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Items: 13


Biochemical and pharmacological characterization of AZD1981, an orally available selective DP2 antagonist in clinical development for asthma.

Schmidt JA, Bell FM, Akam E, Marshall C, Dainty IA, Heinemann A, Dougall IG, Bonnert RV, Sargent CA.

Br J Pharmacol. 2013 Apr;168(7):1626-38. doi: 10.1111/bph.12053.


Formoterol and salmeterol induce a similar degree of β2-adrenoceptor tolerance in human small airways but via different mechanisms.

Cooper PR, Kurten RC, Zhang J, Nicholls DJ, Dainty IA, Panettieri RA.

Br J Pharmacol. 2011 Jun;163(3):521-32. doi: 10.1111/j.1476-5381.2011.01257.x.


Agonist-specific patterns of beta 2-adrenoceptor responses in human airway cells during prolonged exposure.

Düringer C, Grundström G, Gürcan E, Dainty IA, Lawson M, Korn SH, Jerre A, Håkansson HF, Wieslander E, Fredriksson K, Sköld CM, Löfdahl M, Löfdahl CG, Nicholls DJ, Silberstein DS.

Br J Pharmacol. 2009 Sep;158(1):169-79. doi: 10.1111/j.1476-5381.2009.00262.x. Epub 2009 Jun 22.


Ca(2+) signalling by recombinant human CXCR2 chemokine receptors is potentiated by P2Y nucleotide receptors in HEK cells.

Werry TD, Christie MI, Dainty IA, Wilkinson GF, Willars GB.

Br J Pharmacol. 2002 Mar;135(5):1199-208.


P2Y1-receptors in human platelets which are pharmacologically distinct from P2Y(ADP)-receptors.

Fagura MS, Dainty IA, McKay GD, Kirk IP, Humphries RG, Robertson MJ, Dougall IG, Leff P.

Br J Pharmacol. 1998 May;124(1):157-64.


Cloning and characterisation of a bovine P2Y receptor.

Henderson DJ, Elliot DG, Smith GM, Webb TE, Dainty IA.

Biochem Biophys Res Commun. 1995 Jul 17;212(2):648-56.


Further subclassification of ATP receptors based on agonist studies.

O'Connor SE, Dainty IA, Leff P.

Trends Pharmacol Sci. 1991 Apr;12(4):137-41. Review.


The influence of the initial stretch and the agonist-induced tone on the effect of basal and stimulated release of EDRF.

Dainty IA, McGrath JC, Spedding M, Templeton AG.

Br J Pharmacol. 1990 Aug;100(4):767-73.


Interactions of palmitoyl carnitine with the endothelium in rat aorta.

Dainty IA, Bigaud M, McGrath JC, Spedding M.

Br J Pharmacol. 1990 Jun;100(2):241-6.


Errors in agonist affinity estimation: do they and should they occur in isolated tissue experiments?

Leff P, Dougall IG, Harper DH, Dainty IA.

Trends Pharmacol Sci. 1990 Feb;11(2):64-7. Review.


The interaction of methoctramine and himbacine at atrial, smooth muscle and endothelial muscarinic receptors in vitro.

Eglen RM, Montgomery WW, Dainty IA, Dubuque LK, Whiting RL.

Br J Pharmacol. 1988 Dec;95(4):1031-8.

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