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Items: 1 to 50 of 133

1.

Epitope-specific CD8+ T cells play a differential pathogenic role in the development of a viral disease model for multiple sclerosis.

Myoung J, Kang HS, Hou W, Meng L, Dal Canto MC, Kim BS.

J Virol. 2012 Dec;86(24):13717-28. doi: 10.1128/JVI.01733-12. Epub 2012 Oct 10.

2.

Molecular dissection of ALS-associated toxicity of SOD1 in transgenic mice using an exon-fusion approach.

Deng HX, Jiang H, Fu R, Zhai H, Shi Y, Liu E, Hirano M, Dal Canto MC, Siddique T.

Hum Mol Genet. 2008 Aug 1;17(15):2310-9. doi: 10.1093/hmg/ddn131. Epub 2008 Apr 18. Erratum in: Hum Mol Genet. 2009 Feb 1;18(3):594. Han-Xiang, Deng [corrected to Deng, Han-Xiang]; Hujun, Jiang [corrected to Jiang, Hujun]; Ronggen, Fu [corrected to Fu, Ronggen]; Hong, Zhai [corrected to Zhai, Hong]; Yong, Shi [corrected to Shi, Yong]; Erdong, Liu [corrected to Liu, Erdong]; Makito, Hira.

3.

Anticapsid immunity level, not viral persistence level, correlates with the progression of Theiler's virus-induced demyelinating disease in viral P1-transgenic mice.

Myoung J, Bahk YY, Kang HS, Dal Canto MC, Kim BS.

J Virol. 2008 Jun;82(11):5606-17. doi: 10.1128/JVI.02442-07. Epub 2008 Mar 19.

4.

Distal axonopathy in an alsin-deficient mouse model.

Deng HX, Zhai H, Fu R, Shi Y, Gorrie GH, Yang Y, Liu E, Dal Canto MC, Mugnaini E, Siddique T.

Hum Mol Genet. 2007 Dec 1;16(23):2911-20. Epub 2007 Sep 12.

PMID:
17855450
5.

CCR2 regulates development of Theiler's murine encephalomyelitis virus-induced demyelinating disease.

Bennett JL, Elhofy A, Charo I, Miller SD, Dal Canto MC, Karpus WJ.

Viral Immunol. 2007 Spring;20(1):19-33.

PMID:
17425418
6.

Anti-CCL2 treatment inhibits Theiler's murine encephalomyelitis virus-induced demyelinating disease.

Karpus WJ, Kennedy KJ, Fife BT, Bennett JL, Dal Canto MC, Kunkel SL, Lukacs NW.

J Neurovirol. 2006 Aug;12(4):251-61.

7.

Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria.

Deng HX, Shi Y, Furukawa Y, Zhai H, Fu R, Liu E, Gorrie GH, Khan MS, Hung WY, Bigio EH, Lukas T, Dal Canto MC, O'Halloran TV, Siddique T.

Proc Natl Acad Sci U S A. 2006 May 2;103(18):7142-7. Epub 2006 Apr 24.

8.

Gender bias in Theiler's virus-induced demyelinating disease correlates with the level of antiviral immune responses.

Fuller AC, Kang B, Kang HK, Yahikozowa H, Dal Canto MC, Kim BS.

J Immunol. 2005 Sep 15;175(6):3955-63.

9.

Molecular biological approaches to neurological disorders including knockout and transgenic mouse models.

Shibata N, Oda H, Hirano A, Kato Y, Kawaguchi M, Dal Canto MC, Uchida K, Sawada T, Kobayashi M.

Neuropathology. 2002 Dec;22(4):337-49. Review.

PMID:
12564775
10.

CD154 blockade results in transient reduction in Theiler's murine encephalomyelitis virus-induced demyelinating disease.

Howard LM, Neville KL, Haynes LM, Dal Canto MC, Miller SD.

J Virol. 2003 Feb;77(3):2247-50.

12.

Selective formation of certain advanced glycation end products in spinal cord astrocytes of humans and mice with superoxide dismutase-1 mutation.

Shibata N, Hirano A, Hedley-Whyte ET, Dal Canto MC, Nagai R, Uchida K, Horiuchi S, Kawaguchi M, Yamamoto T, Kobayashi M.

Acta Neuropathol. 2002 Aug;104(2):171-8. Epub 2002 Apr 18.

PMID:
12111360
13.

De novo central nervous system processing of myelin antigen is required for the initiation of experimental autoimmune encephalomyelitis.

Tompkins SM, Padilla J, Dal Canto MC, Ting JP, Van Kaer L, Miller SD.

J Immunol. 2002 Apr 15;168(8):4173-83.

14.

CD40/CD40L interaction is essential for the induction of EAE in the absence of CD28-mediated co-stimulation.

Girvin AM, Dal Canto MC, Miller SD.

J Autoimmun. 2002 Mar;18(2):83-94.

PMID:
11908941
15.

Normal Th1 development following long-term therapeutic blockade of CD154-CD40 in experimental autoimmune encephalomyelitis.

Howard LM, Ostrovidov S, Smith CE, Dal Canto MC, Miller SD.

J Clin Invest. 2002 Jan;109(2):233-41.

16.

Transcription from the gene encoding the herpesvirus entry receptor nectin-1 (HveC) in nervous tissue of adult mouse.

Haarr L, Shukla D, Rødahl E, Dal Canto MC, Spear PG.

Virology. 2001 Sep 1;287(2):301-9.

18.

A virus-induced molecular mimicry model of multiple sclerosis.

