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Items: 1 to 50 of 179

1.

Pharmacological mechanisms of alcohol analgesic-like properties in mouse models of acute and chronic pain.

Neddenriep B, Bagdas D, Contreras KM, Ditre JW, Wolstenholme JT, Miles MF, Damaj MI.

Neuropharmacology. 2019 Sep 25;160:107793. doi: 10.1016/j.neuropharm.2019.107793. [Epub ahead of print]

PMID:
31562845
2.

C57BL/6 Substrain Differences in Pharmacological Effects after Acute and Repeated Nicotine Administration.

Akinola LS, Mckiver B, Toma W, Zhu AZX, Tyndale RF, Kumar V, Damaj MI.

Brain Sci. 2019 Sep 21;9(10). pii: E244. doi: 10.3390/brainsci9100244.

3.

Δ8 -Tetrahydrocannabivarin has potent anti-nicotine effects in multiple rodent models of nicotine dependence.

Xi ZX, Muldoon P, Wang XF, Bi GH, Damaj MI, Lichtman AH, Pertwee RG, Gardner EL.

Br J Pharmacol. 2019 Aug 27. doi: 10.1111/bph.14844. [Epub ahead of print]

PMID:
31454413
4.

Adolescent but not adult ethanol binge drinking modulates ethanol behavioral effects in mice later in life.

Younis RM, Wolstenholme JT, Bagdas D, Bettinger JC, Miles MF, Damaj MI.

Pharmacol Biochem Behav. 2019 Sep;184:172740. doi: 10.1016/j.pbb.2019.172740. Epub 2019 Jul 18.

PMID:
31326461
5.

Impact of modulation of the α7 nicotinic acetylcholine receptor on nicotine reward in the mouse conditioned place preference test.

Jackson A, Alkhlaif Y, Papke RL, Brunzell DH, Damaj MI.

Psychopharmacology (Berl). 2019 Jul 13. doi: 10.1007/s00213-019-05331-y. [Epub ahead of print]

PMID:
31302720
6.

The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal.

Toma W, Kyte SL, Bagdas D, Jackson A, Meade JA, Rahman F, Chen ZJ, Del Fabbro E, Cantwell L, Kulkarni A, Thakur GA, Papke RL, Bigbee JW, Gewirtz DA, Damaj MI.

Exp Neurol. 2019 Oct;320:113010. doi: 10.1016/j.expneurol.2019.113010. Epub 2019 Jul 9.

PMID:
31299179
7.

Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes.

Chen J, Loukola A, Gillespie NA, Peterson R, Jia P, Riley B, Maes H, Dick DM, Kendler KS, Damaj MI, Miles MF, Zhao Z, Li MD, Vink JM, Minica CC, Willemsen G, Boomsma DI, Qaiser B, Madden PAF, Korhonen T, Jousilahti P, Hällfors J, Gelernter J, Kranzler HR, Sherva R, Farrer L, Maher B, Vanyukov M, Taylor M, Ware JJ, Munafò MR, Lutz SM, Hokanson JE, Gu F, Landi MT, Caporaso NE, Hancock DB, Gaddis NC, Baker TB, Bierut LJ, Johnson EO, Chenoweth M, Lerman C, Tyndale R, Kaprio J, Chen X.

Nicotine Tob Res. 2019 Jul 11. pii: ntz099. doi: 10.1093/ntr/ntz099. [Epub ahead of print]

PMID:
31294817
8.

Assessing nicotine dependence using an oral nicotine free-choice paradigm in mice.

Bagdas D, Diester CM, Riley J, Carper M, Alkhlaif Y, AlOmari D, Alayoubi H, Poklis JL, Damaj MI.

Neuropharmacology. 2019 Oct;157:107669. doi: 10.1016/j.neuropharm.2019.107669. Epub 2019 Jun 18.

PMID:
31220484
9.

The β3 subunit of the nicotinic acetylcholine receptor is required for nicotine withdrawal-induced affective but not physical signs or nicotine reward in mice.

Jackson AB, Toma W, Contreras KM, Alkhlaif Y, Damaj MI.

Pharmacol Biochem Behav. 2019 Aug;183:1-5. doi: 10.1016/j.pbb.2019.05.003. Epub 2019 May 27.

