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Items: 1 to 50 of 99

1.

Modeling Subcutaneous Absorption of Fast-Acting Insulin in Type 1 Diabetes.

Schiavon M, Dalla Man C, Cobelli C.

IEEE Trans Biomed Eng. 2017 Dec 15. doi: 10.1109/TBME.2017.2784101. [Epub ahead of print]

PMID:
29989928
2.

Differential effects of the circadian system and circadian misalignment on insulin sensitivity and insulin secretion in humans.

Qian J, Dalla Man C, Morris CJ, Cobelli C, Scheer FAJL.

Diabetes Obes Metab. 2018 Jun 4. doi: 10.1111/dom.13391. [Epub ahead of print]

PMID:
29862620
3.

Impaired insulin signaling in unaffected siblings and patients with first-episode psychosis.

Chouinard VA, Henderson DC, Dalla Man C, Valeri L, Gray BE, Ryan KP, Cypess AM, Cobelli C, Cohen BM, Öngür D.

Mol Psychiatry. 2018 Mar 9. doi: 10.1038/s41380-018-0045-1. [Epub ahead of print]

PMID:
29523870
4.

The UVA/Padova Type 1 Diabetes Simulator Goes From Single Meal to Single Day.

Visentin R, Campos-Náñez E, Schiavon M, Lv D, Vettoretti M, Breton M, Kovatchev BP, Dalla Man C, Cobelli C.

J Diabetes Sci Technol. 2018 Mar;12(2):273-281. doi: 10.1177/1932296818757747. Epub 2018 Feb 16.

PMID:
29451021
5.

Prospective evaluation of insulin and incretin dynamics in obese adults with and without diabetes for 2 years after Roux-en-Y gastric bypass.

Purnell JQ, Johnson GS, Wahed AS, Dalla Man C, Piccinini F, Cobelli C, Prigeon RL, Goodpaster BH, Kelley DE, Staten MA, Foster-Schubert KE, Cummings DE, Flum DR, Courcoulas AP, Havel PJ, Wolfe BM.

Diabetologia. 2018 May;61(5):1142-1154. doi: 10.1007/s00125-018-4553-y. Epub 2018 Feb 10.

PMID:
29428999
6.
7.

Twelve-Week 24/7 Ambulatory Artificial Pancreas With Weekly Adaptation of Insulin Delivery Settings: Effect on Hemoglobin A1c and Hypoglycemia.

Dassau E, Pinsker JE, Kudva YC, Brown SA, Gondhalekar R, Dalla Man C, Patek S, Schiavon M, Dadlani V, Dasanayake I, Church MM, Carter RE, Bevier WC, Huyett LM, Hughes J, Anderson S, Lv D, Schertz E, Emory E, McCrady-Spitzer SK, Jean T, Bradley PK, Hinshaw L, Laguna Sanz AJ, Basu A, Kovatchev B, Cobelli C, Doyle FJ 3rd.

Diabetes Care. 2017 Dec;40(12):1719-1726. doi: 10.2337/dc17-1188. Epub 2017 Oct 13.

PMID:
29030383
8.

Performance of individually measured vs population-based C-peptide kinetics to assess β-cell function in the presence and absence of acute insulin resistance.

Varghese RT, Dalla Man C, Laurenti MC, Piccinini F, Sharma A, Shah M, Bailey KR, Rizza RA, Cobelli C, Vella A.

Diabetes Obes Metab. 2018 Mar;20(3):549-555. doi: 10.1111/dom.13106. Epub 2017 Sep 27.

PMID:
28862812
9.

The rs7903146 Variant in the TCF7L2 Gene Increases the Risk of Prediabetes/Type 2 Diabetes in Obese Adolescents by Impairing β-Cell Function and Hepatic Insulin Sensitivity.

Cropano C, Santoro N, Groop L, Dalla Man C, Cobelli C, Galderisi A, Kursawe R, Pierpont B, Goffredo M, Caprio S.

Diabetes Care. 2017 Aug;40(8):1082-1089. doi: 10.2337/dc17-0290. Epub 2017 Jun 13.

PMID:
28611053
10.

Glucose metabolism during rotational shift-work in healthcare workers.

Sharma A, Laurenti MC, Dalla Man C, Varghese RT, Cobelli C, Rizza RA, Matveyenko A, Vella A.

Diabetologia. 2017 Aug;60(8):1483-1490. doi: 10.1007/s00125-017-4317-0. Epub 2017 May 27.

PMID:
28551698
11.

Liver triacylglycerol content and gestational diabetes: effects of moderate energy restriction.