Olson JK, Croxford JL, Calenoff MA, Dal Canto MC, Miller SD.

J Clin Invest. 2001 Jul;108(2):311-8.

20.

Divergent roles for p55 and p75 tumor necrosis factor receptors in the pathogenesis of MOG(35-55)-induced experimental autoimmune encephalomyelitis.

Suvannavejh GC, Lee HO, Padilla J, Dal Canto MC, Barrett TA, Miller SD.

Cell Immunol. 2000 Oct 10;205(1):24-33.

PMID:
11078604
21.

HIV-1 and its causal relationship to immunosuppression and nervous system disease in AIDS: a review.

Sotrel A, Dal Canto MC.

Hum Pathol. 2000 Oct;31(10):1274-98. Review.

PMID:
11070121
22.
23.

CD8(+) T cells from Theiler's virus-resistant BALB/cByJ mice downregulate pathogenic virus-specific CD4(+) T cells.

Haynes LM, Vanderlugt CL, Dal Canto MC, Melvold RW, Miller SD.

J Neuroimmunol. 2000 Jul 1;106(1-2):43-52.

PMID:
10814781
24.

Treatment of established relapsing experimental autoimmune encephalomyelitis with the proteasome inhibitor PS-519.

Vanderlugt CL, Rahbe SM, Elliott PJ, Dal Canto MC, Miller SD.

J Autoimmun. 2000 May;14(3):205-11.

PMID:
10756082
26.

Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis.

Suvannavejh GC, Dal Canto MC, Matis LA, Miller SD.

J Clin Invest. 2000 Jan;105(2):223-31.

27.
29.

Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis.

Howard LM, Miga AJ, Vanderlugt CL, Dal Canto MC, Laman JD, Noelle RJ, Miller SD.

J Clin Invest. 1999 Jan;103(2):281-90.

30.

Presence of Cu/Zn superoxide dismutase (SOD) immunoreactivity in neuronal hyaline inclusions in spinal cords from mice carrying a transgene for Gly93Ala mutant human Cu/Zn SOD.

Shibata N, Hirano A, Kobayashi M, Dal Canto MC, Gurney ME, Komori T, Umahara T, Asayama K.

Acta Neuropathol. 1998 Feb;95(2):136-42.

PMID:
9498047
31.

A spontaneous low-pathogenic variant of Theiler's virus contains an amino acid substitution within the predominant VP1(233-250) T-cell epitope.

Kim BS, Yauch RL, Bahk YY, Kang JA, Dal Canto MC, Hall CK.

J Virol. 1998 Feb;72(2):1020-7. Erratum in: J Virol 1998 Aug;72(8):6965.

32.

Treatment with intact anti-B7-1 mAb during disease remission enhances epitope spreading and exacerbates relapses in R-EAE.

Vanderlugt CL, Karandikar NJ, Lenschow DJ, Dal Canto MC, Bluestone JA, Miller SD.

J Neuroimmunol. 1997 Nov;79(2):113-8.

PMID:
9394783
34.

Mechanisms of HIV infection of the central nervous system and pathogenesis of AIDS-dementia complex.

Dal Canto MC.

Neuroimaging Clin N Am. 1997 May;7(2):231-41. Review.

PMID:
9113688
35.

Theiler's Murine Encephalomyelitis Virus (TMEV)-Induced Demyelination: A Model for Human Multiple Sclerosis

Dal Canto MC, Kim BS, Miller SD, Melvold RW.

Methods. 1996 Dec;10(3):453-61.

PMID:
8954856
36.
37.
38.

The Golgi apparatus and the pathogenesis of Alzheimer's disease.

Dal Canto MC.

Am J Pathol. 1996 Feb;148(2):355-60. Review. No abstract available.

39.

Adoptively transferred CD8+ T lymphocytes provide protection against TMEV-induced demyelinating disease in BALB/c mice.

Nicholson SM, Dal Canto MC, Miller SD, Melvold RW.

J Immunol. 1996 Feb 1;156(3):1276-83.

PMID:
8558008
40.

Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE.

Miller SD, Vanderlugt CL, Lenschow DJ, Pope JG, Karandikar NJ, Dal Canto MC, Bluestone JA.

Immunity. 1995 Dec;3(6):739-45.

41.

Treatment with bacterial LPS renders genetically resistant C57BL/6 mice susceptible to Theiler's virus-induced demyelinating disease.

Pullen LC, Park SH, Miller SD, Dal Canto MC, Kim BS.

J Immunol. 1995 Nov 1;155(9):4497-503.

PMID:
7594613
44.

The leader polypeptide of Theiler's virus is essential for neurovirulence but not for virus growth in BHK cells.

Calenoff MA, Badshah CS, Dal Canto MC, Lipton HL, Rundell MK.

J Virol. 1995 Sep;69(9):5544-9.

45.

Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis.

Chiu AY, Zhai P, Dal Canto MC, Peters TM, Kwon YW, Prattis SM, Gurney ME.

Mol Cell Neurosci. 1995 Aug;6(4):349-62.

PMID:
8846004
46.

Inhibition of Theiler's virus-mediated demyelination by peripheral immune tolerance induction.

Karpus WJ, Pope JG, Peterson JD, Dal Canto MC, Miller SD.

J Immunol. 1995 Jul 15;155(2):947-57. Erratum in: J Immunol 1996 Apr 15;156(8):following 3088.

PMID:
7608570
47.

Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis.

McRae BL, Vanderlugt CL, Dal Canto MC, Miller SD.

J Exp Med. 1995 Jul 1;182(1):75-85.

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