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Items: 1 to 50 of 157


A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers.

Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR.

Cancer Metab. 2018 Jun 28;6:7. doi: 10.1186/s40170-018-0181-8. eCollection 2018.


Design of a 15-month interprofessional workplace learning program to expand the added value of clinical pharmacists in primary care.

Hazen A, de Groot E, de Gier H, Damoiseaux R, Zwart D, Leendertse A.

Curr Pharm Teach Learn. 2018 May;10(5):618-626. doi: 10.1016/j.cptl.2018.01.006. Epub 2018 May 10.


Outpatient antibiotic use in Dutch infants after 10-valent pneumococcal vaccine introduction: a time-series analysis.

Fortanier AC, Venekamp RP, Stellato RK, Sanders EAM, Damoiseaux RAMJ, Hoes AW, Schilder AM.

BMJ Open. 2018 Jun 30;8(6):e020619. doi: 10.1136/bmjopen-2017-020619.


A case study of nurse practitioner care compared with general practitioner care for children with respiratory tract infections.

van Vugt SF, van de Pol AC, Cleveringa FGW, Stellato RK, Kappers MP, de Wit NJ, Damoiseaux RAMJ.

J Adv Nurs. 2018 May 13. doi: 10.1111/jan.13712. [Epub ahead of print]


Reporter Gene Assays Using Viral Functional Genomics Libraries.

Welch G, Damoiseaux R, Miraglia L.

Methods Mol Biol. 2018;1755:121-133. doi: 10.1007/978-1-4939-7724-6_9.


Reporter Gene Assays Using Transfectable Functional Genomics Libraries.

Welch G, Damoiseaux R, Miraglia L.

Methods Mol Biol. 2018;1755:107-120. doi: 10.1007/978-1-4939-7724-6_8.


Making It All Work: Functional Genomics and Reporter Gene Assays.

Welch G, Damoiseaux R, Miraglia L.

Methods Mol Biol. 2018;1755:89-105. doi: 10.1007/978-1-4939-7724-6_7.


High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome.

Keegan A, Plath K, Damoiseaux R.

Methods Mol Biol. 2018;1755:75-87. doi: 10.1007/978-1-4939-7724-6_6.


Impact of acute otitis media clinical practice guidelines on antibiotic and analgesic prescriptions: a systematic review.

Deniz Y, van Uum RT, de Hoog MLA, Schilder AGM, Damoiseaux RAMJ, Venekamp RP.

Arch Dis Child. 2018 Jun;103(6):597-602. doi: 10.1136/archdischild-2017-314103. Epub 2018 Mar 3. Review.


Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation.

Senese S, Lo YC, Gholkar AA, Li CM, Huang Y, Mottahedeh J, Kornblum HI, Damoiseaux R, Torres JZ.

Oncotarget. 2017 Oct 19;8(61):104007-104021. doi: 10.18632/oncotarget.21945. eCollection 2017 Nov 28.


[Health advocacy in medical student education].

Damoiseaux RAMJ, Soethout MBM.

Ned Tijdschr Geneeskd. 2017;161:D2326. Dutch.


A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma.

Laks DR, Oses-Prieto JA, Alvarado AG, Nakashima J, Chand S, Azzam DB, Gholkar AA, Sperry J, Ludwig K, Condro MC, Nazarian S, Cardenas A, Shih MYS, Damoiseaux R, France B, Orozco N, Visnyei K, Crisman TJ, Gao F, Torres JZ, Coppola G, Burlingame AL, Kornblum HI.

Neuro Oncol. 2018 May 18;20(6):764-775. doi: 10.1093/neuonc/nox215.


Workplace learning through collaboration in primary healthcare: A BEME realist review of what works, for whom and in what circumstances: BEME Guide No. 46.

Mertens F, de Groot E, Meijer L, Wens J, Gemma Cherry M, Deveugele M, Damoiseaux R, Stes A, Pype P.

Med Teach. 2018 Feb;40(2):117-134. doi: 10.1080/0142159X.2017.1390216. Epub 2017 Nov 2.


Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection.