Hodson K, Dalla Man C, Smith FE, Barnes A, McParlin C, Cobelli C, Robson SC, Araújo-Soares V, Taylor R.

Diabetologia. 2017 Feb;60(2):306-313. doi: 10.1007/s00125-016-4143-9. Epub 2016 Nov 5.

PMID:
27817155
12.

Long-Term Outcomes of Biliopancreatic Diversion on Glycemic Control, Insulin Sensitivity and Beta Cell Function.

Vasques AC, Pareja JC, da Saúde de Oliveira M, Novaes FS, Lima MM, Chaim ÉA, Piccinini F, Dalla Man C, Cobelli C, Geloneze B.

Obes Surg. 2016 Nov;26(11):2572-2580.

PMID:
27091049
13.

Mechanisms Underlying the Pathogenesis of Isolated Impaired Glucose Tolerance in Humans.

Varghese RT, Dalla Man C, Sharma A, Viegas I, Barosa C, Marques C, Shah M, Miles JM, Rizza RA, Jones JG, Cobelli C, Vella A.

J Clin Endocrinol Metab. 2016 Dec;101(12):4816-4824. Epub 2016 Sep 7.

14.

Standardized Mixed-Meal Tolerance and Arginine Stimulation Tests Provide Reproducible and Complementary Measures of β-Cell Function: Results From the Foundation for the National Institutes of Health Biomarkers Consortium Investigative Series.

Shankar SS, Vella A, Raymond RH, Staten MA, Calle RA, Bergman RN, Cao C, Chen D, Cobelli C, Dalla Man C, Deeg M, Dong JQ, Lee DS, Polidori D, Robertson RP, Ruetten H, Stefanovski D, Vassileva MT, Weir GC, Fryburg DA; Foundation for the National Institutes of Health β-Cell Project Team.

Diabetes Care. 2016 Sep;39(9):1602-13. doi: 10.2337/dc15-0931. Epub 2016 Jul 12.

15.

Improving Efficacy of Inhaled Technosphere Insulin (Afrezza) by Postmeal Dosing: In-silico Clinical Trial with the University of Virginia/Padova Type 1 Diabetes Simulator.

Visentin R, Giegerich C, Jäger R, Dahmen R, Boss A, Grant M, Dalla Man C, Cobelli C, Klabunde T.

Diabetes Technol Ther. 2016 Sep;18(9):574-85. doi: 10.1089/dia.2016.0128. Epub 2016 Jun 22.

16.

Interstitial Fluid Glucose Is Not Just a Shifted-in-Time but a Distorted Mirror of Blood Glucose: Insight from an In Silico Study.

Cobelli C, Schiavon M, Dalla Man C, Basu A, Basu R.

Diabetes Technol Ther. 2016 Aug;18(8):505-11. doi: 10.1089/dia.2016.0112. Epub 2016 Jun 2.

17.

Effects of the BET-inhibitor, RVX-208 on the HDL lipidome and glucose metabolism in individuals with prediabetes: A randomized controlled trial.

Siebel AL, Trinh SK, Formosa MF, Mundra PA, Natoli AK, Reddy-Luthmoodoo M, Huynh K, Khan AA, Carey AL, van Hall G, Cobelli C, Dalla-Man C, Otvos JD, Rye KA, Johansson J, Gordon A, Wong NC, Sviridov D, Barter P, Duffy SJ, Meikle PJ, Kingwell BA.

Metabolism. 2016 Jun;65(6):904-14. doi: 10.1016/j.metabol.2016.03.002. Epub 2016 Mar 8.

PMID:
27173469
18.

Effect of Pramlintide on Postprandial Glucose Fluxes in Type 1 Diabetes.

Hinshaw L, Schiavon M, Dadlani V, Mallad A, Dalla Man C, Bharucha A, Basu R, Geske JR, Carter RE, Cobelli C, Basu A, Kudva YC.

J Clin Endocrinol Metab. 2016 May;101(5):1954-62. doi: 10.1210/jc.2015-3952. Epub 2016 Mar 1.

19.

Model-Based Quantification of Glucagon-Like Peptide-1-Induced Potentiation of Insulin Secretion in Response to a Mixed Meal Challenge.

Dalla Man C, Micheletto F, Sathananthan M, Vella A, Cobelli C.

Diabetes Technol Ther. 2016 Jan;18(1):39-46. doi: 10.1089/dia.2015.0146.

20.

Incorporation of inhaled insulin into the FDA accepted University of Virginia/Padova Type 1 Diabetes Simulator.

Visentin R, Klabunde T, Grant M, Dalla Man C, Cobelli C.

