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Serum lipoprotein(a) is not modified by interleukin-6 receptor antagonism or associated with inflammation in non-ST-elevation myocardial infarction.

Ueland T, Kleveland O, Michelsen AE, Wiseth R, Damås JK, Holven KB, Aukrust P, Gullestad L, Yndestad A, Halvorsen B.

Int J Cardiol. 2018 Jun 27. pii: S0167-5273(18)32258-7. doi: 10.1016/j.ijcard.2018.06.093. [Epub ahead of print]


Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction.

Kleveland O, Ueland T, Kunszt G, Bratlie M, Yndestad A, Broch K, Holte E, Ryan L, Amundsen BH, Bendz B, Aakhus S, Espevik T, Halvorsen B, Mollnes TE, Wiseth R, Gullestad L, Aukrust P, Damås JK.

Int J Cardiol. 2018 Jun 29. pii: S0167-5273(17)35500-6. doi: 10.1016/j.ijcard.2018.04.136. [Epub ahead of print]


Anxiety and depression symptoms in a general population and future risk of bloodstream infection. The HUNT Study.

Askim Å, Gustad LT, Paulsen J, Reitan SK, Mehl A, Mohus RM, Dewan A, Damås JK, Solligård E, Åsvold BO.

Psychosom Med. 2018 Jun 19. doi: 10.1097/PSY.0000000000000619. [Epub ahead of print]


Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn's disease.

Thorsvik S, Bakke I, van Beelen Granlund A, Røyset ES, Damås JK, Østvik AE, Sandvik AK.

Cell Tissue Res. 2018 Jun 5. doi: 10.1007/s00441-018-2860-8. [Epub ahead of print]


Transcapillary fluid flux and inflammatory response during neonatal therapeutic hypothermia: an open, longitudinal, observational study.

Guthe HJT, Nedrebø T, Damås JK, Wiig H, Berg A.

BMC Pediatr. 2018 Feb 23;18(1):82. doi: 10.1186/s12887-018-1020-3.


Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study.

Langeland H, Bergum D, Løberg M, Bjørnstad K, Damås JK, Mollnes TE, Skjærvold NK, Klepstad P.

JMIR Res Protoc. 2018 Jan 19;7(1):e17. doi: 10.2196/resprot.8558.


SOFA criteria predict infection-related in-hospital mortality in ICU patients better than SIRS criteria and the qSOFA score.

Solligård E, Damås JK.

Evid Based Med. 2017 Dec;22(6):211. doi: 10.1136/ebmed-2017-110727. Epub 2017 Nov 10. No abstract available.


Toll-Like Receptor 8 Is a Major Sensor of Group B Streptococcus But Not Escherichia coli in Human Primary Monocytes and Macrophages.

Ehrnström B, Beckwith KS, Yurchenko M, Moen SH, Kojen JF, Lentini G, Teti G, Damås JK, Espevik T, Stenvik J.

Front Immunol. 2017 Oct 3;8:1243. doi: 10.3389/fimmu.2017.01243. eCollection 2017.


Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation.

Bakke SS, Aune MH, Niyonzima N, Pilely K, Ryan L, Skjelland M, Garred P, Aukrust P, Halvorsen B, Latz E, Damås JK, Mollnes TE, Espevik T.

J Immunol. 2017 Oct 15;199(8):2910-2920. doi: 10.4049/jimmunol.1700302. Epub 2017 Aug 30.


N-3 PUFAs induce inflammatory tolerance by formation of KEAP1-containing SQSTM1/p62-bodies and activation of NFE2L2.

Mildenberger J, Johansson I, Sergin I, Kjøbli E, Damås JK, Razani B, Flo TH, Bjørkøy G.

Autophagy. 2017 Oct 3;13(10):1664-1678. doi: 10.1080/15548627.2017.1345411. Epub 2017 Aug 18.


Bronchial microdialysis monitoring of inflammatory response in open abdominal aortic aneurysm repair; an observational study.

Tyvold SS, Dahl T, Dragsund S, Gunnes S, Lyng O, Damås JK, Aadahl P, Solligård E.