PMID:
31145916
10.

Neuropathic insult increases the responsiveness to acetic acid in mice.

Gurdap CO, Markwalter PS Jr, Neddenriep B, Bagdas D, Damaj MI.

Behav Pharmacol. 2019 Sep;30(6):534-537. doi: 10.1097/FBP.0000000000000486.

PMID:
31033524
11.

Impact of menthol on oral nicotine consumption in female and male Sprague Dawley rats.

Bagdas D, Cam B, Gul Z, Scott MM, Tyndale RF, Buyukuysal RL, Damaj MI, Gurun MS.

Nicotine Tob Res. 2019 Feb 11. doi: 10.1093/ntr/ntz019. [Epub ahead of print]

PMID:
30753589
12.

Blockade of nicotinic acetylcholine receptor enhances the responsiveness to bupropion in the mouse forced swim test.

Bagdas D, AlSharari S, Roni MA, Campbell VC, Muldoon PP, Carroll FI, Damaj MI.

Behav Brain Res. 2019 Mar 15;360:262-269. doi: 10.1016/j.bbr.2018.12.027. Epub 2018 Dec 12.

PMID:
30552947
13.

B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation.

Garai S, Raja KS, Papke RL, Deschamps JR, Damaj MI, Thakur GA.

ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148. doi: 10.1021/acsmedchemlett.8b00407. eCollection 2018 Nov 8.

PMID:
30429960
14.

Neuronal nicotinic acetylcholine receptors mediate ∆9 -THC dependence: Mouse and human studies.

Donvito G, Muldoon PP, Jackson KJ, Ahmad U, Zaveri NT, McIntosh JM, Chen X, Lichtman AH, Damaj MI.

Addict Biol. 2018 Oct 31. doi: 10.1111/adb.12691. [Epub ahead of print]

PMID:
30378732
15.

Early adolescent nicotine exposure affects later-life hippocampal mu-opioid receptors activity and morphine reward but not physical dependence in male mice.

Kota D, Alajaji M, Bagdas D, Selley DE, Sim-Selley LJ, Damaj MI.

Pharmacol Biochem Behav. 2018 Oct;173:58-64. doi: 10.1016/j.pbb.2018.08.006. Epub 2018 Aug 17.

16.

The Antinociceptive and Anti-Inflammatory Properties of the α7 nAChR Weak Partial Agonist p-CF3 N,N-diethyl-N'-phenylpiperazine.

Quadri M, Bagdas D, Toma W, Stokes C, Horenstein NA, Damaj MI, Papke RL.

J Pharmacol Exp Ther. 2018 Nov;367(2):203-214. doi: 10.1124/jpet.118.249904. Epub 2018 Aug 15.

PMID:
30111636
17.

Knockout of alpha 5 nicotinic acetylcholine receptors subunit alters ethanol-mediated behavioral effects and reward in mice.

Dawson A, Wolstenholme JT, Roni MA, Campbell VC, Jackson A, Slater C, Bagdas D, Perez EE, Bettinger JC, De Biasi M, Miles MF, Damaj MI.

Neuropharmacology. 2018 Aug;138:341-348. doi: 10.1016/j.neuropharm.2018.06.031. Epub 2018 Jun 23.

18.

Reduced intraepidermal nerve fibre density, glial activation, and sensory changes in HIV type-1 Tat-expressing female mice: involvement of Tat during early stages of HIV-associated painful sensory neuropathy.

Wodarski R, Bagdas D, Paris JJ, Pheby T, Toma W, Xu R, Damaj MI, Knapp PE, Rice ASC, Hauser KF.

Pain Rep. 2018 May 14;3(3):e654. doi: 10.1097/PR9.0000000000000654. eCollection 2018 May.

19.

New insights on the effects of varenicline on nicotine reward, withdrawal and hyperalgesia in mice.

Bagdas D, Alkhlaif Y, Jackson A, Carroll FI, Ditre JW, Damaj MI.

Neuropharmacology. 2018 Aug;138:72-79. doi: 10.1016/j.neuropharm.2018.05.025. Epub 2018 May 21.

20.

