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Items: 1 to 50 of 70

1.

Purification, structural elucidation, antioxidant capacity and neuroprotective potential of the main polyphenolic compounds contained in Achyrocline satureioides (Lam) D.C. (Compositae).

Martínez-Busi M, Arredondo F, González D, Echeverry C, Vega-Teijido MA, Carvalho D, Rodríguez-Haralambides A, Rivera F, Dajas F, Abin-Carriquiry JA.

Bioorg Med Chem. 2019 Jun 15;27(12):2579-2591. doi: 10.1016/j.bmc.2019.03.047. Epub 2019 Mar 25.

PMID:
30935792
2.

Nicotine-Induced Neuroprotection in Rotenone In Vivo and In Vitro Models of Parkinson's Disease: Evidences for the Involvement of the Labile Iron Pool Level as the Underlying Mechanism.

Mouhape C, Costa G, Ferreira M, Abin-Carriquiry JA, Dajas F, Prunell G.

Neurotox Res. 2019 Jan;35(1):71-82. doi: 10.1007/s12640-018-9931-1. Epub 2018 Jul 13.

PMID:
30006684
3.

Intravenous nanosomes of quercetin improve brain function and hemodynamic instability after severe hypoxia in newborn piglets.

Blasina F, Vaamonde L, Silvera F, Tedesco AC, Dajas F.

Neurochem Int. 2015 Oct;89:149-56. doi: 10.1016/j.neuint.2015.08.007. Epub 2015 Aug 19.

PMID:
26297982
4.

Quercetin in brain diseases: Potential and limits.

Dajas F, Abin-Carriquiry JA, Arredondo F, Blasina F, Echeverry C, Martínez M, Rivera F, Vaamonde L.

Neurochem Int. 2015 Oct;89:140-8. doi: 10.1016/j.neuint.2015.07.002. Epub 2015 Jul 6. Review.

PMID:
26160469
5.

Antioxidant activity, cellular bioavailability, and iron and calcium management of neuroprotective and nonneuroprotective flavones.

Echeverry C, Arredondo F, Martínez M, Abin-Carriquiry JA, Midiwo J, Dajas F.

Neurotox Res. 2015 Jan;27(1):31-42. doi: 10.1007/s12640-014-9483-y. Epub 2014 Jun 28.

PMID:
24972590
6.

Neuroprotective actions of flavones and flavonols: mechanisms and relationship to flavonoid structural features.

Dajas F, Andrés AC, Florencia A, Carolina E, Felicia RM.

Cent Nerv Syst Agents Med Chem. 2013 Mar;13(1):30-5. Review.

PMID:
23092407
7.

Life or death: neuroprotective and anticancer effects of quercetin.

Dajas F.

J Ethnopharmacol. 2012 Sep 28;143(2):383-96. doi: 10.1016/j.jep.2012.07.005. Epub 2012 Jul 20. Review.

PMID:
22820241
8.

After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult.

Arredondo F, Echeverry C, Abin-Carriquiry JA, Blasina F, Antúnez K, Jones DP, Go YM, Liang YL, Dajas F.

Free Radic Biol Med. 2010 Sep 1;49(5):738-47. doi: 10.1016/j.freeradbiomed.2010.05.020. Epub 2010 Jun 8.

PMID:
20554019
9.

In silico characterization of cytisinoids docked into an acetylcholine binding protein.

Abin-Carriquiry JA, Zunini MP, Cassels BK, Wonnacott S, Dajas F.

Bioorg Med Chem Lett. 2010 Jun 15;20(12):3683-7. doi: 10.1016/j.bmcl.2010.04.092. Epub 2010 May 6.

PMID:
20493692
10.

Increase in locomotor activity after acute administration of the nicotinic receptor agonist 3-bromocytisine in rats.

Abin-Carriquiry JA, Urbanavicius J, Scorza C, Rebolledo-Fuentes M, Wonnacott S, Cassels BK, Dajas F.

Eur J Pharmacol. 2010 May 25;634(1-3):89-94. doi: 10.1016/j.ejphar.2010.02.030. Epub 2010 Feb 23.