Physiol Rep. 2017 Jul;5(14). pii: e13348. doi: 10.14814/phy2.13348.


Erratum to: Trends in antimicrobial resistance and empiric antibiotic therapy of bloodstream infections at a general hospital in mid-Norway: a prospective observational study.

Mehl A, Åsvold BO, Kümmel A, Lydersen S, Paulsen J, Haugan I, Solligård E, Damås JK, Harthug S, Edna TH.

BMC Infect Dis. 2017 Jun 23;17(1):446. doi: 10.1186/s12879-017-2545-z. No abstract available.


Associations of obesity and lifestyle with the risk and mortality of bloodstream infection in a general population: a 15-year follow-up of 64 027 individuals in the HUNT Study.

Paulsen J, Askim Å, Mohus RM, Mehl A, Dewan A, Solligård E, Damås JK, Åsvold BO.

Int J Epidemiol. 2017 Oct 1;46(5):1573-1581. doi: 10.1093/ije/dyx091.


Monocyte/macrophage and T cell activation markers are not independently associated with MI risk in healthy individuals - results from the HUNT Study.

Ueland T, Laugsand LE, Vatten LJ, Janszky I, Platou C, Michelsen AE, Damås JK, Aukrust P, Åsvold BO.

Int J Cardiol. 2017 Sep 15;243:502-504. doi: 10.1016/j.ijcard.2017.05.106. Epub 2017 Jun 12.


Poor performance of quick-SOFA (qSOFA) score in predicting severe sepsis and mortality - a prospective study of patients admitted with infection to the emergency department.

Askim Å, Moser F, Gustad LT, Stene H, Gundersen M, Åsvold BO, Dale J, Bjørnsen LP, Damås JK, Solligård E.

Scand J Trauma Resusc Emerg Med. 2017 Jun 9;25(1):56. doi: 10.1186/s13049-017-0399-4.


Effect of interleukin-6 inhibition on coronary microvascular and endothelial function in myocardial infarction.

Holte E, Kleveland O, Ueland T, Kunszt G, Bratlie M, Broch K, Michelsen AE, Bendz B, Amundsen BH, Aakhus S, Damås JK, Gullestad L, Aukrust P, Wiseth R.

Heart. 2017 Oct;103(19):1521-1527. doi: 10.1136/heartjnl-2016-310875. Epub 2017 Apr 21.


Extracellular matrix markers and risk of myocardial infarction: The HUNT Study in Norway.

Ueland T, Laugsand LE, Vatten LJ, Janszky I, Platou C, Michelsen AE, Damås JK, Aukrust P, Åsvold BO.

Eur J Prev Cardiol. 2017 Jul;24(11):1161-1167. doi: 10.1177/2047487317703826. Epub 2017 Apr 21.


Burden of bloodstream infection in an area of Mid-Norway 2002-2013: a prospective population-based observational study.

Mehl A, Åsvold BO, Lydersen S, Paulsen J, Solligård E, Damås JK, Harthug S, Edna TH.

BMC Infect Dis. 2017 Mar 11;17(1):205. doi: 10.1186/s12879-017-2291-2.


Trends in antimicrobial resistance and empiric antibiotic therapy of bloodstream infections at a general hospital in Mid-Norway: a prospective observational study.

Mehl A, Åsvold BO, Kümmel A, Lydersen S, Paulsen J, Haugan I, Solligård E, Damås JK, Harthug S, Edna TH.

BMC Infect Dis. 2017 Feb 2;17(1):116. doi: 10.1186/s12879-017-2210-6. Erratum in: BMC Infect Dis. 2017 Jun 23;17 (1):446.


Fecal neutrophil gelatinase-associated lipocalin as a biomarker for inflammatory bowel disease.

Thorsvik S, Damås JK, Granlund AV, Flo TH, Bergh K, Østvik AE, Sandvik AK.

J Gastroenterol Hepatol. 2017 Jan;32(1):128-135. doi: 10.1111/jgh.13598.


Early identification of sepsis in hospital inpatients by ward nurses increases 30-day survival.

Torsvik M, Gustad LT, Mehl A, Bangstad IL, Vinje LJ, Damås JK, Solligård E.

