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Items: 1 to 50 of 354

1.

Author Correction: A systems biology pipeline identifies regulatory networks for stem cell engineering.

Kinney MA, Vo LT, Frame JM, Barragan J, Conway AJ, Li S, Wong KK, Collins JJ, Cahan P, North TE, Lauffenburger DA, Daley GQ.

Nat Biotechnol. 2019 Aug;37(8):962. doi: 10.1038/s41587-019-0212-1.

PMID:
31312048
2.

A systems biology pipeline identifies regulatory networks for stem cell engineering.

Kinney MA, Vo LT, Frame JM, Barragan J, Conway AJ, Li S, Wong KK, Collins JJ, Cahan P, North TE, Lauffenburger DA, Daley GQ.

Nat Biotechnol. 2019 Jul;37(7):810-818. doi: 10.1038/s41587-019-0159-2. Epub 2019 Jul 1. Erratum in: Nat Biotechnol. 2019 Aug;37(8):962.

PMID:
31267104
3.

Stem Cells in the Treatment of Disease.

Blau HM, Daley GQ.

N Engl J Med. 2019 May 2;380(18):1748-1760. doi: 10.1056/NEJMra1716145. Review. No abstract available.

PMID:
31042827
4.

Induced pluripotent stem cells in disease modelling and drug discovery.

Rowe RG, Daley GQ.

Nat Rev Genet. 2019 Jul;20(7):377-388. doi: 10.1038/s41576-019-0100-z. Review.

PMID:
30737492
5.

The developmental stage of the hematopoietic niche regulates lineage in MLL-rearranged leukemia.

Rowe RG, Lummertz da Rocha E, Sousa P, Missios P, Morse M, Marion W, Yermalovich A, Barragan J, Mathieu R, Jha DK, Fleming MD, North TE, Daley GQ.

J Exp Med. 2019 Mar 4;216(3):527-538. doi: 10.1084/jem.20181765. Epub 2019 Feb 6.

PMID:
30728174
6.

The Lin28/let-7 Pathway Regulates the Mammalian Caudal Body Axis Elongation Program.

Robinton DA, Chal J, Lummertz da Rocha E, Han A, Yermalovich AV, Oginuma M, Schlaeger TM, Sousa P, Rodriguez A, Urbach A, Pourquié O, Daley GQ.

Dev Cell. 2019 Feb 11;48(3):396-405.e3. doi: 10.1016/j.devcel.2018.12.016. Epub 2019 Jan 17.

PMID:
30661985
7.

After the Storm - A Responsible Path for Genome Editing.

Daley GQ, Lovell-Badge R, Steffann J.

N Engl J Med. 2019 Mar 7;380(10):897-899. doi: 10.1056/NEJMp1900504. Epub 2019 Jan 16. No abstract available.

PMID:
30649993
8.

Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis.

Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ.

Nat Commun. 2019 Jan 11;10(1):168. doi: 10.1038/s41467-018-08127-4.

9.

Lin28b regulates age-dependent differences in murine platelet function.

Stolla MC, Catherman SC, Kingsley PD, Rowe RG, Koniski AD, Fegan K, Vit L, McGrath KE, Daley GQ, Palis J.

Blood Adv. 2019 Jan 8;3(1):72-82. doi: 10.1182/bloodadvances.2018020859.

10.

Retraction Note: NF-κB activation impairs somatic cell reprogramming in ageing.

Soria-Valles C, Osorio FG, Gutiérrez-Fernández A, De Los Angeles A, Bueno C, Menéndez P, Martín-Subero JI, Daley GQ, Freije JMP, López-Otín C.

Nat Cell Biol. 2019 Mar;21(3):410. doi: 10.1038/s41556-018-0259-0.

PMID:
30559458
11.

Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28.

Wang L, Rowe RG, Jaimes A, Yu C, Nam Y, Pearson DS, Zhang J, Xie X, Marion W, Heffron GJ, Daley GQ, Sliz P.

Cell Rep. 2018 Jun 5;23(10):3091-3101. doi: 10.1016/j.celrep.2018.04.116.

12.

A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development.

Cesana M, Guo MH, Cacchiarelli D, Wahlster L, Barragan J, Doulatov S, Vo LT, Salvatori B, Trapnell C, Clement K, Cahan P, Tsanov KM, Sousa PM, Tazon-Vega B, Bolondi A, Giorgi FM, Califano A, Rinn JL, Meissner A, Hirschhorn JN, Daley GQ.

Cell Stem Cell. 2018 Apr 5;22(4):575-588.e7. doi: 10.1016/j.stem.2018.03.012.

13.

Reconstruction of complex single-cell trajectories using CellRouter.