Effect of nicotine and alpha-7 nicotinic modulators on visceral pain-induced conditioned place aversion in mice.

Bagdas D, Meade JA, Alkhlaif Y, Muldoon PP, Carroll FI, Damaj MI.

Eur J Pain. 2018 Apr 10. doi: 10.1002/ejp.1231. [Epub ahead of print]

21.

N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice.

Donvito G, Piscitelli F, Muldoon P, Jackson A, Vitale RM, D'Aniello E, Giordano C, Ignatowska-Jankowska BM, Mustafa MA, Guida F, Petrie GN, Parker L, Smoum R, Sim-Selley L, Maione S, Lichtman AH, Damaj MI, Di Marzo V, Mechoulam R.

Neuropharmacology. 2019 Apr;148:320-331. doi: 10.1016/j.neuropharm.2018.03.020. Epub 2018 Mar 19.

PMID:
29567093
22.

Pharmacological modulation of the α7 nicotinic acetylcholine receptor in a mouse model of mecamylamine-precipitated nicotine withdrawal.

Jackson A, Papke RL, Damaj MI.

Psychopharmacology (Berl). 2018 Jul;235(7):1897-1905. doi: 10.1007/s00213-018-4879-7. Epub 2018 Mar 16.

23.

Monoacylglycerol Lipase Inhibitors Reverse Paclitaxel-Induced Nociceptive Behavior and Proinflammatory Markers in a Mouse Model of Chemotherapy-Induced Neuropathy.

Curry ZA, Wilkerson JL, Bagdas D, Kyte SL, Patel N, Donvito G, Mustafa MA, Poklis JL, Niphakis MJ, Hsu KL, Cravatt BF, Gewirtz DA, Damaj MI, Lichtman AH.

J Pharmacol Exp Ther. 2018 Jul;366(1):169-183. doi: 10.1124/jpet.117.245704. Epub 2018 Mar 14.

24.

Nicotinic acetylcholine receptors (nAChRs) are expressed in Trpm5 positive taste receptor cells (TRCs).

Qian J, Mummalaneni S, Grider JR, Damaj MI, Lyall V.

PLoS One. 2018 Jan 2;13(1):e0190465. doi: 10.1371/journal.pone.0190465. eCollection 2018.

25.

Basic Science and Public Policy: Informed Regulation for Nicotine and Tobacco Products.

Fowler CD, Gipson CD, Kleykamp BA, Rupprecht LE, Harrell PT, Rees VW, Gould TJ, Oliver J, Bagdas D, Damaj MI, Schmidt HD, Duncan A, De Biasi M; Basic Science Network (BSN) of the Society for Research on Nicotine and Tobacco (SRNT).

Nicotine Tob Res. 2018 Jun 7;20(7):789-799. doi: 10.1093/ntr/ntx175. Review.

26.

Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN.

Kyte SL, Toma W, Bagdas D, Meade JA, Schurman LD, Lichtman AH, Chen ZJ, Del Fabbro E, Fang X, Bigbee JW, Damaj MI, Gewirtz DA.

J Pharmacol Exp Ther. 2018 Jan;364(1):110-119. doi: 10.1124/jpet.117.243972. Epub 2017 Oct 17.

27.

New Insights on Neuronal Nicotinic Acetylcholine Receptors as Targets for Pain and Inflammation: A Focus on α7 nAChRs.

Bagdas D, Gurun MS, Flood P, Papke RL, Damaj MI.

Curr Neuropharmacol. 2018;16(4):415-425. doi: 10.2174/1570159X15666170818102108. Review.

28.

Allosteric modulation of α4β2* nicotinic acetylcholine receptors: Desformylflustrabromine potentiates antiallodynic response of nicotine in a mouse model of neuropathic pain.

Bagdas D, Ergun D, Jackson A, Toma W, Schulte MK, Damaj MI.

Eur J Pain. 2018 Jan;22(1):84-93. doi: 10.1002/ejp.1092. Epub 2017 Aug 14.

PMID:
28809075
29.

Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice.

Owens RA, Mustafa MA, Ignatowska-Jankowska BM, Damaj MI, Beardsley PM, Wiley JL, Niphakis MJ, Cravatt BF, Lichtman AH.