Crit Care. 2016 Aug 5;20(1):244. doi: 10.1186/s13054-016-1423-1.


Epidemiology and outcome of sepsis in adult patients with Streptococcus pneumoniae infection in a Norwegian county 1993-2011: an observational study.

Askim Å, Mehl A, Paulsen J, DeWan AT, Vestrheim DF, Åsvold BO, Damås JK, Solligård E.

BMC Infect Dis. 2016 May 23;16:223. doi: 10.1186/s12879-016-1553-8.


Effect of a single dose of the interleukin-6 receptor antagonist tocilizumab on inflammation and troponin T release in patients with non-ST-elevation myocardial infarction: a double-blind, randomized, placebo-controlled phase 2 trial.

Kleveland O, Kunszt G, Bratlie M, Ueland T, Broch K, Holte E, Michelsen AE, Bendz B, Amundsen BH, Espevik T, Aakhus S, Damås JK, Aukrust P, Wiseth R, Gullestad L.

Eur Heart J. 2016 Aug 7;37(30):2406-13. doi: 10.1093/eurheartj/ehw171. Epub 2016 May 8.


The Impact of Infectious Disease Specialist Consultation for Staphylococcus aureus Bloodstream Infections: A Systematic Review.

Paulsen J, Solligård E, Damås JK, DeWan A, Åsvold BO, Bracken MB.

Open Forum Infect Dis. 2016 Mar 1;3(2):ofw048. doi: 10.1093/ofid/ofw048. eCollection 2016 Mar. Review.


Low levels of short- and medium-chain acylcarnitines in HIV-infected patients.

Waagsbø B, Svardal A, Ueland T, Landrø L, Øktedalen O, Berge RK, Flo TH, Aukrust P, Damås JK.

Eur J Clin Invest. 2016 May;46(5):408-17. doi: 10.1111/eci.12609. Epub 2016 Mar 7.


Hepatitis C reinfection after sustained virological response.

Midgard H, Bjøro B, Mæland A, Konopski Z, Kileng H, Damås JK, Paulsen J, Heggelund L, Sandvei PK, Ringstad JO, Karlsen LN, Stene-Johansen K, Pettersson JH, Dorenberg DH, Dalgard O.

J Hepatol. 2016 May;64(5):1020-1026. doi: 10.1016/j.jhep.2016.01.001. Epub 2016 Jan 11.


Soluble CXCL16 and risk of myocardial infarction: The HUNT study in Norway.

Laugsand LE, Åsvold BO, Vatten LJ, Janszky I, Platou C, Michelsen AE, Arain F, Damås JK, Aukrust P, Ueland T.

Atherosclerosis. 2016 Jan;244:188-94. doi: 10.1016/j.atherosclerosis.2015.11.022. Epub 2015 Nov 25.


Expression of CCL20 and Its Corresponding Receptor CCR6 Is Enhanced in Active Inflammatory Bowel Disease, and TLR3 Mediates CCL20 Expression in Colonic Epithelial Cells.

Skovdahl HK, Granlund Av, Østvik AE, Bruland T, Bakke I, Torp SH, Damås JK, Sandvik AK.

PLoS One. 2015 Nov 4;10(11):e0141710. doi: 10.1371/journal.pone.0141710. eCollection 2015.


Keap1 regulates inflammatory signaling in Mycobacterium avium-infected human macrophages.

Awuh JA, Haug M, Mildenberger J, Marstad A, Do CP, Louet C, Stenvik J, Steigedal M, Damås JK, Halaas Ø, Flo TH.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4272-80. doi: 10.1073/pnas.1423449112. Epub 2015 Jul 20.


Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation.

Otterdal K, Haukeland JW, Yndestad A, Dahl TB, Holm S, Segers FM, Gladhaug IP, Konopski Z, Damås JK, Halvorsen B, Aukrust P.

Clin Transl Gastroenterol. 2015 Jul 2;6:e95. doi: 10.1038/ctg.2015.23.


Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation.

Niyonzima N, Samstad EO, Aune MH, Ryan L, Bakke SS, Rokstad AM, Wright SD, Damås JK, Mollnes TE, Latz E, Espevik T.

