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Items: 1 to 50 of 297

1.

Interdependent allosteric free fatty acid receptor 2 modulators synergistically induce functional selective activation and desensitization in neutrophils.

Lind S, Holdfeldt A, Mårtensson J, Sundqvist M, Kenakin TP, Björkman L, Forsman H, Dahlgren C.

Biochim Biophys Acta Mol Cell Res. 2020 Jun;1867(6):118689. doi: 10.1016/j.bbamcr.2020.118689. Epub 2020 Feb 21.

PMID:
32092308
2.

Measurement of Respiratory Burst Products, Released or Retained, During Activation of Professional Phagocytes.

Dahlgren C, Björnsdottir H, Sundqvist M, Christenson K, Bylund J.

Methods Mol Biol. 2020;2087:301-324. doi: 10.1007/978-1-0716-0154-9_22.

PMID:
31729000
3.

Staphylococcus aureus-Derived PSMα Peptides Activate Neutrophil FPR2 but Lack the Ability to Mediate β-Arrestin Recruitment and Chemotaxis.

Sundqvist M, Christenson K, Gabl M, Holdfeldt A, Jennbacken K, Møller TC, Dahlgren C, Forsman H.

J Immunol. 2019 Dec 15;203(12):3349-3360. doi: 10.4049/jimmunol.1900871. Epub 2019 Nov 6.

PMID:
31694908
4.

DPI Selectively Inhibits Intracellular NADPH Oxidase Activity in Human Neutrophils.

Buck A, Sanchez Klose FP, Venkatakrishnan V, Khamzeh A, Dahlgren C, Christenson K, Bylund J.

Immunohorizons. 2019 Oct 18;3(10):488-497. doi: 10.4049/immunohorizons.1900062.

PMID:
31628159
5.

Executive Function, Eating Behavior, and Preoperative Weight Loss in Bariatric Surgery Candidates: An Observational Study.

Walø-Syversen G, Kvalem IL, Kristinsson J, Eribe IL, Rø Ø, Dahlgren CL.

Obes Facts. 2019;12(5):489-501. doi: 10.1159/000502118. Epub 2019 Sep 10.

6.

Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE mutations.

Liu Q, Sundqvist M, Li W, Holdfeldt A, Zhang L, Björkman L, Bylund J, Dahlgren C, Wang C, Zhao X, Forsman H.

BMC Pediatr. 2019 Jun 8;19(1):189. doi: 10.1186/s12887-019-1556-x.

7.

Intracellular Neutrophil Oxidants: From Laboratory Curiosity to Clinical Reality.

Dahlgren C, Karlsson A, Bylund J.

J Immunol. 2019 Jun 1;202(11):3127-3134. doi: 10.4049/jimmunol.1900235. Review.

PMID:
31109945
8.

Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949.

Lind S, Sundqvist M, Holmdahl R, Dahlgren C, Forsman H, Olofsson P.

Biochem Pharmacol. 2019 Aug;166:163-173. doi: 10.1016/j.bcp.2019.04.030. Epub 2019 May 11.

PMID:
31085160
9.

Unhealthy eating and weight dissatisfaction in adolescents who never, occasionally, or regularly use smokeless tobacco (Swedish snus).

Reas DL, Wisting L, Stedal K, Dahlgren CL.

Int J Eat Disord. 2019 Jul;52(7):846-854. doi: 10.1002/eat.23085. Epub 2019 Apr 29.

PMID:
31032987
10.

General and Eating Disorder Specific Flexibility: Development and Validation of the Eating Disorder Flexibility Index (EDFLIX) Questionnaire.

Dahlgren CL, Hage TW, Wonderlich JA, Stedal K.

Front Psychol. 2019 Apr 2;10:663. doi: 10.3389/fpsyg.2019.00663. eCollection 2019.

11.

Identification of Residues Critical for FPR2 Activation by the Cryptic Peptide Mitocryptide-2 Originating from the Mitochondrial DNA-Encoded Cytochrome b.

Lind S, Gabl M, Holdfeldt A, Mårtensson J, Sundqvist M, Nishino K, Dahlgren C, Mukai H, Forsman H.

