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Items: 1 to 50 of 61

1.

Dissecting Allo-Sensitization After Local Administration of Human Allogeneic Adipose Mesenchymal Stem Cells in Perianal Fistulas of Crohn's Disease Patients.

Avivar-Valderas A, Martín-Martín C, Ramírez C, Del Río B, Menta R, Mancheño-Corvo P, Ortiz-Virumbrales M, Herrero-Méndez Á, Panés J, García-Olmo D, Castañer JL, Palacios I, Lombardo E, Dalemans W, DelaRosa O.

Front Immunol. 2019 Jun 14;10:1244. doi: 10.3389/fimmu.2019.01244. eCollection 2019.

2.

Human Adipose-Derived Mesenchymal Stem Cells Modify Lung Immunity and Improve Antibacterial Defense in Pneumosepsis Caused by Klebsiella pneumoniae.

Perlee D, de Vos AF, Scicluna BP, Mancheño P, de la Rosa O, Dalemans W, Nürnberg P, Lombardo E, van der Poll T.

Stem Cells Transl Med. 2019 Aug;8(8):785-796. doi: 10.1002/sctm.18-0260. Epub 2019 Apr 29.

3.

Human cardiac stem cells inhibit lymphocyte proliferation through paracrine mechanisms that correlate with indoleamine 2,3-dioxygenase induction and activity.

Sebastião MJ, Menta R, Serra M, Palacios I, Alves PM, Sanchez B, DelaRosa O, Dalemans W, Lombardo E, Gomes-Alves P.

Stem Cell Res Ther. 2018 Oct 25;9(1):290. doi: 10.1186/s13287-018-1010-2.

4.

Intravenous Infusion of Human Adipose Mesenchymal Stem Cells Modifies the Host Response to Lipopolysaccharide in Humans: A Randomized, Single-Blind, Parallel Group, Placebo Controlled Trial.

Perlee D, van Vught LA, Scicluna BP, Maag A, Lutter R, Kemper EM, van 't Veer C, Punchard MA, González J, Richard MP, Dalemans W, Lombardo E, de Vos AF, van der Poll T.

Stem Cells. 2018 Nov;36(11):1778-1788. doi: 10.1002/stem.2891. Epub 2018 Aug 20.

PMID:
30063804
5.

Comparative Analysis between the In Vivo Biodistribution and Therapeutic Efficacy of Adipose-Derived Mesenchymal Stromal Cells Administered Intraperitoneally in Experimental Colitis.

Lopez-Santalla M, Mancheño-Corvo P, Escolano A, Menta R, Delarosa O, Redondo JM, Bueren JA, Dalemans W, Lombardo E, Garin MI.

Int J Mol Sci. 2018 Jun 23;19(7). pii: E1853. doi: 10.3390/ijms19071853.

6.

Human Cardiac-Derived Stem/Progenitor Cells Fine-Tune Monocyte-Derived Descendants Activities toward Cardiac Repair.

Dam N, Hocine HR, Palacios I, DelaRosa O, Menta R, Charron D, Bensussan A, El Costa H, Jabrane-Ferrat N, Dalemans W, Lombardo E, Al-Daccak R.

Front Immunol. 2017 Oct 26;8:1413. doi: 10.3389/fimmu.2017.01413. eCollection 2017.

7.

Biodistribution and Efficacy of Human Adipose-Derived Mesenchymal Stem Cells Following Intranodal Administration in Experimental Colitis.

Lopez-Santalla M, Mancheño-Corvo P, Escolano A, Menta R, DelaRosa O, Abad JL, Büscher D, Redondo JM, Bueren JA, Dalemans W, Lombardo E, Garin MI.

Front Immunol. 2017 Jun 8;8:638. doi: 10.3389/fimmu.2017.00638. eCollection 2017.

8.

Intralymphatic Administration of Adipose Mesenchymal Stem Cells Reduces the Severity of Collagen-Induced Experimental Arthritis.

Mancheño-Corvo P, Lopez-Santalla M, Menta R, DelaRosa O, Mulero F, Del Rio B, Ramirez C, Büscher D, Bueren JA, Lopez-Belmonte J, Dalemans W, Garin MI, Lombardo E.

