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miR-301a expression: Diagnostic and prognostic marker for prostate cancer.

Kolluru V, Chandrasekaran B, Tyagi A, Dervishi A, Ankem M, Yan X, Maiying K, Alatassi H, Shaheen SP, C Messer J, Edwards A, Haddad A, Damodaran C.

Urol Oncol. 2018 Sep 5. pii: S1078-1439(18)30269-2. doi: 10.1016/j.urolonc.2018.07.014. [Epub ahead of print]


The Chemopreventive effect of Withaferin A on spontaneous and Inflammation-associated colon carcinogenesis models.

Chandrasekaran B, Pal D, Kolluru V, Tyagi A, Baby B, Dahiya NR, Khafateh Y, Houda A, Ankem MK, Sharma AK, Damodaran C.

Carcinogenesis. 2018 Aug 16. doi: 10.1093/carcin/bgy109. [Epub ahead of print]


A natural molecule, urolithin A, downregulates androgen receptor activation and suppresses growth of prostate cancer.

Dahiya NR, Chandrasekaran B, Kolluru V, Ankem M, Damodaran C, Vadhanam MV.

Mol Carcinog. 2018 Oct;57(10):1332-1341. doi: 10.1002/mc.22848. Epub 2018 Aug 1.


Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer.

Pal D, Tyagi A, Chandrasekaran B, Alattasi H, Ankem MK, Sharma AK, Damodaran C.

Cell Death Dis. 2018 Jul 23;9(8):798. doi: 10.1038/s41419-018-0810-8.


Inhibition of p53 prevents diabetic cardiomyopathy by preventing early-stage apoptosis and cell senescence, reduced glycolysis, and impaired angiogenesis.

Gu J, Wang S, Guo H, Tan Y, Liang Y, Feng A, Liu Q, Damodaran C, Zhang Z, Keller BB, Zhang C, Cai L.

Cell Death Dis. 2018 Jan 23;9(2):82. doi: 10.1038/s41419-017-0093-5.


Differentially Expressed mRNA Targets of Differentially Expressed miRNAs Predict Changes in the TP53 Axis and Carcinogenesis-Related Pathways in Human Keratinocytes Chronically Exposed to Arsenic.

Al-Eryani L, Waigel S, Tyagi A, Peremarti J, Jenkins SF, Damodaran C, States JC.

Toxicol Sci. 2018 Apr 1;162(2):645-654. doi: 10.1093/toxsci/kfx292.


Fenofibrate inhibits mTOR-p70S6K signaling and simultaneously induces cell death in human prostate cancer cells.

Lian X, Gu J, Gao B, Li Y, Damodaran C, Wei W, Fu Y, Cai L.

Biochem Biophys Res Commun. 2018 Jan 29;496(1):70-75. doi: 10.1016/j.bbrc.2017.12.168. Epub 2018 Jan 3.


Molecular insights: Suppression of EGFR and AKT activation by a small molecule in non-small cell lung cancer.

Chandrasekaran B, Tyagi A, Sharma AK, Cai L, Ankem M, Damodaran C.

Genes Cancer. 2017 Sep;8(9-10):713-724. doi: 10.18632/genesandcancer.154.


Induction of Plac8 promotes pro-survival function of autophagy in cadmium-induced prostate carcinogenesis.

Kolluru V, Pal D, Papu John AMS, Ankem MK, Freedman JH, Damodaran C.

Cancer Lett. 2017 Nov 1;408:121-129. doi: 10.1016/j.canlet.2017.08.023. Epub 2017 Aug 24.


Inhibition of autophagy prevents cadmium-induced prostate carcinogenesis.

Pal D, Suman S, Kolluru V, Sears S, Das TP, Alatassi H, Ankem MK, Freedman JH, Damodaran C.

Br J Cancer. 2017 Jun 27;117(1):56-64. doi: 10.1038/bjc.2017.143. Epub 2017 Jun 6.


