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Microglia in Alzheimer's Disease: A Role for Ion Channels.

Thei L, Imm J, Kaisis E, Dallas ML, Kerrigan TL.

Front Neurosci. 2018 Sep 28;12:676. doi: 10.3389/fnins.2018.00676. eCollection 2018. Review.


Safety and immunogenicity of 15-valent pneumococcal conjugate vaccine (PCV15) in healthy infants.

Greenberg D, Hoover PA, Vesikari T, Peltier C, Hurley DC, McFetridge RD, Dallas M, Hartzel J, Marchese RD, Coller BG, Stek JE, Abeygunawardana C, Winters MA, MacNair JE, Pujar NS, Musey L.

Vaccine. 2018 Oct 29;36(45):6883-6891. doi: 10.1016/j.vaccine.2018.02.113. Epub 2018 Sep 21.


Immunotherapy Targeting HPV16/18 Generates Potent Immune Responses in HPV-Associated Head and Neck Cancer.

Aggarwal C, Cohen RB, Morrow MP, Kraynyak KA, Sylvester AJ, Knoblock DM, Bauml JM, Weinstein GS, Lin A, Boyer J, Sakata L, Tan S, Anton A, Dickerson K, Mangrolia D, Vang R, Dallas M, Oyola S, Duff S, Esser M, Kumar R, Weiner D, Csiki I, Bagarazzi ML.

Clin Cancer Res. 2019 Jan 1;25(1):110-124. doi: 10.1158/1078-0432.CCR-18-1763. Epub 2018 Sep 21.


Sucrose Nonfermenting 1-Related Protein Kinase 1 Phosphorylates a Geminivirus Rep Protein to Impair Viral Replication and Infection.

Shen W, Bobay BG, Greeley LA, Reyes MI, Rajabu CA, Blackburn RK, Dallas MB, Goshe MB, Ascencio-Ibáñez JT, Hanley-Bowdoin L.

Plant Physiol. 2018 Sep;178(1):372-389. doi: 10.1104/pp.18.00268. Epub 2018 Jul 13.


Effect of osteoporosis treatment agents on the cortical bone osteocyte microenvironment in adult estrogen-deficient, osteopenic rats.

Stern AR, Yao X, Wang Y, Berhe A, Dallas M, Johnson ML, Yao W, Kimmel DB, Lane NE.

Bone Rep. 2018 Feb 26;8:115-124. doi: 10.1016/j.bonr.2018.02.005. eCollection 2018 Jun.


Skeletal Response to Soluble Activin Receptor Type IIB in Mouse Models of Osteogenesis Imperfecta.

Jeong Y, Daghlas SA, Xie Y, Hulbert MA, Pfeiffer FM, Dallas MR, Omosule CL, Pearsall RS, Dallas SL, Phillips CL.

J Bone Miner Res. 2018 Oct;33(10):1760-1772. doi: 10.1002/jbmr.3473. Epub 2018 Jun 22.


Determination of Elastic Modulus in Mouse Bones Using a Nondestructive Micro-Indentation Technique Using Reference Point Indentation.

Thiagarajan G, Begonia MT, Dallas M, Lara-Castillo N, Scott JM, Johnson ML.

J Biomech Eng. 2018 Jul 1;140(7). doi: 10.1115/1.4039982.


Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies.

Maass C, Dallas M, LaBarge ME, Shockley M, Valdez J, Geishecker E, Stokes CL, Griffith LG, Cirit M.

Sci Rep. 2018 May 22;8(1):8015. doi: 10.1038/s41598-018-25971-y.


Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K+ channel Kv1.5.

Al-Owais MM, Hettiarachchi NT, Boyle JP, Scragg JL, Elies J, Dallas ML, Lippiat JD, Steele DS, Peers C.

Cell Death Dis. 2017 Nov 2;8(11):e3163. doi: 10.1038/cddis.2017.568.