Front Immunol. 2017 Apr 21;8:462. doi: 10.3389/fimmu.2017.00462. eCollection 2017.

9.

Identification of Potential Plasma microRNA Stratification Biomarkers for Response to Allogeneic Adipose-Derived Mesenchymal Stem Cells in Rheumatoid Arthritis.

Mallinson DJ, Dunbar DR, Ridha S, Sutton ER, De la Rosa O, Dalemans W, Lombardo E.

Stem Cells Transl Med. 2017 Apr;6(4):1202-1206. doi: 10.1002/sctm.16-0356. Epub 2017 Jan 3.

10.

Adipose-derived mesenchymal stromal cells modulate experimental autoimmune arthritis by inducing an early regulatory innate cell signature.

Lopez-Santalla M, Menta R, Mancheño-Corvo P, Lopez-Belmonte J, DelaRosa O, Bueren JA, Dalemans W, Lombardo E, Garin MI.

Immun Inflamm Dis. 2016 Apr 4;4(2):213-224. eCollection 2016 Jun.

11.

Human Adipose-Derived Mesenchymal Stem Cells Modulate Experimental Autoimmune Arthritis by Modifying Early Adaptive T Cell Responses.

Lopez-Santalla M, Mancheño-Corvo P, Menta R, Lopez-Belmonte J, DelaRosa O, Bueren JA, Dalemans W, Lombardo E, Garin MI.

Stem Cells. 2015 Dec;33(12):3493-503. doi: 10.1002/stem.2113. Epub 2015 Aug 18.

12.

T Lymphocyte Prestimulation Impairs in a Time-Dependent Manner the Capacity of Adipose Mesenchymal Stem Cells to Inhibit Proliferation: Role of Interferon γ, Poly I:C, and Tryptophan Metabolism in Restoring Adipose Mesenchymal Stem Cell Inhibitory Effect.

Mancheño-Corvo P, Menta R, del Río B, Franquesa M, Ramírez C, Hoogduijn MJ, DelaRosa O, Dalemans W, Lombardo E.

Stem Cells Dev. 2015 Sep 15;24(18):2158-70. doi: 10.1089/scd.2014.0508. Epub 2015 Jun 24.

PMID:
26058889
13.

Mesenchymal stem cells as a therapeutic tool to treat sepsis.

Lombardo E, van der Poll T, DelaRosa O, Dalemans W.

World J Stem Cells. 2015 Mar 26;7(2):368-79. doi: 10.4252/wjsc.v7.i2.368. Review.

14.

Survival and biodistribution of xenogenic adipose mesenchymal stem cells is not affected by the degree of inflammation in arthritis.

Toupet K, Maumus M, Luz-Crawford P, Lombardo E, Lopez-Belmonte J, van Lent P, Garin MI, van den Berg W, Dalemans W, Jorgensen C, Noël D.

PLoS One. 2015 Jan 5;10(1):e0114962. doi: 10.1371/journal.pone.0114962. eCollection 2015. Erratum in: PLoS One. 2015;10(3):e0120406.

15.

Immunomodulatory Potential of Human Adipose Mesenchymal Stem Cells Derived Exosomes on in vitro Stimulated T Cells.

Blazquez R, Sanchez-Margallo FM, de la Rosa O, Dalemans W, Alvarez V, Tarazona R, Casado JG.

Front Immunol. 2014 Nov 4;5:556. doi: 10.3389/fimmu.2014.00556. eCollection 2014.

16.

Human adipose tissue-derived mesenchymal stromal cells promote B-cell motility and chemoattraction.

Barrio L, Cuevas VD, Menta R, Mancheño-Corvo P, delaRosa O, Dalemans W, Lombardo E, Carrasco YR.

Cytotherapy. 2014 Dec;16(12):1692-9. doi: 10.1016/j.jcyt.2014.07.012. Epub 2014 Sep 17.

PMID:
25240680
17.

Tryptophan concentration is the main mediator of the capacity of adipose mesenchymal stromal cells to inhibit T-lymphocyte proliferation in vitro.