Conf Proc IEEE Eng Med Biol Soc. 2015;2015:3250-3. doi: 10.1109/EMBC.2015.7319085.

PMID:
26736985
21.

A Model for the Estimation of Hepatic Insulin Extraction After a Meal.

Piccinini F, Dalla Man C, Vella A, Cobelli C.

IEEE Trans Biomed Eng. 2016 Sep;63(9):1925-1932. doi: 10.1109/TBME.2015.2505507. Epub 2015 Dec 4.

22.

TCF7L2 Genotype and α-Cell Function in Humans Without Diabetes.

Shah M, Varghese RT, Miles JM, Piccinini F, Dalla Man C, Cobelli C, Bailey KR, Rizza RA, Vella A.

Diabetes. 2016 Feb;65(2):371-80. doi: 10.2337/db15-1233. Epub 2015 Nov 2.

23.

Modeling Plasma-to-Interstitium Glucose Kinetics from Multitracer Plasma and Microdialysis Data.

Schiavon M, Dalla Man C, Dube S, Slama M, Kudva YC, Peyser T, Basu A, Basu R, Cobelli C.

Diabetes Technol Ther. 2015 Nov;17(11):825-31. doi: 10.1089/dia.2015.0119. Epub 2015 Aug 27.

24.

Adjustment of Open-Loop Settings to Improve Closed-Loop Results in Type 1 Diabetes: A Multicenter Randomized Trial.

Dassau E, Brown SA, Basu A, Pinsker JE, Kudva YC, Gondhalekar R, Patek S, Lv D, Schiavon M, Lee JB, Dalla Man C, Hinshaw L, Castorino K, Mallad A, Dadlani V, McCrady-Spitzer SK, McElwee-Malloy M, Wakeman CA, Bevier WC, Bradley PK, Kovatchev B, Cobelli C, Zisser HC, Doyle FJ 3rd.

J Clin Endocrinol Metab. 2015 Oct;100(10):3878-86. doi: 10.1210/jc.2015-2081. Epub 2015 Jul 23.

25.

Glucagon sensitivity and clearance in type 1 diabetes: insights from in vivo and in silico experiments.

Hinshaw L, Mallad A, Dalla Man C, Basu R, Cobelli C, Carter RE, Kudva YC, Basu A.

Am J Physiol Endocrinol Metab. 2015 Sep 1;309(5):E474-86. doi: 10.1152/ajpendo.00236.2015. Epub 2015 Jul 7.

26.

Nocturnal Glucose Metabolism in Type 1 Diabetes: A Study Comparing Single Versus Dual Tracer Approaches.

Mallad A, Hinshaw L, Dalla Man C, Cobelli C, Basu R, Lingineni R, Carter RE, Kudva YC, Basu A.

Diabetes Technol Ther. 2015 Aug;17(8):587-95. doi: 10.1089/dia.2015.0011. Epub 2015 Jun 29.

27.

Hepatic insulin sensitivity in healthy and prediabetic subjects: from a dual- to a single-tracer oral minimal model.

Visentin R, Dalla Man C, Basu R, Basu A, Rizza RA, Cobelli C.

Am J Physiol Endocrinol Metab. 2015 Jul 15;309(2):E161-7. doi: 10.1152/ajpendo.00358.2014. Epub 2015 May 19.

28.

A common variant in the MTNR1b gene is associated with increased risk of impaired fasting glucose (IFG) in youth with obesity.

Zheng C, Dalla Man C, Cobelli C, Groop L, Zhao H, Bale AE, Shaw M, Duran E, Pierpont B, Caprio S, Santoro N.

Obesity (Silver Spring). 2015 May;23(5):1022-9. doi: 10.1002/oby.21030.

29.

Exercise effects on postprandial glucose metabolism in type 1 diabetes: a triple-tracer approach.

Mallad A, Hinshaw L, Schiavon M, Dalla Man C, Dadlani V, Basu R, Lingineni R, Cobelli C, Johnson ML, Carter R, Kudva YC, Basu A.

Am J Physiol Endocrinol Metab. 2015 Jun 15;308(12):E1106-15. doi: 10.1152/ajpendo.00014.2015. Epub 2015 Apr 21.

30.

An index of parameter reproducibility accounting for estimation uncertainty: theory and case study on β-cell responsivity and insulin sensitivity.

Dalla Man C, Pillonetto G, Riz M, Cobelli C.

Am J Physiol Endocrinol Metab. 2015 Jun 1;308(11):E971-7. doi: 10.1152/ajpendo.00350.2014. Epub 2015 Apr 7.

31.

