Sort by
Items per page

Send to

Choose Destination

Search results

Items: 46


Butyrogenic bacteria after acute graft-versus-host disease (GVHD) are associated with the development of steroid-refractory GVHD.

Golob JL, DeMeules MM, Loeffelholz T, Quinn ZZ, Dame MK, Silvestri SS, Wu MC, Schmidt TM, Fiedler TL, Hoostal MJ, Mielcarek M, Spence J, Pergam SA, Fredricks DN.

Blood Adv. 2019 Oct 8;3(19):2866-2869. doi: 10.1182/bloodadvances.2019000362. No abstract available.


Dietary polyunsaturated fatty acids modulate adipose secretome and is associated with changes in mammary epithelial stem cell self-renewal.

Hill EM, Esper RM, Sen A, Simon BR, Aslam MN, Jiang Y, Dame MK, McClintock SD, Colacino JA, Djuric Z, Wicha MS, Smith WL, Brenner DE.

J Nutr Biochem. 2019 Sep;71:45-53. doi: 10.1016/j.jnutbio.2019.05.007. Epub 2019 May 24.


Calcium-induced differentiation in normal human colonoid cultures: Cell-cell / cell-matrix adhesion, barrier formation and tissue integrity.

Attili D, McClintock SD, Rizvi AH, Pandya S, Rehman H, Nadeem DM, Richter A, Thomas D, Dame MK, Turgeon DK, Varani J, Aslam MN.

PLoS One. 2019 Apr 17;14(4):e0215122. doi: 10.1371/journal.pone.0215122. eCollection 2019.


A Method for Cryogenic Preservation of Human Biopsy Specimens and Subsequent Organoid Culture.

Tsai YH, Czerwinski M, Wu A, Dame MK, Attili D, Hill E, Colacino JA, Nowacki LM, Shroyer NF, Higgins PDR, Kao JY, Spence JR.

Cell Mol Gastroenterol Hepatol. 2018 May 30;6(2):218-222.e7. doi: 10.1016/j.jcmgh.2018.04.008. eCollection 2018. No abstract available.


In Vitro Porcine Colon Culture.

Costa MO, Hill JE, Dame MK, Harding JCS.

Methods Mol Biol. 2018;1817:185-195. doi: 10.1007/978-1-4939-8600-2_18.


Calcium-Induced Differentiation of Human Colon Adenomas in Colonoid Culture: Calcium Alone versus Calcium with Additional Trace Elements.

McClintock SD, Colacino JA, Attili D, Dame MK, Richter A, Reddy AR, Basrur V, Rizvi AH, Turgeon DK, Varani J, Aslam MN.

Cancer Prev Res (Phila). 2018 Jul;11(7):413-428. doi: 10.1158/1940-6207.CAPR-17-0308. Epub 2018 Apr 10.


Identification, isolation and characterization of human LGR5-positive colon adenoma cells.

Dame MK, Attili D, McClintock SD, Dedhia PH, Ouillette P, Hardt O, Chin AM, Xue X, Laliberte J, Katz EL, Newsome GM, Hill DR, Miller AJ, Tsai YH, Agorku D, Altheim CH, Bosio A, Simon B, Samuelson LC, Stoerker JA, Appelman HD, Varani J, Wicha MS, Brenner DE, Shah YM, Spence JR, Colacino JA.

Development. 2018 Mar 14;145(6). pii: dev153049. doi: 10.1242/dev.153049.


Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis.

Xue X, Ramakrishnan SK, Weisz K, Triner D, Xie L, Attili D, Pant A, Győrffy B, Zhan M, Carter-Su C, Hardiman KM, Wang TD, Dame MK, Varani J, Brenner D, Fearon ER, Shah YM.

Cell Metab. 2016 Sep 13;24(3):447-461. doi: 10.1016/j.cmet.2016.07.015. Epub 2016 Aug 18.


Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1.

Zhang H, Ramakrishnan SK, Triner D, Centofanti B, Maitra D, Győrffy B, Sebolt-Leopold JS, Dame MK, Varani J, Brenner DE, Fearon ER, Omary MB, Shah YM.

Sci Signal. 2015 Oct 6;8(397):ra98. doi: 10.1126/scisignal.aac5418.


MDI 301 suppresses myeloid leukemia cell growth in vitro and in vivo without the toxicity associated with all-trans retinoic acid therapy.

Aslam MN, McClintock S, Khan SP, Perone P, Allen R, Ouillette PD, Dame MK, Cheng JX, Kunkel SL, Varani J.

Anticancer Drugs. 2015 Aug;26(7):763-73. doi: 10.1097/CAD.0000000000000248.


Monoclonal antibodies specific for oncofetal antigen--immature laminin receptor protein: Effects on tumor growth and spread in two murine models.

McClintock SD, Warner RL, Ali S, Chekuri A, Dame MK, Attili D, Knibbs RK, Aslam MN, Sinkule J, Morgan AC, Barsoum A, Smith LB, Beer DG, Johnson KJ, Varani J.

Cancer Biol Ther. 2015;16(5):724-32. doi: 10.1080/15384047.2015.1026484.