Menta R, Mancheño-Corvo P, Del Río B, Ramírez C, DelaRosa O, Dalemans W, Lombardo E.

Cytotherapy. 2014 Dec;16(12):1679-91. doi: 10.1016/j.jcyt.2014.07.004. Epub 2014 Sep 16.

PMID:
25239492
18.

White paper on how to go forward with cell-based advanced therapies in Europe.

Erben RG, Silva-Lima B, Reischl I, Steinhoff G, Tiedemann G, Dalemans W, Vos A, Janssen RT, Le Blanc K, van Osch GJ, Luyten FP.

Tissue Eng Part A. 2014 Oct;20(19-20):2549-54. doi: 10.1089/ten.TEA.2013.0589. Epub 2014 Jun 3.

19.

Adipose mesenchymal stromal cell function is not affected by methotrexate and azathioprine.

Mancheño-Corvo P, Franquesa M, de la Rosa O, Ramírez C, García-Benzaquén L, Fernández V, Menta R, Beraza A, Dalemans W, Hoogduijn MJ, Lombardo E.

Biores Open Access. 2013 Dec 1;2(6):431-9. doi: 10.1089/biores.2013.0040.

20.

Toll-like receptors as modulators of mesenchymal stem cells.

Delarosa O, Dalemans W, Lombardo E.

Front Immunol. 2012 Jul 2;3:182. doi: 10.3389/fimmu.2012.00182. eCollection 2012.

21.

Mesenchymal stem cells as therapeutic agents of inflammatory and autoimmune diseases.

DelaRosa O, Dalemans W, Lombardo E.

Curr Opin Biotechnol. 2012 Dec;23(6):978-83. doi: 10.1016/j.copbio.2012.05.005. Epub 2012 Jun 7. Review.

PMID:
22682584
22.

Guidelines for the Design and Conduct of Clinical Studies in Knee Articular Cartilage Repair: International Cartilage Repair Society Recommendations Based on Current Scientific Evidence and Standards of Clinical Care.

Mithoefer K, Saris DB, Farr J, Kon E, Zaslav K, Cole BJ, Ranstam J, Yao J, Shive M, Levine D, Dalemans W, Brittberg M.

Cartilage. 2011 Apr;2(2):100-21. doi: 10.1177/1947603510392913.

23.

Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys.

Reed SG, Coler RN, Dalemans W, Tan EV, DeLa Cruz EC, Basaraba RJ, Orme IM, Skeiky YA, Alderson MR, Cowgill KD, Prieels JP, Abalos RM, Dubois MC, Cohen J, Mettens P, Lobet Y.

Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2301-6. doi: 10.1073/pnas.0712077106. Epub 2009 Feb 2. Erratum in: Proc Natl Acad Sci U S A.2009 May 5;106(18):7678. Dalemans, Wilifred [corrected to Dalemans, Wilfried].

24.

Insect cells as a new substrate for vaccine production.

Dalemans W.

Dev Biol (Basel). 2006;123:235-41; discussion 265-6.

PMID:
16566449
25.

Evaluation of the Mtb72F polyprotein vaccine in a rabbit model of tuberculous meningitis.

Tsenova L, Harbacheuski R, Moreira AL, Ellison E, Dalemans W, Alderson MR, Mathema B, Reed SG, Skeiky YA, Kaplan G.

Infect Immun. 2006 Apr;74(4):2392-401.

26.

Protection of mice and guinea pigs against tuberculosis induced by immunization with a single Mycobacterium tuberculosis recombinant antigen, MTB41.

Skeiky YA, Alderson MR, Ovendale PJ, Lobet Y, Dalemans W, Orme IM, Reed SG, Campos-Neto A.

Vaccine. 2005 Jun 10;23(30):3937-45. Epub 2005 Mar 30.

PMID:
15917115
27.

Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6.

Langermans JA, Doherty TM, Vervenne RA, van der Laan T, Lyashchenko K, Greenwald R, Agger EM, Aagaard C, Weiler H, van Soolingen D, Dalemans W, Thomas AW, Andersen P.

Vaccine. 2005 Apr 15;23(21):2740-50.

