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Items: 1 to 50 of 122

1.

Evaluation of the Genetic Association Between Adult Obesity and Neuropsychiatric Disease.

Stahel P, Nahmias A, Sud SK, Lee SJ, Pucci A, Yousseif A, Yosseff A, Jackson T, Urbach DR, Okrainec A, Allard JP, Sockalingam S, Yao J, Barua M, Jiao H, Magi R, Bassett AS, Paterson AD, Dahlman I, Batterham RL, Dash S.

Diabetes. 2019 Sep 10. pii: db181254. doi: 10.2337/db18-1254. [Epub ahead of print]

PMID:
31506345
2.

Prospective analyses of white adipose tissue gene expression in relation to long-term body weight changes.

Kwok KHM, Rydén M, Andersson DP, Beauchef G, Guere C, Vie K, Bergman O, Lundbäck V, Arner P, Dahlman I.

Int J Obes (Lond). 2019 Jun 4. doi: 10.1038/s41366-019-0385-1. [Epub ahead of print]

PMID:
31164724
3.

MicroRNA-196a links human body fat distribution to adipose tissue extracellular matrix composition.

Hilton C, Neville MJ, Wittemans LBL, Todorcevic M, Pinnick KE, Pulit SL, Luan J, Kulyté A, Dahlman I, Wareham NJ, Lotta LA, Arner P, Lindgren CM, Langenberg C, Karpe F.

EBioMedicine. 2019 Jun;44:467-475. doi: 10.1016/j.ebiom.2019.05.047. Epub 2019 May 28.

4.

Epigenetic regulation of diabetogenic adipose morphology.

Kerr AG, Sinha I, Dadvar S, Arner P, Dahlman I.

Mol Metab. 2019 Jul;25:159-167. doi: 10.1016/j.molmet.2019.04.009. Epub 2019 Apr 17.

5.

Healthy Nordic Diet Modulates the Expression of Genes Related to Mitochondrial Function and Immune Response in Peripheral Blood Mononuclear Cells from Subjects with Metabolic Syndrome-A SYSDIET Sub-Study.

Myhrstad MCW, de Mello VD, Dahlman I, Kolehmainen M, Paananen J, Rundblad A, Carlberg C, Olstad OK, Pihlajamäki J, Holven KB, Hermansen K, Dragsted LO, Gunnarsdottir I, Cloetens L, Storm MU, Åkesson B, Rosqvist F, Hukkanen J, Herzig KH, Risérus U, Thorsdottir I, Poutanen KS, Savolainen MJ, Schwab U, Arner P, Uusitupa M, Ulven SM.

Mol Nutr Food Res. 2019 Apr 9:e1801405. doi: 10.1002/mnfr.201801405. [Epub ahead of print]

PMID:
30964598
6.

Apolipoprotein M: a novel adipokine decreasing with obesity and upregulated by calorie restriction.

Sramkova V, Berend S, Siklova M, Caspar-Bauguil S, Carayol J, Bonnel S, Marques M, Decaunes P, Kolditz CI, Dahlman I, Arner P, Stich V, Saris WHM, Astrup A, Valsesia A, Rossmeislova L, Langin D, Viguerie N.

Am J Clin Nutr. 2019 Jun 1;109(6):1499-1510. doi: 10.1093/ajcn/nqy331.

PMID:
30869115
7.

Insulin action is severely impaired in adipocytes of apparently healthy overweight and obese subjects.

Rydén M, Petrus P, Andersson DP, Medina-Gómez G, Escasany E, Corrales Cordón P, Dahlman I, Kulyté A, Arner P.

J Intern Med. 2019 May;285(5):578-588. doi: 10.1111/joim.12887. Epub 2019 Mar 14.

PMID:
30758089
8.

The effect of different sources of fish and camelina sativa oil on immune cell and adipose tissue mRNA expression in subjects with abnormal fasting glucose metabolism: a randomized controlled trial.

de Mello VD, Dahlman I, Lankinen M, Kurl S, Pitkänen L, Laaksonen DE, Schwab US, Erkkilä AT.