PMID:
20184877
11.

Pretreatment with natural flavones and neuronal cell survival after oxidative stress: a structure-activity relationship study.

Echeverry C, Arredondo F, Abin-Carriquiry JA, Midiwo JO, Ochieng C, Kerubo L, Dajas F.

J Agric Food Chem. 2010 Feb 24;58(4):2111-5. doi: 10.1021/jf902951v.

PMID:
20095615
12.

Differentiation induced by Achyrocline satureioides (Lam) infusion in PC12 cells.

Blasina MF, Vaamonde L, Morquio A, Echeverry C, Arredondo F, Dajas F.

Phytother Res. 2009 Sep;23(9):1263-9. doi: 10.1002/ptr.2607.

PMID:
19370542
13.

In vivo modulation of dopaminergic nigrostriatal pathways by cytisine derivatives: implications for Parkinson's Disease.

Abin-Carriquiry JA, Costa G, Urbanavicius J, Cassels BK, Rebolledo-Fuentes M, Wonnacott S, Dajas F.

Eur J Pharmacol. 2008 Jul 28;589(1-3):80-4. doi: 10.1016/j.ejphar.2008.05.013. Epub 2008 May 20.

PMID:
18589414
14.

Reduction of ischemic brain damage and increase of glutathione by a liposomal preparation of quercetin in permanent focal ischemia in rats.

Rivera F, Costa G, Abin A, Urbanavicius J, Arruti C, Casanova G, Dajas F.

Neurotox Res. 2008 Apr;13(2):105-14.

PMID:
18515213
15.

Immunomodulatory properties of Achyrocline satureioides (Lam.) D.C. infusion: a study on human leukocytes.

Cosentino M, Bombelli R, Carcano E, Luini A, Marino F, Crema F, Dajas F, Lecchini S.

J Ethnopharmacol. 2008 Mar 28;116(3):501-7. doi: 10.1016/j.jep.2007.12.014. Epub 2008 Jan 6.

PMID:
18280072
16.

Nicotine induces tyrosine hydroxylase plasticity in the neurodegenerating striatum.

Urbanavicius J, Ferreira M, Costa G, Abin-Carriquiry JA, Wonnacott S, Dajas F.

J Neurochem. 2007 Aug;102(3):723-30. Epub 2007 Apr 16.

17.

C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists.

Abin-Carriquiry JA, Voutilainen MH, Barik J, Cassels BK, Iturriaga-Vásquez P, Bermudez I, Durand C, Dajas F, Wonnacott S.

Eur J Pharmacol. 2006 Apr 24;536(1-2):1-11. Epub 2006 Mar 6.

PMID:
16563372
18.

From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research.

Cassels BK, Bermúdez I, Dajas F, Abin-Carriquiry JA, Wonnacott S.

Drug Discov Today. 2005 Dec;10(23-24):1657-65. Review.

PMID:
16376826
19.

Photoprotection by topical application of Achyrocline satureioides ('Marcela').

Morquio A, Rivera-Megret F, Dajas F.

Phytother Res. 2005 Jun;19(6):486-90.

PMID:
16114090
20.

Some aspects of the in vivo neuroprotective capacity of flavonoids: bioavailability and structure-activity relationship.

Rivera F, Urbanavicius J, Gervaz E, Morquio A, Dajas F.

Neurotox Res. 2004;6(7-8):543-53.

PMID:
15639786
21.

Cytoprotection by neutral fraction of tannat red wine against oxidative stress-induced cell death.

Echeverry C, Blasina F, Arredondo F, Ferreira M, Abin-Carriquiry JA, Vasquez L, Aspillaga AA, Diez MS, Leighton F, Dajas F.

J Agric Food Chem. 2004 Dec 1;52(24):7395-9.

PMID:
15563225
22.

Toxicological studies of the aqueous extract from Achyrocline satureioides (Lam.) DC (Marcela).

Rivera F, Gervaz E, Sere C, Dajas F.