PMID:
15780721
28.

Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis.

Williams A, Hatch GJ, Clark SO, Gooch KE, Hatch KA, Hall GA, Huygen K, Ottenhoff TH, Franken KL, Andersen P, Doherty TM, Kaufmann SH, Grode L, Seiler P, Martin C, Gicquel B, Cole ST, Brodin P, Pym AS, Dalemans W, Cohen J, Lobet Y, Goonetilleke N, McShane H, Hill A, Parish T, Smith D, Stoker NG, Lowrie DB, Källenius G, Svenson S, Pawlowski A, Blake K, Marsh PD.

Tuberculosis (Edinb). 2005 Jan-Mar;85(1-2):29-38. Epub 2005 Jan 20.

PMID:
15687025
29.

The protective effect of the Mycobacterium bovis BCG vaccine is increased by coadministration with the Mycobacterium tuberculosis 72-kilodalton fusion polyprotein Mtb72F in M. tuberculosis-infected guinea pigs.

Brandt L, Skeiky YA, Alderson MR, Lobet Y, Dalemans W, Turner OC, Basaraba RJ, Izzo AA, Lasco TM, Chapman PL, Reed SG, Orme IM.

Infect Immun. 2004 Nov;72(11):6622-32.

30.

In vitro cellular immune responses to complex and newly defined recombinant antigens of Mycobacterium tuberculosis.

Al-Attiyah R, Mustafa AS, Abal AT, El-Shamy AS, Dalemans W, Skeiky YA.

Clin Exp Immunol. 2004 Oct;138(1):139-44.

31.

Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine, Mtb72F, delivered as naked DNA or recombinant protein.

Skeiky YA, Alderson MR, Ovendale PJ, Guderian JA, Brandt L, Dillon DC, Campos-Neto A, Lobet Y, Dalemans W, Orme IM, Reed SG.

J Immunol. 2004 Jun 15;172(12):7618-28.

32.

Immune responses to mycobacterial antigens in the Gambian population: implications for vaccines and immunodiagnostic test design.

Vekemans J, Ota MO, Sillah J, Fielding K, Alderson MR, Skeiky YA, Dalemans W, McAdam KP, Lienhardt C, Marchant A.

Infect Immun. 2004 Jan;72(1):381-8.

33.

Prospects for a better vaccine against tuberculosis.

Reed SG, Alderson MR, Dalemans W, Lobet Y, Skeiky YA.

Tuberculosis (Edinb). 2003;83(1-3):213-9. Review.

PMID:
12758214
34.

Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting.

Tanghe A, D'Souza S, Rosseels V, Denis O, Ottenhoff TH, Dalemans W, Wheeler C, Huygen K.

Infect Immun. 2001 May;69(5):3041-7.

35.

Intra-pinna anti-tumor vaccination with self-replicating infectious RNA or with DNA encoding a model tumor antigen and a cytokine.

Schirmacher V, Förg P, Dalemans W, Chlichlia K, Zeng Y, Fournier P, von Hoegen P.

Gene Ther. 2000 Jul;7(13):1137-47.

36.

Molecular characterization and human T-cell responses to a member of a novel Mycobacterium tuberculosis mtb39 gene family.

Dillon DC, Alderson MR, Day CH, Lewinsohn DM, Coler R, Bement T, Campos-Neto A, Skeiky YA, Orme IM, Roberts A, Steen S, Dalemans W, Badaro R, Reed SG.

Infect Immun. 1999 Jun;67(6):2941-50.

37.

Superiority of the ear pinna over muscle tissue as site for DNA vaccination.

Förg P, von Hoegen P, Dalemans W, Schirrmacher V.

Gene Ther. 1998 Jun;5(6):789-97.

38.

Protection against homologous influenza challenge by genetic immunization with SFV-RNA encoding Flu-HA.

Dalemans W, Delers A, Delmelle C, Denamur F, Meykens R, Thiriart C, Veenstra S, Francotte M, Bruck C, Cohen J.

Ann N Y Acad Sci. 1995 Nov 27;772:255-6. No abstract available.

PMID:
8546401
39.