Nutr Diabetes. 2019 Jan 9;9(1):1. doi: 10.1038/s41387-018-0069-2.

9.

Improved metabolism and body composition beyond normal levels following gastric bypass surgery: a longitudinal study.

Andersson DP, Dahlman I, Eriksson Hogling D, Bäckdahl J, Toft E, Qvisth V, Näslund E, Thorell A, Rydén M, Arner P.

J Intern Med. 2019 Jan;285(1):92-101. doi: 10.1111/joim.12824. Epub 2018 Sep 25.

PMID:
30141528
10.

Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition.

Small KS, Todorčević M, Civelek M, El-Sayed Moustafa JS, Wang X, Simon MM, Fernandez-Tajes J, Mahajan A, Horikoshi M, Hugill A, Glastonbury CA, Quaye L, Neville MJ, Sethi S, Yon M, Pan C, Che N, Vinuela A, Tsai PC, Nag A, Buil A, Thorleifsson G, Raghavan A, Ding Q, Morris AP, Bell JT, Thorsteinsdottir U, Stefansson K, Laakso M, Dahlman I, Arner P, Gloyn AL, Musunuru K, Lusis AJ, Cox RD, Karpe F, McCarthy MI.

Nat Genet. 2018 Sep;50(9):1342. doi: 10.1038/s41588-018-0180-2.

PMID:
30087441
11.

Weight Gain and Impaired Glucose Metabolism in Women Are Predicted by Inefficient Subcutaneous Fat Cell Lipolysis.

Arner P, Andersson DP, Bäckdahl J, Dahlman I, Rydén M.

Cell Metab. 2018 Jul 3;28(1):45-54.e3. doi: 10.1016/j.cmet.2018.05.004. Epub 2018 May 31.

12.

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition.

Small KS, Todorčević M, Civelek M, El-Sayed Moustafa JS, Wang X, Simon MM, Fernandez-Tajes J, Mahajan A, Horikoshi M, Hugill A, Glastonbury CA, Quaye L, Neville MJ, Sethi S, Yon M, Pan C, Che N, Viñuela A, Tsai PC, Nag A, Buil A, Thorleifsson G, Raghavan A, Ding Q, Morris AP, Bell JT, Thorsteinsdottir U, Stefansson K, Laakso M, Dahlman I, Arner P, Gloyn AL, Musunuru K, Lusis AJ, Cox RD, Karpe F, McCarthy MI.

Nat Genet. 2018 Apr;50(4):572-580. doi: 10.1038/s41588-018-0088-x. Epub 2018 Apr 9. Erratum in: Nat Genet. 2018 Sep;50(9):1342.

13.

Long Non-Coding RNAs Associated with Metabolic Traits in Human White Adipose Tissue.

Gao H, Kerr A, Jiao H, Hon CC, Rydén M, Dahlman I, Arner P.

EBioMedicine. 2018 Apr;30:248-260. doi: 10.1016/j.ebiom.2018.03.010. Epub 2018 Mar 15.

14.

FAM13A and POM121C are candidate genes for fasting insulin: functional follow-up analysis of a genome-wide association study.

Lundbäck V, Kulyte A, Strawbridge RJ, Ryden M, Arner P, Marcus C, Dahlman I.

Diabetologia. 2018 May;61(5):1112-1123. doi: 10.1007/s00125-018-4572-8. Epub 2018 Feb 27.

15.

Screening of potential adipokines identifies S100A4 as a marker of pernicious adipose tissue and insulin resistance.

Arner P, Petrus P, Esteve D, Boulomié A, Näslund E, Thorell A, Gao H, Dahlman I, Rydén M.

Int J Obes (Lond). 2018 Dec;42(12):2047-2056. doi: 10.1038/s41366-018-0018-0. Epub 2018 Jan 30.

