Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 40

1.

Targeted gene panel sequencing for the rapid diagnosis of acutely ill infants.

Brunelli L, Jenkins SM, Gudgeon JM, Bleyl SB, Miller CE, Tvrdik T, Dames SA, Ostrander B, Daboub JAF, Zielinski BA, Zinkhan EK, Underhill HR, Wilson T, Bonkowsky JL, Yost CC, Botto LD, Jenkins J, Pysher TJ, Bayrak-Toydemir P, Mao R.

Mol Genet Genomic Med. 2019 Jul;7(7):e00796. doi: 10.1002/mgg3.796. Epub 2019 Jun 13.

2.

NMR- and MD simulation-based structural characterization of the membrane-associating FATC domain of ataxia telangiectasia mutated.

Abd Rahim MS, Cherniavskyi YK, Tieleman DP, Dames SA.

J Biol Chem. 2019 Apr 26;294(17):7098-7112. doi: 10.1074/jbc.RA119.007653. Epub 2019 Mar 13.

PMID:
30867195
4.

NMR analysis of the backbone dynamics of the small GTPase Rheb and its interaction with the regulatory protein FKBP38.

De Cicco M, Kiss L, Dames SA.

FEBS Lett. 2018 Jan;592(1):130-146. doi: 10.1002/1873-3468.12925. Epub 2017 Dec 14.

5.

Target of rapamycin FATC domain as a general membrane anchor: The FKBP-12 like domain of FKBP38 as a case study.

De Cicco M, Milroy LG, Dames SA.

Protein Sci. 2018 Feb;27(2):546-560. doi: 10.1002/pro.3321. Epub 2017 Oct 30.

6.

A rapid gene sequencing panel strategy to facilitate precision neonatal medicine.

Brunelli L, Mao R, Jenkins SM, Bleyl SB, Dames SA, Miller CE, Ostrander B, Tvrdik T, Andrews S, Flores J, Patel S, Gudgeon JM, Schaefer S.

Am J Med Genet A. 2017 Jul;173(7):1979-1982. doi: 10.1002/ajmg.a.38259. Epub 2017 May 12. No abstract available.

PMID:
28497657
7.

Oxidative Unfolding of the Rubredoxin Domain and the Natively Disordered N-terminal Region Regulate the Catalytic Activity of Mycobacterium tuberculosis Protein Kinase G.

Wittwer M, Luo Q, Kaila VR, Dames SA.

J Biol Chem. 2016 Dec 30;291(53):27062-27072. doi: 10.1074/jbc.M116.747089. Epub 2016 Nov 3.

8.
9.

A Rigorous and Efficient Method To Reweight Very Large Conformational Ensembles Using Average Experimental Data and To Determine Their Relative Information Content.

Leung HT, Bignucolo O, Aregger R, Dames SA, Mazur A, Bernèche S, Grzesiek S.

J Chem Theory Comput. 2016 Jan 12;12(1):383-94. doi: 10.1021/acs.jctc.5b00759. Epub 2015 Dec 2.

PMID:
26632648
10.

Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting.

De Cicco M, Rahim MS, Dames SA.

Membranes (Basel). 2015 Sep 29;5(4):553-75. doi: 10.3390/membranes5040553. Review.

11.

Expression and purification of the natively disordered and redox sensitive metal binding regions of Mycobacterium tuberculosis protein kinase G.

Wittwer M, Dames SA.

Protein Expr Purif. 2015 Jul;111:68-74. doi: 10.1016/j.pep.2015.03.015. Epub 2015 Apr 1.

PMID:
25839674
12.

One short cysteine-rich sequence pattern - two different disulfide-bonded structures - a molecular dynamics simulation study.

Dames SA.

J Pept Sci. 2015 Jun;21(6):480-94. doi: 10.1002/psc.2765. Epub 2015 Mar 17.

PMID:
25781269
13.

Subtype-specific modulation of estrogen receptor-coactivator interaction by phosphorylation.

Tharun IM, Nieto L, Haase C, Scheepstra M, Balk M, Möcklinghoff S, Adriaens W, Dames SA, Brunsveld L.

ACS Chem Biol. 2015 Feb 20;10(2):475-84. doi: 10.1021/cb5007097. Epub 2014 Nov 11.

PMID:
25386784
14.

Characterization of the immersion properties of the peripheral membrane anchor of the FATC domain of the kinase "target of rapamycin" by NMR, oriented CD spectroscopy, and MD simulations.

Sommer LA, Janke JJ, Bennett WF, Bürck J, Ulrich AS, Tieleman DP, Dames SA.

J Phys Chem B. 2014 May 8;118(18):4817-31. doi: 10.1021/jp501533d. Epub 2014 Apr 25.

PMID:
24725177
15.
16.
17.
18.

The FKBP-rapamycin binding domain of human TOR undergoes strong conformational changes in the presence of membrane mimetics with and without the regulator phosphatidic acid.

Rodriguez Camargo DC, Link NM, Dames SA.

Biochemistry. 2012 Jun 19;51(24):4909-21. doi: 10.1021/bi3002133. Epub 2012 Jun 5.

PMID:
22620485
19.

Positional screening and NMR structure determination of side-chain-to-side-chain cyclized β3-peptides.

Vaz E, Dames SA, Geyer M, Brunsveld L.

Org Biomol Chem. 2012 Feb 21;10(7):1365-73. doi: 10.1039/c1ob06422c. Epub 2011 Dec 20.

PMID:
22183293
20.

Structure and dynamics of a stabilized coiled-coil domain in the P-TEFb regulator Hexim1.