J Ethnopharmacol. 2004 Dec;95(2-3):359-62.

PMID:
15507360
23.

Cytoprotection by Achyrocline satureioides (Lam) D.C. and some of its main flavonoids against oxidative stress.

Arredondo MF, Blasina F, Echeverry C, Morquio A, Ferreira M, Abin-Carriquiry JA, Lafon L, Dajas F.

J Ethnopharmacol. 2004 Mar;91(1):13-20.

PMID:
15036461
24.

Cell culture protection and in vivo neuroprotective capacity of flavonoids.

Dajas F, Rivera F, Blasina F, Arredondo F, Echeverry C, Lafon L, Morquio A, Heinzen H.

Neurotox Res. 2003;5(6):425-32. Erratum in: Neurotox Res. 2013 Nov;24(4):560. Heizen, Horacio [corrected to Heinzen, Horacio].

PMID:
14715446
25.

Neuroprotection by flavonoids.

Dajas F, Rivera-Megret F, Blasina F, Arredondo F, Abin-Carriquiry JA, Costa G, Echeverry C, Lafon L, Heizen H, Ferreira M, Morquio A.

Braz J Med Biol Res. 2003 Dec;36(12):1613-20. Epub 2003 Nov 17. Review.

26.

Presynaptic involvement in the nicotine prevention of the dopamine loss provoked by 6-OHDA administration in the substantia nigra.

Abin-Carriquiry JA, McGregor-Armas R, Costa G, Urbanavicius J, Dajas F.

Neurotox Res. 2002 Mar;4(2):133-9.

PMID:
12829413
27.

Screening of antioxidant activity of three Indian medicinal plants, traditionally used for the management of neurodegenerative diseases.

Auddy B, Ferreira M, Blasina F, Lafon L, Arredondo F, Dajas F, Tripathi PC, Seal T, Mukherjee B.

J Ethnopharmacol. 2003 Feb;84(2-3):131-8.

PMID:
12648805
28.

Antioxidant and cholinergic neuroprotective mechanisms in experimental parkinsonism.

Dajas F, Costa G, Abin-Carriquiry JA, Echeverry C, Martínez-Borges A, Dajas-Bailador F.

Funct Neurol. 2002 Jan-Mar;17(1):37-44. Review. No abstract available.

PMID:
12086112
29.

Involvement of nicotinic acetylcholine receptors in the protection of dopamine terminals in experimental parkinsonism.

Dajas F, Costa G, Abín-Carriquiry JA, McGregor R, Urbanavicius J.

Funct Neurol. 2001;16(4 Suppl):113-23. Review. No abstract available.

PMID:
11996506
30.

Intracerebral administration of 2,4-diclorophenoxyacetic acid induces behavioral and neurochemical alterations in the rat brain.

Bortolozzi A, Evangelista de Duffard AM, Dajas F, Duffard R, Silveira R.

Neurotoxicology. 2001 Apr;22(2):221-32.

PMID:
11405254
31.

Nicotine prevents striatal dopamine loss produced by 6-hydroxydopamine lesion in the substantia nigra.

Costa G, Abin-Carriquiry JA, Dajas F.

Brain Res. 2001 Jan 12;888(2):336-342.

PMID:
11150495
32.

Do structural deviations between toxins adopting the same fold reflect functional differences?

Ricciardi A, le Du MH, Khayati M, Dajas F, Boulain JC, Menez A, Ducancel F.

J Biol Chem. 2000 Jun 16;275(24):18302-10.

33.

Evidence for a noncholinergic function of acetylcholinesterase during development of chicken retina as shown by fasciculin.

Blasina MF, Faria AC, Gardino PF, Hokoc JN, Almeida OM, de Mello FG, Arruti C, Dajas F.

Cell Tissue Res. 2000 Feb;299(2):173-84.

PMID:
10741458
34.

Dopaminergic pharmacology and antioxidant properties of pukateine, a natural product lead for the design of agents increasing dopamine neurotransmission.

Dajas-Bailador FA, Asencio M, Bonilla C, Scorza MC, Echeverry C, Reyes-Parada M, Silveira R, Protais P, Russell G, Cassels BK, Dajas F.