PMID:
29453465
16.

Family history of diabetes is associated with enhanced adipose lipolysis: Evidence for the implication of epigenetic factors.

Dahlman I, Ryden M, Arner P.

Diabetes Metab. 2018 Mar;44(2):155-159. doi: 10.1016/j.diabet.2017.10.010. Epub 2017 Nov 11.

PMID:
29153750
17.

Adipocyte Expression of SLC19A1 Links DNA Hypermethylation to Adipose Tissue Inflammation and Insulin Resistance.

Petrus P, Bialesova L, Checa A, Kerr A, Naz S, Bäckdahl J, Gracia A, Toft S, Dahlman-Wright K, Hedén P, Dahlman I, Wheelock CE, Arner P, Mejhert N, Gao H, Rydén M.

J Clin Endocrinol Metab. 2018 Feb 1;103(2):710-721. doi: 10.1210/jc.2017-01382.

PMID:
29121255
18.

Epigenetic Regulation of PLIN 1 in Obese Women and its Relation to Lipolysis.

Bialesova L, Kulyté A, Petrus P, Sinha I, Laurencikiene J, Zhao C, Wright KD, Arner P, Dahlman I.

Sci Rep. 2017 Aug 31;7(1):10152. doi: 10.1038/s41598-017-09232-y.

19.

Thyroid-Stimulating Hormone, Degree of Obesity, and Metabolic Risk Markers in a Cohort of Swedish Children with Obesity.

Lundbäck V, Ekbom K, Hagman E, Dahlman I, Marcus C.

Horm Res Paediatr. 2017;88(2):140-146. doi: 10.1159/000475993. Epub 2017 Jun 14.

PMID:
28614818
20.

Global transcriptome profiling identifies KLF15 and SLC25A10 as modifiers of adipocytes insulin sensitivity in obese women.

Kulyté A, Ehrlund A, Arner P, Dahlman I.

PLoS One. 2017 Jun 1;12(6):e0178485. doi: 10.1371/journal.pone.0178485. eCollection 2017.

21.

Depot-specific differences in fatty acid composition and distinct associations with lipogenic gene expression in abdominal adipose tissue of obese women.

Petrus P, Edholm D, Rosqvist F, Dahlman I, Sundbom M, Arner P, Rydén M, Risérus U.

Int J Obes (Lond). 2017 Aug;41(8):1295-1298. doi: 10.1038/ijo.2017.106. Epub 2017 May 3.

22.

Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation.

Lee H, Qian K, von Toerne C, Hoerburger L, Claussnitzer M, Hoffmann C, Glunk V, Wahl S, Breier M, Eck F, Jafari L, Molnos S, Grallert H, Dahlman I, Arner P, Brunner C, Hauner H, Hauck SM, Laumen H.

Nucleic Acids Res. 2017 Apr 7;45(6):3266-3279. doi: 10.1093/nar/gkx105.

23.

Impact of polyunsaturated and saturated fat overfeeding on the DNA-methylation pattern in human adipose tissue: a randomized controlled trial.

Perfilyev A, Dahlman I, Gillberg L, Rosqvist F, Iggman D, Volkov P, Nilsson E, Risérus U, Ling C.

Am J Clin Nutr. 2017 Apr;105(4):991-1000. doi: 10.3945/ajcn.116.143164. Epub 2017 Mar 8. Erratum in: Am J Clin Nutr. 2017 Jul;106(1):325.

PMID:
28275132
24.

Comprehensive functional screening of miRNAs involved in fat cell insulin sensitivity among women.

Dahlman I, Belarbi Y, Laurencikiene J, Pettersson AM, Arner P, Kulyté A.

Am J Physiol Endocrinol Metab. 2017 Jun 1;312(6):E482-E494. doi: 10.1152/ajpendo.00251.2016. Epub 2017 Mar 7.

25.

Adipose and Circulating CCL18 Levels Associate With Metabolic Risk Factors in Women.

