjoukes A, Venekamp RP, Schilder AG, de Groot E, Damoiseaux RA, Anthierens S.

BJGP Open. 2018 Oct 31;2(4):bjgpopen18X101620. doi: 10.3399/bjgpopen18X101620. eCollection 2018 Dec.

26.

Pain management in acute otitis media: a qualitative study of parents' views and expectations.

van Uum RT, Venekamp RP, Schilder AGM, Damoiseaux RAMJ, Anthierens S.

BMC Fam Pract. 2019 Jan 23;20(1):18. doi: 10.1186/s12875-019-0908-9.

27.

Impact of Repeated Influenza Immunization on Respiratory Illness in Children With Preexisting Medical Conditions.

de Hoog MLA, Venekamp RP, Damoiseaux RAMJ, Schilder AGM, Sanders EAM, Smit HA, Bruijning-Verhagen PCJL.

Ann Fam Med. 2019 Jan;17(1):7-13. doi: 10.1370/afm.2340.

28.

A scalable filtration method for high throughput screening based on cell deformability.

Gill NK, Ly C, Nyberg KD, Lee L, Qi D, Tofig B, Reis-Sobreiro M, Dorigo O, Rao J, Wiedemeyer R, Karlan B, Lawrenson K, Freeman MR, Damoiseaux R, Rowat AC.

Lab Chip. 2019 Jan 15;19(2):343-357. doi: 10.1039/c8lc00922h.

PMID:
30566156
29.

Challenges in measuring interprofessional-interorganisational collaboration with a questionnaire.

Meijer LJ, de Groot E, van Smeden M, Schellevis FG, Damoiseaux RA.

BJGP Open. 2018 Apr 21;2(1):bjgpopen18X101385. doi: 10.3399/bjgpopen18X101385. eCollection 2018 Apr.

30.

A Gelatin Microdroplet Platform for High-Throughput Sorting of Hyperproducing Single-Cell-Derived Microalgal Clones.

Li M, van Zee M, Riche CT, Tofig B, Gallaher SD, Merchant SS, Damoiseaux R, Goda K, Di Carlo D.

Small. 2018 Nov;14(44):e1803315. doi: 10.1002/smll.201803315. Epub 2018 Oct 4.

PMID:
30369052
31.

Tympanostomy tube otorrhea in children: prevention and treatment.

van Dongen TMA, Damoiseaux RAMJ, Schilder AGM.

Curr Opin Otolaryngol Head Neck Surg. 2018 Dec;26(6):437-440. doi: 10.1097/MOO.0000000000000493. Review.

PMID:
30234663
32.

Optimising pain management in children with acute otitis media through a primary care-based multifaceted educational intervention: study protocol for a cluster randomised controlled trial.

van Uum RT, Venekamp RP, Sjoukes A, van de Pol AC, de Wit GA, Schilder AGM, Damoiseaux RAMJ.

Trials. 2018 Sep 17;19(1):501. doi: 10.1186/s13063-018-2880-4.

33.

The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies.

Bowers PM, Boyle WJ, Damoiseaux R.

Methods Mol Biol. 2018;1827:479-489. doi: 10.1007/978-1-4939-8648-4_24.

34.

Prevalence and patterns of higher-order drug interactions in Escherichia coli.

Tekin E, White C, Kang TM, Singh N, Cruz-Loya M, Damoiseaux R, Savage VM, Yeh PJ.

NPJ Syst Biol Appl. 2018 Sep 3;4:31. doi: 10.1038/s41540-018-0069-9. eCollection 2018.

35.

Stressor interaction networks suggest antibiotic resistance co-opted from stress responses to temperature.

Cruz-Loya M, Kang TM, Lozano NA, Watanabe R, Tekin E, Damoiseaux R, Savage VM, Yeh PJ.

ISME J. 2019 Jan;13(1):12-23. doi: 10.1038/s41396-018-0241-7. Epub 2018 Aug 31.

36.

Obesity increases airway smooth muscle responses to contractile agonists.

Orfanos S, Jude J, Deeney BT, Cao G, Rastogi D, van Zee M, Pushkarsky I, Munoz HE, Damoiseaux R, Di Carlo D, Panettieri RA Jr.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L673-L681. doi: 10.1152/ajplung.00459.2017. Epub 2018 Aug 30.

37.

A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers.

Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR.

Cancer Metab. 2018 Jun 28;6:7. doi: 10.1186/s40170-018-0181-8. eCollection 2018.

38.

Design of a 15-month interprofessional workplace learning program to expand the added value of clinical pharmacists in primary care.

