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Adverse Cardiovascular Effects of Traffic Noise with a Focus on Nighttime Noise and the New WHO Noise Guidelines.

Münzel T, Kroeller-Schön S, Oelze M, Gori T, Schmidt FP, Steven S, Hahad O, Röösli M, Wunderli JM, Daiber A, Sørensen M.

Annu Rev Public Health. 2020 Jan 10. doi: 10.1146/annurev-publhealth-081519-062400. [Epub ahead of print]


Effects of clopidogrel vs. prasugrel vs. ticagrelor on endothelial function, inflammatory parameters, and platelet function in patients with acute coronary syndrome undergoing coronary artery stenting: a randomized, blinded, parallel study.

Schnorbus B, Daiber A, Jurk K, Warnke S, Koenig J, Lackner KJ, Münzel T, Gori T.

Eur Heart J. 2020 Jan 3. pii: ehz917. doi: 10.1093/eurheartj/ehz917. [Epub ahead of print]


Native, Intact Glucagon-Like Peptide-1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions.

Sternkopf M, Nagy M, Baaten CCFMJ, Kuijpers MJE, Tullemans BME, Wirth J, Theelen W, Mastenbroek TG, Lehrke M, Winnerling B, Baerts L, Marx N, De Meester I, Döring Y, Cosemans JMEM, Daiber A, Steven S, Jankowski J, Heemskerk JWM, Noels H.

Arterioscler Thromb Vasc Biol. 2020 Jan 2:ATVBAHA119313645. doi: 10.1161/ATVBAHA.119.313645. [Epub ahead of print]


The sixth sense is involved in noise-induced stress responses and vascular inflammation: evidence for heightened amygdalar activity in response to transport noise in man.

Münzel T, Steven S, Hahad O, Daiber A.

Eur Heart J. 2019 Dec 20. pii: ehz867. doi: 10.1093/eurheartj/ehz867. [Epub ahead of print] No abstract available.


Influence of mental stress and environmental toxins on circadian clocks - implications for redox regulation of the heart and cardioprotection.

Li H, Kilgallen AB, Münzel T, Wolf E, Lecour S, Schulz R, Daiber A, Van Laake LW.

Br J Pharmacol. 2019 Dec 12. doi: 10.1111/bph.14949. [Epub ahead of print] Review.


Environmental Noise-Induced Effects on Stress Hormones, Oxidative Stress, and Vascular Dysfunction: Key Factors in the Relationship between Cerebrocardiovascular and Psychological Disorders.

Hahad O, Prochaska JH, Daiber A, Muenzel T.

Oxid Med Cell Longev. 2019 Nov 11;2019:4623109. doi: 10.1155/2019/4623109. eCollection 2019. Review.


Apolipoprotein E Deficiency Causes Endothelial Dysfunction in the Mouse Retina.

Zadeh JK, Zhutdieva MB, Laspas P, Yuksel C, Musayeva A, Pfeiffer N, Brochhausen C, Oelze M, Daiber A, Xia N, Li H, Gericke A.

Oxid Med Cell Longev. 2019 Nov 12;2019:5181429. doi: 10.1155/2019/5181429. eCollection 2019.


Endothelial GLP-1 (Glucagon-Like Peptide-1) Receptor Mediates Cardiovascular Protection by Liraglutide In Mice With Experimental Arterial Hypertension.

Helmstädter J, Frenis K, Filippou K, Grill A, Dib M, Kalinovic S, Pawelke F, Kus K, Kröller-Schön S, Oelze M, Chlopicki S, Schuppan D, Wenzel P, Ruf W, Drucker DJ, Münzel T, Daiber A, Steven S.

Arterioscler Thromb Vasc Biol. 2020 Jan;40(1):145-158. doi: 10.1161/atv.0000615456.97862.30. Epub 2019 Nov 21.


Short-term e-cigarette vapour exposure causes vascular oxidative stress and dysfunction: evidence for a close connection to brain damage and a key role of the phagocytic NADPH oxidase (NOX-2).

Kuntic M, Oelze M, Steven S, Kröller-Schön S, Stamm P, Kalinovic S, Frenis K, Vujacic-Mirski K, Bayo Jimenez MT, Kvandova M, Filippou K, Al Zuabi A, Brückl V, Hahad O, Daub S, Varveri F, Gori T, Huesmann R, Hoffmann T, Schmidt FP, Keaney JF, Daiber A, Münzel T.