Erlotinib-induced skin inflammation is IL-1 mediated in KC-Tie2 mice and human skin organ culture.

Ward NL, Bhagathavula N, Johnston A, Dawes SM, Fu W, Lambert S, Dame MK, Warner RL, Gudjonsson JE, Varani J, Elder JT.

J Invest Dermatol. 2015 Mar;135(3):910-913. doi: 10.1038/jid.2014.445. Epub 2014 Oct 13. No abstract available.


Human colonic crypts in culture: segregation of immunochemical markers in normal versus adenoma-derived.

Dame MK, Jiang Y, Appelman HD, Copley KD, McClintock SD, Aslam MN, Attili D, Elmunzer BJ, Brenner DE, Varani J, Turgeon DK.

Lab Invest. 2014 Feb;94(2):222-34. doi: 10.1038/labinvest.2013.145. Epub 2013 Dec 23.


A multimineral natural product from red marine algae reduces colon polyp formation in C57BL/6 mice.

Aslam MN, Bergin I, Naik M, Paruchuri T, Hampton A, Rehman M, Dame MK, Rush H, Varani J.

Nutr Cancer. 2012;64(7):1020-8. doi: 10.1080/01635581.2012.713160. Epub 2012 Oct 4.


Growth control in colon epithelial cells: gadolinium enhances calcium-mediated growth regulation.

Attili D, Jenkins B, Aslam MN, Dame MK, Varani J.

Biol Trace Elem Res. 2012 Dec;150(1-3):467-76. doi: 10.1007/s12011-012-9503-9. Epub 2012 Sep 19.


Stimulation of fibroblast proliferation by insoluble gadolinium salts.

Bleavins K, Perone P, Naik M, Rehman M, Aslam MN, Dame MK, Meshinchi S, Bhagavathula N, Varani J.

Biol Trace Elem Res. 2012 Feb;145(2):257-67. doi: 10.1007/s12011-011-9176-9. Epub 2011 Sep 1.


Fibroblast response to lanthanoid metal ion stimulation: potential contribution to fibrotic tissue injury.

Jenkins W, Perone P, Walker K, Bhagavathula N, Aslam MN, DaSilva M, Dame MK, Varani J.

Biol Trace Elem Res. 2011 Dec;144(1-3):621-35. doi: 10.1007/s12011-011-9041-x. Epub 2011 Apr 12.


Human colon tissue in organ culture: calcium and multi-mineral-induced mucosal differentiation.

Dame MK, Veerapaneni I, Bhagavathula N, Naik M, Varani J.

In Vitro Cell Dev Biol Anim. 2011 Jan;47(1):32-8. doi: 10.1007/s11626-010-9358-3. Epub 2010 Nov 20.


Fibroblast response to gadolinium: role for platelet-derived growth factor receptor.

Bhagavathula N, Dame MK, DaSilva M, Jenkins W, Aslam MN, Perone P, Varani J.

Invest Radiol. 2010 Dec;45(12):769-77. doi: 10.1097/RLI.0b013e3181e943d2.


Responses of human skin in organ culture and human skin fibroblasts to a gadolinium-based MRI contrast agent: comparison of skin from patients with end-stage renal disease and skin from healthy subjects.

DaSilva M, O'Brien Deming M, Fligiel SE, Dame MK, Johnson KJ, Swartz RD, Varani J.

Invest Radiol. 2010 Nov;45(11):733-9. doi: 10.1097/RLI.0b013e3181e9436b.


Collagenolytic activity is suppressed in organ-cultured human skin exposed to a gadolinium-based MRI contrast agent.

Perone PA, Weber SL, DaSilva M, Paruchuri T, Bhagavathula N, Aslam MN, Dame MK, Johnson KJ, Swartz RD, Varani J.

Invest Radiol. 2010 Jan;45(1):42-8. doi: 10.1097/RLI.0b013e3181bf95eb.


Human colon tissue in organ culture: preservation of normal and neoplastic characteristics.

Dame MK, Bhagavathula N, Mankey C, DaSilva M, Paruchuri T, Aslam MN, Varani J.

In Vitro Cell Dev Biol Anim. 2010 Feb;46(2):114-22. doi: 10.1007/s11626-009-9247-9.


Regulation of collagen turnover in human skin fibroblasts exposed to a gadolinium-based contrast agent.

Bhagavathula N, DaSilva M, Aslam MN, Dame MK, Warner RL, Xu Y, Fisher GJ, Johnson KJ, Swartz R, Varani J.

Invest Radiol. 2009 Aug;44(8):433-9. doi: 10.1097/RLI.0b013e3181a4d7e9.


The Göttingen minipig for assessment of retinoid efficacy in the skin: comparison of results from topically treated animals with results from organ-cultured skin.

Dame MK, Paruchuri T, DaSilva M, Bhagavathula N, Ridder W, Varani J.

In Vitro Cell Dev Biol Anim. 2009 Oct;45(9):551-7. doi: 10.1007/s11626-009-9221-6. Epub 2009 Jun 18.


Impaired keratinocyte function on matrix metalloproteinase-1 (MMP-1) damaged collagen.