J Immunol. 2019 May 1;202(9):2710-2719. doi: 10.4049/jimmunol.1900060. Epub 2019 Mar 22.

PMID:
30902901
12.

Functional selective ATP receptor signaling controlled by the free fatty acid receptor 2 through a novel allosteric modulation mechanism.

Lind S, Holdfeldt A, Mårtensson J, Sundqvist M, Björkman L, Forsman H, Dahlgren C.

FASEB J. 2019 Jun;33(6):6887-6903. doi: 10.1096/fj.201802309R. Epub 2019 Feb 26.

PMID:
30808243
13.

Neutrophil recruitment to inflamed joints can occur without cellular priming.

Björkman L, Christenson K, Davidsson L, Mårtensson J, Amirbeagi F, Welin A, Forsman H, Karlsson A, Dahlgren C, Bylund J.

J Leukoc Biol. 2019 Jun;105(6):1123-1130. doi: 10.1002/JLB.3AB0918-369R. Epub 2018 Dec 20.

PMID:
30570778
14.

Eating disorders in premenstrual dysphoric disorder: a neuroendocrinological pathway to the pathogenesis and treatment of binge eating.

Dahlgren CL, Qvigstad E.

J Eat Disord. 2018 Oct 25;6:35. doi: 10.1186/s40337-018-0222-2. eCollection 2018.

15.

Neutrophil priming that turns natural FFA2R agonists into potent activators of the superoxide generating NADPH-oxidase.

Mårtensson J, Holdfeldt A, Sundqvist M, Gabl M, Kenakin TP, Björkman L, Forsman H, Dahlgren C.

J Leukoc Biol. 2018 Dec;104(6):1117-1132. doi: 10.1002/JLB.2A0318-130RR. Epub 2018 Aug 22.

PMID:
30134499
16.

Evaluation of two commercial CT metal artifact reduction algorithms for use in proton radiotherapy treatment planning in the head and neck area.

Andersson KM, Dahlgren CV, Reizenstein J, Cao Y, Ahnesjö A, Thunberg P.

Med Phys. 2018 Oct;45(10):4329-4344. doi: 10.1002/mp.13115. Epub 2018 Sep 19.

PMID:
30076784
17.

Temporal relationship of sleep apnea and acromegaly: a nationwide study.

Vouzouneraki K, Franklin KA, Forsgren M, Wärn M, Persson JT, Wik H, Dahlgren C, Nilsson AS, Alkebro C, Burman P, Erfurth EM, Wahlberg J, Åkerman AK, Høybye C, Ragnarsson O, Engström BE, Dahlqvist P.

Endocrine. 2018 Nov;62(2):456-463. doi: 10.1007/s12020-018-1694-1. Epub 2018 Jul 31.

18.

Mitocryptides from Human Mitochondrial DNA-Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling Properties.

Gabl M, Sundqvist M, Holdfeldt A, Lind S, Mårtensson J, Christenson K, Marutani T, Dahlgren C, Mukai H, Forsman H.

J Immunol. 2018 May 1;200(9):3269-3282. doi: 10.4049/jimmunol.1701719. Epub 2018 Mar 30.

19.

Similarities and differences between the responses induced in human phagocytes through activation of the medium chain fatty acid receptor GPR84 and the short chain fatty acid receptor FFA2R.

Sundqvist M, Christenson K, Holdfeldt A, Gabl M, Mårtensson J, Björkman L, Dieckmann R, Dahlgren C, Forsman H.

Biochim Biophys Acta Mol Cell Res. 2018 May;1865(5):695-708. doi: 10.1016/j.bbamcr.2018.02.008. Epub 2018 Feb 22.

20.

Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes.

Sundqvist M, Christenson K, Björnsdottir H, Osla V, Karlsson A, Dahlgren C, Speert DP, Fasth A, Brown KL, Bylund J.

Front Immunol. 2017 Dec 21;8:1828. doi: 10.3389/fimmu.2017.01828. eCollection 2017.

21.

Recording a diagnosis of stroke, transient ischaemic attack or myocardial infarction in primary healthcare and the association with dispensation of secondary preventive medication: a registry-based prospective cohort study.