Watanabe M, Buth JE, Vishlaghi N, de la Torre-Ubieta L, Taxidis J, Khakh BS, Coppola G, Pearson CA, Yamauchi K, Gong D, Dai X, Damoiseaux R, Aliyari R, Liebscher S, Schenke-Layland K, Caneda C, Huang EJ, Zhang Y, Cheng G, Geschwind DH, Golshani P, Sun R, Novitch BG.

Cell Rep. 2017 Oct 10;21(2):517-532. doi: 10.1016/j.celrep.2017.09.047.


Exploiting Drug Addiction Mechanisms to Select against MAPKi-Resistant Melanoma.

Hong A, Moriceau G, Sun L, Lomeli S, Piva M, Damoiseaux R, Holmen SL, Sharpless NE, Hugo W, Lo RS.

Cancer Discov. 2018 Jan;8(1):74-93. doi: 10.1158/2159-8290.CD-17-0682. Epub 2017 Sep 18.


12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner.

Yoo EJ, Cao G, Koziol-White CJ, Ojiaku CA, Sunder K, Jude JA, Michael JV, Lam H, Pushkarsky I, Damoiseaux R, Di Carlo D, Ahn K, An SS, Penn RB, Panettieri RA Jr.

Br J Pharmacol. 2017 Dec;174(23):4383-4395. doi: 10.1111/bph.14040. Epub 2017 Nov 12.


Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential.

Lo YC, Senese S, France B, Gholkar AA, Damoiseaux R, Torres JZ.

Sci Rep. 2017 Sep 12;7(1):11261. doi: 10.1038/s41598-017-11508-2.


Recurrent Tumor Cell-Intrinsic and -Extrinsic Alterations during MAPKi-Induced Melanoma Regression and Early Adaptation.

Song C, Piva M, Sun L, Hong A, Moriceau G, Kong X, Zhang H, Lomeli S, Qian J, Yu CC, Damoiseaux R, Kelley MC, Dahlman KB, Scumpia PO, Sosman JA, Johnson DB, Ribas A, Hugo W, Lo RS.

Cancer Discov. 2017 Nov;7(11):1248-1265. doi: 10.1158/2159-8290.CD-17-0401. Epub 2017 Sep 1.


A comparative assessment of antiproliferative properties of resveratrol and ethanol leaf extract of Anogeissus leiocarpus (DC) Guill and Perr against HepG2 hepatocarcinoma cells.

Olugbami JO, Damoiseaux R, France B, Onibiyo EM, Gbadegesin MA, Sharma S, Gimzewski JK, Odunola OA.

BMC Complement Altern Med. 2017 Aug 2;17(1):381. doi: 10.1186/s12906-017-1873-2.


4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues.

Micewicz ED, Kim K, Iwamoto KS, Ratikan JA, Cheng G, Boxx GM, Damoiseaux RD, Whitelegge JP, Ruchala P, Nguyen C, Purbey P, Loo J, Deng G, Jung ME, Sayre JW, Norris AJ, Schaue D, McBride WH.

PLoS One. 2017 Jul 21;12(7):e0181577. doi: 10.1371/journal.pone.0181577. eCollection 2017.


The use of evidence during group meetings of Dutch general practitioners.

Ter Brugge BPH, Bartelink MEL, Damoiseaux RAMJ, de Groot E.

Educ Prim Care. 2017 Nov;28(6):307-312. doi: 10.1080/14739879.2017.1344934. Epub 2017 Jul 12.


Direct quantification of gamma H2AX by cell-based high throughput screening for evaluation of genotoxicity of pesticides in a human thyroid cell lines.

Hershman JM, France B, Hon K, Damoiseaux R.

Environ Mol Mutagen. 2017 Aug;58(7):522-528. doi: 10.1002/em.22103. Epub 2017 Jun 22.


Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression.

Garcia-Diaz A, Shin DS, Moreno BH, Saco J, Escuin-Ordinas H, Rodriguez GA, Zaretsky JM, Sun L, Hugo W, Wang X, Parisi G, Saus CP, Torrejon DY, Graeber TG, Comin-Anduix B, Hu-Lieskovan S, Damoiseaux R, Lo RS, Ribas A.

Cell Rep. 2017 May 9;19(6):1189-1201. doi: 10.1016/j.celrep.2017.04.031.


Atomic force microscopy correlates antimetastatic potentials of HepG2 cell line with its redox/energy status: effects of curcumin and Khaya senegalensis.