Gen Pharmacol. 1999 Mar;32(3):373-9.

PMID:
10211594
35.
36.

Hydroxyl radical production in the substantia nigra after 6-hydroxydopamine and hypoxia-reoxygenation.

Dajas-Bailador FA, Martinez-Borges A, Costa G, Abin JA, Martignoni E, Nappi G, Dajas F.

Brain Res. 1998 Nov 30;813(1):18-25.

PMID:
9824659
37.

Developmental regulation of mouse brain monomeric acetylcholinesterase.

Moreno RD, Campos FO, Dajas F, Inestrosa NC.

Int J Dev Neurosci. 1998 Apr;16(2):123-34.

PMID:
9762585
38.

Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils.

Alvarez A, Alarcón R, Opazo C, Campos EO, Muñoz FJ, Calderón FH, Dajas F, Gentry MK, Doctor BP, De Mello FG, Inestrosa NC.

J Neurosci. 1998 May 1;18(9):3213-23.

39.

Acetylcholinesterase inhibitors block acetylcholine-evoked release of dopamine in rat striatum, in vivo.

Dajas-Bailador F, Costa G, Emmett S, Bonilla C, Dajas F.

Brain Res. 1996 May 25;722(1-2):12-8.

PMID:
8813345
40.
41.

Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects.

Viola H, Wasowski C, Levi de Stein M, Wolfman C, Silveira R, Dajas F, Medina JH, Paladini AC.

Planta Med. 1995 Jun;61(3):213-6.

PMID:
7617761
42.

Fasciculin inhibition of acetylcholinesterase is prevented by chemical modification of the enzyme at a peripheral site.

Durán R, Cerveñansky C, Dajas F, Tipton KF.

Biochim Biophys Acta. 1994 Dec 15;1201(3):381-8.

PMID:
7803468
43.

Recovery of central noradrenergic neurons one year after the administration of the neurotoxin DSP4.

Wolfman C, Abó V, Calvo D, Medina J, Dajas F, Silveira R.

Neurochem Int. 1994 Oct;25(4):395-400.

PMID:
7820072
44.

Monoamine oxidase inhibitory effects of some 4-aminophenethylamine derivatives.

Reyes-Parada M, Scorza MC, Silveira R, Dajas F, Costa G, Tipton KF, Cassels BK.

Biochem Pharmacol. 1994 Apr 20;47(8):1365-71.

PMID:
7514408
45.

4-Dimethylaminophenethylamine, a sensitive, specific, electrochemically detectable monoamine oxidase-B substrate.

Reyes-Parada M, Scorza MC, Silveira R, Dajas F, Cassels BK.

Life Sci. 1994;54(25):1955-63.

PMID:
8201844
46.

Neurotoxins: nature's untapped bounty.

Wonnacott S, Dajas F.

Trends Pharmacol Sci. 1994 Jan;15(1):1-3. No abstract available. Erratum in: Trends Pharmacol Sci 1994 Sep;15(9):349.

PMID:
8140650
47.

Possible anxiolytic effects of chrysin, a central benzodiazepine receptor ligand isolated from Passiflora coerulea.

Wolfman C, Viola H, Paladini A, Dajas F, Medina JH.

Pharmacol Biochem Behav. 1994 Jan;47(1):1-4.

PMID:
7906886
48.

Differential cholinergic and non-cholinergic actions of acetylcholinesterase in the substantia nigra revealed by fasciculin-induced inhibition.

Dajas F, Silveira R, Costa G, Castello ME, Jerusalinsky D, Medina J, Levesque D, Greenfield S.

Brain Res. 1993 Jul 9;616(1-2):1-5.

PMID:
7689409
49.

Hippocampal and entorhinal glucose metabolism in relation to cholinergic theta rhythm.

Sánchez-Arroyos R, Gaztelu JM, Zaplana J, Dajas F, García-Austt E.

Brain Res Bull. 1993;32(2):171-8.

PMID:
8348341
50.

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