Varani J, Perone P, Deming MO, Warner RL, Aslam MN, Bhagavathula N, Dame MK, Voorhees JJ.

Arch Dermatol Res. 2009 Aug;301(7):497-506. doi: 10.1007/s00403-009-0948-4. Epub 2009 Apr 8.


Recombinant collagen for animal product-free dextran microcarriers.

Dame MK, Varani J.

In Vitro Cell Dev Biol Anim. 2008 Nov-Dec;44(10):407-14. doi: 10.1007/s11626-008-9139-4. Epub 2008 Sep 25.


Establishment and characteristics of Gottingen minipig skin in organ culture and monolayer cell culture: relevance to drug safety testing.

Dame MK, Spahlinger DM, DaSilva M, Perone P, Dunstan R, Varani J.

In Vitro Cell Dev Biol Anim. 2008 Jul-Aug;44(7):245-52. doi: 10.1007/s11626-008-9091-3. Epub 2008 Jun 21.


Vascular tube formation on matrix metalloproteinase-1-damaged collagen.

Varani J, Perone P, Warner RL, Dame MK, Kang S, Fisher GJ, Voorhees JJ.

Br J Cancer. 2008 May 20;98(10):1646-52. doi: 10.1038/sj.bjc.6604357. Epub 2008 Apr 29.


Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation.

Varani J, Dame MK, Rittie L, Fligiel SE, Kang S, Fisher GJ, Voorhees JJ.

Am J Pathol. 2006 Jun;168(6):1861-8.


Reduced fibroblast interaction with intact collagen as a mechanism for depressed collagen synthesis in photodamaged skin.

Varani J, Schuger L, Dame MK, Leonard C, Fligiel SE, Kang S, Fisher GJ, Voorhees JJ.

J Invest Dermatol. 2004 Jun;122(6):1471-9.


A stepwise method for the isolation of endothelial cells and smooth muscle cells from individual canine coronary arteries.

Dame MK, Yu X, Garrido R, Bobrowski W, McDuffie JE, Murphy HS, Albassam M, Varani J.

In Vitro Cell Dev Biol Anim. 2003 Nov-Dec;39(10):402-6.


Differential expression of an alpha-galactosyl-containing trisaccharide on high- and low-malignant murine sarcoma cells: identification and regulation.

Varani J, Petryniak J, Takagaki M, Dame MK, Petryniak B, Goldstein IJ.

Clin Exp Metastasis. 2002;19(1):1-8.


Heparin-binding epidermal-growth-factor-like growth factor activation of keratinocyte ErbB receptors Mediates epidermal hyperplasia, a prominent side-effect of retinoid therapy.

Varani J, Zeigler M, Dame MK, Kang S, Fisher GJ, Voorhees JJ, Stoll SW, Elder JT.

J Invest Dermatol. 2001 Dec;117(6):1335-41.


Endothelial cell determinants of susceptibility to neutrophil-mediated killing.

Murphy HS, Warner RL, Bakopoulos N, Dame MK, Varani J, Ward PA.

Shock. 1999 Aug;12(2):111-7.


Characteristics of nonmalignant and malignant human prostate in organ culture.

Varani J, Dame MK, Wojno K, Schuger L, Johnson KJ.

Lab Invest. 1999 Jun;79(6):723-31.


Heterogeneity of vascular endothelial cells: differences in susceptibility to neutrophil-mediated injury.

Murphy HS, Bakopoulos N, Dame MK, Varani J, Ward PA.

Microvasc Res. 1998 Nov;56(3):203-11.


Deferoxamine interferes with adhesive functions of activated human neutrophils.

Varani J, Dame MK, Diaz M, Stoolman L.

Shock. 1996 Jun;5(6):395-401.


Age-dependent injury in human umbilical vein endothelial cells: relationship to apoptosis and correlation with a lack of A20 expression.

Varani J, Dame MK, Taylor CG, Sarma V, Merino R, Kunkel RG, Nunez G, Dixit VM.

Lab Invest. 1995 Dec;73(6):851-8.


Injury to adult human dermal microvascular endothelial cells in vitro.

Varani J, Dame MK.

Shock. 1995 Mar;3(3):179-83.


Thrombin induction of plasminogen activator inhibitor mRNA in human umbilical vein endothelial cells in culture.

Heaton JH, Dame MK, Gelehrter TD.

J Lab Clin Med. 1992 Aug;120(2):222-8.


Protection of human umbilical vein endothelial cells by glycine and structurally similar amino acids against calcium and hydrogen peroxide-induced lethal cell injury.

Weinberg JM, Varani J, Johnson KJ, Roeser NF, Dame MK, Davis JA, Venkatachalam MA.

Am J Pathol. 1992 Feb;140(2):457-71.


Role of endothelial-leukocyte adhesion molecule 1 (ELAM-1) in neutrophil-mediated lung injury in rats.

Mulligan MS, Varani J, Dame MK, Lane CL, Smith CW, Anderson DC, Ward PA.

J Clin Invest. 1991 Oct;88(4):1396-406.

Supplemental Content

Support Center