Dahlgren C, Geary L, Hasselström J, Rehnberg C, Schenck-Gustafsson K, Wändell P, Euler MV.

BMJ Open. 2017 Sep 21;7(9):e015723. doi: 10.1136/bmjopen-2016-015723.

22.

Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question.

Winther M, Holdfeldt A, Sundqvist M, Rajabkhani Z, Gabl M, Bylund J, Dahlgren C, Forsman H.

PLoS One. 2017 Sep 21;12(9):e0185132. doi: 10.1371/journal.pone.0185132. eCollection 2017.

23.

Formyl Peptide Receptors in Mice and Men: Similarities and Differences in Recognition of Conventional Ligands and Modulating Lipopeptides.

Winther M, Dahlgren C, Forsman H.

Basic Clin Pharmacol Toxicol. 2018 Feb;122(2):191-198. doi: 10.1111/bcpt.12903. Epub 2017 Nov 28. Review.

24.

FPR2 signaling without β-arrestin recruitment alters the functional repertoire of neutrophils.

Gabl M, Holdfeldt A, Sundqvist M, Lomei J, Dahlgren C, Forsman H.

Biochem Pharmacol. 2017 Dec 1;145:114-122. doi: 10.1016/j.bcp.2017.08.018. Epub 2017 Aug 30.

PMID:
28855087
25.

Reactivation of Gαi-coupled formyl peptide receptors is inhibited by Gαq-selective inhibitors when induced by signals generated by the platelet-activating factor receptor.

Holdfeldt A, Dahlstrand Rudin A, Gabl M, Rajabkhani Z, König GM, Kostenis E, Dahlgren C, Forsman H.

J Leukoc Biol. 2017 Sep;102(3):871-880. doi: 10.1189/jlb.2A0317-086RR. Epub 2017 Jul 31.

PMID:
28760822
26.

Combining Elements from Two Antagonists of Formyl Peptide Receptor 2 Generates More Potent Peptidomimetic Antagonists.

Skovbakke SL, Holdfeldt A, Nielsen C, Hansen AM, Perez-Gassol I, Dahlgren C, Forsman H, Franzyk H.

J Med Chem. 2017 Aug 24;60(16):6991-6997. doi: 10.1021/acs.jmedchem.7b00489. Epub 2017 Aug 10.

PMID:
28700225
27.

Cognitive Remediation Therapy for Adolescents with Anorexia Nervosa-Treatment Satisfaction and the Perception of Change.

Dahlgren CL, Stedal K.

Behav Sci (Basel). 2017 Apr 18;7(2). pii: E23. doi: 10.3390/bs7020023.

28.

Phenol-Soluble Modulin α Peptide Toxins from Aggressive Staphylococcus aureus Induce Rapid Formation of Neutrophil Extracellular Traps through a Reactive Oxygen Species-Independent Pathway.

Björnsdottir H, Dahlstrand Rudin A, Klose FP, Elmwall J, Welin A, Stylianou M, Christenson K, Urban CF, Forsman H, Dahlgren C, Karlsson A, Bylund J.

Front Immunol. 2017 Mar 9;8:257. doi: 10.3389/fimmu.2017.00257. eCollection 2017.

29.

A MULTICENTER, LONGITUDINAL, INTERVENTIONAL, DOUBLE BLIND RANDOMIZED CLINICAL TRIAL IN HEMATOPOIETIC CELL TRANSPLANT RECIPIENTS RESIDING IN REMOTE AREAS: LESSONS LEARNED FROM THE LATE CYTOMEGALOVIRUS PREVENTION TRIAL.

Kimball LE, Stevens-Ayers T, Green ML, Xie H, Flowers ME, Jerome KR, LeBlanc R, Dahlgren C, Nichols WG, Chemaly RF, Papanicolaou G, Boeckh M.

Contemp Clin Trials Commun. 2016 Dec 15;4:84-89. doi: 10.1016/j.conctc.2016.05.002. Epub 2016 May 5.

30.

Eating Disorder Examination Questionnaire (EDE-Q) and Clinical Impairment Assessment (CIA): clinical norms and functional impairment in male and female adults with eating disorders.