Olugbami JO, Damoiseaux R, France B, Gbadegesin MA, Stieg AZ, Sharma S, Odunola OA, Gimzewski JK.

J Integr Med. 2017 May;15(3):214-230. doi: 10.1016/S2095-4964(17)60337-6.


When more is less: Emergent suppressive interactions in three-drug combinations.

Beppler C, Tekin E, White C, Mao Z, Miller JH, Damoiseaux R, Savage VM, Yeh PJ.

BMC Microbiol. 2017 May 6;17(1):107. doi: 10.1186/s12866-017-1017-3.


Panel 1: Epidemiology and Diagnosis.

Homøe P, Kværner K, Casey JR, Damoiseaux RA, van Dongen TM, Gunasekera H, Jensen RG, Kvestad E, Morris PS, Weinreich HM.

Otolaryngol Head Neck Surg. 2017 Apr;156(4_suppl):S1-S21. doi: 10.1177/0194599816643510. Review.


Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44.

Miyata N, Tang Z, Conti MA, Johnson ME, Douglas CJ, Hasson SA, Damoiseaux R, Chang CA, Koehler CM.

J Biol Chem. 2017 Mar 31;292(13):5429-5442. doi: 10.1074/jbc.M116.770131. Epub 2017 Feb 6.


Acute Otitis Media in Children.

Venekamp RP, Damoiseaux RA, Schilder AG.

Am Fam Physician. 2017 Jan 15;95(2):109-110. Review. No abstract available.


[Diagnostic delay of pulmonary embolism].

Walen S, Damoiseaux RA, van den Berg JW.

Ned Tijdschr Geneeskd. 2016;160:D840. Dutch.


Engineering a Thermostable Keto Acid Decarboxylase Using Directed Evolution and Computationally Directed Protein Design.

Soh LMJ, Mak WS, Lin PP, Mi L, Chen FY, Damoiseaux R, Siegel JB, Liao JC.

ACS Synth Biol. 2017 Apr 21;6(4):610-618. doi: 10.1021/acssynbio.6b00240. Epub 2017 Jan 11.


Paracetamol (acetaminophen) or non-steroidal anti-inflammatory drugs, alone or combined, for pain relief in acute otitis media in children.

Sjoukes A, Venekamp RP, van de Pol AC, Hay AD, Little P, Schilder AG, Damoiseaux RA.

Cochrane Database Syst Rev. 2016 Dec 15;12:CD011534. doi: 10.1002/14651858.CD011534.pub2. Review.


[Diversity and quality in medical training].

Damoiseaux RA, Blankenstein AH, Vermeulen MI.

Ned Tijdschr Geneeskd. 2016;160:D670. Review. Dutch.


Antibiotic Treatment for First Episode of Acute Otitis Media Is Not Associated with Future Recurrences.

Te Molder M, de Hoog ML, Uiterwaal CS, van der Ent CK, Smit HA, Schilder AG, Damoiseaux RA, Venekamp RP.

PLoS One. 2016 Sep 15;11(9):e0160560. doi: 10.1371/journal.pone.0160560. eCollection 2016.


[Being a supervisor demands other skills than being a doctor].

Damoiseaux RA, Vermeulen MI.

Ned Tijdschr Geneeskd. 2016;160:D784. Review. Dutch.


Intraprofessional collaboration and learning between specialists and general practitioners during postgraduate training: a qualitative study.

Meijer LJ, de Groot E, Blaauw-Westerlaken M, Damoiseaux RA.

BMC Health Serv Res. 2016 Aug 11;16(a):376. doi: 10.1186/s12913-016-1619-8.


Impact of Early-Onset Acute Otitis Media on Multiple Recurrences and Associated Health Care Use.

de Hoog MLA, Fortanier AC, Smit HA, Uiterwaal CPM, van der Ent CK, Schilder A, Damoiseaux RMJ, Venekamp RP, Bruijning-Verhagen P.

J Pediatr. 2016 Oct;177:286-291.e1. doi: 10.1016/j.jpeds.2016.06.066. Epub 2016 Aug 4.


Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner.

Koziol-White CJ, Yoo EJ, Cao G, Zhang J, Papanikolaou E, Pushkarsky I, Andrews A, Himes BE, Damoiseaux RD, Liggett SB, Di Carlo D, Kurten RC, Panettieri RA Jr.