J Immunol. 2015 Jul 1;195(1):257-64. doi: 10.4049/jimmunol.1403044. Epub 2015 May 29.


Epidemiology and outcome of Staphylococcus aureus bloodstream infection and sepsis in a Norwegian county 1996-2011: an observational study.

Paulsen J, Mehl A, Askim Å, Solligård E, Åsvold BO, Damås JK.

BMC Infect Dis. 2015 Mar 4;15:116. doi: 10.1186/s12879-015-0849-4.


Genetic variants in the DNA repair gene NEIL3 and the risk of myocardial infarction in a nested case-control study. The HUNT Study.

Skarpengland T, Laugsand LE, Janszky I, Luna L, Halvorsen B, Platou CG, Wang W, Vatten LJ, Damås JK, Aukrust P, Bjørås M, Åsvold BO.

DNA Repair (Amst). 2015 Apr;28:21-7. doi: 10.1016/j.dnarep.2015.01.013. Epub 2015 Feb 2.


IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy.

Wergeland I, Pullar N, Assmus J, Ueland T, Tonby K, Feruglio S, Kvale D, Damås JK, Aukrust P, Mollnes TE, Dyrhol-Riise AM.

J Infect. 2015 Apr;70(4):381-91. doi: 10.1016/j.jinf.2014.12.019. Epub 2015 Jan 15.


Lipocalin 2 imparts selective pressure on bacterial growth in the bladder and is elevated in women with urinary tract infection.

Steigedal M, Marstad A, Haug M, Damås JK, Strong RK, Roberts PL, Himpsl SD, Stapleton A, Hooton TM, Mobley HL, Hawn TR, Flo TH.

J Immunol. 2014 Dec 15;193(12):6081-9. doi: 10.4049/jimmunol.1401528. Epub 2014 Nov 14.


Prior statin use and 90-day mortality in Gram-negative and Gram-positive bloodstream infection: a prospective observational study.

Mehl A, Harthug S, Lydersen S, Paulsen J, Åsvold BO, Solligård E, Damås JK, Edna TH.

Eur J Clin Microbiol Infect Dis. 2015 Mar;34(3):609-17. doi: 10.1007/s10096-014-2269-6. Epub 2014 Nov 6.


Increased endothelial and macrophage markers are associated with disease severity and mortality in scrub typhus.

Otterdal K, Janardhanan J, Astrup E, Ueland T, Prakash JA, Lekva T, Abraham OC, Thomas K, Damås JK, Mathews P, Mathai D, Aukrust P, Varghese GM.

J Infect. 2014 Nov;69(5):462-9. doi: 10.1016/j.jinf.2014.06.018. Epub 2014 Jul 1.


Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease.

Ostvik AE, Granlund Av, Gustafsson BI, Torp SH, Espevik T, Mollnes TE, Damås JK, Sandvik AK.

Inflamm Bowel Dis. 2014 Jun;20(6):995-1003. doi: 10.1097/MIB.0000000000000035.


Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.

Samstad EO, Niyonzima N, Nymo S, Aune MH, Ryan L, Bakke SS, Lappegård KT, Brekke OL, Lambris JD, Damås JK, Latz E, Mollnes TE, Espevik T.

J Immunol. 2014 Mar 15;192(6):2837-45. doi: 10.4049/jimmunol.1302484. Epub 2014 Feb 19.


Increased levels of CCR7 ligands in carotid atherosclerosis: different effects in macrophages and smooth muscle cells.

Halvorsen B, Dahl TB, Smedbakken LM, Singh A, Michelsen AE, Skjelland M, Krohg-Sørensen K, Russell D, Höpken UE, Lipp M, Damås JK, Holm S, Yndestad A, Biessen EA, Aukrust P.

Cardiovasc Res. 2014 Apr 1;102(1):148-56. doi: 10.1093/cvr/cvu036. Epub 2014 Feb 11.


Cytokine network in scrub typhus: high levels of interleukin-8 are associated with disease severity and mortality.