Neuropharmacology. 2017 Oct;125:80-86. doi: 10.1016/j.neuropharm.2017.06.032. Epub 2017 Jun 30.

30.

Persistent activation of α7 nicotinic ACh receptors associated with stable induction of different desensitized states.

Papke RL, Stokes C, Damaj MI, Thakur GA, Manther K, Treinin M, Bagdas D, Kulkarni AR, Horenstein NA.

Br J Pharmacol. 2018 Jun;175(11):1838-1854. doi: 10.1111/bph.13851. Epub 2017 Jun 8.

31.

In vivo interactions between α7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α: Implication for nicotine dependence.

Jackson A, Bagdas D, Muldoon PP, Lichtman AH, Carroll FI, Greenwald M, Miles MF, Damaj MI.

Neuropharmacology. 2017 May 15;118:38-45. doi: 10.1016/j.neuropharm.2017.03.005. Epub 2017 Mar 7.

32.

Effects of paclitaxel on the development of neuropathy and affective behaviors in the mouse.

Toma W, Kyte SL, Bagdas D, Alkhlaif Y, Alsharari SD, Lichtman AH, Chen ZJ, Del Fabbro E, Bigbee JW, Gewirtz DA, Damaj MI.

Neuropharmacology. 2017 May 1;117:305-315. doi: 10.1016/j.neuropharm.2017.02.020. Epub 2017 Feb 22.

33.

Effects of Nicotine Metabolites on Nicotine Withdrawal Behaviors in Mice.

Elhassan S, Bagdas D, Damaj MI.

Nicotine Tob Res. 2017 Jun 1;19(6):763-766. doi: 10.1093/ntr/ntx045.

34.

Sex Differences and Drug Dose Influence the Role of the α7 Nicotinic Acetylcholine Receptor in the Mouse Dextran Sodium Sulfate-Induced Colitis Model.

AlSharari SD, Bagdas D, Akbarali HI, Lichtman PA, Raborn ES, Cabral GA, Carroll FI, McGee EA, Damaj MI.

Nicotine Tob Res. 2017 Apr 1;19(4):460-468. doi: 10.1093/ntr/ntw245.

PMID:
27639096
35.

Palmitoylethanolamide Reverses Paclitaxel-Induced Allodynia in Mice.

Donvito G, Wilkerson JL, Damaj MI, Lichtman AH.

J Pharmacol Exp Ther. 2016 Nov;359(2):310-318. Epub 2016 Sep 8.

36.

Synthesis, Nicotinic Acetylcholine Receptor Binding, and in Vitro and in Vivo Pharmacological Properties of 2'-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogues.

Ondachi PW, Castro AH, Sherman B, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI.

ACS Chem Neurosci. 2017 Jan 18;8(1):115-127. doi: 10.1021/acschemneuro.6b00252. Epub 2016 Oct 20.

PMID:
27726337
37.

Oxycodone physical dependence and its oral self-administration in C57BL/6J mice.

Enga RM, Jackson A, Damaj MI, Beardsley PM.

Eur J Pharmacol. 2016 Oct 15;789:75-80. doi: 10.1016/j.ejphar.2016.07.006. Epub 2016 Jul 5.

38.

The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain.

Bagdas D, Wilkerson JL, Kulkarni A, Toma W, AlSharari S, Gul Z, Lichtman AH, Papke RL, Thakur GA, Damaj MI.

Br J Pharmacol. 2016 Aug;173(16):2506-20. doi: 10.1111/bph.13528. Epub 2016 Jul 18.

39.

Synthesis, Nicotinic Acetylcholine Binding, and in Vitro and in Vivo Pharmacological Properties of 2'-Fluoro-(carbamoylpyridinyl)deschloroepibatidine Analogues.

Ondachi PW, Castro AH, Luetje CW, Wageman CR, Marks MJ, Damaj MI, Mascarella SW, Navarro HA, Carroll FI.

ACS Chem Neurosci. 2016 Jul 20;7(7):1004-12. doi: 10.1021/acschemneuro.6b00107. Epub 2016 May 19.

PMID:
27166021
40.