Clinical and Immunologic Biomarkers for Histologic Regression of High-Grade Cervical Dysplasia and Clearance of HPV16 and HPV18 after Immunotherapy.

Morrow MP, Kraynyak KA, Sylvester AJ, Dallas M, Knoblock D, Boyer JD, Yan J, Vang R, Khan AS, Humeau L, Sardesai NY, Kim JJ, Plotkin S, Weiner DB, Trimble CL, Bagarazzi ML.

Clin Cancer Res. 2018 Jan 15;24(2):276-294. doi: 10.1158/1078-0432.CCR-17-2335. Epub 2017 Oct 30.


Degeneration of the osteocyte network in the C57BL/6 mouse model of aging.

Tiede-Lewis LM, Xie Y, Hulbert MA, Campos R, Dallas MR, Dusevich V, Bonewald LF, Dallas SL.

Aging (Albany NY). 2017 Oct 26;9(10):2190-2208. doi: 10.18632/aging.101308.


Using automated patch clamp electrophysiology platforms in pain-related ion channel research: insights from industry and academia.

Bell DC, Dallas ML.

Br J Pharmacol. 2018 Jun;175(12):2312-2321. doi: 10.1111/bph.13916. Epub 2017 Jul 18. Review.


Heme oxygenase-1 derived carbon monoxide suppresses Aβ1-42 toxicity in astrocytes.

Hettiarachchi NT, Boyle JP, Dallas ML, Al-Owais MM, Scragg JL, Peers C.

Cell Death Dis. 2017 Jun 15;8(6):e2884. doi: 10.1038/cddis.2017.276.


Comparison of strain measurement in the mouse forearm using subject-specific finite element models, strain gaging, and digital image correlation.

Begonia M, Dallas M, Johnson ML, Thiagarajan G.

Biomech Model Mechanobiol. 2017 Aug;16(4):1243-1253. doi: 10.1007/s10237-017-0885-7. Epub 2017 Feb 15.


Astrocytic transporters in Alzheimer's disease.

Ugbode C, Hu Y, Whalley B, Peers C, Rattray M, Dallas ML.

Biochem J. 2017 Feb 1;474(3):333-355. doi: 10.1042/BCJ20160505. Review.


Gaseous regulation of Ca(2+) homeostasis; for better or worse?

Dallas ML.

J Physiol. 2016 Aug 1;594(15):4117-8. doi: 10.1113/JP272693. No abstract available.


Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis.

Guo XZ, Dash P, Calverley M, Tomchuck S, Dallas MH, Thomas PG.

Mol Ther Methods Clin Dev. 2016 Jan 27;3:15054. doi: 10.1038/mtm.2015.54. eCollection 2016.


Treatment of hepatitis C in a pediatric patient using simeprevir and sofosbuvir immediately after an umbilical cord blood transplantation.

Thomas P, Santiago T, Dallas MH.

Bone Marrow Transplant. 2016 May;51(5):735-7. doi: 10.1038/bmt.2015.309. Epub 2016 Jan 11. No abstract available.


Modulation of Potassium Channels Inhibits Bunyavirus Infection.

Hover S, King B, Hall B, Loundras EA, Taqi H, Daly J, Dallas M, Peers C, Schnettler E, McKimmie C, Kohl A, Barr JN, Mankouri J.

J Biol Chem. 2016 Feb 12;291(7):3411-22. doi: 10.1074/jbc.M115.692673. Epub 2015 Dec 16.


Non-contact strain measurement in the mouse forearm loading model using digital image correlation (DIC).

Begonia MT, Dallas M, Vizcarra B, Liu Y, Johnson ML, Thiagarajan G.

Bone. 2015 Dec;81:593-601. doi: 10.1016/j.bone.2015.09.007. Epub 2015 Sep 24.


Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial.