A change in gating mode leading to increased intrinsic Cl- channel activity compensates for defective processing in a cystic fibrosis mutant corresponding to a mild form of the disease.

Champigny G, Imler JL, Puchelle E, Dalemans W, Gribkoff V, Hinnrasky J, Dott K, Barbry P, Pavirani A, Lazdunski M.

EMBO J. 1995 Jun 1;14(11):2417-23.

40.

Autocrine mitogen IgEGF cooperates with c-myc or with the Hcs locus during hepatocarcinogenesis in transgenic mice.

Tönjes RR, Löhler J, O'Sullivan JF, Kay GF, Schmidt GH, Dalemans W, Pavirani A, Paul D.

Oncogene. 1995 Feb 16;10(4):765-8.

PMID:
7862454
41.

Immunohistochemical localization of cystic fibrosis transmembrane conductance regulator in human fetal airway and digestive mucosa.

Gaillard D, Ruocco S, Lallemand A, Dalemans W, Hinnrasky J, Puchelle E.

Pediatr Res. 1994 Aug;36(2):137-43.

PMID:
7526324
42.

From in vitro to in vivo. Progress in the use of cultured cells for human therapy.

Dalemans W.

Cytotechnology. 1994;16(3):189-94. Review.

PMID:
7766147
43.

Low-conductance chloride channels in IEC-6 and CF nasal cells expressing CFTR.

Bijman J, Dalemans W, Kansen M, Keulemans J, Verbeek E, Hoogeveen A, De Jonge H, Wilke M, Dreyer D, Lecocq JP, et al.

Am J Physiol. 1993 Mar;264(3 Pt 1):L229-35.

PMID:
7681632
44.

Differential localization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis airway epithelium.

Puchelle E, Gaillard D, Ploton D, Hinnrasky J, Fuchey C, Boutterin MC, Jacquot J, Dreyer D, Pavirani A, Dalemans W.

Am J Respir Cell Mol Biol. 1992 Nov;7(5):485-91.

PMID:
1384582
45.

Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C.

Bargon J, Trapnell BC, Yoshimura K, Dalemans W, Pavirani A, Lecocq JP, Crystal RG.

J Biol Chem. 1992 Aug 15;267(23):16056-60.

46.

A 17.6 kbp region located upstream of the rabbit WAP gene directs high level expression of a functional human protein variant in transgenic mouse milk.

Bischoff R, Degryse E, Perraud F, Dalemans W, Ali-Hadji D, Thépot D, Devinoy E, Houdebine LM, Pavirani A.

FEBS Lett. 1992 Jul 6;305(3):265-8.

47.

Immunocytochemical analysis reveals differences between the subcellular localization of normal and delta Phe508 recombinant cystic fibrosis transmembrane conductance regulator.

Dalemans W, Hinnrasky J, Slos P, Dreyer D, Fuchey C, Pavirani A, Puchelle E.

Exp Cell Res. 1992 Jul;201(1):235-40.

PMID:
1377133
48.

The promoter of the human cystic fibrosis transmembrane conductance regulator gene directing SV40 T antigen expression induces malignant proliferation of ependymal cells in transgenic mice.

Perraud F, Yoshimura K, Louis B, Dalemans W, Ali-Hadji D, Schultz H, Claudepierre MC, Chartier C, Danel C, Bellocq JP, et al.

Oncogene. 1992 May;7(5):993-7.

PMID:
1373882
49.

Down-regulation of cystic fibrosis transmembrane conductance regulator gene expression by agents that modulate intracellular divalent cations.

Bargon J, Trapnell BC, Chu CS, Rosenthal ER, Yoshimura K, Guggino WB, Dalemans W, Pavirani A, Lecocq JP, Crystal RG.

Mol Cell Biol. 1992 Apr;12(4):1872-8.

50.

In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium.

Rosenfeld MA, Yoshimura K, Trapnell BC, Yoneyama K, Rosenthal ER, Dalemans W, Fukayama M, Bargon J, Stier LE, Stratford-Perricaudet L, et al.

Cell. 1992 Jan 10;68(1):143-55.

PMID:
1370653

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