Dahlgren CL, Stedal K, Rø Ø.

Nord J Psychiatry. 2017 May;71(4):256-261. doi: 10.1080/08039488.2016.1271452. Epub 2017 Jan 13.

PMID:
28084126
31.

Formylated MHC Class Ib Binding Peptides Activate Both Human and Mouse Neutrophils Primarily through Formyl Peptide Receptor 1.

Winther M, Holdfeldt A, Gabl M, Wang JM, Forsman H, Dahlgren C.

PLoS One. 2016 Dec 1;11(12):e0167529. doi: 10.1371/journal.pone.0167529. eCollection 2016.

32.

All that glisters is not an endophenotype: rethinking endophenotypes in anorexia nervosa.

Micali N, Dahlgren CL.

Eur Child Adolesc Psychiatry. 2016 Nov;25(11):1149-1150. No abstract available.

PMID:
27770295
33.

The peptidomimetic Lau-(Lys-βNSpe)6-NH2 antagonizes formyl peptide receptor 2 expressed in mouse neutrophils.

Skovbakke SL, Winther M, Gabl M, Holdfeldt A, Linden S, Wang JM, Dahlgren C, Franzyk H, Forsman H.

Biochem Pharmacol. 2016 Nov 1;119:56-65. doi: 10.1016/j.bcp.2016.09.004. Epub 2016 Sep 8.

PMID:
27614010
34.

The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment.

Björkman L, Mårtensson J, Winther M, Gabl M, Holdfeldt A, Uhrbom M, Bylund J, Højgaard Hansen A, Pandey SK, Ulven T, Forsman H, Dahlgren C.

Mol Cell Biol. 2016 Sep 26;36(20):2583-95. doi: 10.1128/MCB.00161-16. Print 2016 Oct 15.

35.

The Lipidated Peptidomimetic Lau-((S)-Aoc)-(Lys-βNphe)6-NH2 Is a Novel Formyl Peptide Receptor 2 Agonist That Activates Both Human and Mouse Neutrophil NADPH Oxidase.

Holdfeldt A, Skovbakke SL, Winther M, Gabl M, Nielsen C, Perez-Gassol I, Larsen CJ, Wang JM, Karlsson A, Dahlgren C, Forsman H, Franzyk H.

J Biol Chem. 2016 Sep 16;291(38):19888-99. doi: 10.1074/jbc.M116.736850. Epub 2016 Jul 15.

36.

Data on human neutrophil activation induced by pepducins with amino acid sequences derived from β2AR and CXCR4.

Holdfeldt A, Winther M, Gabl M, Dahlgren C, Forsman H.

Data Brief. 2016 Jun 1;8:411-4. doi: 10.1016/j.dib.2016.05.065. eCollection 2016 Sep.

37.

Basic characteristics of the neutrophil receptors that recognize formylated peptides, a danger-associated molecular pattern generated by bacteria and mitochondria.

Dahlgren C, Gabl M, Holdfeldt A, Winther M, Forsman H.

Biochem Pharmacol. 2016 Aug 15;114:22-39. doi: 10.1016/j.bcp.2016.04.014. Epub 2016 Apr 27. Review.

PMID:
27131862
38.

A pepducin designed to modulate P2Y2R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk mechanism.

Gabl M, Holdfeldt A, Winther M, Oprea T, Bylund J, Dahlgren C, Forsman H.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1228-37. doi: 10.1016/j.bbamcr.2016.03.014. Epub 2016 Mar 18.

39.

Quantification of heterotypic granule fusion in human neutrophils by imaging flow cytometry.

Björnsdottir H, Welin A, Dahlgren C, Karlsson A, Bylund J.

Data Brief. 2015 Dec 17;6:386-93. doi: 10.1016/j.dib.2015.12.003. eCollection 2016 Mar.

40.

Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen species.

Björnsdottir H, Welin A, Michaëlsson E, Osla V, Berg S, Christenson K, Sundqvist M, Dahlgren C, Karlsson A, Bylund J.