Eriksson Hogling D, Petrus P, Gao H, Bäckdahl J, Dahlman I, Laurencikiene J, Acosta J, Ehrlund A, Näslund E, Kulyte A, Mejhert N, Andersson DP, Arner P, Rydén M.

J Clin Endocrinol Metab. 2016 Nov;101(11):4021-4029. Epub 2016 Jul 26.

PMID:
27459538
26.

Erratum to: The epigenetic signature of systemic insulin resistance in obese women.

Arner P, Sahlqvist AS, Sinha I, Xu H, Yao X, Waterworth D, Rajpal D, Loomis AK, Freudenberg JM, Johnson T, Thorell A, Näslund E, Ryden M, Dahlman I.

Diabetologia. 2016 Dec;59(12):2728. No abstract available.

PMID:
27695898
27.

An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice.

Rohm M, Schäfer M, Laurent V, Üstünel BE, Niopek K, Algire C, Hautzinger O, Sijmonsma TP, Zota A, Medrikova D, Pellegata NS, Ryden M, Kulyte A, Dahlman I, Arner P, Petrovic N, Cannon B, Amri EZ, Kemp BE, Steinberg GR, Janovska P, Kopecky J, Wolfrum C, Blüher M, Berriel Diaz M, Herzig S.

Nat Med. 2016 Oct;22(10):1120-1130. doi: 10.1038/nm.4171. Epub 2016 Aug 29.

PMID:
27571348
28.

The Adipose Transcriptional Response to Insulin Is Determined by Obesity, Not Insulin Sensitivity.

Rydén M, Hrydziuszko O, Mileti E, Raman A, Bornholdt J, Boyd M, Toft E, Qvist V, Näslund E, Thorell A, Andersson DP, Dahlman I, Gao H, Sandelin A, Daub CO, Arner P.

Cell Rep. 2016 Aug 30;16(9):2317-26. doi: 10.1016/j.celrep.2016.07.070. Epub 2016 Aug 18.

29.

The epigenetic signature of systemic insulin resistance in obese women.

Arner P, Sahlqvist AS, Sinha I, Xu H, Yao X, Waterworth D, Rajpal D, Loomis AK, Freudenberg JM, Johnson T, Thorell A, Näslund E, Ryden M, Dahlman I.

Diabetologia. 2016 Nov;59(11):2393-2405. doi: 10.1007/s00125-016-4074-5. Epub 2016 Aug 18. Erratum in: Diabetologia. 2016 Sep 30;:.

30.

Datasets of genes coexpressed with FBN1 in mouse adipose tissue and during human adipogenesis.

Davis MR, Arner E, Duffy CR, De Sousa PA, Dahlman I, Arner P, Summers KM.

Data Brief. 2016 Jul 5;8:851-7. doi: 10.1016/j.dib.2016.06.055. eCollection 2016 Sep.

31.

Effects of a healthy Nordic diet on gene expression changes in peripheral blood mononuclear cells in response to an oral glucose tolerance test in subjects with metabolic syndrome: a SYSDIET sub-study.

Leder L, Kolehmainen M, Narverud I, Dahlman I, Myhrstad MC, de Mello VD, Paananen J, Carlberg C, Schwab U, Herzig KH, Cloetens L, Storm MU, Hukkanen J, Savolainen MJ, Rosqvist F, Hermansen K, Dragsted LO, Gunnarsdottir I, Thorsdottir I, Risérus U, Åkesson B, Thoresen M, Arner P, Poutanen KS, Uusitupa M, Holven KB, Ulven SM.

Genes Nutr. 2016 Mar 17;11:3. doi: 10.1186/s12263-016-0521-4. eCollection 2016.

32.

Whole-Exome Sequencing Suggests LAMB3 as a Susceptibility Gene for Morbid Obesity.

Jiao H, Kulyté A, Näslund E, Thorell A, Gerdhem P, Kere J, Arner P, Dahlman I.