Bigalke JM, Dames SA, Blankenfeldt W, Grzesiek S, Geyer M.

J Mol Biol. 2011 Dec 16;414(5):639-53. doi: 10.1016/j.jmb.2011.10.022. Epub 2011 Oct 18.

PMID:
22033481
21.

Structure, dynamics, lipid binding, and physiological relevance of the putative GTPase-binding domain of Dictyostelium formin C.

Dames SA, Junemann A, Sass HJ, Schönichen A, Stopschinski BE, Grzesiek S, Faix J, Geyer M.

J Biol Chem. 2011 Oct 21;286(42):36907-20. doi: 10.1074/jbc.M111.225052. Epub 2011 Aug 16.

22.

1H, 15N, and 13C assignments of the N-terminal activation domain of Dictyostelium discoideum Formin C.

Dames SA, Schönichen A, Geyer M.

Biomol NMR Assign. 2011 Apr;5(1):47-9. doi: 10.1007/s12104-010-9264-3. Epub 2010 Oct 7.

PMID:
20927614
23.

A flexible bipartite coiled coil structure is required for the interaction of Hexim1 with the P-TEFB subunit cyclin T1.

Schönichen A, Bigalke JM, Urbanke C, Grzesiek S, Dames SA, Geyer M.

Biochemistry. 2010 Apr 13;49(14):3083-91. doi: 10.1021/bi902072f.

PMID:
20210365
24.

Structural basis for the association of the redox-sensitive target of rapamycin FATC domain with membrane-mimetic micelles.

Dames SA.

J Biol Chem. 2010 Mar 5;285(10):7766-75. doi: 10.1074/jbc.M109.058404. Epub 2009 Dec 30.

25.

Next-generation sequencing: from basic research to diagnostics.

Voelkerding KV, Dames SA, Durtschi JD.

Clin Chem. 2009 Apr;55(4):641-58. doi: 10.1373/clinchem.2008.112789. Epub 2009 Feb 26. Review.

26.

Insights into the low adhesive capacity of human T-cadherin from the NMR structure of Its N-terminal extracellular domain.

Dames SA, Bang E, Haüssinger D, Ahrens T, Engel J, Grzesiek S.

J Biol Chem. 2008 Aug 22;283(34):23485-95. doi: 10.1074/jbc.M708335200. Epub 2008 Jun 10.

27.

A fast and simple method to prepare the FKBP-rapamycin binding domain of human target of rapamycin for NMR binding assays.

Dames SA.

Protein Expr Purif. 2008 May;59(1):31-7. doi: 10.1016/j.pep.2008.01.014. Epub 2008 Jan 26.

PMID:
18313330
28.

Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb.

Dames SA, Schönichen A, Schulte A, Barboric M, Peterlin BM, Grzesiek S, Geyer M.

Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14312-7. Epub 2007 Aug 27.

29.

1H, 13C, and 15N chemical shift assignments for the N-terminal extracellular domain of T-cadherin.

Bang E, Häussinger D, Stetefeld J, Ahrens T, Grzesiek S, Dames SA.

J Biomol NMR. 2007 Jun;38(2):179. Epub 2006 Dec 19. No abstract available.

PMID:
17180550
30.

Residual dipolar couplings in short peptides reveal systematic conformational preferences of individual amino acids.

Dames SA, Aregger R, Vajpai N, Bernado P, Blackledge M, Grzesiek S.

J Am Chem Soc. 2006 Oct 18;128(41):13508-14.

PMID:
17031964
31.

NMR assignment of the Cyclin T-binding domain of human Hexim1.

Dames SA, Schönichen A, Grzesiek S, Geyer M.

J Biomol NMR. 2006;36 Suppl 1:39. Epub 2006 May 23. No abstract available.

PMID:
16917728
32.

The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability.

Dames SA, Mulet JM, Rathgeb-Szabo K, Hall MN, Grzesiek S.

J Biol Chem. 2005 May 27;280(21):20558-64. Epub 2005 Mar 16.

33.

Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response.

Dames SA, Martinez-Yamout M, De Guzman RN, Dyson HJ, Wright PE.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5271-6.

34.

Use of high specific activity StarFire oligonucleotide probes to visualize low-abundance pre-mRNA splicing intermediates in S. pombe.

Behlke MA, Dames SA, McDonald WH, Gould KL, Devor EJ, Walder JA.

Biotechniques. 2000 Oct;29(4):892-7.

35.
36.

Contributions of the ionization states of acidic residues to the stability of the coiled coil domain of matrilin-1.

Dames SA, Kammerer RA, Moskau D, Engel J, Alexandrescu AT.

FEBS Lett. 1999 Mar 5;446(1):75-80.

37.

NMR structure of a parallel homotrimeric coiled coil.

Dames SA, Kammerer RA, Wiltscheck R, Engel J, Alexandrescu AT.

Nat Struct Biol. 1998 Aug;5(8):687-91.

PMID:
9699631
38.

Heteronuclear NMR assignments and secondary structure of the coiled coil trimerization domain from cartilage matrix protein in oxidized and reduced forms.

Wiltscheck R, Kammerer RA, Dames SA, Schulthess T, Blommers MJ, Engel J, Alexandrescu AT.

Protein Sci. 1997 Aug;6(8):1734-45.

40.

Characterization of Caenorhabditis elegans lectin-binding mutants.

Link CD, Silverman MA, Breen M, Watt KE, Dames SA.

Genetics. 1992 Aug;131(4):867-81.

Supplemental Content

Loading ...
Support Center