Lummertz da Rocha E, Rowe RG, Lundin V, Malleshaiah M, Jha DK, Rambo CR, Li H, North TE, Collins JJ, Daley GQ.

Nat Commun. 2018 Mar 1;9(1):892. doi: 10.1038/s41467-018-03214-y.

14.

Regulation of embryonic haematopoietic multipotency by EZH1.

Vo LT, Kinney MA, Liu X, Zhang Y, Barragan J, Sousa PM, Jha DK, Han A, Cesana M, Shao Z, North TE, Orkin SH, Doulatov S, Xu J, Daley GQ.

Nature. 2018 Jan 25;553(7689):506-510. doi: 10.1038/nature25435. Epub 2018 Jan 17.

15.

Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling.

Chandrasekaran S, Zhang J, Sun Z, Zhang L, Ross CA, Huang YC, Asara JM, Li H, Daley GQ, Collins JJ.

Cell Rep. 2017 Dec 5;21(10):2965-2977. doi: 10.1016/j.celrep.2017.07.048.

16.

Is There Merit in Merit Aid?

Ziegelstein RC, Prober CG, Minor LB, Daley GQ, Rothman PB, Hundert EM.

N Engl J Med. 2017 Dec 21;377(25):2415-2417. doi: 10.1056/NEJMp1713146. Epub 2017 Oct 25. No abstract available.

PMID:
29069550
17.

Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration.

Burnight ER, Gupta M, Wiley LA, Anfinson KR, Tran A, Triboulet R, Hoffmann JM, Klaahsen DL, Andorf JL, Jiao C, Sohn EH, Adur MK, Ross JW, Mullins RF, Daley GQ, Schlaeger TM, Stone EM, Tucker BA.

Mol Ther. 2017 Sep 6;25(9):1999-2013. doi: 10.1016/j.ymthe.2017.05.015. Epub 2017 Jun 12.

18.

Haematopoietic stem and progenitor cells from human pluripotent stem cells.

Sugimura R, Jha DK, Han A, Soria-Valles C, da Rocha EL, Lu YF, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, Keller G, Engelman AN, Snapper SB, Doulatov S, Daley GQ.

Nature. 2017 May 25;545(7655):432-438. doi: 10.1038/nature22370. Epub 2017 May 17.

19.

Reassembling embryos in vitro from component stem cells.

Kubaczka C, Daley GQ.

Cell Res. 2017 Aug;27(8):961-962. doi: 10.1038/cr.2017.61. Epub 2017 Apr 21. Review.

20.

Autophagy: It's in Your Blood.

Doulatov S, Daley GQ.

Dev Cell. 2017 Mar 27;40(6):518-520. doi: 10.1016/j.devcel.2017.03.011.

21.

Polar Extremes in the Clinical Use of Stem Cells.

Daley GQ.

N Engl J Med. 2017 Mar 16;376(11):1075-1077. doi: 10.1056/NEJMe1701379. No abstract available.

PMID:
28296612
22.

Signaling through RNA-binding proteins as a cell fate regulatory mechanism.

Tsanov KM, Daley GQ.

Cell Cycle. 2017 Apr 18;16(8):723-724. doi: 10.1080/15384101.2017.1302205. Epub 2017 Mar 8. No abstract available.

23.

Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors.

Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ.

Sci Transl Med. 2017 Feb 8;9(376). pii: eaah5645. doi: 10.1126/scitranslmed.aah5645.

24.

Disruptive reproductive technologies.

Cohen IG, Daley GQ, Adashi EY.

Sci Transl Med. 2017 Jan 11;9(372). pii: eaag2959. doi: 10.1126/scitranslmed.aag2959.

PMID:
28077678
25.

Engineered Murine HSCs Reconstitute Multi-lineage Hematopoiesis and Adaptive Immunity.

Lu YF, Cahan P, Ross S, Sahalie J, Sousa PM, Hadland BK, Cai W, Serrao E, Engelman AN, Bernstein ID, Daley GQ.

Cell Rep. 2016 Dec 20;17(12):3178-3192. doi: 10.1016/j.celrep.2016.11.077.

26.

LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency.

Tsanov KM, Pearson DS, Wu Z, Han A, Triboulet R, Seligson MT, Powers JT, Osborne JK, Kane S, Gygi SP, Gregory RI, Daley GQ.

Nat Cell Biol. 2017 Jan;19(1):60-67. doi: 10.1038/ncb3453. Epub 2016 Dec 19.

27.

Stem cells: Valine starvation leads to a hungry niche.

Rowe RG, Daley GQ.

Nature. 2017 Jan 12;541(7636):166-167. doi: 10.1038/nature21106. Epub 2016 Dec 14. No abstract available.