Association between thyrotropin levels and insulin sensitivity in euthyroid obese adolescents.

Javed A, Balagopal PB, Vella A, Fischer PR, Piccinini F, Dalla Man C, Cobelli C, Giesler PD, Laugen JM, Kumar S.

Thyroid. 2015 May;25(5):478-84. doi: 10.1089/thy.2015.0005. Epub 2015 Apr 7.

32.

Cholecalciferol supplementation does not influence β-cell function and insulin action in obese adolescents: a prospective double-blind randomized trial.

Javed A, Vella A, Balagopal PB, Fischer PR, Weaver AL, Piccinini F, Dalla Man C, Cobelli C, Giesler PD, Laugen JM, Kumar S.

J Nutr. 2015 Feb;145(2):284-90. doi: 10.3945/jn.114.202010. Epub 2014 Dec 17.

PMID:
25644349
33.

Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training.

Konopka AR, Asante A, Lanza IR, Robinson MM, Johnson ML, Dalla Man C, Cobelli C, Amols MH, Irving BA, Nair KS.

Diabetes. 2015 Jun;64(6):2104-15. doi: 10.2337/db14-1701. Epub 2015 Jan 20.

34.

Circadian variability of insulin sensitivity: physiological input for in silico artificial pancreas.

Visentin R, Dalla Man C, Kudva YC, Basu A, Cobelli C.

Diabetes Technol Ther. 2015 Jan;17(1):1-7. doi: 10.1089/dia.2014.0192.

35.

Epicardial and pericardial fat in type 2 diabetes: favourable effects of biliopancreatic diversion.

Vasques AC, Pareja JC, Souza JR, Yamanaka A, de Oliveira Mda S, Novaes FS, Chaim ÉA, Piccinini F, Dalla Man C, Cobelli C, Geloneze B.

Obes Surg. 2015 Mar;25(3):477-85. doi: 10.1007/s11695-014-1400-1.

PMID:
25148887
36.

Ethnic differences in insulin sensitivity, β-cell function, and hepatic extraction between Japanese and Caucasians: a minimal model analysis.

Møller JB, Dalla Man C, Overgaard RV, Ingwersen SH, Tornøe CW, Pedersen M, Tanaka H, Ohsugi M, Ueki K, Lynge J, Vasconcelos NM, Pedersen BK, Kadowaki T, Cobelli C.

J Clin Endocrinol Metab. 2014 Nov;99(11):4273-80. doi: 10.1210/jc.2014-1724. Epub 2014 Aug 13.

PMID:
25119313
37.

The effect of vagal nerve blockade using electrical impulses on glucose metabolism in nondiabetic subjects.

Sathananthan M, Ikramuddin S, Swain JM, Shah M, Piccinini F, Dalla Man C, Cobelli C, Rizza RA, Camilleri M, Vella A.

Diabetes Metab Syndr Obes. 2014 Jul 11;7:305-12. doi: 10.2147/DMSO.S65733. eCollection 2014.

38.

Multicenter closed-loop insulin delivery study points to challenges for keeping blood glucose in a safe range by a control algorithm in adults and adolescents with type 1 diabetes from various sites.

Zisser H, Renard E, Kovatchev B, Cobelli C, Avogaro A, Nimri R, Magni L, Buckingham BA, Chase HP, Doyle FJ 3rd, Lum J, Calhoun P, Kollman C, Dassau E, Farret A, Place J, Breton M, Anderson SM, Dalla Man C, Del Favero S, Bruttomesso D, Filippi A, Scotton R, Phillip M, Atlas E, Muller I, Miller S, Toffanin C, Raimondo DM, De Nicolao G, Beck RW; Control to Range Study Group.

Diabetes Technol Ther. 2014 Oct;16(10):613-22. doi: 10.1089/dia.2014.0066. Epub 2014 Jul 8. Erratum in: Diabetes Technol Ther. 2015 Jan;17(1):68. Vistenin, Roberto [corrected to Visentin, Roberto].

39.

The oral minimal model method.

Cobelli C, Dalla Man C, Toffolo G, Basu R, Vella A, Rizza R.

Diabetes. 2014 Apr;63(4):1203-13. doi: 10.2337/db13-1198. Review.

40.

The university of Virginia/Padova type 1 diabetes simulator matches the glucose traces of a clinical trial.

Visentin R, Dalla Man C, Kovatchev B, Cobelli C.

Diabetes Technol Ther. 2014 Jul;16(7):428-34. doi: 10.1089/dia.2013.0377. Epub 2014 Feb 26.

41.

In silico optimization of basal insulin infusion rate during exercise: implication for artificial pancreas.