Free Radic Biol Med. 2015 Dec;89:1024-35. doi: 10.1016/j.freeradbiomed.2015.10.398. Epub 2015 Nov 4.

PMID:
26459032
41.

Neuropsychological assessment in adolescents with anorexia nervosa - exploring the relationship between self-report and performance-based testing.

Stedal K, Dahlgren CL.

J Eat Disord. 2015 Aug 13;3:27. doi: 10.1186/s40337-015-0062-2. eCollection 2015.

42.

P2Y2 receptor signaling in neutrophils is regulated from inside by a novel cytoskeleton-dependent mechanism.

Gabl M, Winther M, Welin A, Karlsson A, Oprea T, Bylund J, Dahlgren C, Forsman H.

Exp Cell Res. 2015 Aug 15;336(2):242-52. doi: 10.1016/j.yexcr.2015.07.014. Epub 2015 Jul 17.

PMID:
26192818
43.

A neutrophil inhibitory pepducin derived from FPR1 expected to target FPR1 signaling hijacks the closely related FPR2 instead.

Winther M, Gabl M, Welin A, Dahlgren C, Forsman H.

FEBS Lett. 2015 Jul 8;589(15):1832-9. doi: 10.1016/j.febslet.2015.05.050. Epub 2015 Jun 9.

44.

The proteolytically stable peptidomimetic Pam-(Lys-βNSpe)6-NH2 selectively inhibits human neutrophil activation via formyl peptide receptor 2.

Skovbakke SL, Heegaard PM, Larsen CJ, Franzyk H, Forsman H, Dahlgren C.

Biochem Pharmacol. 2015 Jan 15;93(2):182-95. doi: 10.1016/j.bcp.2014.11.004. Epub 2014 Nov 14.

PMID:
25462815
45.

Structural changes of the ligand and of the receptor alters the receptor preference for neutrophil activating peptides starting with a formylmethionyl group.

Forsman H, Winther M, Gabl M, Skovbakke SL, Boulay F, Rabiet MJ, Dahlgren C.

Biochim Biophys Acta. 2015 Jan;1853(1):192-200. doi: 10.1016/j.bbamcr.2014.10.021. Epub 2014 Oct 30.

46.

Olfactomedin-4 autoantibodies give unusual c-ANCA staining patterns with reactivity to a subpopulation of neutrophils.

Amirbeagi F, Thulin P, Pullerits R, Pedersen B, Andersson BA, Dahlgren C, Welin A, Bylund J.

J Leukoc Biol. 2015 Jan;97(1):181-9. doi: 10.1189/jlb.5A0614-311R. Epub 2014 Nov 11.

PMID:
25387833
47.

CFP-10 from Mycobacterium tuberculosis selectively activates human neutrophils through a pertussis toxin-sensitive chemotactic receptor.

Welin A, Björnsdottir H, Winther M, Christenson K, Oprea T, Karlsson A, Forsman H, Dahlgren C, Bylund J.

Infect Immun. 2015 Jan;83(1):205-13. doi: 10.1128/IAI.02493-14. Epub 2014 Oct 20.

48.

A pepducin derived from the third intracellular loop of FPR2 is a partial agonist for direct activation of this receptor in neutrophils but a full agonist for cross-talk triggered reactivation of FPR2.

Gabl M, Winther M, Skovbakke SL, Bylund J, Dahlgren C, Forsman H.

PLoS One. 2014 Oct 10;9(10):e109516. doi: 10.1371/journal.pone.0109516. eCollection 2014.

49.

Antibacterial activity of pepducins, allosterical modulators of formyl peptide receptor signaling.

Winther M, Gabl M, Oprea TI, Jönsson B, Boulay F, Bylund J, Dahlgren C, Forsman H.

Antimicrob Agents Chemother. 2014 May;58(5):2985-8. doi: 10.1128/AAC.02716-13. Epub 2014 Mar 3.

50.

Measurement of respiratory burst products, released or retained, during activation of professional phagocytes.

Bylund J, Björnsdottir H, Sundqvist M, Karlsson A, Dahlgren C.

Methods Mol Biol. 2014;1124:321-38. doi: 10.1007/978-1-62703-845-4_21.

PMID:
24504962

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