28.

Progress towards generation of human haematopoietic stem cells.

Wahlster L, Daley GQ.

Nat Cell Biol. 2016 Nov;18(11):1111-1117. doi: 10.1038/ncb3419. Epub 2016 Oct 10. Review.

PMID:
27723718
29.

TGF-β inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors.

Gao X, Lee HY, da Rocha EL, Zhang C, Lu YF, Li D, Feng Y, Ezike J, Elmes RR, Barrasa MI, Cahan P, Li H, Daley GQ, Lodish HF.

Blood. 2016 Dec 8;128(23):2637-2641. Epub 2016 Oct 24.

30.

The LIN28B/let-7 axis is a novel therapeutic pathway in multiple myeloma.

Manier S, Powers JT, Sacco A, Glavey SV, Huynh D, Reagan MR, Salem KZ, Moschetta M, Shi J, Mishima Y, Roche-Lestienne C, Leleu X, Roccaro AM, Daley GQ, Ghobrial IM.

Leukemia. 2017 Apr;31(4):853-860. doi: 10.1038/leu.2016.296. Epub 2016 Oct 24.

31.

Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production.

Cortes M, Chen MJ, Stachura DL, Liu SY, Kwan W, Wright F, Vo LT, Theodore LN, Esain V, Frost IM, Schlaeger TM, Goessling W, Daley GQ, North TE.

Cell Rep. 2016 Oct 4;17(2):458-468. doi: 10.1016/j.celrep.2016.09.012.

32.

Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis.

Rowe RG, Wang LD, Coma S, Han A, Mathieu R, Pearson DS, Ross S, Sousa P, Nguyen PT, Rodriguez A, Wagers AJ, Daley GQ.

J Exp Med. 2016 Jul 25;213(8):1497-512. doi: 10.1084/jem.20151912. Epub 2016 Jul 11.

33.

Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma.

Powers JT, Tsanov KM, Pearson DS, Roels F, Spina CS, Ebright R, Seligson M, de Soysa Y, Cahan P, Theißen J, Tu HC, Han A, Kurek KC, LaPier GS, Osborne JK, Ross SJ, Cesana M, Collins JJ, Berthold F, Daley GQ.

Nature. 2016 Jul 14;535(7611):246-51. doi: 10.1038/nature18632. Epub 2016 Jul 6.

34.

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency.

Zhang J, Ratanasirintrawoot S, Chandrasekaran S, Wu Z, Ficarro SB, Yu C, Ross CA, Cacchiarelli D, Xia Q, Seligson M, Shinoda G, Xie W, Cahan P, Wang L, Ng SC, Tintara S, Trapnell C, Onder T, Loh YH, Mikkelsen T, Sliz P, Teitell MA, Asara JM, Marto JA, Li H, Collins JJ, Daley GQ.

Cell Stem Cell. 2016 Jul 7;19(1):66-80. doi: 10.1016/j.stem.2016.05.009. Epub 2016 Jun 16.

35.

RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming.

Toh CX, Chan JW, Chong ZS, Wang HF, Guo HC, Satapathy S, Ma D, Goh GY, Khattar E, Yang L, Tergaonkar V, Chang YT, Collins JJ, Daley GQ, Wee KB, Farran CA, Li H, Lim YP, Bard FA, Loh YH.

Cell Rep. 2016 Jun 21;15(12):2597-607. doi: 10.1016/j.celrep.2016.05.049. Epub 2016 Jun 9.

36.

Engineering Hematopoietic Stem Cells: Lessons from Development.

Rowe RG, Mandelbaum J, Zon LI, Daley GQ.

Cell Stem Cell. 2016 Jun 2;18(6):707-20. doi: 10.1016/j.stem.2016.05.016. Review.

37.

Policy: Global standards for stem-cell research.

Kimmelman J, Hyun I, Benvenisty N, Caulfield T, Heslop HE, Murry CE, Sipp D, Studer L, Sugarman J, Daley GQ.

Nature. 2016 May 19;533(7603):311-3. doi: 10.1038/533311a. No abstract available.

PMID:
27193661
38.

Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines.

Daley GQ, Hyun I, Apperley JF, Barker RA, Benvenisty N, Bredenoord AL, Breuer CK, Caulfield T, Cedars MI, Frey-Vasconcells J, Heslop HE, Jin Y, Lee RT, McCabe C, Munsie M, Murry CE, Piantadosi S, Rao M, Rooke HM, Sipp D, Studer L, Sugarman J, Takahashi M, Zimmerman M, Kimmelman J.

Stem Cell Reports. 2016 Jun 14;6(6):787-797. doi: 10.1016/j.stemcr.2016.05.001. Epub 2016 May 12.