Eur Heart J. 2019 Nov 13. pii: ehz772. doi: 10.1093/eurheartj/ehz772. [Epub ahead of print]


Acute exposure to nocturnal train noise induces endothelial dysfunction and pro-thromboinflammatory changes of the plasma proteome in healthy subjects.

Herzog J, Schmidt FP, Hahad O, Mahmoudpour SH, Mangold AK, Garcia Andreo P, Prochaska J, Koeck T, Wild PS, Sørensen M, Daiber A, Münzel T.

Basic Res Cardiol. 2019 Oct 29;114(6):46. doi: 10.1007/s00395-019-0753-y.


Comparison of Mitochondrial Superoxide Detection Ex Vivo/In Vivo by mitoSOX HPLC Method with Classical Assays in Three Different Animal Models of Oxidative Stress.

Kalinovic S, Oelze M, Kröller-Schön S, Steven S, Vujacic-Mirski K, Kvandová M, Schmal I, Al Zuabi A, Münzel T, Daiber A.

Antioxidants (Basel). 2019 Oct 28;8(11). pii: E514. doi: 10.3390/antiox8110514.


The air pollution constituent particulate matter (PM2.5) destabilizes coronary artery plaques.

Münzel T, Daiber A.

Eur Heart J Cardiovasc Imaging. 2019 Dec 1;20(12):1365-1367. doi: 10.1093/ehjci/jez261. No abstract available.


The anti-cancer drug doxorubicin induces substantial epigenetic changes in cultured cardiomyocytes.

Hanf A, Oelze M, Manea A, Li H, Münzel T, Daiber A.

Chem Biol Interact. 2019 Nov 1;313:108834. doi: 10.1016/j.cbi.2019.108834. Epub 2019 Sep 20.


The "exposome" concept - how environmental risk factors influence cardiovascular health.

Daiber A, Lelieveld J, Steven S, Oelze M, Kröller-Schön S, Sørensen M, Münzel T.

Acta Biochim Pol. 2019 Sep 10;66(3):269-283. doi: 10.18388/abp.2019_2853.


Telmisartan Lowers Elevated Blood Pressure in Psoriatic Mice without Attenuating Vascular Dysfunction and Inflammation.

Wild J, Schüler R, Knopp T, Molitor M, Kossmann S, Münzel T, Daiber A, Waisman A, Wenzel P, Karbach SH.

Int J Mol Sci. 2019 Aug 30;20(17). pii: E4261. doi: 10.3390/ijms20174261.


The roles of gut microbiota and circadian rhythm in the cardiovascular protective effects of polyphenols.

Man AWC, Xia N, Daiber A, Li H.

Br J Pharmacol. 2019 Aug 29. doi: 10.1111/bph.14850. [Epub ahead of print] Review.


T Cell-Derived IL-17A Induces Vascular Dysfunction via Perivascular Fibrosis Formation and Dysregulation of ·NO/cGMP Signaling.

Schüler R, Efentakis P, Wild J, Lagrange J, Garlapati V, Molitor M, Kossmann S, Oelze M, Stamm P, Li H, Schäfer K, Münzel T, Daiber A, Waisman A, Wenzel P, Karbach SH.

Oxid Med Cell Longev. 2019 Jul 18;2019:6721531. doi: 10.1155/2019/6721531. eCollection 2019.


Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease.

Steven S, Frenis K, Oelze M, Kalinovic S, Kuntic M, Bayo Jimenez MT, Vujacic-Mirski K, Helmstädter J, Kröller-Schön S, Münzel T, Daiber A.

Oxid Med Cell Longev. 2019 Jun 23;2019:7092151. doi: 10.1155/2019/7092151. eCollection 2019. Review.


Reductive modification of genetically encoded 3-nitrotyrosine sites in alpha synuclein expressed in E.coli.

Gerding HR, Karreman C, Daiber A, Delp J, Hammler D, Mex M, Schildknecht S, Leist M.

Redox Biol. 2019 Sep;26:101251. doi: 10.1016/j.redox.2019.101251. Epub 2019 Jun 10.


Chronic occupational noise exposure: Effects on DNA damage, blood pressure, and serum biochemistry.

Bagheri Hosseinabadi M, Khanjani N, Münzel T, Daiber A, Yaghmorloo M.

Mutat Res. 2019 May;841:17-22. doi: 10.1016/j.mrgentox.2019.04.006. Epub 2019 Apr 26.


The Cardiovascular Effects of Noise.

Hahad O, Kröller-Schön S, Daiber A, Münzel T.

Dtsch Arztebl Int. 2019 Apr 5;116(14):245-250. doi: 10.3238/arztebl.2019.0245. Review.