Hazen A, de Groot E, de Gier H, Damoiseaux R, Zwart D, Leendertse A.

Curr Pharm Teach Learn. 2018 May;10(5):618-626. doi: 10.1016/j.cptl.2018.01.006. Epub 2018 May 10.

PMID:
29986822
39.

Outpatient antibiotic use in Dutch infants after 10-valent pneumococcal vaccine introduction: a time-series analysis.

Fortanier AC, Venekamp RP, Stellato RK, Sanders EAM, Damoiseaux RAMJ, Hoes AW, Schilder AM.

BMJ Open. 2018 Jun 30;8(6):e020619. doi: 10.1136/bmjopen-2017-020619.

40.

A case study of nurse practitioner care compared with general practitioner care for children with respiratory tract infections.

van Vugt SF, van de Pol AC, Cleveringa FGW, Stellato RK, Kappers MP, de Wit NJ, Damoiseaux RAMJ.

J Adv Nurs. 2018 May 13. doi: 10.1111/jan.13712. [Epub ahead of print]

PMID:
29754411
41.

Reporter Gene Assays Using Viral Functional Genomics Libraries.

Welch G, Damoiseaux R, Miraglia L.

Methods Mol Biol. 2018;1755:121-133. doi: 10.1007/978-1-4939-7724-6_9.

PMID:
29671267
42.

Reporter Gene Assays Using Transfectable Functional Genomics Libraries.

Welch G, Damoiseaux R, Miraglia L.

Methods Mol Biol. 2018;1755:107-120. doi: 10.1007/978-1-4939-7724-6_8.

PMID:
29671266
43.

Making It All Work: Functional Genomics and Reporter Gene Assays.

Welch G, Damoiseaux R, Miraglia L.

Methods Mol Biol. 2018;1755:89-105. doi: 10.1007/978-1-4939-7724-6_7.

PMID:
29671265
44.

High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome.

Keegan A, Plath K, Damoiseaux R.

Methods Mol Biol. 2018;1755:75-87. doi: 10.1007/978-1-4939-7724-6_6.

PMID:
29671264
45.

Impact of acute otitis media clinical practice guidelines on antibiotic and analgesic prescriptions: a systematic review.

Deniz Y, van Uum RT, de Hoog MLA, Schilder AGM, Damoiseaux RAMJ, Venekamp RP.

Arch Dis Child. 2018 Jun;103(6):597-602. doi: 10.1136/archdischild-2017-314103. Epub 2018 Mar 3.

46.

Elastomeric sensor surfaces for high-throughput single-cell force cytometry.

Pushkarsky I, Tseng P, Black D, France B, Warfe L, Koziol-White CJ, Jester WF Jr, Trinh RK, Lin J, Scumpia PO, Morrison SL, Panettieri RA Jr, Damoiseaux R, Di Carlo D.

Nat Biomed Eng. 2018 Feb;2(2):124-137. doi: 10.1038/s41551-018-0193-2. Epub 2018 Feb 6. Erratum in: Nat Biomed Eng. 2018 Apr;2(4):265.

47.

Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation.

Senese S, Lo YC, Gholkar AA, Li CM, Huang Y, Mottahedeh J, Kornblum HI, Damoiseaux R, Torres JZ.

Oncotarget. 2017 Oct 19;8(61):104007-104021. doi: 10.18632/oncotarget.21945. eCollection 2017 Nov 28.

48.

[Health advocacy in medical student education].

Damoiseaux RAMJ, Soethout MBM.

Ned Tijdschr Geneeskd. 2017;161:D2326. Dutch.

PMID:
29241472
49.

A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma.

Laks DR, Oses-Prieto JA, Alvarado AG, Nakashima J, Chand S, Azzam DB, Gholkar AA, Sperry J, Ludwig K, Condro MC, Nazarian S, Cardenas A, Shih MYS, Damoiseaux R, France B, Orozco N, Visnyei K, Crisman TJ, Gao F, Torres JZ, Coppola G, Burlingame AL, Kornblum HI.

Neuro Oncol. 2018 May 18;20(6):764-775. doi: 10.1093/neuonc/nox215.

50.

Workplace learning through collaboration in primary healthcare: A BEME realist review of what works, for whom and in what circumstances: BEME Guide No. 46.

Mertens F, de Groot E, Meijer L, Wens J, Gemma Cherry M, Deveugele M, Damoiseaux R, Stes A, Pype P.

Med Teach. 2018 Feb;40(2):117-134. doi: 10.1080/0142159X.2017.1390216. Epub 2017 Nov 2. Review.

PMID:
29094626

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