Schiavon M, Dalla Man C, Kudva YC, Basu A, Cobelli C.

J Diabetes Sci Technol. 2013 Nov 1;7(6):1461-9.

42.

Quantitative estimation of insulin sensitivity in type 1 diabetic subjects wearing a sensor-augmented insulin pump.

Schiavon M, Dalla Man C, Kudva YC, Basu A, Cobelli C.

Diabetes Care. 2014;37(5):1216-23. doi: 10.2337/dc13-1120. Epub 2013 Dec 6.

43.

Day and night closed-loop control in adults with type 1 diabetes: a comparison of two closed-loop algorithms driving continuous subcutaneous insulin infusion versus patient self-management.

Luijf YM, DeVries JH, Zwinderman K, Leelarathna L, Nodale M, Caldwell K, Kumareswaran K, Elleri D, Allen JM, Wilinska ME, Evans ML, Hovorka R, Doll W, Ellmerer M, Mader JK, Renard E, Place J, Farret A, Cobelli C, Del Favero S, Dalla Man C, Avogaro A, Bruttomesso D, Filippi A, Scotton R, Magni L, Lanzola G, Di Palma F, Soru P, Toffanin C, De Nicolao G, Arnolds S, Benesch C, Heinemann L; AP@home Consortium.

Diabetes Care. 2013 Dec;36(12):3882-7. doi: 10.2337/dc12-1956. Epub 2013 Oct 29.

44.

β-Cell function improvements in grade I/II obese subjects with type 2 diabetes 1 month after biliopancreatic diversion: results from modeling analyses of oral glucose tolerance tests and hyperglycemic clamp studies.

Junqueira Vasques AC, Pareja JC, de Oliveira Mda S, Satake Novaes F, Miranda de Oliveira Lima M, Chaim ÉA, Piccinini F, Dalla Man C, Cobelli C, Geloneze B.

Diabetes Care. 2013 Dec;36(12):4117-24. doi: 10.2337/dc13-0530. Epub 2013 Oct 17.

45.

Contribution of endogenous glucagon-like peptide 1 to glucose metabolism after Roux-en-Y gastric bypass.

Shah M, Law JH, Micheletto F, Sathananthan M, Dalla Man C, Cobelli C, Rizza RA, Camilleri M, Zinsmeister AR, Vella A.

Diabetes. 2014 Feb;63(2):483-93. doi: 10.2337/db13-0954. Epub 2013 Oct 2.

46.

Co-occurrence of risk alleles in or near genes modulating insulin secretion predisposes obese youth to prediabetes.

Giannini C, Dalla Man C, Groop L, Cobelli C, Zhao H, Shaw MM, Duran E, Pierpont B, Bale AE, Caprio S, Santoro N.

Diabetes Care. 2014 Feb;37(2):475-82. doi: 10.2337/dc13-1458. Epub 2013 Sep 23.

47.

Physical activity measured by physical activity monitoring system correlates with glucose trends reconstructed from continuous glucose monitoring.

Zecchin C, Facchinetti A, Sparacino G, Dalla Man C, Manohar C, Levine JA, Basu A, Kudva YC, Cobelli C.

Diabetes Technol Ther. 2013 Oct;15(10):836-44. doi: 10.1089/dia.2013.0105. Epub 2013 Aug 14.

48.

In silico design of optimal ratio for co-administration of pramlintide and insulin in type 1 diabetes.

Micheletto F, Dalla Man C, Kolterman O, Chiquette E, Herrmann K, Schirra J, Kovatchev B, Cobelli C.

Diabetes Technol Ther. 2013 Oct;15(10):802-9. doi: 10.1089/dia.2013.0054. Epub 2013 Jul 18.

49.

Postprandial glucose fluxes and insulin sensitivity during exercise: a study in healthy individuals.

Schiavon M, Hinshaw L, Mallad A, Dalla Man C, Sparacino G, Johnson M, Carter R, Basu R, Kudva Y, Cobelli C, Basu A.

Am J Physiol Endocrinol Metab. 2013 Aug 15;305(4):E557-66. doi: 10.1152/ajpendo.00182.2013. Epub 2013 Jul 2.

50.

Direct effects of exendin-(9,39) and GLP-1-(9,36)amide on insulin action, β-cell function, and glucose metabolism in nondiabetic subjects.

Sathananthan M, Farrugia LP, Miles JM, Piccinini F, Dalla Man C, Zinsmeister AR, Cobelli C, Rizza RA, Vella A.

Diabetes. 2013 Aug;62(8):2752-6. doi: 10.2337/db13-0140. Epub 2013 Apr 1.

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