Resveratrol and Vascular Function.

Li H, Xia N, Hasselwander S, Daiber A.

Int J Mol Sci. 2019 Apr 30;20(9). pii: E2155. doi: 10.3390/ijms20092155. Review.


Contribution of airborne desert dust to air quality and cardiopulmonary disease.

Münzel T, Lelieveld J, Rajagopalan S, Daiber A.

Eur Heart J. 2019 Jul 21;40(28):2377-2378. doi: 10.1093/eurheartj/ehz216. No abstract available.


Environmental noise induces the release of stress hormones and inflammatory signaling molecules leading to oxidative stress and vascular dysfunction-Signatures of the internal exposome.

Daiber A, Kröller-Schön S, Frenis K, Oelze M, Kalinovic S, Vujacic-Mirski K, Kuntic M, Bayo Jimenez MT, Helmstädter J, Steven S, Korac B, Münzel T.

Biofactors. 2019 Jul;45(4):495-506. doi: 10.1002/biof.1506. Epub 2019 Apr 2. Review.


Cardiovascular disease burden from ambient air pollution in Europe reassessed using novel hazard ratio functions.

Lelieveld J, Klingmüller K, Pozzer A, Pöschl U, Fnais M, Daiber A, Münzel T.

Eur Heart J. 2019 May 21;40(20):1590-1596. doi: 10.1093/eurheartj/ehz135.


The Endothelin Receptor Antagonist Macitentan Improves Isosorbide-5-Mononitrate (ISMN) and Isosorbide Dinitrate (ISDN) Induced Endothelial Dysfunction, Oxidative Stress, and Vascular Inflammation.

Steven S, Oelze M, Hausding M, Roohani S, Kashani F, Kröller-Schön S, Helmstädter J, Jansen T, Baum C, Iglarz M, Schulz E, Münzel T, Daiber A.

Oxid Med Cell Longev. 2018 Dec 27;2018:7845629. doi: 10.1155/2018/7845629. eCollection 2018.


Oxidative Stress in Cardiac Tissue of Patients Undergoing Coronary Artery Bypass Graft Surgery: The Effects of Overweight and Obesity.

Gramlich Y, Daiber A, Buschmann K, Oelze M, Vahl CF, Münzel T, Hink U.

Oxid Med Cell Longev. 2018 Dec 17;2018:6598326. doi: 10.1155/2018/6598326. eCollection 2018.


Endothelial α1AMPK modulates angiotensin II-mediated vascular inflammation and dysfunction.

Kröller-Schön S, Jansen T, Tran TLP, Kvandová M, Kalinovic S, Oelze M, Keaney JF Jr, Foretz M, Viollet B, Daiber A, Kossmann S, Lagrange J, Frenis K, Wenzel P, Münzel T, Schulz E.

Basic Res Cardiol. 2019 Jan 14;114(2):8. doi: 10.1007/s00395-019-0717-2.


New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease.

Daiber A, Xia N, Steven S, Oelze M, Hanf A, Kröller-Schön S, Münzel T, Li H.

Int J Mol Sci. 2019 Jan 7;20(1). pii: E187. doi: 10.3390/ijms20010187. Review.


Antihypertensive Decapeptide From Cyanobacterium Spirulina platensis.

Münzel T, Daiber A.

Hypertension. 2019 Feb;73(2):291-293. doi: 10.1161/HYPERTENSIONAHA.118.11893. No abstract available.


Antagonization of IL-17A Attenuates Skin Inflammation and Vascular Dysfunction in Mouse Models of Psoriasis.

Schüler R, Brand A, Klebow S, Wild J, Veras FP, Ullmann E, Roohani S, Kolbinger F, Kossmann S, Wohn C, Daiber A, Münzel T, Wenzel P, Waisman A, Clausen BE, Karbach S.

J Invest Dermatol. 2019 Mar;139(3):638-647. doi: 10.1016/j.jid.2018.09.021. Epub 2018 Oct 24.


Double hazard of smoking and alcohol on vascular function in adolescents.

Münzel T, Hahad O, Daiber A.

Eur Heart J. 2019 Jan 21;40(4):354-356. doi: 10.1093/eurheartj/ehy430. No abstract available.


Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: a novel mechanism for an old drug.

Bibli SI, Papapetropoulos A, Iliodromitis EK, Daiber A, Randriamboavonjy V, Steven S, Brouckaert P, Chatzianastasiou A, Kypreos KE, Hausenloy DJ, Fleming I, Andreadou I.

Cardiovasc Res. 2019 Mar 1;115(3):625-636. doi: 10.1093/cvr/cvy222.