Withaferin A Inhibits Prostate Carcinogenesis in a PTEN-deficient Mouse Model of Prostate Cancer.

Moselhy J, Suman S, Alghamdi M, Chandarasekharan B, Das TP, Houda A, Ankem M, Damodaran C.

Neoplasia. 2017 Jun;19(6):451-459. doi: 10.1016/j.neo.2017.04.005. Epub 2017 May 7.


Targeting aberrant expression of Notch-1 in ALDH+ cancer stem cells in breast cancer.

Pal D, Kolluru V, Chandrasekaran B, Baby BV, Aman M, Suman S, Sirimulla S, Sanders MA, Alatassi H, Ankem MK, Damodaran C.

Mol Carcinog. 2017 Mar;56(3):1127-1136. doi: 10.1002/mc.22579. Epub 2016 Nov 5.


Synthesis of Psoralidin derivatives and their anticancer activity: First synthesis of Lespeflorin I1.

Pahari P, Saikia UP, Das TP, Damodaran C, Rohr J.

Tetrahedron. 2016 Jun 9;72(23):3324-3334.


Oral administration of withaferin A inhibits carcinogenesis of prostate in TRAMP model.

Suman S, Das TP, Moselhy J, Pal D, Kolluru V, Alatassi H, Ankem MK, Damodaran C.

Oncotarget. 2016 Aug 16;7(33):53751-53761. doi: 10.18632/oncotarget.10733.


miR-301a expression: A prognostic marker for prostate cancer.

Damodaran C, Das TP, Papu John AM, Suman S, Kolluru V, Morris TJ, Faber EN, Rai SN, Messer JC, Alatassi H, Ankem MK.

Urol Oncol. 2016 Aug;34(8):336.e13-20. doi: 10.1016/j.urolonc.2016.03.009. Epub 2016 Apr 26.


Activation of AKT negatively regulates the pro-apoptotic function of death-associated protein kinase 3 (DAPK3) in prostate cancer.

Das TP, Suman S, Papu John AM, Pal D, Edwards A, Alatassi H, Ankem MK, Damodaran C.

Cancer Lett. 2016 Jul 28;377(2):134-9. doi: 10.1016/j.canlet.2016.04.028. Epub 2016 Apr 25.


Oxidative Stress: A Promising Target for Chemoprevention.

John AS, Ankem MK, Damodaran C.

Curr Pharmacol Rep. 2016 Apr;2(2):73-81. Epub 2016 Feb 5.


Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer.

Das TP, Suman S, Alatassi H, Ankem MK, Damodaran C.

Cell Death Dis. 2016 Feb 25;7:e2111. doi: 10.1038/cddis.2015.403.


Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells.

Suman S, Das TP, Sirimulla S, Alatassi H, Ankem MK, Damodaran C.

Oncotarget. 2016 Mar 22;7(12):13854-64. doi: 10.18632/oncotarget.7351.


Natural Products That Target Cancer Stem Cells.

Moselhy J, Srinivasan S, Ankem MK, Damodaran C.

Anticancer Res. 2015 Nov;35(11):5773-88. Review.


Targeting Notch Signaling in Colorectal Cancer.

Suman S, Das TP, Ankem MK, Damodaran C.

Curr Colorectal Cancer Rep. 2014 Dec 1;10(4):411-416.


Erythematous seropurulent ulcerations.

Nino T, Lee S, Macknet C, Hirokane J, Damodaran C.

Cutis. 2014 Oct;94(4):E4-6. No abstract available.


A review of molecular events of cadmium-induced carcinogenesis.

Luevano J, Damodaran C.

J Environ Pathol Toxicol Oncol. 2014;33(3):183-94. Review.


The pro-apoptotic role of autophagy in breast cancer.

Suman S, Das TP, Reddy R, Nyakeriga AM, Luevano JE, Konwar D, Pahari P, Damodaran C.

Br J Cancer. 2014 Jul 15;111(2):309-17. doi: 10.1038/bjc.2014.203. Epub 2014 Jun 19.