Br J Pharmacol. 2016 Sep;173(18):2726-38. doi: 10.1111/bph.13542. Epub 2016 Aug 3.


[Peer feedback for trainers in general practice].

Damoiseaux RA, Truijens L.

Ned Tijdschr Geneeskd. 2016;160:D268. Dutch.


3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping.

Lo YC, Senese S, Damoiseaux R, Torres JZ.

ACS Chem Biol. 2016 Aug 19;11(8):2244-53. doi: 10.1021/acschembio.6b00253. Epub 2016 Jun 20.


Poor Performance Among Trainees in a Dutch Postgraduate GP Training Program.

Vermeulen MI, Kuyvenhoven MM, de Groot E, Zuithoff NP, Pieters HM, van der Graaf Y, Damoiseaux RA.

Fam Med. 2016 Jun;48(6):430-8.


Diagnostic delay of pulmonary embolism in primary and secondary care: a retrospective cohort study.

Walen S, Damoiseaux RA, Uil SM, van den Berg JW.

Br J Gen Pract. 2016 Jun;66(647):e444-50. doi: 10.3399/bjgp16X685201. Epub 2016 Apr 25.


Characterization and evolution of an activator-independent methanol dehydrogenase from Cupriavidus necator N-1.

Wu TY, Chen CT, Liu JT, Bogorad IW, Damoiseaux R, Liao JC.

Appl Microbiol Biotechnol. 2016 Jun;100(11):4969-83. doi: 10.1007/s00253-016-7320-3. Epub 2016 Feb 5.


Discovery of Structurally Diverse Small-Molecule Compounds with Broad Antiviral Activity against Enteroviruses.

Zuo J, Kye S, Quinn KK, Cooper P, Damoiseaux R, Krogstad P.

Antimicrob Agents Chemother. 2015 Dec 28;60(3):1615-26. doi: 10.1128/AAC.02646-15.


A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase.

Minkovsky A, Sahakyan A, Bonora G, Damoiseaux R, Dimitrova E, Rubbi L, Pellegrini M, Radu CG, Plath K.

Epigenetics Chromatin. 2015 Oct 13;8:42. doi: 10.1186/s13072-015-0034-4. eCollection 2015.


Copper status of exposed microorganisms influences susceptibility to metallic nanoparticles.

Reyes VC, Spitzmiller MR, Hong-Hermesdorf A, Kropat J, Damoiseaux RD, Merchant SS, Mahendra S.

Environ Toxicol Chem. 2016 May;35(5):1148-58. doi: 10.1002/etc.3254. Epub 2016 Mar 9.


[Prescribing antibiotics for sore throat: a persistent habit].

Damoiseaux RA, Venekamp RP.

Ned Tijdschr Geneeskd. 2015;159:A9419. Dutch.


Novel Arenavirus Entry Inhibitors Discovered by Using a Minigenome Rescue System for High-Throughput Drug Screening.

Rathbun JY, Droniou ME, Damoiseaux R, Haworth KG, Henley JE, Exline CM, Choe H, Cannon PM.

J Virol. 2015 Aug;89(16):8428-43. doi: 10.1128/JVI.00997-15. Epub 2015 Jun 3.


Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression.

Huynh TP, Barwe SP, Lee SJ, McSpadden R, Franco OE, Hayward SW, Damoiseaux R, Grubbs SS, Petrelli NJ, Rajasekaran AK.

PLoS One. 2015 Apr 2;10(4):e0122442. doi: 10.1371/journal.pone.0122442. eCollection 2015.


Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens.

Lo YC, Senese S, Li CM, Hu Q, Huang Y, Damoiseaux R, Torres JZ.

PLoS Comput Biol. 2015 Mar 31;11(3):e1004153. doi: 10.1371/journal.pcbi.1004153. eCollection 2015 Mar.


Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1.

Ting PY, Damoiseaux R, Titz B, Bradley KA, Graeber TG, Fernández-Vega V, Bannister TD, Chase P, Nair R, Scampavia L, Hodder P, Spicer TP, Colicelli J.

PLoS One. 2015 Mar 26;10(3):e0121833. doi: 10.1371/journal.pone.0121833. eCollection 2015.

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