Effects of gaseous and solid constituents of air pollution on endothelial function.

Münzel T, Gori T, Al-Kindi S, Deanfield J, Lelieveld J, Daiber A, Rajagopalan S.

Eur Heart J. 2018 Oct 7;39(38):3543-3550. doi: 10.1093/eurheartj/ehy481. Review.


Stimulatory TSH-Receptor Antibodies and Oxidative Stress in Graves Disease.

Diana T, Daiber A, Oelze M, Neumann S, Olivo PD, Kanitz M, Stamm P, Kahaly GJ.

J Clin Endocrinol Metab. 2018 Oct 1;103(10):3668-3677. doi: 10.1210/jc.2018-00509.


α1AMPK deletion in myelomonocytic cells induces a pro-inflammatory phenotype and enhances angiotensin II-induced vascular dysfunction.

Jansen T, Kröller-Schön S, Schönfelder T, Foretz M, Viollet B, Daiber A, Oelze M, Brandt M, Steven S, Kvandová M, Kalinovic S, Lagrange J, Keaney JF Jr, Münzel T, Wenzel P, Schulz E.

Cardiovasc Res. 2018 Dec 1;114(14):1883-1893. doi: 10.1093/cvr/cvy172.


Comparison of Pulmonary and Systemic NO- and PGI2-Dependent Endothelial Function in Diabetic Mice.

Fedorowicz A, Buczek E, Mateuszuk Ł, Czarnowska E, Sitek B, Jasztal A, Chmura-Skirlińska A, Dib M, Steven S, Daiber A, Chlopicki S.

Oxid Med Cell Longev. 2018 Jun 4;2018:4036709. doi: 10.1155/2018/4036709. eCollection 2018.


Crucial role for Nox2 and sleep deprivation in aircraft noise-induced vascular and cerebral oxidative stress, inflammation, and gene regulation.

Kröller-Schön S, Daiber A, Steven S, Oelze M, Frenis K, Kalinovic S, Heimann A, Schmidt FP, Pinto A, Kvandova M, Vujacic-Mirski K, Filippou K, Dudek M, Bosmann M, Klein M, Bopp T, Hahad O, Wild PS, Frauenknecht K, Methner A, Schmidt ER, Rapp S, Mollnau H, Münzel T.

Eur Heart J. 2018 Oct 7;39(38):3528-3539. doi: 10.1093/eurheartj/ehy333.


Role of endothelial and macrophage tetrahydrobiopterin in development and progression of atherosclerosis: BH4 puzzle solved?

Münzel T, Daiber A.

Cardiovasc Res. 2018 Aug 1;114(10):1310-1312. doi: 10.1093/cvr/cvy118. No abstract available.


Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach.

Cuadrado A, Manda G, Hassan A, Alcaraz MJ, Barbas C, Daiber A, Ghezzi P, León R, López MG, Oliva B, Pajares M, Rojo AI, Robledinos-Antón N, Valverde AM, Guney E, Schmidt HHHW.

Pharmacol Rev. 2018 Apr;70(2):348-383. doi: 10.1124/pr.117.014753. Review.


Modulation of Vascular Function by AMPK: Assessment of NO Bioavailability and Surrogates of Oxidative Stress.

Kröller-Schön S, Daiber A, Schulz E.

Methods Mol Biol. 2018;1732:495-506. doi: 10.1007/978-1-4939-7598-3_31.


The potential of aldehyde dehydrogenase 2 as a therapeutic target in cardiovascular disease.

Münzel T, Daiber A.

Expert Opin Ther Targets. 2018 Mar;22(3):217-231. doi: 10.1080/14728222.2018.1439922. Epub 2018 Feb 16. Review.


Environmental Noise and the Cardiovascular System.

Münzel T, Schmidt FP, Steven S, Herzog J, Daiber A, Sørensen M.

J Am Coll Cardiol. 2018 Feb 13;71(6):688-697. doi: 10.1016/j.jacc.2017.12.015. Review.


The Adverse Effects of Environmental Noise Exposure on Oxidative Stress and Cardiovascular Risk.

Münzel T, Sørensen M, Schmidt F, Schmidt E, Steven S, Kröller-Schön S, Daiber A.

Antioxid Redox Signal. 2018 Mar 20;28(9):873-908. doi: 10.1089/ars.2017.7118. Review.


Environmental Stressors and Their Impact on Health and Disease with Focus on Oxidative Stress.

Münzel T, Daiber A.