Pathogenic and therapeutic role of miRNAs in breast cancer.

Kurisetty VV, Lakshmanaswamy R, Damodaran C.

Front Biosci (Landmark Ed). 2014 Jan 1;19:1-11. Review.


Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells.

Suman S, Das TP, Damodaran C.

Br J Cancer. 2013 Nov 12;109(10):2587-96. doi: 10.1038/bjc.2013.642. Epub 2013 Oct 15.


Withaferin A, a steroidal lactone from Withania somnifera, induces mitotic catastrophe and growth arrest in prostate cancer cells.

Roy RV, Suman S, Das TP, Luevano JE, Damodaran C.

J Nat Prod. 2013 Oct 25;76(10):1909-15. doi: 10.1021/np400441f. Epub 2013 Sep 30.


Activation of AKT signaling promotes epithelial-mesenchymal transition and tumor growth in colorectal cancer cells.

Suman S, Kurisetty V, Das TP, Vadodkar A, Ramos G, Lakshmanaswamy R, Damodaran C.

Mol Carcinog. 2014 Feb;53 Suppl 1:E151-60. doi: 10.1002/mc.22076. Epub 2013 Sep 2.


Strongyloides stercoralis infection in transplanted patients.

Sadjadi SA, Damodaran C, Sharif M.

Am J Case Rep. 2013 Jun 17;14:205-9. doi: 10.12659/AJCR.889341. Print 2013.


Molecular interplay between cdk4 and p21 dictates G0/G1 cell cycle arrest in prostate cancer cells.

Gulappa T, Reddy RS, Suman S, Nyakeriga AM, Damodaran C.

Cancer Lett. 2013 Sep 1;337(2):177-83. doi: 10.1016/j.canlet.2013.05.014. Epub 2013 May 16.


Induction of reactive oxygen species generation inhibits epithelial-mesenchymal transition and promotes growth arrest in prostate cancer cells.

Das TP, Suman S, Damodaran C.

Mol Carcinog. 2014 Jul;53(7):537-47. doi: 10.1002/mc.22014. Epub 2013 Mar 8.


The anticancer effect of 2'-3'-dehydrosalannol on triple-negative breast cancer cells.

Boopalan T, Arumugam A, Damodaran C, Rajkumar L.

Anticancer Res. 2012 Jul;32(7):2801-6.


Chemoprevention of breast cancer by dietary compounds.

Vadodkar AS, Suman S, Lakshmanaswamy R, Damodaran C.

Anticancer Agents Med Chem. 2012 Dec;12(10):1185-202. Review.


Landomycins P-W, cytotoxic angucyclines from Streptomyces cyanogenus S-136.

Shaaban KA, Srinivasan S, Kumar R, Damodaran C, Rohr J.

J Nat Prod. 2011 Jan 28;74(1):2-11. doi: 10.1021/np100469y. Epub 2010 Dec 28.


11-Deoxylandomycinone and landomycins X-Z, new cytotoxic angucyclin(on)es from a Streptomyces cyanogenus K62 mutant strain.

Shaaban KA, Stamatkin C, Damodaran C, Rohr J.

J Antibiot (Tokyo). 2011 Jan;64(1):141-50. doi: 10.1038/ja.2010.121. Epub 2010 Oct 27.


Activating stress-activated protein kinase-mediated cell death and inhibiting epidermal growth factor receptor signaling: a promising therapeutic strategy for prostate cancer.

Kumar R, Srinivasan S, Pahari P, Rohr J, Damodaran C.

Mol Cancer Ther. 2010 Sep;9(9):2488-96. doi: 10.1158/1535-7163.MCT-10-0180. Epub 2010 Aug 24.


Aplysinopsin analogs: Synthesis and anti-proliferative activity of substituted (Z)-5-(N-benzylindol-3-ylmethylene)imidazolidine-2,4-diones.

Thirupathi Reddy Y, Narsimha Reddy P, Koduru S, Damodaran C, Crooks PA.