Trimble CL, Morrow MP, Kraynyak KA, Shen X, Dallas M, Yan J, Edwards L, Parker RL, Denny L, Giffear M, Brown AS, Marcozzi-Pierce K, Shah D, Slager AM, Sylvester AJ, Khan A, Broderick KE, Juba RJ, Herring TA, Boyer J, Lee J, Sardesai NY, Weiner DB, Bagarazzi ML.

Lancet. 2015 Nov 21;386(10008):2078-2088. doi: 10.1016/S0140-6736(15)00239-1. Epub 2015 Sep 17.


GAL-021 and GAL-160 are Efficacious in Rat Models of Obstructive and Central Sleep Apnea and Inhibit BKCa in Isolated Rat Carotid Body Glomus Cells.

Dallas ML, Peers C, Golder FJ, Baby S, Gruber R, MacIntyre DE.

Adv Exp Med Biol. 2015;860:361-70. doi: 10.1007/978-3-319-18440-1_41.


Inhibition of T-type Ca2+ Channels by Hydrogen Sulfide.

Elies J, Scragg JL, Dallas ML, Huang D, Huang S, Boyle JP, Gamper N, Peers C.

Adv Exp Med Biol. 2015;860:353-60. doi: 10.1007/978-3-319-18440-1_40.


Heme Oxygenase-1 Influences Apoptosis via CO-mediated Inhibition of K+ Channels.

Al-Owais MM, Dallas ML, Boyle JP, Scragg JL, Peers C.

Adv Exp Med Biol. 2015;860:343-51. doi: 10.1007/978-3-319-18440-1_39.


T-Type Ca2+ Channel Regulation by CO: A Mechanism for Control of Cell Proliferation.

Duckles H, Al-Owais MM, Elies J, Johnson E, Boycott HE, Dallas ML, Porter KE, Boyle JP, Scragg JL, Peers C.

Adv Exp Med Biol. 2015;860:291-300. doi: 10.1007/978-3-319-18440-1_33.


Molecular Targets of Cannabidiol in Neurological Disorders.

Ibeas Bih C, Chen T, Nunn AV, Bazelot M, Dallas M, Whalley BJ.

Neurotherapeutics. 2015 Oct;12(4):699-730. doi: 10.1007/s13311-015-0377-3. Review.


Rapid memory T-cell reconstitution recapitulating CD45RA-depleted haploidentical transplant graft content in patients with hematologic malignancies.

Triplett BM, Shook DR, Eldridge P, Li Y, Kang G, Dallas M, Hartford C, Srinivasan A, Chan WK, Suwannasaen D, Inaba H, Merchant TE, Pui CH, Leung W.

Bone Marrow Transplant. 2015 Jul;50(7):1012. doi: 10.1038/bmt.2015.139. No abstract available.


Natural killer cell therapy in children with relapsed leukemia.

Rubnitz JE, Inaba H, Kang G, Gan K, Hartford C, Triplett BM, Dallas M, Shook D, Gruber T, Pui CH, Leung W.

Pediatr Blood Cancer. 2015 Aug;62(8):1468-72. doi: 10.1002/pbc.25555. Epub 2015 Apr 30.


Safety, tolerability, and immunogenicity of 15-valent pneumococcal conjugate vaccine in healthy adults.

McFetridge R, Meulen AS, Folkerth SD, Hoekstra JA, Dallas M, Hoover PA, Marchese RD, Zacholski DM, Watson WJ, Stek JE, Hartzel JS, Musey LK.

Vaccine. 2015 Jun 4;33(24):2793-9. doi: 10.1016/j.vaccine.2015.04.025. Epub 2015 Apr 23.


Safety, tolerability and immunogenicity of 15-valent pneumococcal conjugate vaccine in toddlers previously vaccinated with 7-valent pneumococcal conjugate vaccine.

Sobanjo-ter Meulen A, Vesikari T, Malacaman EA, Shapiro SA, Dallas MJ, Hoover PA, McFetridge R, Stek JE, Marchese RD, Hartzel J, Watson WJ, Musey LK.