Diabetes. 2016 Oct;65(10):2980-9. doi: 10.2337/db16-0522. Epub 2016 Jul 18.

33.

Expression of FBN1 during adipogenesis: Relevance to the lipodystrophy phenotype in Marfan syndrome and related conditions.

Davis MR, Arner E, Duffy CR, De Sousa PA, Dahlman I, Arner P, Summers KM.

Mol Genet Metab. 2016 Sep;119(1-2):174-85. doi: 10.1016/j.ymgme.2016.06.009. Epub 2016 Jun 23.

34.

Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis.

Strawbridge RJ, Laumen H, Hamsten A, Breier M, Grallert H, Hauner H, Arner P, Dahlman I.

PLoS One. 2016 Apr 22;11(4):e0153990. doi: 10.1371/journal.pone.0153990. eCollection 2016.

35.

Numerous Genes in Loci Associated With Body Fat Distribution Are Linked to Adipose Function.

Dahlman I, Rydén M, Brodin D, Grallert H, Strawbridge RJ, Arner P.

Diabetes. 2016 Feb;65(2):433-7. doi: 10.2337/db15-0828.

36.

Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.

Gillberg L, Perfilyev A, Brøns C, Thomasen M, Grunnet LG, Volkov P, Rosqvist F, Iggman D, Dahlman I, Risérus U, Rönn T, Nilsson E, Vaag A, Ling C.

Diabetologia. 2016 Apr;59(4):799-812. doi: 10.1007/s00125-015-3852-9. Epub 2016 Jan 11.

PMID:
26750116
37.

The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women.

Arner P, Sinha I, Thorell A, Rydén M, Dahlman-Wright K, Dahlman I.

Clin Epigenetics. 2015 Sep 8;7:93. doi: 10.1186/s13148-015-0126-9. eCollection 2015.

38.

Mesoderm-specific transcript (MEST) is a negative regulator of human adipocyte differentiation.

Karbiener M, Glantschnig C, Pisani DF, Laurencikiene J, Dahlman I, Herzig S, Amri EZ, Scheideler M.

Int J Obes (Lond). 2015 Dec;39(12):1733-41. doi: 10.1038/ijo.2015.121. Epub 2015 Jun 29.

39.

MicroRNA-193b Controls Adiponectin Production in Human White Adipose Tissue.

Belarbi Y, Mejhert N, Lorente-Cebrián S, Dahlman I, Arner P, Rydén M, Kulyté A.

J Clin Endocrinol Metab. 2015 Aug;100(8):E1084-8. doi: 10.1210/jc.2015-1530. Epub 2015 May 28.

PMID:
26020766
40.

Potential role of milk fat globule membrane in modulating plasma lipoproteins, gene expression, and cholesterol metabolism in humans: a randomized study.

Rosqvist F, Smedman A, Lindmark-Månsson H, Paulsson M, Petrus P, Straniero S, Rudling M, Dahlman I, Risérus U.

Am J Clin Nutr. 2015 Jul;102(1):20-30. doi: 10.3945/ajcn.115.107045. Epub 2015 May 27.

PMID:
26016870
41.

Candidate gene analysis and exome sequencing confirm LBX1 as a susceptibility gene for idiopathic scoliosis.

Grauers A, Wang J, Einarsdottir E, Simony A, Danielsson A, Åkesson K, Ohlin A, Halldin K, Grabowski P, Tenne M, Laivuori H, Dahlman I, Andersen M, Christensen SB, Karlsson MK, Jiao H, Kere J, Gerdhem P.

Spine J. 2015 Oct 1;15(10):2239-46. doi: 10.1016/j.spinee.2015.05.013. Epub 2015 May 15.

PMID:
25987191
42.

Saturated fatty acids in human visceral adipose tissue are associated with increased 11- β-hydroxysteroid-dehydrogenase type 1 expression.