Bioorg Med Chem. 2010 May 15;18(10):3570-4. doi: 10.1016/j.bmc.2010.03.054. Epub 2010 Mar 27.


Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis.

Koduru S, Kumar R, Srinivasan S, Evers MB, Damodaran C.

Mol Cancer Ther. 2010 Jan;9(1):202-10. doi: 10.1158/1535-7163.MCT-09-0771. Epub 2010 Jan 6.


Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer.

Srinivasan S, Kumar R, Koduru S, Chandramouli A, Damodaran C.

Apoptosis. 2010 Feb;15(2):153-61. doi: 10.1007/s10495-009-0416-9.


Editorial comment.

Damodaran C.

J Urol. 2009 Oct;182(4):1356. doi: 10.1016/j.juro.2009.06.148. Epub 2009 Aug 14. No abstract available.


Diosgenin targets Akt-mediated prosurvival signaling in human breast cancer cells.

Srinivasan S, Koduru S, Kumar R, Venguswamy G, Kyprianou N, Damodaran C.

Int J Cancer. 2009 Aug 15;125(4):961-7. doi: 10.1002/ijc.24419. Erratum in: Int J Cancer. 2015 Jan 15;136(2):E1.


Psoralidin, an herbal molecule, inhibits phosphatidylinositol 3-kinase-mediated Akt signaling in androgen-independent prostate cancer cells.

Kumar R, Srinivasan S, Koduru S, Pahari P, Rohr J, Kyprianou N, Damodaran C.

Cancer Prev Res (Phila). 2009 Mar;2(3):234-43. doi: 10.1158/1940-6207.CAPR-08-0129. Epub 2009 Feb 17. Retraction in: Cancer Prev Res (Phila). 2011 Nov;4(11):1945.


Identification of a potent herbal molecule for the treatment of breast cancer.

Koduru S, Sowmyalakshmi S, Kumar R, Gomathinayagam R, Rohr J, Damodaran C.

BMC Cancer. 2009 Jan 30;9:41. doi: 10.1186/1471-2407-9-41.


Anticancer mechanism of plumbagin, a natural compound, on non-small cell lung cancer cells.

Gomathinayagam R, Sowmyalakshmi S, Mardhatillah F, Kumar R, Akbarsha MA, Damodaran C.

Anticancer Res. 2008 Mar-Apr;28(2A):785-92.


Mithramycin analogues generated by combinatorial biosynthesis show improved bioactivity.

Baig I, Perez M, Braña AF, Gomathinayagam R, Damodaran C, Salas JA, Méndez C, Rohr J.

J Nat Prod. 2008 Feb;71(2):199-207. doi: 10.1021/np0705763. Epub 2008 Jan 15.


The radiosensitization effect of 2-deoxy-D-glucose on human glioma cells.

Gomathinayagam R, Damodaran C.

Cancer Biol Ther. 2006 Sep;5(9):1152-3. Epub 2006 Sep 17. No abstract available.


Phylogenetics of worldwide human populations as determined by polymorphic Alu insertions.

Antunez-de-Mayolo G, Antunez-de-Mayolo A, Antunez-de-Mayolo P, Papiha SS, Hammer M, Yunis JJ, Yunis EJ, Damodaran C, Martinez de Pancorbo M, Caeiro JL, Puzyrev VP, Herrera RJ.

Electrophoresis. 2002 Sep;23(19):3346-56.


Allele frequency distribution for nine fluorescent based STR loci in Tamil population (South India).

Panneerchelvam S, Vanaja N, Goud ChV, Sheeba A, Rao GV, Damodaran C.

J Forensic Sci. 2002 Jan;47(1):226-7. No abstract available.


Gene frequencies of 12 STR loci in an endogamous Badaga population (South India).

Panneerchelvan S, Gunachandran N, Vanaja N, Balachandran R, Sivapriya V, Baskar D, Nalina K, Rajmohan S, Damodaran C.

J Forensic Sci. 2001 Jul;46(4):994-5. No abstract available.


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