Pediatr Infect Dis J. 2015 Feb;34(2):186-94. doi: 10.1097/INF.0000000000000516.


Rapid memory T-cell reconstitution recapitulating CD45RA-depleted haploidentical transplant graft content in patients with hematologic malignancies.

Triplett BM, Shook DR, Eldridge P, Li Y, Kang G, Dallas M, Hartford C, Srinivasan A, Chan WK, Suwannasaen D, Inaba H, Merchant TE, Pui CH, Leung W.

Bone Marrow Transplant. 2015 Jul;50(7):968-77. doi: 10.1038/bmt.2014.324. Epub 2015 Feb 9. Erratum in: Bone Marrow Transplant. 2015 Jul;50(7):1012.


Heme oxygenase-1 protects against Alzheimer's amyloid-β(1-42)-induced toxicity via carbon monoxide production.

Hettiarachchi N, Dallas M, Al-Owais M, Griffiths H, Hooper N, Scragg J, Boyle J, Peers C.

Cell Death Dis. 2014 Dec 11;5:e1569. doi: 10.1038/cddis.2014.529.


Osteoblast-specific deletion of Pkd2 leads to low-turnover osteopenia and reduced bone marrow adiposity.

Xiao Z, Cao L, Liang Y, Huang J, Stern AR, Dallas M, Johnson M, Quarles LD.

PLoS One. 2014 Dec 2;9(12):e114198. doi: 10.1371/journal.pone.0114198. eCollection 2014.


Enhanced cytotoxic function of natural killer and CD3+CD56+ cells in cord blood after culture.

Tomchuck SL, Leung WH, Dallas MH.

Biol Blood Marrow Transplant. 2015 Jan;21(1):39-49. doi: 10.1016/j.bbmt.2014.10.014. Epub 2014 Oct 18.


Gamma delta T cell reconstitution is associated with fewer infections and improved event-free survival after hematopoietic stem cell transplantation for pediatric leukemia.

Perko R, Kang G, Sunkara A, Leung W, Thomas PG, Dallas MH.

Biol Blood Marrow Transplant. 2015 Jan;21(1):130-6. doi: 10.1016/j.bbmt.2014.09.027. Epub 2014 Oct 16.


Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel.

Karttunen S, Duffield M, Scrimgeour NR, Squires L, Lim WL, Dallas ML, Scragg JL, Chicher J, Dave KA, Whitelaw ML, Peers C, Gorman JJ, Gleadle JM, Rychkov GY, Peet DJ.

J Cell Sci. 2015 Jan 15;128(2):225-31. doi: 10.1242/jcs.158451. Epub 2014 Nov 20.


Experimental and finite element analysis of dynamic loading of the mouse forearm.

Thiagarajan G, Lu Y, Dallas M, Johnson ML.

J Orthop Res. 2014 Dec;32(12):1580-8. doi: 10.1002/jor.22720. Epub 2014 Sep 5.


Hydrogen sulfide inhibits Cav3.2 T-type Ca2+ channels.

Elies J, Scragg JL, Huang S, Dallas ML, Huang D, MacDougall D, Boyle JP, Gamper N, Peers C.

FASEB J. 2014 Dec;28(12):5376-87. doi: 10.1096/fj.14-257113. Epub 2014 Sep 2.


Exogenous α-synuclein decreases raft partitioning of Cav2.2 channels inducing dopamine release.

Ronzitti G, Bucci G, Emanuele M, Leo D, Sotnikova TD, Mus LV, Soubrane CH, Dallas ML, Thalhammer A, Cingolani LA, Mochida S, Gainetdinov RR, Stephens GJ, Chieregatti E.

J Neurosci. 2014 Aug 6;34(32):10603-15. doi: 10.1523/JNEUROSCI.0608-14.2014.


SnRK1 phosphorylation of AL2 delays Cabbage leaf curl virus infection in Arabidopsis.