Astrup E, Janardhanan J, Otterdal K, Ueland T, Prakash JA, Lekva T, Strand ØA, Abraham OC, Thomas K, Damås JK, Mathews P, Mathai D, Aukrust P, Varghese GM.

PLoS Negl Trop Dis. 2014 Feb 6;8(2):e2648. doi: 10.1371/journal.pntd.0002648. eCollection 2014 Feb.


Increased expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental Rickettsia conorii infection.

Astrup E, Ranheim T, Damås JK, Davì G, Santilli F, Jensenius M, Vitale G, Aukrust P, Olano JP, Otterdal K.

BMC Infect Dis. 2014 Feb 9;14:70. doi: 10.1186/1471-2334-14-70.


Soluble markers of the Toll-like receptor 4 pathway differentiate between active and latent tuberculosis and are associated with treatment responses.

Feruglio SL, Trøseid M, Damås JK, Kvale D, Dyrhol-Riise AM.

PLoS One. 2013 Jul 16;8(7):e69896. doi: 10.1371/journal.pone.0069896. Print 2013.


Expression of Toll-like receptor-3 is enhanced in active inflammatory bowel disease and mediates the excessive release of lipocalin 2.

Østvik AE, Granlund AV, Torp SH, Flatberg A, Beisvåg V, Waldum HL, Flo TH, Espevik T, Damås JK, Sandvik AK.

Clin Exp Immunol. 2013 Sep;173(3):502-11. doi: 10.1111/cei.12136.


Whole genome gene expression meta-analysis of inflammatory bowel disease colon mucosa demonstrates lack of major differences between Crohn's disease and ulcerative colitis.

Granlund Av, Flatberg A, Østvik AE, Drozdov I, Gustafsson BI, Kidd M, Beisvag V, Torp SH, Waldum HL, Martinsen TC, Damås JK, Espevik T, Sandvik AK.

PLoS One. 2013;8(2):e56818. doi: 10.1371/journal.pone.0056818. Epub 2013 Feb 13.


Circulating levels of HMGB1 are correlated strongly with MD2 in HIV-infection: possible implication for TLR4-signalling and chronic immune activation.

Trøseid M, Lind A, Nowak P, Barqasho B, Heger B, Lygren I, Pedersen KK, Kanda T, Funaoka H, Damås JK, Kvale D.

Innate Immun. 2013 Jun;19(3):290-7. doi: 10.1177/1753425912461042. Epub 2012 Oct 15.


A complex interaction between Rickettsia conorii and Dickkopf-1--potential role in immune evasion mechanisms in endothelial cells.

Astrup E, Lekva T, Davì G, Otterdal K, Santilli F, Oie E, Halvorsen B, Damås JK, Raoult D, Vitale G, Olano JP, Ueland T, Aukrust P.

PLoS One. 2012;7(9):e43638. doi: 10.1371/journal.pone.0043638. Epub 2012 Sep 18.


[Risk of infection through use of selective immunomodulating drugs for rheumatoid arthritis].

Harboe E, Damås JK, Omdal R, Frøland SS, Sjursen H.

Tidsskr Nor Laegeforen. 2012 Sep 4;132(16):1867-71. doi: 10.4045/tidsskr.12.0180. Review. Norwegian.


Enhanced expression of CXCL10 in inflammatory bowel disease: potential role of mucosal Toll-like receptor 3 stimulation.

Ostvik AE, Granlund AV, Bugge M, Nilsen NJ, Torp SH, Waldum HL, Damås JK, Espevik T, Sandvik AK.

Inflamm Bowel Dis. 2013 Feb;19(2):265-74. doi: 10.1002/ibd.23034.


The homeostatic chemokine CCL21 predicts mortality and may play a pathogenic role in heart failure.

Yndestad A, Finsen AV, Ueland T, Husberg C, Dahl CP, Øie E, Vinge LE, Sjaastad I, Sandanger Ø, Ranheim T, Dickstein K, Kjekshus J, Damås JK, Fiane AE, Hilfiker-Kleiner D, Lipp M, Gullestad L, Christensen G, Aukrust P.

PLoS One. 2012;7(3):e33038. doi: 10.1371/journal.pone.0033038. Epub 2012 Mar 12.

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