Antioxid Redox Signal. 2018 Mar 20;28(9):735-740. doi: 10.1089/ars.2017.7488. Epub 2018 Feb 2. Review.


Inorganic nitrite and nitrate in cardiovascular therapy: A better alternative to organic nitrates as nitric oxide donors?

Münzel T, Daiber A.

Vascul Pharmacol. 2018 Mar;102:1-10. doi: 10.1016/j.vph.2017.11.003. Epub 2017 Nov 22. Review.


Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

Egea J, Fabregat I, Frapart YM, Ghezzi P, Görlach A, Kietzmann T, Kubaichuk K, Knaus UG, Lopez MG, Olaso-Gonzalez G, Petry A, Schulz R, Vina J, Winyard P, Abbas K, Ademowo OS, Afonso CB, Andreadou I, Antelmann H, Antunes F, Aslan M, Bachschmid MM, Barbosa RM, Belousov V, Berndt C, Bernlohr D, Bertrán E, Bindoli A, Bottari SP, Brito PM, Carrara G, Casas AI, Chatzi A, Chondrogianni N, Conrad M, Cooke MS, Costa JG, Cuadrado A, My-Chan Dang P, De Smet B, Debelec-Butuner B, Dias IHK, Dunn JD, Edson AJ, El Assar M, El-Benna J, Ferdinandy P, Fernandes AS, Fladmark KE, Förstermann U, Giniatullin R, Giricz Z, Görbe A, Griffiths H, Hampl V, Hanf A, Herget J, Hernansanz-Agustín P, Hillion M, Huang J, Ilikay S, Jansen-Dürr P, Jaquet V, Joles JA, Kalyanaraman B, Kaminskyy D, Karbaschi M, Kleanthous M, Klotz LO, Korac B, Korkmaz KS, Koziel R, Kračun D, Krause KH, Křen V, Krieg T, Laranjinha J, Lazou A, Li H, Martínez-Ruiz A, Matsui R, McBean GJ, Meredith SP, Messens J, Miguel V, Mikhed Y, Milisav I, Milković L, Miranda-Vizuete A, Mojović M, Monsalve M, Mouthuy PA, Mulvey J, Münzel T, Muzykantov V, Nguyen ITN, Oelze M, Oliveira NG, Palmeira CM, Papaevgeniou N, Pavićević A, Pedre B, Peyrot F, Phylactides M, Pircalabioru GG, Pitt AR, Poulsen HE, Prieto I, Rigobello MP, Robledinos-Antón N, Rodríguez-Mañas L, Rolo AP, Rousset F, Ruskovska T, Saraiva N, Sasson S, Schröder K, Semen K, Seredenina T, Shakirzyanova A, Smith GL, Soldati T, Sousa BC, Spickett CM, Stancic A, Stasia MJ, Steinbrenner H, Stepanić V, Steven S, Tokatlidis K, Tuncay E, Turan B, Ursini F, Vacek J, Vajnerova O, Valentová K, Van Breusegem F, Varisli L, Veal EA, Yalçın AS, Yelisyeyeva O, Žarković N, Zatloukalová M, Zielonka J, Touyz RM, Papapetropoulos A, Grune T, Lamas S, Schmidt HHHW, Di Lisa F, Daiber A.

Redox Biol. 2018 Apr;14:694-696. doi: 10.1016/j.redox.2017.10.001. Epub 2017 Oct 26. No abstract available.


Health Benefits of Fasting and Caloric Restriction.

Golbidi S, Daiber A, Korac B, Li H, Essop MF, Laher I.

Curr Diab Rep. 2017 Oct 23;17(12):123. doi: 10.1007/s11892-017-0951-7. Review.


Time Response of Oxidative/Nitrosative Stress and Inflammation in LPS-Induced Endotoxaemia-A Comparative Study of Mice and Rats.

Steven S, Dib M, Roohani S, Kashani F, Münzel T, Daiber A.

Int J Mol Sci. 2017 Oct 18;18(10). pii: E2176. doi: 10.3390/ijms18102176.


CD40L controls obesity-associated vascular inflammation, oxidative stress, and endothelial dysfunction in high fat diet-treated and db/db mice.

Steven S, Dib M, Hausding M, Kashani F, Oelze M, Kröller-Schön S, Hanf A, Daub S, Roohani S, Gramlich Y, Lutgens E, Schulz E, Becker C, Lackner KJ, Kleinert H, Knosalla C, Niesler B, Wild PS, Münzel T, Daiber A.

Cardiovasc Res. 2018 Feb 1;114(2):312-323. doi: 10.1093/cvr/cvx197.


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