Petrus P, Rosqvist F, Edholm D, Mejhert N, Arner P, Dahlman I, Rydén M, Sundbom M, Risérus U.

Lipids Health Dis. 2015 May 2;14:42. doi: 10.1186/s12944-015-0042-1.

43.

Circulating carnosine dipeptidase 1 associates with weight loss and poor prognosis in gastrointestinal cancer.

Arner P, Henjes F, Schwenk JM, Darmanis S, Dahlman I, Iresjö BM, Naredi P, Agustsson T, Lundholm K, Nilsson P, Rydén M.

PLoS One. 2015 Apr 21;10(4):e0123566. doi: 10.1371/journal.pone.0123566. eCollection 2015.

44.

Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue.

Minchin JE, Dahlman I, Harvey CJ, Mejhert N, Singh MK, Epstein JA, Arner P, Torres-Vázquez J, Rawls JF.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4363-8. doi: 10.1073/pnas.1416412112. Epub 2015 Mar 23.

45.

The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.

Dahlman I, Sinha I, Gao H, Brodin D, Thorell A, Rydén M, Andersson DP, Henriksson J, Perfilyev A, Ling C, Dahlman-Wright K, Arner P.

Int J Obes (Lond). 2015 Jun;39(6):910-9. doi: 10.1038/ijo.2015.31. Epub 2015 Mar 18.

PMID:
25783037
46.

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome.

Kolehmainen M, Ulven SM, Paananen J, de Mello V, Schwab U, Carlberg C, Myhrstad M, Pihlajamäki J, Dungner E, Sjölin E, Gunnarsdottir I, Cloetens L, Landin-Olsson M, Akesson B, Rosqvist F, Hukkanen J, Herzig KH, Dragsted LO, Savolainen MJ, Brader L, Hermansen K, Risérus U, Thorsdottir I, Poutanen KS, Uusitupa M, Arner P, Dahlman I.

Am J Clin Nutr. 2015 Jan;101(1):228-39. doi: 10.3945/ajcn.114.092783. Epub 2014 Nov 19.

PMID:
25527767
47.

Exome sequencing followed by genotyping suggests SYPL2 as a susceptibility gene for morbid obesity.

Jiao H, Arner P, Gerdhem P, Strawbridge RJ, Näslund E, Thorell A, Hamsten A, Kere J, Dahlman I.

Eur J Hum Genet. 2015 Sep;23(9):1216-22. doi: 10.1038/ejhg.2014.255. Epub 2014 Nov 19.

48.

Early B cell factor 1 regulates adipocyte morphology and lipolysis in white adipose tissue.

Gao H, Mejhert N, Fretz JA, Arner E, Lorente-Cebrián S, Ehrlund A, Dahlman-Wright K, Gong X, Strömblad S, Douagi I, Laurencikiene J, Dahlman I, Daub CO, Rydén M, Horowitz MC, Arner P.

Cell Metab. 2014 Jun 3;19(6):981-92. doi: 10.1016/j.cmet.2014.03.032. Epub 2014 May 22.

49.

Changes in subcutaneous fat cell volume and insulin sensitivity after weight loss.

Andersson DP, Eriksson Hogling D, Thorell A, Toft E, Qvisth V, Näslund E, Thörne A, Wirén M, Löfgren P, Hoffstedt J, Dahlman I, Mejhert N, Rydén M, Arner E, Arner P.

Diabetes Care. 2014 Jul;37(7):1831-6. doi: 10.2337/dc13-2395. Epub 2014 Apr 23.

PMID:
24760260
50.

Overfeeding polyunsaturated and saturated fat causes distinct effects on liver and visceral fat accumulation in humans.

Rosqvist F, Iggman D, Kullberg J, Cedernaes J, Johansson HE, Larsson A, Johansson L, Ahlström H, Arner P, Dahlman I, Risérus U.

Diabetes. 2014 Jul;63(7):2356-68. doi: 10.2337/db13-1622. Epub 2014 Feb 18.

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