Enhanced Sensitivity of α3β4 Nicotinic Receptors in Enteric Neurons after Long-Term Morphine: Implication for Opioid-Induced Constipation.

Gade AR, Kang M, Khan F, Grider JR, Damaj MI, Dewey WL, Akbarali HI.

J Pharmacol Exp Ther. 2016 Jun;357(3):520-8. doi: 10.1124/jpet.116.233304. Epub 2016 Apr 11.

41.

Diacylglycerol lipase β inhibition reverses nociceptive behaviour in mouse models of inflammatory and neuropathic pain.

Wilkerson JL, Ghosh S, Bagdas D, Mason BL, Crowe MS, Hsu KL, Wise LE, Kinsey SG, Damaj MI, Cravatt BF, Lichtman AH.

Br J Pharmacol. 2016 May;173(10):1678-92. doi: 10.1111/bph.13469. Epub 2016 Apr 8.

42.

Early adolescent nicotine exposure affects later-life cocaine reward in mice.

Alajaji M, Lazenka MF, Kota D, Wise LE, Younis RM, Carroll FI, Levine A, Selley DE, Sim-Selley LJ, Damaj MI.

Neuropharmacology. 2016 Jun;105:308-317. doi: 10.1016/j.neuropharm.2016.01.032. Epub 2016 Jan 22.

PMID:
26808314
43.

N-acetylcysteine decreased nicotine reward-like properties and withdrawal in mice.

Bowers MS, Jackson A, Maldoon PP, Damaj MI.

Psychopharmacology (Berl). 2016 Mar;233(6):995-1003. doi: 10.1007/s00213-015-4179-4. Epub 2015 Dec 17.

44.

Expression and pharmacological modulation of visceral pain-induced conditioned place aversion in mice.

Bagdas D, Muldoon PP, AlSharari S, Carroll FI, Negus SS, Damaj MI.

Neuropharmacology. 2016 Mar;102:236-43. doi: 10.1016/j.neuropharm.2015.11.024. Epub 2015 Nov 27.

45.

Effects of Menthol on Nicotine Pharmacokinetic, Pharmacology and Dependence in Mice.

Alsharari SD, King JR, Nordman JC, Muldoon PP, Jackson A, Zhu AZ, Tyndale RF, Kabbani N, Damaj MI.

PLoS One. 2015 Sep 10;10(9):e0137070. doi: 10.1371/journal.pone.0137070. eCollection 2015.

46.

Neuronal calcium/calmodulin-dependent protein kinase II mediates nicotine reward in the conditioned place preference test in mice.

Jackson KJ, Muldoon PP, Walters C, Damaj MI.

Behav Pharmacol. 2016 Feb;27(1):50-6. doi: 10.1097/FBP.0000000000000189.

47.

The Antinociceptive and Antiinflammatory Properties of 3-furan-2-yl-N-p-tolyl-acrylamide, a Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptors in Mice.

Bagdas D, Targowska-Duda KM, López JJ, Perez EG, Arias HR, Damaj MI.

Anesth Analg. 2015 Nov;121(5):1369-77. doi: 10.1213/ANE.0000000000000902.

48.

Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3'-(substituted pyridinyl)-deschloroepibatidine analogs.

Ondachi PW, Ye Z, Castro AH, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI.

Bioorg Med Chem. 2015 Sep 1;23(17):5693-701. doi: 10.1016/j.bmc.2015.07.021. Epub 2015 Jul 17.

49.

Effects of orally-bioavailable short-acting kappa opioid receptor-selective antagonist LY2456302 on nicotine withdrawal in mice.

Jackson KJ, Jackson A, Carroll FI, Damaj MI.

Neuropharmacology. 2015 Oct;97:270-4. doi: 10.1016/j.neuropharm.2015.05.023. Epub 2015 Jun 1.

50.

The role of alpha5 nicotinic acetylcholine receptors in mouse models of chronic inflammatory and neuropathic pain.

Bagdas D, AlSharari SD, Freitas K, Tracy M, Damaj MI.

Biochem Pharmacol. 2015 Oct 15;97(4):590-600. doi: 10.1016/j.bcp.2015.04.013. Epub 2015 Apr 28.

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