Shen W, Dallas MB, Goshe MB, Hanley-Bowdoin L.

J Virol. 2014 Sep;88(18):10598-612. doi: 10.1128/JVI.00761-14. Epub 2014 Jul 2.


Diverse mechanisms underlying the regulation of ion channels by carbon monoxide.

Peers C, Boyle JP, Scragg JL, Dallas ML, Al-Owais MM, Hettiarachichi NT, Elies J, Johnson E, Gamper N, Steele DS.

Br J Pharmacol. 2015 Mar;172(6):1546-56. doi: 10.1111/bph.12760. Epub 2014 Jul 2. Review.


Phase I study of the safety and pharmacokinetics of plerixafor in children undergoing a second allogeneic hematopoietic stem cell transplantation for relapsed or refractory leukemia.

Srinivasan A, Panetta JC, Cross SJ, Pillai A, Triplett BM, Shook DR, Dallas MH, Hartford C, Sunkara A, Kang G, Jacobsen J, Choi J, Leung W.

Biol Blood Marrow Transplant. 2014 Aug;20(8):1224-8. doi: 10.1016/j.bbmt.2014.04.020. Epub 2014 Apr 23.


Heme oxygenase-1 regulates cell proliferation via carbon monoxide-mediated inhibition of T-type Ca2+ channels.

Duckles H, Boycott HE, Al-Owais MM, Elies J, Johnson E, Dallas ML, Porter KE, Giuntini F, Boyle JP, Scragg JL, Peers C.

Pflugers Arch. 2015 Feb;467(2):415-27. doi: 10.1007/s00424-014-1503-5. Epub 2014 Apr 18.


Inhibition of the cardiac Na⁺ channel Nav1.5 by carbon monoxide.

Elies J, Dallas ML, Boyle JP, Scragg JL, Duke A, Steele DS, Peers C.

J Biol Chem. 2014 Jun 6;289(23):16421-9. doi: 10.1074/jbc.M114.569996. Epub 2014 Apr 9.


Can we improve cognitive-behavioral therapy for chronic back pain treatment engagement and adherence? A controlled trial of tailored versus standard therapy.

Kerns RD, Burns JW, Shulman M, Jensen MP, Nielson WR, Czlapinski R, Dallas MI, Chatkoff D, Sellinger J, Heapy A, Rosenberger P.

Health Psychol. 2014 Sep;33(9):938-47. doi: 10.1037/a0034406. Epub 2013 Dec 2.


Risk-adapted donor lymphocyte infusion based on chimerism and donor source in pediatric leukemia.

Rujkijyanont P, Morris C, Kang G, Gan K, Hartford C, Triplett B, Dallas M, Srinivasan A, Shook D, Pillai A, Pui CH, Leung W.

Blood Cancer J. 2013 Aug 30;3:e137. doi: 10.1038/bcj.2013.39.


Deletion of a single β-catenin allele in osteocytes abolishes the bone anabolic response to loading.

Javaheri B, Stern AR, Lara N, Dallas M, Zhao H, Liu Y, Bonewald LF, Johnson ML.

J Bone Miner Res. 2014 Mar;29(3):705-15. doi: 10.1002/jbmr.2064.


Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis.

Amako Y, Igloi Z, Mankouri J, Kazlauskas A, Saksela K, Dallas M, Peers C, Harris M.

J Biol Chem. 2013 Aug 23;288(34):24753-63. doi: 10.1074/jbc.M113.491985. Epub 2013 Jul 15.


Peptide aptamers that bind to geminivirus replication proteins confer a resistance phenotype to tomato yellow leaf curl virus and tomato mottle virus infection in tomato.

Reyes MI, Nash TE, Dallas MM, Ascencio-Ibáñez JT, Hanley-Bowdoin L.

J Virol. 2013 Sep;87(17):9691-706. doi: 10.1128/JVI.01095-13. Epub 2013 Jul 3.

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