39.

New ISSCR guidelines: clinical translation of stem cell research.

Kimmelman J, Heslop HE, Sugarman J, Studer L, Benvenisty N, Caulfield T, Hyun I, Murry CE, Sipp D, Daley GQ.

Lancet. 2016 May 14;387(10032):1979-81. No abstract available.

PMID:
27179752
40.

SCIENTIFIC COMMUNITY. Confronting stem cell hype.

Caulfield T, Sipp D, Murry CE, Daley GQ, Kimmelman J.

Science. 2016 May 13;352(6287):776-7. doi: 10.1126/science.aaf4620. Epub 2016 May 12. No abstract available.

PMID:
27174977
41.

Chronic myeloid leukemia: reminiscences and dreams.

Mughal TI, Radich JP, Deininger MW, Apperley JF, Hughes TP, Harrison CJ, Gambacorti-Passerini C, Saglio G, Cortes J, Daley GQ.

Haematologica. 2016 May;101(5):541-58. doi: 10.3324/haematol.2015.139337. Review.

42.

Interferon-α signaling promotes embryonic HSC maturation.

Kim PG, Canver MC, Rhee C, Ross SJ, Harriss JV, Tu HC, Orkin SH, Tucker HO, Daley GQ.

Blood. 2016 Jul 14;128(2):204-16. doi: 10.1182/blood-2016-01-689281. Epub 2016 Apr 19.

43.

Sex-specific regulation of weight and puberty by the Lin28/let-7 axis.

Corre C, Shinoda G, Zhu H, Cousminer DL, Crossman C, Bellissimo C, Goldenberg A, Daley GQ, Palmert MR.

J Endocrinol. 2016 Mar;228(3):179-91. doi: 10.1530/JOE-15-0360. Epub 2015 Dec 23.

44.

Corrigendum: Hallmarks of pluripotency.

De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, Park PJ, Daley GQ.

Nature. 2016 Mar 17;531(7594):400. doi: 10.1038/nature16470. Epub 2015 Dec 16. No abstract available.

PMID:
26675727
45.

Corrigendum: Failure to replicate the STAP cell phenomenon.

De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, Borkent M, Krupalnik V, Lujan E, Wernig M, Hanna JH, Hochedlinger K, Pei D, Jaenisch R, Deng H, Orkin SH, Park PJ, Daley GQ.

Nature. 2016 Mar 17;531(7594):400. doi: 10.1038/nature16479. Epub 2015 Dec 16. No abstract available.

PMID:
26675720
46.

Precise let-7 expression levels balance organ regeneration against tumor suppression.

Wu L, Nguyen LH, Zhou K, de Soysa TY, Li L, Miller JB, Tian J, Locker J, Zhang S, Shinoda G, Seligson MT, Zeitels LR, Acharya A, Wang SC, Mendell JT, He X, Nishino J, Morrison SJ, Siegwart DJ, Daley GQ, Shyh-Chang N, Zhu H.

Elife. 2015 Oct 7;4:e09431. doi: 10.7554/eLife.09431.

47.

Stem cells and the evolving notion of cellular identity.

Daley GQ.

Philos Trans R Soc Lond B Biol Sci. 2015 Oct 19;370(1680):20140376. doi: 10.1098/rstb.2014.0376. Review.

48.

Failure to replicate the STAP cell phenomenon.

De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, Borkent M, Krupalnik V, Lujan E, Wernig M, Hanna JH, Hochedlinger K, Pei D, Jaenisch R, Deng H, Orkin SH, Park PJ, Daley GQ.

Nature. 2015 Sep 24;525(7570):E6-9. doi: 10.1038/nature15513. No abstract available. Erratum in: Nature. 2016 Mar 17;531(7594):400.

PMID:
26399835
49.

Hallmarks of pluripotency.

De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, Park PJ, Daley GQ.

Nature. 2015 Sep 24;525(7570):469-78. doi: 10.1038/nature15515. Review. Erratum in: Nature. 2016 Mar 17;531(7594):400.

PMID:
26399828
50.

Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression.

Anderson H, Patch TC, Reddy PN, Hagedorn EJ, Kim PG, Soltis KA, Chen MJ, Tamplin OJ, Frye M, MacLean GA, Hübner K, Bauer DE, Kanki JP, Vogin G, Huston NC, Nguyen M, Fujiwara Y, Paw BH, Vestweber D, Zon LI, Orkin SH, Daley GQ, Shah DI.

Blood. 2015 Dec 24;126(26):2811-20. doi: 10.1182/blood-2015-07-659276. Epub 2015 Sep 18.

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